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TR200103219T2 - Nöropatik ağrının iyileştirilmesinde kullanım için aroil aminoasil piroller - Google Patents

Nöropatik ağrının iyileştirilmesinde kullanım için aroil aminoasil piroller

Info

Publication number
TR200103219T2
TR200103219T2 TR2001/03219T TR200103219T TR200103219T2 TR 200103219 T2 TR200103219 T2 TR 200103219T2 TR 2001/03219 T TR2001/03219 T TR 2001/03219T TR 200103219 T TR200103219 T TR 200103219T TR 200103219 T2 TR200103219 T2 TR 200103219T2
Authority
TR
Turkey
Prior art keywords
treatment
neuropathic pain
pyrroles
aminoacyl
aroyl
Prior art date
Application number
TR2001/03219T
Other languages
English (en)
Inventor
R. Carson John
M. Pitis Philip
E. Rogers Kathryn
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of TR200103219T2 publication Critical patent/TR200103219T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333Radicals substituted by oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Aroil aminoasil piroller nöropatik agrinin iyilestirilmesinde farmasötik açidan yararli olmaktadir, bu yarar, nöropatik agrinin iyilestirilmesi için kullanimi kapsamaktadir.
TR2001/03219T 1999-02-18 2000-02-17 Nöropatik ağrının iyileştirilmesinde kullanım için aroil aminoasil piroller TR200103219T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12047799P 1999-02-18 1999-02-18

Publications (1)

Publication Number Publication Date
TR200103219T2 true TR200103219T2 (tr) 2002-04-22

Family

ID=22390558

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03219T TR200103219T2 (tr) 1999-02-18 2000-02-17 Nöropatik ağrının iyileştirilmesinde kullanım için aroil aminoasil piroller

Country Status (14)

Country Link
US (2) US6191142B1 (tr)
EP (1) EP1154996B1 (tr)
JP (1) JP2002537247A (tr)
AR (1) AR022620A1 (tr)
AT (1) ATE253556T1 (tr)
AU (1) AU3367500A (tr)
CA (1) CA2361390A1 (tr)
DE (1) DE60006363T2 (tr)
DK (1) DK1154996T3 (tr)
ES (1) ES2209843T3 (tr)
HK (1) HK1041003B (tr)
TR (1) TR200103219T2 (tr)
TW (1) TW562797B (tr)
WO (1) WO2000048584A2 (tr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001271631A1 (en) 2000-06-30 2002-01-14 Ortho-Mcneil Pharmaceutical, Inc. Useful aroyl aminoacyl pyrrole compounds
EP1351950B1 (en) 2000-12-20 2007-08-08 Ortho-McNeil Pharmaceutical, Inc. Isoquinolinyl aroyl pyrrole compounds for the treatment of central nervous system disorders
WO2003057219A1 (en) * 2001-12-27 2003-07-17 Ortho-Mcneil Pharmaceutical Inc. Aroyl pyrrole heteroeryl and methanols useful for treating a central nervous system disorder
JP4428053B2 (ja) 2002-02-05 2010-03-10 味の素株式会社 ガバペンチン若しくはプレガバリンおよびn型カルシウムチャンネル拮抗剤を含有する医薬組成物
HU230403B1 (hu) * 2003-12-19 2016-04-28 Pál Kocsis Nátrium csatorna blokkoló és szerotonin újrafelvétel gátló tartalmú gyógyszerkészítmény
EP2256103A1 (en) 2009-05-07 2010-12-01 Biosynth AG Novel indicator platform

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332736A (en) * 1993-11-01 1994-07-26 Ortho Pharmaceutical Corporation Anti-convulsant aroyl aminoacylpyrroles
US5418236A (en) 1993-12-23 1995-05-23 Ortho Pharmaceutical Corporation Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles
WO1998007447A1 (en) 1996-08-23 1998-02-26 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
US5760007A (en) 1997-07-16 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating neuropathic pain

Also Published As

Publication number Publication date
DK1154996T3 (da) 2004-02-16
US6191142B1 (en) 2001-02-20
EP1154996A2 (en) 2001-11-21
DE60006363D1 (de) 2003-12-11
TW562797B (en) 2003-11-21
DE60006363T2 (de) 2005-07-21
WO2000048584A3 (en) 2000-12-07
JP2002537247A (ja) 2002-11-05
HK1041003A1 (en) 2002-06-28
AR022620A1 (es) 2002-09-04
ES2209843T3 (es) 2004-07-01
HK1041003B (en) 2004-05-07
US20010044452A1 (en) 2001-11-22
CA2361390A1 (en) 2000-08-24
ATE253556T1 (de) 2003-11-15
EP1154996B1 (en) 2003-11-05
AU3367500A (en) 2000-09-04
WO2000048584A2 (en) 2000-08-24
US6369228B2 (en) 2002-04-09

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