SK4922002A3 - Imidazole derivative as phosphodiesterase vii inhibitor, use thereof and pharmaceutical composition containing the same - Google Patents
Imidazole derivative as phosphodiesterase vii inhibitor, use thereof and pharmaceutical composition containing the same Download PDFInfo
- Publication number
- SK4922002A3 SK4922002A3 SK492-2002A SK4922002A SK4922002A3 SK 4922002 A3 SK4922002 A3 SK 4922002A3 SK 4922002 A SK4922002 A SK 4922002A SK 4922002 A3 SK4922002 A3 SK 4922002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- disease
- imidazol
- formula
- treatment
- benzopyrano
- Prior art date
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- 239000002606 phosphodiesterase VII inhibitor Substances 0.000 title claims abstract description 19
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 10
- 150000002460 imidazoles Chemical class 0.000 title abstract description 6
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- 125000000217 alkyl group Chemical group 0.000 claims abstract description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 4
- 229910052801 chlorine Inorganic materials 0.000 claims abstract description 4
- 229910052731 fluorine Inorganic materials 0.000 claims abstract description 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims abstract description 3
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims abstract description 3
- 229910052794 bromium Inorganic materials 0.000 claims abstract description 3
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims abstract description 3
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19950647A DE19950647A1 (de) | 1999-10-21 | 1999-10-21 | Imidazolderivate als Phosphodiesterase VII-Hemmer |
| PCT/EP2000/009926 WO2001029049A2 (fr) | 1999-10-21 | 2000-10-10 | Derives d'imidazole utilises comme inhibiteurs de la phosphodiesterase vii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK4922002A3 true SK4922002A3 (en) | 2002-09-10 |
Family
ID=7926352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK492-2002A SK4922002A3 (en) | 1999-10-21 | 2000-10-10 | Imidazole derivative as phosphodiesterase vii inhibitor, use thereof and pharmaceutical composition containing the same |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1222193B1 (fr) |
| JP (1) | JP2003512381A (fr) |
| KR (1) | KR20020060201A (fr) |
| CN (1) | CN1382146A (fr) |
| AR (1) | AR026198A1 (fr) |
| AT (1) | ATE247121T1 (fr) |
| AU (1) | AU780788B2 (fr) |
| BR (1) | BR0014922A (fr) |
| CA (1) | CA2388314C (fr) |
| CZ (1) | CZ293751B6 (fr) |
| DE (2) | DE19950647A1 (fr) |
| DK (1) | DK1222193T3 (fr) |
| ES (1) | ES2200957T3 (fr) |
| HU (1) | HUP0203139A3 (fr) |
| MX (1) | MXPA02003952A (fr) |
| NO (1) | NO20021846D0 (fr) |
| PL (1) | PL355020A1 (fr) |
| PT (1) | PT1222193E (fr) |
| RU (1) | RU2259199C2 (fr) |
| SK (1) | SK4922002A3 (fr) |
| WO (1) | WO2001029049A2 (fr) |
| ZA (1) | ZA200203995B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60222931T2 (de) * | 2001-12-13 | 2008-07-10 | Asubio Pharma Co., Ltd. | Pyrazolopyrimidinonderivate mit pde7-hemmender wirkung |
| DE10163991A1 (de) * | 2001-12-24 | 2003-07-03 | Merck Patent Gmbh | Pyrrolo-pyrimidine |
| JP2006219373A (ja) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体 |
| JP2006219374A (ja) | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するイミダゾトリアジノン誘導体 |
| PL1775298T3 (pl) | 2004-07-01 | 2013-08-30 | Daiichi Sankyo Co Ltd | Pochodna tienopirazolowa wykazująca aktywność hamowania PDE7 |
| US8637528B2 (en) | 2007-03-27 | 2014-01-28 | Omeros Corporation | Use of PDE7 inhibitors for the treatment of movement disorders |
| EP2139475B1 (fr) | 2007-03-27 | 2014-12-17 | Omeros Corporation | Inhibiteurs de PDE7 pour le traitement de troubles du mouvement |
| US20120115849A1 (en) | 2010-11-08 | 2012-05-10 | Demopulos Gregory A | Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors |
| US9220715B2 (en) | 2010-11-08 | 2015-12-29 | Omeros Corporation | Treatment of addiction and impulse-control disorders using PDE7 inhibitors |
| EP4572765A1 (fr) | 2022-08-18 | 2025-06-25 | Mitodicure GmbH | Utilisation d'un agent thérapeutique ayant une activité inhibitrice de phosphodiestérase-7 pour le traitement et la prévention de maladies associées à la fatigue, à l'épuisement et/ou à l'intolérance à l'effort chroniques |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4305954A (en) * | 1981-02-11 | 1981-12-15 | E. I. Du Pont De Nemours And Company | Antiinflammatory 3,4-dihydro(or 1,4-dihydro)-2-[(substituted)thio]-[1]benzopyrano[3,4-d]imidazoles and their corresponding sulfoxides and sulfones |
| CN1051085C (zh) * | 1993-08-19 | 2000-04-05 | 詹森药业有限公司 | 取代的二氢吡喃并吡啶及其制法、用途和含其的药物组合物 |
| DE19632423A1 (de) * | 1996-08-12 | 1998-02-19 | Merck Patent Gmbh | Thienopyrimidine |
| TW591030B (en) * | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| WO2000023091A2 (fr) * | 1998-10-15 | 2000-04-27 | Bioimage A/S | Interventions therapeutiques specifiques obtenues par interference avec redistribution et ou ciblage |
| WO2000068230A1 (fr) * | 1999-05-05 | 2000-11-16 | Darwin Discovery Limited | Derives de 9-(1,2,3,4-tetrahydronapththalene-1-yle)-1,9-dihydropurine-6-un inhibiteurs de pde7 |
-
1999
- 1999-10-21 DE DE19950647A patent/DE19950647A1/de not_active Withdrawn
-
2000
- 2000-10-10 PT PT00972714T patent/PT1222193E/pt unknown
- 2000-10-10 AU AU11356/01A patent/AU780788B2/en not_active Ceased
- 2000-10-10 PL PL00355020A patent/PL355020A1/xx unknown
- 2000-10-10 CA CA002388314A patent/CA2388314C/fr not_active Expired - Fee Related
- 2000-10-10 HU HU0203139A patent/HUP0203139A3/hu unknown
- 2000-10-10 AT AT00972714T patent/ATE247121T1/de not_active IP Right Cessation
- 2000-10-10 DE DE50003309T patent/DE50003309D1/de not_active Expired - Lifetime
- 2000-10-10 DK DK00972714T patent/DK1222193T3/da active
- 2000-10-10 RU RU2002111413/15A patent/RU2259199C2/ru not_active IP Right Cessation
- 2000-10-10 SK SK492-2002A patent/SK4922002A3/sk unknown
- 2000-10-10 MX MXPA02003952A patent/MXPA02003952A/es unknown
- 2000-10-10 ES ES00972714T patent/ES2200957T3/es not_active Expired - Lifetime
- 2000-10-10 CZ CZ20021251A patent/CZ293751B6/cs not_active IP Right Cessation
- 2000-10-10 WO PCT/EP2000/009926 patent/WO2001029049A2/fr not_active Ceased
- 2000-10-10 BR BR0014922-5A patent/BR0014922A/pt not_active IP Right Cessation
- 2000-10-10 KR KR1020027004903A patent/KR20020060201A/ko not_active Withdrawn
- 2000-10-10 JP JP2001531847A patent/JP2003512381A/ja active Pending
- 2000-10-10 CN CN00814402A patent/CN1382146A/zh active Pending
- 2000-10-10 EP EP00972714A patent/EP1222193B1/fr not_active Expired - Lifetime
- 2000-10-20 AR ARP000105542A patent/AR026198A1/es unknown
-
2002
- 2002-04-19 NO NO20021846A patent/NO20021846D0/no not_active Application Discontinuation
- 2002-05-20 ZA ZA200203995A patent/ZA200203995B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001029049A2 (fr) | 2001-04-26 |
| NO20021846L (no) | 2002-04-19 |
| JP2003512381A (ja) | 2003-04-02 |
| RU2259199C2 (ru) | 2005-08-27 |
| BR0014922A (pt) | 2002-06-11 |
| WO2001029049A3 (fr) | 2001-11-01 |
| PT1222193E (pt) | 2003-12-31 |
| ZA200203995B (en) | 2003-10-29 |
| HUP0203139A3 (en) | 2004-12-28 |
| DK1222193T3 (da) | 2003-12-01 |
| ATE247121T1 (de) | 2003-08-15 |
| DE19950647A1 (de) | 2001-04-26 |
| ES2200957T3 (es) | 2004-03-16 |
| AU1135601A (en) | 2001-04-30 |
| EP1222193B1 (fr) | 2003-08-13 |
| MXPA02003952A (es) | 2004-09-06 |
| CZ293751B6 (cs) | 2004-07-14 |
| EP1222193A2 (fr) | 2002-07-17 |
| HUP0203139A2 (hu) | 2003-01-28 |
| CZ20021251A3 (cs) | 2002-07-17 |
| AU780788B2 (en) | 2005-04-14 |
| DE50003309D1 (de) | 2003-09-18 |
| KR20020060201A (ko) | 2002-07-16 |
| CA2388314A1 (fr) | 2001-04-26 |
| CA2388314C (fr) | 2009-06-16 |
| NO20021846D0 (no) | 2002-04-19 |
| CN1382146A (zh) | 2002-11-27 |
| AR026198A1 (es) | 2003-01-29 |
| PL355020A1 (en) | 2004-03-22 |
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