TR200100054T2 - Paroksetin metansülfonat - Google Patents
Paroksetin metansülfonatInfo
- Publication number
- TR200100054T2 TR200100054T2 TR2001/00054T TR200100054T TR200100054T2 TR 200100054 T2 TR200100054 T2 TR 200100054T2 TR 2001/00054 T TR2001/00054 T TR 2001/00054T TR 200100054 T TR200100054 T TR 200100054T TR 200100054 T2 TR200100054 T2 TR 200100054T2
- Authority
- TR
- Turkey
- Prior art keywords
- paroxetine methanesulfonate
- paroxetine
- methanesulfonate
- therapy
- pharmaceutical compositions
- Prior art date
Links
- SHIJTGJXUHTGGZ-RVXRQPKJSA-N (3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonate Chemical compound CS(O)(=O)=O.C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 SHIJTGJXUHTGGZ-RVXRQPKJSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Paroksetin metansülfonat, hazirlama prosesleri, bunu içeren farmasötik terkipler ve terapide kullanimi açiklanmaktadir.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9814316.7A GB9814316D0 (en) | 1998-07-02 | 1998-07-02 | Novel compounds |
| GBGB9821732.6A GB9821732D0 (en) | 1998-10-06 | 1998-10-06 | Novel compound |
| GBGB9902935.7A GB9902935D0 (en) | 1999-02-10 | 1999-02-10 | Novel compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200100054T2 true TR200100054T2 (tr) | 2001-06-21 |
Family
ID=27269380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00054T TR200100054T2 (tr) | 1998-07-02 | 1999-04-23 | Paroksetin metansülfonat |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US6063927A (tr) |
| EP (5) | EP1089996B1 (tr) |
| JP (1) | JP2002519422A (tr) |
| KR (1) | KR20010053336A (tr) |
| CN (1) | CN1127502C (tr) |
| AR (2) | AR011759A1 (tr) |
| AT (4) | ATE251155T1 (tr) |
| AU (4) | AU732211C (tr) |
| BE (3) | BE1011664A6 (tr) |
| BR (1) | BR9911682A (tr) |
| CA (1) | CA2269999A1 (tr) |
| CH (1) | CH689805A8 (tr) |
| DE (5) | DE19918588A1 (tr) |
| DK (7) | DK0970955T3 (tr) |
| ES (4) | ES2209428T3 (tr) |
| FI (2) | FI112077B (tr) |
| FR (2) | FR2780728B1 (tr) |
| GB (5) | GB2339428A (tr) |
| GR (3) | GR990100140A (tr) |
| HU (1) | HUP0102334A3 (tr) |
| IE (5) | IE20000633A1 (tr) |
| IL (1) | IL140628A (tr) |
| IT (1) | IT1312540B1 (tr) |
| LU (1) | LU90388B1 (tr) |
| NL (4) | NL1011875C2 (tr) |
| NO (1) | NO319030B1 (tr) |
| NZ (1) | NZ509180A (tr) |
| PL (1) | PL345214A1 (tr) |
| PT (4) | PT102291B (tr) |
| SE (1) | SE9901462A0 (tr) |
| SI (3) | SI1020464T1 (tr) |
| SK (1) | SK20262000A3 (tr) |
| TR (1) | TR200100054T2 (tr) |
| WO (1) | WO2000001694A1 (tr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5998401A (en) * | 1995-02-28 | 1999-12-07 | Eli Lilly And Company | Naphthyl compounds, intermediates, compositions, and methods |
| SK285545B6 (sk) * | 1997-02-27 | 2007-03-01 | Ajinomoto Co., Inc. | Zariadenie na kryštalizáciu a spôsob kryštalizácie |
| SK283394B6 (sk) * | 1997-06-10 | 2003-07-01 | Synthon B. V. | Zlúčeniny 4-fenylpiperidínu a jej farmaceuticky prijateľné soli, spôsob ich prípravy, liečivo s ich obsahom a ich použitie |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| US20040028582A1 (en) * | 1999-03-10 | 2004-02-12 | Smithkline Beecham Corporation | Crystallization process for producing fine crystal products |
| USPP12225P2 (en) | 1999-06-01 | 2001-11-27 | Florfis Ag | Geranium plant named ‘Fislamda’ |
| WO2000078290A2 (en) * | 1999-06-22 | 2000-12-28 | Smithkline Beecham P.L.C. | Pharmaceutical composition comprising a salt of paroxetine |
| ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
| GB0003232D0 (en) * | 2000-02-11 | 2000-04-05 | Smithkline Beecham Plc | Novel composition |
| US6306435B1 (en) | 2000-06-26 | 2001-10-23 | Yung Shin Pharmaceutical Industrial Co. Ltd. | Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same |
| GB0015981D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
| CA2418038A1 (en) * | 2000-08-28 | 2002-03-07 | Synthon B.V. | Paroxetine compositions and processes for making the same |
| DE20100529U1 (de) * | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
| NL1017421C2 (nl) * | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| US20040225128A1 (en) * | 2001-08-02 | 2004-11-11 | Callewaert George Leo | Paroxetine isethionate salt, process of preparation and use in the treatment of depression |
| EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| US20050266082A1 (en) * | 2004-05-26 | 2005-12-01 | Patel Satishkumar A | Preparation of stable paroxetine HC1 ER tablets using a melt granulation process |
| EP1778183B1 (en) * | 2004-08-18 | 2018-06-27 | Synthon B.V. | Liquid paroxetine compositions |
| US20060039975A1 (en) * | 2004-08-20 | 2006-02-23 | Zalman Vilkov | Paroxetine formulations |
| KR100672184B1 (ko) | 2004-09-21 | 2007-01-19 | 주식회사종근당 | 파록세틴의 콜린산 또는 콜린산 유도체 염 |
| WO2006110553A2 (en) * | 2005-04-07 | 2006-10-19 | Xy, Inc. | Flow path conditioner system |
| WO2007058998A2 (en) * | 2005-11-14 | 2007-05-24 | Auspex Pharmaceuticals, Inc. | Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties |
| US8722884B2 (en) * | 2005-12-01 | 2014-05-13 | Verastem, Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| KR20090118110A (ko) * | 2007-03-09 | 2009-11-17 | 노파르티스 아게 | 3-(1h-인돌-3-일)-4-[2-(4-메틸-피페라진-1-일)-퀴나졸린-4-일]-피롤-2,5-디온의 염 |
| US20100249166A1 (en) | 2007-09-19 | 2010-09-30 | Xy, Inc. | Differential evaporation potentiated disinfectant system |
| US8119688B2 (en) * | 2007-09-19 | 2012-02-21 | Xy, Llc | Differential evaporation potentiated disinfectant system |
| FR2926552B1 (fr) * | 2008-01-23 | 2010-03-26 | Biocodex | Procede de preparation de particules de stiripentol ayant une granulometrie definie |
| CN103961333B (zh) * | 2014-05-07 | 2020-02-21 | 浙江华海药业股份有限公司 | 甲磺酸帕罗西汀胶囊及其制备方法 |
| CN104523645A (zh) * | 2014-11-20 | 2015-04-22 | 美吉斯制药(厦门)有限公司 | 甲磺酸帕罗西汀片芯及其包衣片的制备方法 |
| US11111373B2 (en) | 2018-12-05 | 2021-09-07 | Chi Mei Corporation | Polymethacrylate composition and optical device made therefrom, and display apparatus |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE99678C (tr) * | ||||
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| US4585777A (en) * | 1984-02-07 | 1986-04-29 | A/S Ferrosan | (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT |
| GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
| EP0190496A3 (en) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Piperidine derivatives having a gastro-intestinal activity |
| GB8431478D0 (en) * | 1984-12-13 | 1985-01-23 | Beecham Group Plc | Compounds |
| GB8520154D0 (en) * | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
| DE3680184D1 (de) * | 1985-08-10 | 1991-08-14 | Beecham Group Plc | Verfahren zur herstellung von arylpiperidincarbinol. |
| DE3677712D1 (de) * | 1985-10-21 | 1991-04-04 | Honda Motor Co Ltd | Methode zur steuerung des spulenstroms eines magnetventils, das die saufluftmenge eines innenverbrennungsmotors steuert. |
| ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| GB8626936D0 (en) * | 1986-11-11 | 1986-12-10 | Ferrosan As | Treatment |
| JPS63141967A (ja) * | 1986-11-21 | 1988-06-14 | エイ・エッチ・ロビンス・カンパニー・インコーポレーテッド | 抗アレルギー薬として有用な1−アリールオキシー4−[(4−アリール)−1−ピペラジニル]−2−ブタノール |
| GB8714707D0 (en) * | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
| DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
| DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
| AU658155B2 (en) * | 1990-11-24 | 1995-04-06 | Beecham Group Plc | Use of paroxetine for the treatment of senile dementia, or anorexia |
| GB9209687D0 (en) * | 1992-05-06 | 1992-06-17 | Smithkline Beecham Plc | Novel process |
| US5258517A (en) * | 1992-08-06 | 1993-11-02 | Sepracor, Inc. | Method of preparing optically pure precursors of paroxetine |
| JP2773587B2 (ja) * | 1992-11-30 | 1998-07-09 | 東レ株式会社 | O,o´−ジアシル酒石酸無水物の製造法 |
| US5276042A (en) * | 1993-04-16 | 1994-01-04 | Crenshaw Roger T | Treatment of premature ejaculation |
| US5546683A (en) * | 1993-09-29 | 1996-08-20 | Clark; George J. | Bucket attachment device with remote controlled retractable pins |
| IT1274241B (it) * | 1993-12-03 | 1997-07-15 | Smithkline Beecham Farma | Complessi agente terapeutico/matrice polimerica dotati di migliorate caratteristiche di sapore e composizioni farmaceutiche che li contengono |
| GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
| US5668134A (en) * | 1994-01-28 | 1997-09-16 | G. D. Searle & Co. | Method for preventing or reducing photosensitivity and/or phototoxicity reactions to medications |
| GB9402029D0 (en) * | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| CA2143070C (en) * | 1994-02-22 | 2001-12-18 | Pankaj Modi | Oral controlled release liquid suspension pharmaceutical formulation |
| EP0714663A3 (en) * | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potentiation of drug responses by serotonin 1A receptor antagonists |
| AR001982A1 (es) * | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion |
| GB2297550B (en) * | 1995-02-06 | 1997-04-09 | Smithkline Beecham Plc | Paroxetine hydrochloride anhydrate substantially free of bound organic solvent |
| WO1996031197A1 (en) * | 1995-04-03 | 1996-10-10 | Abbott Laboratories | Homogeneous mixtures of low temperature-melting drugs and additives for controlled release |
| HUP9900318A3 (en) * | 1995-05-17 | 2001-09-28 | Novo Nordisk As | Process for preparing 4-aryl-piperidine derivatives |
| JP2813768B2 (ja) * | 1995-05-24 | 1998-10-22 | 農林水産省家畜衛生試験場長 | 口蹄疫診断用ペプチドおよび当該ペプチドを含有する口蹄疫診断用抗原 |
| GB9514842D0 (en) * | 1995-07-20 | 1995-09-20 | Smithkline Beecham Plc | Novel formulation |
| CA2234640A1 (en) * | 1995-10-31 | 1997-05-09 | Merck & Co., Inc. | Process for preparing substituted azetidinones |
| IT1276160B1 (it) * | 1995-11-22 | 1997-10-27 | Recordati Chem Pharm | Composizioni farmaceutiche orali a pronto rilascio per sospensioni estemporanee |
| GB9526645D0 (en) * | 1995-12-28 | 1996-02-28 | Chiroscience Ltd | Stereoselective synthesis |
| ES2117557B1 (es) * | 1996-02-29 | 1999-07-01 | Ferrer Int | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
| JP3446468B2 (ja) * | 1996-04-15 | 2003-09-16 | 旭硝子株式会社 | ピペリジンカルビノール類の製造方法 |
| CA2206592A1 (en) * | 1996-05-30 | 1997-11-30 | Shu-Zhong Wang | Method of producing amorphous paroxetine hydrochloride |
| JP3882224B2 (ja) * | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
| EP1394160A1 (en) * | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for preparing crystalline paroxetin hydrochloride |
| HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
| US5672609A (en) * | 1996-07-18 | 1997-09-30 | Eli Lilly And Company | Pyridine compounds, intermediates compositions and methods of use |
| CA2187128A1 (en) * | 1996-10-04 | 1997-06-26 | K. S. Keshava Murthy | New and useful polymorph of anhydrous paroxetine hydrochloride |
| SK283394B6 (sk) * | 1997-06-10 | 2003-07-01 | Synthon B. V. | Zlúčeniny 4-fenylpiperidínu a jej farmaceuticky prijateľné soli, spôsob ich prípravy, liečivo s ich obsahom a ich použitie |
| EP1053234A1 (en) * | 1998-02-06 | 2000-11-22 | Smithkline Beecham Plc | Salts of paroxetine |
| CN1300286A (zh) * | 1998-03-16 | 2001-06-20 | 史密丝克莱恩比彻姆有限公司 | 帕罗西丁的晶形 |
| HUP0103651A3 (en) * | 1998-04-09 | 2002-12-28 | Smithkline Beecham Plc | Paroxetine maleate and process for its preparation |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
| DE20100529U1 (de) * | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
-
1999
- 1999-04-20 CH CH00723/99A patent/CH689805A8/fr not_active IP Right Cessation
- 1999-04-23 DE DE19918588A patent/DE19918588A1/de not_active Ceased
- 1999-04-23 GR GR990100140A patent/GR990100140A/el not_active IP Right Cessation
- 1999-04-23 DE DE29907248U patent/DE29907248U1/de not_active Expired - Lifetime
- 1999-04-23 US US09/299,060 patent/US6063927A/en not_active Expired - Fee Related
- 1999-04-23 IE IE20000633A patent/IE20000633A1/en not_active IP Right Cessation
- 1999-04-23 EP EP99918159A patent/EP1089996B1/en not_active Expired - Lifetime
- 1999-04-23 PL PL99345214A patent/PL345214A1/xx not_active Application Discontinuation
- 1999-04-23 IE IE20000894A patent/IES20000894A2/en not_active Application Discontinuation
- 1999-04-23 AT AT99918159T patent/ATE251155T1/de not_active IP Right Cessation
- 1999-04-23 JP JP2000558097A patent/JP2002519422A/ja active Pending
- 1999-04-23 GB GB9920332A patent/GB2339428A/en not_active Withdrawn
- 1999-04-23 NZ NZ509180A patent/NZ509180A/en unknown
- 1999-04-23 FI FI990922A patent/FI112077B/fi active
- 1999-04-23 PT PT102291A patent/PT102291B/pt not_active IP Right Cessation
- 1999-04-23 AR ARP990101885A patent/AR011759A1/es not_active Application Discontinuation
- 1999-04-23 IE IE19990343 patent/IES81166B2/en not_active IP Right Cessation
- 1999-04-23 PT PT79901275T patent/PT1020464E/pt unknown
- 1999-04-23 SK SK2026-2000A patent/SK20262000A3/sk unknown
- 1999-04-23 DE DE69911774T patent/DE69911774T2/de not_active Expired - Fee Related
- 1999-04-23 AU AU23928/99A patent/AU732211C/en not_active Ceased
- 1999-04-23 ES ES99918159T patent/ES2209428T3/es not_active Expired - Lifetime
- 1999-04-23 HU HU0102334A patent/HUP0102334A3/hu unknown
- 1999-04-23 PT PT99303151T patent/PT970955E/pt unknown
- 1999-04-23 KR KR1020007015099A patent/KR20010053336A/ko not_active Withdrawn
- 1999-04-23 ES ES009900849A patent/ES2158778B1/es not_active Expired - Fee Related
- 1999-04-23 DK DK99303151T patent/DK0970955T3/da active
- 1999-04-23 DK DK199900176U patent/DK199900176U3/da not_active IP Right Cessation
- 1999-04-23 CN CN99810281A patent/CN1127502C/zh not_active Expired - Fee Related
- 1999-04-23 EP EP02078483A patent/EP1288214A1/en not_active Withdrawn
- 1999-04-23 CA CA002269999A patent/CA2269999A1/en not_active Abandoned
- 1999-04-23 DK DK199900554A patent/DK199900554A/da not_active Application Discontinuation
- 1999-04-23 FR FR9905185A patent/FR2780728B1/fr not_active Expired - Fee Related
- 1999-04-23 FI FI990190U patent/FI4209U1/fi not_active IP Right Cessation
- 1999-04-23 IE IE19990344A patent/IE990344A1/en not_active IP Right Cessation
- 1999-04-23 LU LU90388A patent/LU90388B1/fr active
- 1999-04-23 AU AU36191/99A patent/AU3619199A/en not_active Abandoned
- 1999-04-23 NO NO19991944A patent/NO319030B1/no unknown
- 1999-04-23 IE IE20000893A patent/IES20000893A2/en not_active IP Right Cessation
- 1999-04-23 BE BE9900294A patent/BE1011664A6/fr not_active IP Right Cessation
- 1999-04-23 TR TR2001/00054T patent/TR200100054T2/tr unknown
- 1999-04-23 NL NL1011875A patent/NL1011875C2/nl not_active IP Right Cessation
- 1999-04-23 GB GB0216752A patent/GB2377637A/en not_active Withdrawn
- 1999-04-23 SE SE9901462A patent/SE9901462A0/sv not_active Application Discontinuation
- 1999-04-23 AU AU23938/99A patent/AU713877B3/en not_active Ceased
- 1999-04-23 GB GB9909505A patent/GB2336364B/en not_active Revoked
- 1999-04-23 PT PT99918159T patent/PT1089996E/pt unknown
- 1999-04-23 DK DK99918159T patent/DK1089996T3/da active
- 1999-04-23 IL IL14062899A patent/IL140628A/en not_active IP Right Cessation
- 1999-04-23 WO PCT/GB1999/001253 patent/WO2000001694A1/en not_active Ceased
- 1999-04-23 SI SI9930009T patent/SI1020464T1/xx unknown
- 1999-04-23 EP EP00201289A patent/EP1020463A1/en not_active Withdrawn
- 1999-04-23 AT AT0027999U patent/AT3185U3/de not_active IP Right Cessation
- 1999-04-23 GB GB0026487A patent/GB2352395B/en not_active Expired - Fee Related
- 1999-04-23 EP EP00201290A patent/EP1020464B1/en not_active Revoked
- 1999-04-23 AT AT99303151T patent/ATE195121T1/de not_active IP Right Cessation
- 1999-04-23 DE DE69900007T patent/DE69900007T2/de not_active Revoked
- 1999-04-23 BR BR9911682-0A patent/BR9911682A/pt not_active Application Discontinuation
- 1999-04-23 SI SI9930482T patent/SI1089996T1/xx unknown
- 1999-04-23 SI SI9930002T patent/SI0970955T1/xx unknown
- 1999-04-23 BE BE9900293A patent/BE1012403A5/fr not_active IP Right Cessation
- 1999-04-23 EP EP99303151A patent/EP0970955B1/en not_active Revoked
- 1999-04-23 GB GB0119695A patent/GB2367003A/en not_active Withdrawn
- 1999-04-23 AU AU23937/99A patent/AU713131B3/en not_active Ceased
- 1999-04-23 IT IT1999MI000866A patent/IT1312540B1/it active
- 1999-04-23 NL NL1011874A patent/NL1011874C1/nl not_active IP Right Cessation
- 1999-04-23 ES ES99303151T patent/ES2149044T3/es not_active Expired - Lifetime
- 1999-04-26 AR ARP990101908A patent/AR018197A1/es unknown
- 1999-06-08 NL NL1012271A patent/NL1012271C2/nl not_active IP Right Cessation
- 1999-06-08 NL NL1012272A patent/NL1012272C1/nl not_active IP Right Cessation
- 1999-06-15 DK DK199900234U patent/DK199900234U4/da not_active IP Right Cessation
- 1999-12-23 BE BE9900832A patent/BE1012420A6/fr not_active IP Right Cessation
-
2000
- 2000-04-10 AT AT00201290T patent/ATE202777T1/de not_active IP Right Cessation
- 2000-04-10 DK DK00201290T patent/DK1020464T3/da active
- 2000-04-10 ES ES00201290T patent/ES2157881T3/es not_active Expired - Lifetime
- 2000-04-10 DE DE60000003T patent/DE60000003T2/de not_active Revoked
- 2000-09-05 GR GR20000402015T patent/GR3034328T3/el not_active IP Right Cessation
- 2000-11-08 FR FR0014325A patent/FR2802098A1/fr active Pending
- 2000-12-27 DK DK200000390U patent/DK200000390U1/da not_active IP Right Cessation
-
2001
- 2001-03-14 US US09/805,812 patent/US20010023253A1/en not_active Abandoned
- 2001-07-11 GR GR20010401061T patent/GR3036208T3/el not_active IP Right Cessation
- 2001-09-21 US US09/960,033 patent/US20020035130A1/en not_active Abandoned
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2002
- 2002-06-18 US US10/174,380 patent/US20020193406A1/en not_active Abandoned
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