UA102687C2 - 1'-substituted carba-nucleoside analogs for antiviral treatment - Google Patents
1'-substituted carba-nucleoside analogs for antiviral treatmentInfo
- Publication number
- UA102687C2 UA102687C2 UAA201013029A UAA201013029A UA102687C2 UA 102687 C2 UA102687 C2 UA 102687C2 UA A201013029 A UAA201013029 A UA A201013029A UA A201013029 A UAA201013029 A UA A201013029A UA 102687 C2 UA102687 C2 UA 102687C2
- Authority
- UA
- Ukraine
- Prior art keywords
- triazinyl
- nucleoside analogs
- antiviral treatment
- substituted
- substituted carba
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title abstract 4
- 230000000840 anti-viral effect Effects 0.000 title 1
- 125000004306 triazinyl group Chemical group 0.000 abstract 3
- 241000710781 Flaviviridae Species 0.000 abstract 1
- 208000005176 Hepatitis C Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000010710 hepatitis C virus infection Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000003835 nucleoside group Chemical group 0.000 abstract 1
- -1 nucleoside phosphates Chemical class 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Provided are pyrrolo[1,2-f][1,2,4]triazinyl, imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections. Formula (I), each Xor Xis independently C-Ror N.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4726308P | 2008-04-23 | 2008-04-23 | |
| PCT/US2009/041447 WO2009132135A1 (en) | 2008-04-23 | 2009-04-22 | 1' -substituted carba-nucleoside analogs for antiviral treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA102687C2 true UA102687C2 (en) | 2013-08-12 |
Family
ID=47915801
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201013029A UA102687C2 (en) | 2008-04-23 | 2009-04-22 | 1'-substituted carba-nucleoside analogs for antiviral treatment |
| UAA201013030A UA103477C2 (en) | 2008-04-23 | 2009-04-22 | Carba-nucleoside analogs for antiviral treatment |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201013030A UA103477C2 (en) | 2008-04-23 | 2009-04-22 | Carba-nucleoside analogs for antiviral treatment |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR107618A2 (en) |
| UA (2) | UA102687C2 (en) |
-
2009
- 2009-04-22 UA UAA201013029A patent/UA102687C2/en unknown
- 2009-04-22 UA UAA201013030A patent/UA103477C2/en unknown
-
2017
- 2017-02-14 AR ARP170100362A patent/AR107618A2/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| UA103477C2 (en) | 2013-10-25 |
| AR107618A2 (en) | 2018-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG179194A1 (en) | 2' -fluoro substituted carba-nucleoside analogs for antiviral treatment | |
| CO6321235A2 (en) | CARBA-NUCLEOSID ANALOGS 1 SUBSTITUTED FOR ANTIVIRAL TREATMENT | |
| MX345562B (en) | Carba-nucleoside analogs for antiviral treatment. | |
| PH12013500311B1 (en) | 2' -fluoro substituted carba-nucleoside analogs for antiviral treatment | |
| EA201691623A1 (en) | 2'-Fluoro-substituted Carbanulosis Analogs for antiviral treatment | |
| WO2012142523A3 (en) | 1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment | |
| UY33414A (en) | ? NUCLEOSID PROPHARMS 1 '? CARBA SUBSTITUTED FOR ANTIVIRAL TREATMENT, COMPOSITIONS AND ITS USE ?. | |
| PH12013500035A1 (en) | Methods and compounds for treating paramyxoviridae virus infections | |
| WO2012158811A3 (en) | Purine monophosphate prodrugs for treatment of viral infections | |
| EA201390142A1 (en) | 2'-Fluoro-substituted Carbanulosis Analogs for antiviral treatment | |
| SG179445A1 (en) | Nucleoside phosphoramidate prodrugs | |
| AU2012242978A1 (en) | 2'-Cyano Substituted Nucleoside Derivatives and methods of use thereof for the treatment of viral diseases | |
| NZ706985A (en) | 2’-chloro nucleoside analogs for hcv infection | |
| UA102687C2 (en) | 1'-substituted carba-nucleoside analogs for antiviral treatment | |
| TH148539A (en) | Carba-nucleoside analogs substituted at the 1' position for antiviral therapy | |
| TH145025A (en) | Carba-nucleoside-like compounds with 2'-fluorosubstitutions for antiviral therapy | |
| CY1115086T1 (en) | CARBON-NUCLEOZITE ANALOGS FOR ANTI-EDUCATION | |
| HK40106755A (en) | Nucleosides and nucleotides analogs as antiviral agents | |
| WO2007059330A3 (en) | Cubane nucleoside analogs |