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SK1052000A3 - 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno[2,3-d] pyrimidine derivatives, their preparation and use as 5ht antagonists - Google Patents

3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno[2,3-d] pyrimidine derivatives, their preparation and use as 5ht antagonists Download PDF

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Publication number
SK1052000A3
SK1052000A3 SK105-2000A SK1052000A SK1052000A3 SK 1052000 A3 SK1052000 A3 SK 1052000A3 SK 1052000 A SK1052000 A SK 1052000A SK 1052000 A3 SK1052000 A3 SK 1052000A3
Authority
SK
Slovakia
Prior art keywords
group
tetrahydro
ethyl
thieno
naphthyl
Prior art date
Application number
SK105-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Gerd Steiner
Uta Dullweber
Dorothea Starck
Alfred Bach
Karsten Wicke
Hans-Juergen Teschendorf
Francisco Javier Garcia-Ladona
Franz Emling
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of SK1052000A3 publication Critical patent/SK1052000A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK105-2000A 1997-08-08 1998-07-23 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno[2,3-d] pyrimidine derivatives, their preparation and use as 5ht antagonists SK1052000A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19734444A DE19734444A1 (de) 1997-08-08 1997-08-08 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
PCT/EP1998/004633 WO1999007711A1 (fr) 1997-08-08 1998-07-23 Derives de 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine 3-substitues, leur preparation et leur utilisation comme antagonistes de 5ht

Publications (1)

Publication Number Publication Date
SK1052000A3 true SK1052000A3 (en) 2000-08-14

Family

ID=7838438

Family Applications (1)

Application Number Title Priority Date Filing Date
SK105-2000A SK1052000A3 (en) 1997-08-08 1998-07-23 3-substituted 3,4,5,7-tetrahydro-pyrrolo[3',4':4,5]thieno[2,3-d] pyrimidine derivatives, their preparation and use as 5ht antagonists

Country Status (25)

Country Link
US (1) US6355647B1 (fr)
EP (1) EP1003752A1 (fr)
JP (1) JP2001512734A (fr)
KR (1) KR20010022658A (fr)
CN (1) CN1267303A (fr)
AR (1) AR016594A1 (fr)
AU (1) AU749539B2 (fr)
BG (1) BG104151A (fr)
BR (1) BR9811091A (fr)
CA (1) CA2300391A1 (fr)
CO (1) CO4960665A1 (fr)
CZ (1) CZ290678B6 (fr)
DE (1) DE19734444A1 (fr)
HR (1) HRP980435A2 (fr)
HU (1) HUP0101311A3 (fr)
ID (1) ID24222A (fr)
IL (1) IL134161A0 (fr)
NO (1) NO20000605D0 (fr)
NZ (1) NZ502657A (fr)
PL (1) PL340726A1 (fr)
SK (1) SK1052000A3 (fr)
TR (1) TR200000371T2 (fr)
TW (1) TW513435B (fr)
WO (1) WO1999007711A1 (fr)
ZA (1) ZA987114B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0216027D0 (en) * 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
US20040048874A1 (en) * 2001-05-22 2004-03-11 Bardsley Hazel Judith New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
CA2512022A1 (fr) * 2003-01-13 2004-07-29 Dynogen Pharmaceuticals, Inc. Methode pour traiter des nausees, des vomissements, des haut-le-coeur ou une association de ces symptomes
AU2004204825B2 (en) * 2003-01-13 2007-07-19 Dynogen Pharmaceuticals, Inc. Method of treating functional bowel disorders
DE602004007225T2 (de) * 2003-04-04 2008-03-06 Dynogen Pharmaceuticals Inc., Waltham Methode zur behandlung von erkrankungen der unteren harnwege
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7375814B2 (en) * 2005-03-11 2008-05-20 Sandia Corporation Natural gas leak mapper
US20060293309A1 (en) * 2005-03-28 2006-12-28 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
WO2020183011A1 (fr) 2019-03-14 2020-09-17 Institut Curie Inhibiteurs de htr1d et leurs utilisations dans le traitement du cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001130A (en) 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
CZ290678B6 (cs) 2002-09-11
WO1999007711A1 (fr) 1999-02-18
NZ502657A (en) 2001-06-29
TW513435B (en) 2002-12-11
CA2300391A1 (fr) 1999-02-18
HUP0101311A1 (hu) 2001-09-28
NO20000605L (no) 2000-02-07
BG104151A (bg) 2000-10-31
JP2001512734A (ja) 2001-08-28
AU9068398A (en) 1999-03-01
HUP0101311A3 (en) 2002-10-28
CO4960665A1 (es) 2000-09-25
CN1267303A (zh) 2000-09-20
EP1003752A1 (fr) 2000-05-31
DE19734444A1 (de) 1999-02-11
US6355647B1 (en) 2002-03-12
ID24222A (id) 2000-07-13
NO20000605D0 (no) 2000-02-07
PL340726A1 (en) 2001-02-26
ZA987114B (en) 2000-02-07
HRP980435A2 (en) 1999-04-30
KR20010022658A (ko) 2001-03-26
TR200000371T2 (tr) 2000-11-21
AU749539B2 (en) 2002-06-27
IL134161A0 (en) 2001-04-30
BR9811091A (pt) 2000-09-12
CZ2000462A3 (cs) 2000-05-17
AR016594A1 (es) 2001-07-25

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