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TH148539A - Carba-nucleoside analogs substituted at the 1' position for antiviral therapy - Google Patents

Carba-nucleoside analogs substituted at the 1' position for antiviral therapy

Info

Publication number
TH148539A
TH148539A TH0901001785A TH0901001785A TH148539A TH 148539 A TH148539 A TH 148539A TH 0901001785 A TH0901001785 A TH 0901001785A TH 0901001785 A TH0901001785 A TH 0901001785A TH 148539 A TH148539 A TH 148539A
Authority
TH
Thailand
Prior art keywords
carba
triazinyl
nucleoside analogs
antiviral therapy
analogs substituted
Prior art date
Application number
TH0901001785A
Other languages
Thai (th)
Other versions
TH148539B (en
TH901001785A (en
TH0901001785B (en
TH93210B (en
Inventor
ยู คิม ฉุง
บัตเลอร์ โธมัส
จาง ลี่จุน
โฉ เอซอพ
ซอนเดอร์ส โอลิเวอร์
Original Assignee
จีเลด ไซเอนเซส
Filing date
Publication date
Publication of TH901001785A publication Critical patent/TH901001785A/en
Application filed by จีเลด ไซเอนเซส filed Critical จีเลด ไซเอนเซส
Publication of TH148539B publication Critical patent/TH148539B/en
Publication of TH148539A publication Critical patent/TH148539A/en
Publication of TH0901001785B publication Critical patent/TH0901001785B/en
Publication of TH93210B publication Critical patent/TH93210B/en

Links

Abstract

DC60 (03/07/52) ได้จัดให้มี ไพร์โรโล[1,2-f][1,2,4]ไตรอะซินิล, อิมิดาโซ[1,5-f][1,2,4]ไตรอะซินิล, อิมิดา โซ[1,2-f][1,2,4]ไตรอะซินิล, และ [1,2,4]ไตรอะโซโล[4,3-f][1,2,4]ไตรอะซินิล นิวคลีโอไซด์, นิวคลีโอไซด์ฟอสเฟต และโพรดรักของสารเหล่านั้น โดยที่ตำแหน่ง 1' ของน้ำตาลนิวคลีโอไซต์ ถูกแทนที่ สารประกอบ, องค์ประกอบ, และวิธีการซึ่งถูกจัดให้เป็นประโยชน์สำหรับการบำบัดการ ติดเชื้อไวรัส Flaviviridae โดยเฉพาะการติดเชื้อตับอักเสบ CDC60 (03/07/52) provides pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates, and their prodrugs, where the 1' position of the nucleoside sugar is substituted. Compounds, compositions, and methods of application are available for the treatment of Flaviviridae virus infections, particularly hepatitis C infection.

TH0901001785A 2009-04-22 Carba-nucleoside analogs substituted at the 1' position for antiviral therapy TH93210B (en)

Publications (5)

Publication Number Publication Date
TH901001785A TH901001785A (en)
TH148539B TH148539B (en) 2016-04-07
TH148539A true TH148539A (en) 2016-04-07
TH0901001785B TH0901001785B (en) 2016-04-07
TH93210B TH93210B (en) 2023-04-25

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