SU1268169A1 - Method of treatment of bone fractures - Google Patents

Abstract

This invention relates to traumatology. The purpose of the invention is to reduce the duration of treatment for bone fractures. In the first 10 days, patients are given ascorbic acid and thiamine bromide in a daily dose parenterally, 2 times a day after 8-10 hours. After 20 days, the daily dose of these vitamins is given once a day. At the same time, during the entire period of treatment, potassium orotat is administered at a rate of 0.5 g 3 times a day. The result of treatment is judged according to clinical, radiological and biochemical studies. 1 tab. with s

Description

This invention relates specifically to traumatology. The purpose of the invention is to reduce the cure due to the fact that during the first 10 days the daily dose of ascorbic acid and thiamine brp of the Foreign Ministry is taken once and administered parenterally 2 times a day in 10 hours. The method is carried out as follows: first 10 days ascorbic acid and thiomin bro ™ MFA are administered to the patients in a daily dose of parenteral. but 2 times a day after h. After the next 20 days. The daily dose of the indicated vitamins is administered once a day, and during the entire period of treatment, complex treatment is carried out using potassium orotate. The results of treatment are judged according to the data of clinical X-ray and biochemical studies. Example. Patient B., 57 years old mechanic, was taken to the clinic with diabetes: closed comminuted fracture of the upper third of the bones of the left goal or fragments displaced. Upon admission to the hospital from

swelling, cutting soreness, 30 viscous.

crepitus debris, pathological mobility in the upper third of the left tibia. After damage to the nature of the fracture by means of rantgenological examination and appropriate anesthesia, manual reposition (straightening) of fragments and immobilization of the left tibia with a deep deep plaster longue are performed. bandage.

In order to accelerate the healing of bone fractures, the patient is treated by the proposed method: in the first 10 days. after the fracture, 5 ml of a 5% ascorbic acid solution and an i sh solution of thiamine bromide, 2 times a day after 10 hours, are injected intracutaneously in the next 20 days. 5 mg of ascorbic acid solution and 1 ml of 6% thiamine bromide solution were administered once a day. Orota potassium 0.5 g 3 times a day, the patient takes orally for 1 h before meals for 30 days

In the course of treatment, regular dynamic observation of the patient, research of laboratory analyzes of blood, urine and other biochemical analyzes are carried out.

Radiographically after 20 days. after fracture, the formation of a good bone callus connecting the ends of bone fragments is noted.

In 30 days after the fracture on the repeated control radiograph, further consolidation of the periosteal and endosteal callus in the left bone fracture zone is noted

lower leg The patient was enrolled for outpatient treatment.

The patient began to walk without crutches after 2 months. after fracture. Radiographically after 3 months 20 days. after the fracture a complete healing of the fracture is noted with the complete disappearance of the line of fracture of the bones of the left tibia, he began to work in the main profession after 3 months. 20 di. after fracture of the bones of the left leg.

Claims (1)

In this observation, the application of the proposed method made it possible to achieve an extremely high result of treatment. Clinical GI, the radiological period of consolidation of this fracture was only 20 days, the terms of inpatient treatment 9 On admission the concentration of ascorbic acid and thiamine bromide in the blood was 37.46 -nmol / ton and 1.80 µg% correspondingly, and their excretion in the urine — 17.4 mg and 130.2 µg, respectively 10 hours after the administration of the vitamins, each time there was a sharp decrease in the content of ascorbic acid and thiamine bromine Blood ida 32, 5 nmol / l and l, 44jHl, 5 µg%, respectively, and their excretion in the urine was sharply reduced, for ascorbic acid 11, 5 mg, for thiamine bromide 121.5 jfl, 3 µg. Normalization of vitamin C, By in blood and urine was achieved by repeated (after 10 hours) administration of ascorbic acid and thiamine bromide in dosages during the first 10 days, and in the next 20 days with a single daily administration of these vitamins according to the proposed method. Clinically consolidation of a fracture occurred 20 days after the injury, as evidenced by the disappearance of the crepitus of fragments, pathological mobility during limb movements after removal of the gypsum for 3 days 30 days, recovery time 11 2 di. In this observation, the treatment carried out reduced the time of consolidation for clinical and fentgenic logical signs for 10 days, the period of inpatient treatment by 20 days, the period of temporary disability for 2 months, 10 days. The table shows the comparative results of bone fracture treatment. From the table it can be seen that the proposed method allows to reduce the clinical and radiological periods of the formation of an average of 10 days, the terms of inpatient treatment by 12 d 9 and temporary disability by 1. 2 months. Claims of treatment of bone fractures by administering drugs, characterized in that, to reduce the duration of treatment, ascorbic acid and thiamine bromide are administered as a daily dose for the first 10 days parenterally twice a day every 8 days, After 20 days, the daily dose of the indicated vitamins is administered once, and during the entire period of treatment, potassium orotate is added. one- 90 40 2- 3- thirty 6 50 45 5.5 38