SK281538B6 - Kŕmna prísada na inaktiváciu mykotoxínov, jej použitie a spôsob výroby - Google Patents
Kŕmna prísada na inaktiváciu mykotoxínov, jej použitie a spôsob výroby Download PDFInfo
- Publication number
- SK281538B6 SK281538B6 SK1678-96A SK167896A SK281538B6 SK 281538 B6 SK281538 B6 SK 281538B6 SK 167896 A SK167896 A SK 167896A SK 281538 B6 SK281538 B6 SK 281538B6
- Authority
- SK
- Slovakia
- Prior art keywords
- feed
- feed additive
- mycotoxins
- additive according
- enzyme preparation
- Prior art date
Links
- 231100000678 Mycotoxin Toxicity 0.000 title claims abstract description 45
- 239000002636 mycotoxin Substances 0.000 title claims abstract description 45
- 238000000034 method Methods 0.000 title claims description 12
- 230000008569 process Effects 0.000 title claims description 4
- 239000000654 additive Substances 0.000 title abstract description 4
- 230000000996 additive effect Effects 0.000 title abstract description 4
- 239000003674 animal food additive Substances 0.000 claims abstract description 42
- 102000004190 Enzymes Human genes 0.000 claims abstract description 39
- 108090000790 Enzymes Proteins 0.000 claims abstract description 39
- 241001465754 Metazoa Species 0.000 claims abstract description 29
- 238000002360 preparation method Methods 0.000 claims abstract description 21
- 210000001035 gastrointestinal tract Anatomy 0.000 claims abstract description 14
- 230000002779 inactivation Effects 0.000 claims abstract description 13
- 101000693619 Starmerella bombicola Lactone esterase Proteins 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 6
- 241000894006 Bacteria Species 0.000 claims abstract description 5
- 244000005700 microbiome Species 0.000 claims abstract description 5
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 15
- 239000011707 mineral Substances 0.000 claims description 15
- BXFOFFBJRFZBQZ-QYWOHJEZSA-N T-2 toxin Chemical compound C([C@@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 BXFOFFBJRFZBQZ-QYWOHJEZSA-N 0.000 claims description 10
- 239000011148 porous material Substances 0.000 claims description 8
- 229930195730 Aflatoxin Natural products 0.000 claims description 7
- 239000005409 aflatoxin Substances 0.000 claims description 7
- 241001508784 Kazachstania telluris Species 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 241000235070 Saccharomyces Species 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 239000010457 zeolite Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 230000001186 cumulative effect Effects 0.000 claims description 3
- LINOMUASTDIRTM-QGRHZQQGSA-N deoxynivalenol Chemical compound C([C@@]12[C@@]3(C[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 LINOMUASTDIRTM-QGRHZQQGSA-N 0.000 claims description 3
- 229930002954 deoxynivalenol Natural products 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- -1 roridine Natural products 0.000 claims description 3
- 239000002002 slurry Substances 0.000 claims description 3
- LINOMUASTDIRTM-UHFFFAOYSA-N vomitoxin hydrate Natural products OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 LINOMUASTDIRTM-UHFFFAOYSA-N 0.000 claims description 3
- GOTYCQXAAKQUOD-VINXHBPISA-N (1R,3R,8R,12S,13R,18E,20E,24R,25S,26S)-12-hydroxy-5,13,25-trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,18,20-triene-26,2'-oxirane]-6,11,17,22-tetrone Chemical compound C[C@@H]1CCOC(=O)/C=C/C=C/C(=O)O[C@@H]2C[C@@H]3[C@]4([C@]2([C@]5(CC(=O)C(=C[C@H]5O3)C)COC(=O)[C@H]1O)C)CO4 GOTYCQXAAKQUOD-VINXHBPISA-N 0.000 claims description 2
- LAQCZBYXNRANFU-WQOXNDGTSA-N Crotocin Chemical compound C([C@@]12[C@@]3(C)[C@@]4(C)[C@H]5O[C@H]5C(C)=C[C@H]4O[C@@H]1C[C@H]3OC(=O)\C=C/C)O2 LAQCZBYXNRANFU-WQOXNDGTSA-N 0.000 claims description 2
- XGCUCFKWVIWWNW-UHFFFAOYSA-N Fusarenone X Natural products CC(=O)OC1C(O)C2OC3C=C(C)C(=O)C(O)C3(CO)C1(C)C21CO1 XGCUCFKWVIWWNW-UHFFFAOYSA-N 0.000 claims description 2
- ZGOCMMMDEQOCDU-UOBFQKKOSA-N Isobaccharinol Natural products CC(O)C1OCC(O)C2(C)OC2C(=O)OCC34CC(O)C(=CC3OC5CC(OC(=O)C=C/C=C/1)C4(C)C56CO6)C ZGOCMMMDEQOCDU-UOBFQKKOSA-N 0.000 claims description 2
- 239000005909 Kieselgur Substances 0.000 claims description 2
- UVPSSGJTBLNVRE-UHFFFAOYSA-N Moniliformin Natural products O=C1C(OC)=CC(=O)C=2C1=C1C(=O)C(OC)=CC(=O)C1=CC=2 UVPSSGJTBLNVRE-UHFFFAOYSA-N 0.000 claims description 2
- UKOTXHQERFPCBU-YQPARWETSA-N Nivalenol Chemical compound C([C@]12[C@@]3([C@H](O)[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 UKOTXHQERFPCBU-YQPARWETSA-N 0.000 claims description 2
- ITCSWEBPTQLQKN-UHFFFAOYSA-N Nivalenol Natural products CC1=CC2OC3C(O)C(O)C(C2(CO)CC1=O)C34CO4 ITCSWEBPTQLQKN-UHFFFAOYSA-N 0.000 claims description 2
- ZGOCMMMDEQOCDU-DVRXXRMKSA-N baccharinol Chemical compound C([C@@]12[C@]3(C)[C@H]4C[C@H]1O[C@@H]1C=C(C)[C@H](O)C[C@@]13COC(=O)[C@H]1O[C@]1(C)[C@H](O)CO[C@H](\C=C\C=C/C(=O)O4)[C@H](O)C)O2 ZGOCMMMDEQOCDU-DVRXXRMKSA-N 0.000 claims description 2
- LAQCZBYXNRANFU-VQRCBPKLSA-N crotocin Natural products CC=C/C(=O)O[C@@H]1C[C@H]2O[C@@H]3C=C(C)[C@@H]4O[C@@H]4[C@]3(C)[C@]1(C)[C@@]25CO5 LAQCZBYXNRANFU-VQRCBPKLSA-N 0.000 claims description 2
- XGCUCFKWVIWWNW-CAYGJDLQSA-N fusarenone x Chemical compound C([C@@]12[C@@]3(C)[C@@]4(CO)[C@H](O)C(=O)C(C)=C[C@H]4O[C@@H]1[C@H](O)[C@H]3OC(=O)C)O2 XGCUCFKWVIWWNW-CAYGJDLQSA-N 0.000 claims description 2
- KGPQKNJSZNXOPV-UHFFFAOYSA-N moniliformin Chemical compound OC1=CC(=O)C1=O KGPQKNJSZNXOPV-UHFFFAOYSA-N 0.000 claims description 2
- PNKLMTPXERFKEN-ZIOSACBISA-N mycotoxin ht 2 Chemical compound C([C@]12[C@]3(C)[C@H](O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 PNKLMTPXERFKEN-ZIOSACBISA-N 0.000 claims description 2
- 229930194532 satratoxin Natural products 0.000 claims description 2
- MBMQEIFVQACCCH-UHFFFAOYSA-N trans-Zearalenon Natural products O=C1OC(C)CCCC(=O)CCCC=CC2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-UHFFFAOYSA-N 0.000 claims description 2
- 229930190906 verrucarin Natural products 0.000 claims description 2
- MBMQEIFVQACCCH-QBODLPLBSA-N zearalenone Chemical compound O=C1O[C@@H](C)CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-QBODLPLBSA-N 0.000 claims description 2
- 239000004348 Glyceryl diacetate Substances 0.000 claims 1
- 239000000287 crude extract Substances 0.000 claims 1
- IRXDUBNENLKYTC-OINWIYPRSA-N deacetylanguidin Chemical compound C([C@@]12[C@]3(C)[C@H](O)[C@@H](O)[C@H]1O[C@@H]1C=C(C)CC[C@@]13COC(=O)C)O2 IRXDUBNENLKYTC-OINWIYPRSA-N 0.000 claims 1
- 235000019443 glyceryl diacetate Nutrition 0.000 claims 1
- AADMRFXTAGXWSE-UHFFFAOYSA-N monoacetoxyscirpenol Natural products CC(=O)OC1C(O)C2OC3(C)C=C(C)CCC3(CO)C1(C)C24CO4 AADMRFXTAGXWSE-UHFFFAOYSA-N 0.000 claims 1
- 108010017796 epoxidase Proteins 0.000 abstract description 8
- 229940088598 enzyme Drugs 0.000 description 29
- 235000010755 mineral Nutrition 0.000 description 13
- 238000001179 sorption measurement Methods 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 102000005486 Epoxide hydrolase Human genes 0.000 description 6
- 108020002908 Epoxide hydrolase Proteins 0.000 description 6
- OQIQSTLJSLGHID-WNWIJWBNSA-N aflatoxin B1 Chemical compound C=1([C@@H]2C=CO[C@@H]2OC=1C=C(C1=2)OC)C=2OC(=O)C2=C1CCC2=O OQIQSTLJSLGHID-WNWIJWBNSA-N 0.000 description 6
- 230000015556 catabolic process Effects 0.000 description 6
- 238000006731 degradation reaction Methods 0.000 description 6
- 235000012631 food intake Nutrition 0.000 description 6
- 230000037406 food intake Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 230000002378 acidificating effect Effects 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000009257 reactivity Effects 0.000 description 4
- 239000003053 toxin Substances 0.000 description 4
- XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 241000282887 Suidae Species 0.000 description 3
- JYIBXUUINYLWLR-UHFFFAOYSA-N aluminum;calcium;potassium;silicon;sodium;trihydrate Chemical compound O.O.O.[Na].[Al].[Si].[K].[Ca] JYIBXUUINYLWLR-UHFFFAOYSA-N 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 229910001603 clinoptilolite Inorganic materials 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 229940079919 digestives enzyme preparation Drugs 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 3
- 229910052622 kaolinite Inorganic materials 0.000 description 3
- 244000144972 livestock Species 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 150000002924 oxiranes Chemical class 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000002115 aflatoxin B1 Substances 0.000 description 2
- 229930020125 aflatoxin-B1 Natural products 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- YGANSGVIUGARFR-UHFFFAOYSA-N dipotassium dioxosilane oxo(oxoalumanyloxy)alumane oxygen(2-) Chemical compound [O--].[K+].[K+].O=[Si]=O.O=[Al]O[Al]=O YGANSGVIUGARFR-UHFFFAOYSA-N 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 2
- 230000009931 harmful effect Effects 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 208000011873 mild conjunctivitis Diseases 0.000 description 2
- 229910052627 muscovite Inorganic materials 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 210000004894 snout Anatomy 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- XSUVNTHNQMGPIL-LACSLYJWSA-N 709j50qeiq Chemical compound C([C@@]12[C@@]3([C@H](O)C[C@H]1O[C@@H]1C=C(CC[C@@]13C)C)C)O2 XSUVNTHNQMGPIL-LACSLYJWSA-N 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 101100352919 Caenorhabditis elegans ppm-2 gene Proteins 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- AUGQEEXBDZWUJY-ZLJUKNTDSA-N Diacetoxyscirpenol Chemical compound C([C@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@@H]1C=C(C)CC[C@@]13COC(=O)C)O2 AUGQEEXBDZWUJY-ZLJUKNTDSA-N 0.000 description 1
- AUGQEEXBDZWUJY-UHFFFAOYSA-N Diacetoxyscirpenol Natural products CC(=O)OCC12CCC(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C11CO1 AUGQEEXBDZWUJY-UHFFFAOYSA-N 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 108010024636 Glutathione Proteins 0.000 description 1
- 102000005720 Glutathione transferase Human genes 0.000 description 1
- 108010070675 Glutathione transferase Proteins 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 241000143973 Libytheinae Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- XSUVNTHNQMGPIL-UHFFFAOYSA-N Trichodermol Natural products CC12CCC(C)=CC1OC1CC(O)C2(C)C11CO1 XSUVNTHNQMGPIL-UHFFFAOYSA-N 0.000 description 1
- 208000020560 abdominal swelling Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000021052 average daily weight gain Nutrition 0.000 description 1
- 235000021053 average weight gain Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000002144 chemical decomposition reaction Methods 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000007515 enzymatic degradation Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 229960003180 glutathione Drugs 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 125000005842 heteroatom Chemical group 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 125000000686 lactone group Chemical group 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229930183344 ochratoxin Natural products 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 235000018770 reduced food intake Nutrition 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/14—Pretreatment of feeding-stuffs with enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
- A23K30/20—Dehydration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01017—Gluconolactonase (3.1.1.17)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/01—Carboxylic ester hydrolases (3.1.1)
- C12Y301/01025—1,4-Lactonase (3.1.1.25)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y303/00—Hydrolases acting on ether bonds (3.3)
- C12Y303/02—Ether hydrolases (3.3.2)
- C12Y303/02003—Epoxide hydrolase (3.3.2.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Animal Husbandry (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0035794U AT504U1 (de) | 1994-10-19 | 1994-10-19 | Futtermittelzusatz und verwendung desselben zur inaktivierung von mykotoxinen in futtermitteln bzw. im verdauungstrakt von tieren sowie verfahren zur herstellung eines futtermittels |
| PCT/AT1995/000204 WO1996012414A1 (fr) | 1994-10-19 | 1995-10-18 | Additif de fourrage pour inactiver des mycotoxines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK167896A3 SK167896A3 (en) | 1997-06-04 |
| SK281538B6 true SK281538B6 (sk) | 2001-04-09 |
Family
ID=3488466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1678-96A SK281538B6 (sk) | 1994-10-19 | 1995-10-18 | Kŕmna prísada na inaktiváciu mykotoxínov, jej použitie a spôsob výroby |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0786945B1 (fr) |
| JP (1) | JP2983639B2 (fr) |
| KR (1) | KR100218974B1 (fr) |
| CN (1) | CN1092027C (fr) |
| AT (2) | AT504U1 (fr) |
| AU (1) | AU3736595A (fr) |
| BR (1) | BR9509399A (fr) |
| CA (1) | CA2192983C (fr) |
| CZ (1) | CZ285840B6 (fr) |
| DE (1) | DE59504703D1 (fr) |
| ES (1) | ES2128086T3 (fr) |
| HR (1) | HRP950526B1 (fr) |
| HU (1) | HU220703B1 (fr) |
| IL (1) | IL115650A (fr) |
| PL (1) | PL180329B1 (fr) |
| SK (1) | SK281538B6 (fr) |
| TW (1) | TW322418B (fr) |
| WO (1) | WO1996012414A1 (fr) |
| YU (1) | YU66295A (fr) |
| ZA (1) | ZA958786B (fr) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RO118757B1 (ro) * | 1996-11-22 | 2003-10-30 | Pioneer Hi-Bred International, Inc. | Metodă de degradare a moniliforminei prin intermediul bacteriei din specia ochrobactrum |
| AT406166B (de) | 1997-12-30 | 2000-03-27 | Erber Erich Kg | Mikroorganismus, verfahren zur gewinnung desselben sowie futtermittelzusatz |
| WO2000004160A1 (fr) * | 1998-07-15 | 2000-01-27 | Pioneer Hi-Bred International, Inc. | Polynucleotides d'aminopolyolamineoxydase, polypeptides associes, et leur modes d'utilisation |
| WO2000004159A1 (fr) * | 1998-07-15 | 2000-01-27 | Pioneer Hi-Bred International, Inc. | Polynucleotides et polypeptides associes de l'enzyme aminopolyolamineoxydase, et procedes d'utilisation |
| US6538177B1 (en) * | 1998-07-15 | 2003-03-25 | Pioneer Hi-Bred International, Inc. | Compositions and methods for fumonisin detoxification |
| US6943279B1 (en) | 1999-07-12 | 2005-09-13 | Pioneer Hi-Bred International, Inc. | Amino polyol amine oxidase polynucleotides and related polypeptides and methods of use |
| EP1119616A2 (fr) | 1998-10-07 | 2001-08-01 | Maxygen, Inc. | Rearrangement d'adn pour produire des acides nucleiques de detoxication contre les mycotoxines |
| US7347997B1 (en) | 1998-12-21 | 2008-03-25 | Erber Aktiengesellschaft | Method of using a feedstuff additive |
| US6388171B1 (en) | 1999-07-12 | 2002-05-14 | Pioneer Hi-Bred International, Inc. | Compositions and methods for fumonisin detoxification |
| AU5099699A (en) * | 1999-07-14 | 2001-02-05 | Curagen Corporation | Compositions and methods for fumonisin detoxification |
| US6812380B2 (en) | 2001-03-27 | 2004-11-02 | Pioneer Hi-Bred International, Inc. | Compositions and methods of zearalenone detoxification |
| AT413540B (de) * | 2001-12-20 | 2006-03-15 | Erber Ag | Mikroorganismus, welcher ochratoxine sowie ochratoxine und zearalenone entgiftet, sowie verfahren und verwendung hiefür |
| AT501359B1 (de) * | 2004-11-16 | 2007-10-15 | Erber Ag | Verfahren und mikroorganismus zur entgiftung von fumonisinen sowie verwendung und futtermittelzusatz |
| GB0621792D0 (en) * | 2006-11-01 | 2006-12-13 | Mann Stephen P | Composition |
| CA2708795A1 (fr) * | 2007-12-14 | 2009-06-25 | Novozymes A/S | Procede de decomposition de la zearalenone dans un produit d'alimentation pour animaux utilisant de la laccase |
| CN101902924B (zh) | 2007-12-20 | 2013-09-11 | 诺维信公司 | 用于饲料产品的解毒的角质酶 |
| WO2009109607A2 (fr) * | 2008-03-05 | 2009-09-11 | Novozymes A/S | Détoxification de produits alimentaires |
| DK2387410T3 (en) * | 2009-01-14 | 2016-11-07 | Alltech Inc | Gærsammensætninger admixed with the clay, and methods of using same |
| US8318475B2 (en) | 2009-01-14 | 2012-11-27 | Alltech, Inc. | Clay interlaced yeast compositions and methods of utilizing the same |
| WO2012113827A1 (fr) | 2011-02-24 | 2012-08-30 | Eucodis Bioscience Gmbh | Enzymes de traitement d'aliments pour animaux |
| PL219782B1 (pl) | 2012-11-22 | 2015-07-31 | Inst Biotechnologii Przemysłu Rolno Spożywczego Im Prof Wacława Dąbrowskieg | Nowy szczep bakterii Lactobacillus buchneri A oraz wieloskładnikowy preparat do konserwowania roślin wysokoskrobiowych |
| CN104799132A (zh) * | 2015-04-30 | 2015-07-29 | 邹忠义 | 一种t-2毒素的酵母菌发酵去除方法 |
| EP3278674A1 (fr) | 2016-08-03 | 2018-02-07 | Clariant International Ltd | Utilisation d'un adsorbant pour l'élimination du désoxynivalénol de l'alimentation animale |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI77359C (fi) * | 1986-08-22 | 1989-03-10 | Suomen Sokeri Oy | Foderfix och foerfarande foer framstaellning av densamma. |
| FI81484C (fi) * | 1987-04-06 | 1990-11-12 | Cultor Oy | Metod foer behandling av foderraovara, foderraovara och foderblandning. |
| AU659796B2 (en) * | 1990-03-07 | 1995-06-01 | Engelhard Corporation | Animal feed additive and method for inactivating mycotoxins present in animal feeds |
| AT397756B (de) * | 1990-08-10 | 1994-06-27 | Interpremix Futtermittel Und P | Futtermittelzusatz |
| US5445956A (en) * | 1993-08-13 | 1995-08-29 | The Regents Of The University Of California | Recombinant soluble epoxide hydrolase |
-
1994
- 1994-10-19 AT AT0035794U patent/AT504U1/de not_active IP Right Cessation
-
1995
- 1995-10-17 IL IL11565095A patent/IL115650A/xx not_active IP Right Cessation
- 1995-10-18 DE DE59504703T patent/DE59504703D1/de not_active Expired - Fee Related
- 1995-10-18 HU HU9603556A patent/HU220703B1/hu not_active IP Right Cessation
- 1995-10-18 BR BR9509399A patent/BR9509399A/pt not_active Application Discontinuation
- 1995-10-18 AT AT95935284T patent/ATE175073T1/de not_active IP Right Cessation
- 1995-10-18 SK SK1678-96A patent/SK281538B6/sk unknown
- 1995-10-18 ES ES95935284T patent/ES2128086T3/es not_active Expired - Lifetime
- 1995-10-18 EP EP95935284A patent/EP0786945B1/fr not_active Expired - Lifetime
- 1995-10-18 HR HRGM357/94A patent/HRP950526B1/xx not_active IP Right Cessation
- 1995-10-18 JP JP8513525A patent/JP2983639B2/ja not_active Expired - Lifetime
- 1995-10-18 CN CN95195287A patent/CN1092027C/zh not_active Expired - Lifetime
- 1995-10-18 PL PL95319755A patent/PL180329B1/pl unknown
- 1995-10-18 AU AU37365/95A patent/AU3736595A/en not_active Abandoned
- 1995-10-18 WO PCT/AT1995/000204 patent/WO1996012414A1/fr not_active Ceased
- 1995-10-18 KR KR1019970701443A patent/KR100218974B1/ko not_active Expired - Fee Related
- 1995-10-18 CA CA002192983A patent/CA2192983C/fr not_active Expired - Fee Related
- 1995-10-18 CZ CZ963683A patent/CZ285840B6/cs not_active IP Right Cessation
- 1995-10-18 ZA ZA958786A patent/ZA958786B/xx unknown
- 1995-10-19 YU YU66295A patent/YU66295A/sh unknown
- 1995-10-30 TW TW084111448A patent/TW322418B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW322418B (en) | 1997-12-11 |
| MX9702642A (es) | 1997-07-31 |
| EP0786945B1 (fr) | 1998-12-30 |
| ATE175073T1 (de) | 1999-01-15 |
| WO1996012414A1 (fr) | 1996-05-02 |
| YU66295A (sh) | 1998-05-15 |
| PL319755A1 (en) | 1997-08-18 |
| AU3736595A (en) | 1996-05-15 |
| KR100218974B1 (ko) | 1999-09-01 |
| IL115650A (en) | 1999-07-14 |
| CA2192983C (fr) | 1999-09-07 |
| CA2192983A1 (fr) | 1996-05-02 |
| JPH09511657A (ja) | 1997-11-25 |
| HRP950526A2 (en) | 1997-04-30 |
| PL180329B1 (pl) | 2001-01-31 |
| HUT76374A (en) | 1997-08-28 |
| CZ368396A3 (en) | 1997-06-11 |
| ZA958786B (en) | 1996-05-13 |
| ES2128086T3 (es) | 1999-05-01 |
| EP0786945A1 (fr) | 1997-08-06 |
| JP2983639B2 (ja) | 1999-11-29 |
| HRP950526B1 (en) | 1999-12-31 |
| HU9603556D0 (en) | 1997-02-28 |
| HU220703B1 (hu) | 2002-04-29 |
| KR970705344A (ko) | 1997-10-09 |
| DE59504703D1 (de) | 1999-02-11 |
| CN1158554A (zh) | 1997-09-03 |
| CZ285840B6 (cs) | 1999-11-17 |
| CN1092027C (zh) | 2002-10-09 |
| BR9509399A (pt) | 1997-11-04 |
| IL115650A0 (en) | 1996-01-19 |
| SK167896A3 (en) | 1997-06-04 |
| AT504U1 (de) | 1995-12-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SK281538B6 (sk) | Kŕmna prísada na inaktiváciu mykotoxínov, jej použitie a spôsob výroby | |
| US10575539B2 (en) | Additive for selenium-containing forage | |
| ES2559842T3 (es) | Procedimiento para el tratamiento de ensilaje forrajero para rumiantes, así como aditivo para el ensilaje forrajero | |
| CN109554356B (zh) | 一种含葡萄糖氧化酶和酿酒酵母的霉菌毒素生物降解剂及其应用 | |
| CN115669803B (zh) | 一种改善肠道健康、去臭除味的微生态饲料及其制备方法 | |
| CN111772041A (zh) | 一种饲料用广谱缓释型酸化剂及其制备方法 | |
| KR20140055882A (ko) | 온실가스 저감용 친환경 반추동물용 가축사료 | |
| EP1871481B1 (fr) | Procede d'allongement de la periode de mobilite saisonniere de poissons | |
| CN106359906A (zh) | 锌离子抗菌饲料的制备方法 | |
| CN107960543B (zh) | 一种乳仔猪用甘氨酸型添加剂预混合饲料 | |
| CN107619839A (zh) | 一种降低呕吐毒素发酵麸皮及其生产方法和应用 | |
| US4966917A (en) | Methods for improving feed utilization and lactation in ruminant animals | |
| CN101731178B (zh) | 养殖环境调节剂、制备方法及其在畜禽养殖业中的应用 | |
| CN111248356A (zh) | 一种预防疾病的固态混合型饲料添加剂 | |
| CN119969309B (zh) | 一种提高彭泽鲫粘孢子虫抗病力的养殖方法 | |
| MXPA97002642A (en) | Additive for forage and its employment to deactivate mycotoxins in forage or in digestive animal duct, as well as procedure for the elaboration of a forr | |
| KR100676837B1 (ko) | 미생물을 이용한 기초화장품 액상성분의 제조방법 | |
| KR20090102378A (ko) | 쑥을 주원료로 하는 천연 살균 소독제 및 그 제조방법 | |
| KR20010019252A (ko) | 다목적 사료 첨가제 및 그의 제조방법 | |
| US4883820A (en) | Methods for improving feed utilization and lactation in ruminant animals | |
| US4801618A (en) | Methods for improving feed utilization and lactation in ruminant animals | |
| US4895951A (en) | Heterocyclic diamides and method for improving feed utilization and lactation in ruminant animals | |
| CN120918296A (zh) | 一种食叶草鲜叶发酵饲料及其制备方法 | |
| CN110720559A (zh) | 改善仔猪腹泻的饲料添加剂 |