SI9620059A - Virusni vektorji in njihova uporaba za zdravljenje hiperproliferativnih motenj, zlasti restenoze - Google Patents

Virusni vektorji in njihova uporaba za zdravljenje hiperproliferativnih motenj, zlasti restenoze Download PDF

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Publication number: SI9620059A
Authority: SI; Slovenia
Prior art keywords: adenovirus; virus; gax; gene; virus according
Prior art date: 1995-03-31

Application number

SI9620059A

Other languages

English (en)

Slovenian (sl)

Inventor

Didier Branellec

Kenneth Walsh

Jeffrey M. Isner

Patrice Denefle

Original Assignee

Case Western Reserve University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-31

Filing date

1996-03-28

Publication date

1998-06-30

1996-03-28 Application filed by Case Western Reserve University filed Critical Case Western Reserve University

1998-06-30 Publication of SI9620059A publication Critical patent/SI9620059A/sl

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230000004044 response Effects 0.000 description 1
108090000064 retinoic acid receptors Proteins 0.000 description 1
102000003702 retinoic acid receptors Human genes 0.000 description 1
239000007320 rich medium Substances 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
210000002027 skeletal muscle Anatomy 0.000 description 1
241000894007 species Species 0.000 description 1
238000012453 sprague-dawley rat model Methods 0.000 description 1
238000007619 statistical method Methods 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
230000009469 supplementation Effects 0.000 description 1
230000001629 suppression Effects 0.000 description 1
238000011477 surgical intervention Methods 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
238000012360 testing method Methods 0.000 description 1
230000008719 thickening Effects 0.000 description 1
229940113082 thymine Drugs 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
238000013518 transcription Methods 0.000 description 1
230000035897 transcription Effects 0.000 description 1
230000002103 transcriptional effect Effects 0.000 description 1
230000009466 transformation Effects 0.000 description 1
230000001052 transient effect Effects 0.000 description 1
230000014616 translation Effects 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
241000712461 unidentified influenza virus Species 0.000 description 1
230000009750 upstream signaling Effects 0.000 description 1
230000006492 vascular dysfunction Effects 0.000 description 1
231100000216 vascular lesion Toxicity 0.000 description 1
230000006439 vascular pathology Effects 0.000 description 1
210000005048 vimentin Anatomy 0.000 description 1
230000029812 viral genome replication Effects 0.000 description 1
210000002845 virion Anatomy 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Zoology (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biotechnology (AREA)
Immunology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)

SI9620059A 1995-03-31 1996-03-28 Virusni vektorji in njihova uporaba za zdravljenje hiperproliferativnih motenj, zlasti restenoze SI9620059A (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9504234A FR2732357B1 (fr)	1995-03-31	1995-03-31	Vecteurs viraux et utilisation pour le traitement des desordres hyperproliferatifs, notamment de la restenose
PCT/US1996/004493 WO1996030385A1 (fr)	1995-03-31	1996-03-28	Vecteurs viraux et leur utilisation pour traiter des maladies hyperproliferatives, en particulier, la restenose

Publications (1)

Publication Number	Publication Date
SI9620059A true SI9620059A (sl)	1998-06-30

Family

ID=9477928

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9620059A SI9620059A (sl)	1995-03-31	1996-03-28	Virusni vektorji in njihova uporaba za zdravljenje hiperproliferativnih motenj, zlasti restenoze

Country Status (16)

Country	Link
US (2)	US5851521A (fr)
EP (1)	EP0817791A4 (fr)
JP (1)	JPH11503314A (fr)
KR (1)	KR19980703454A (fr)
CN (1)	CN1190402A (fr)
AP (1)	AP1011A (fr)
AU (1)	AU701345B2 (fr)
BR (1)	BR9608449A (fr)
CA (1)	CA2216878A1 (fr)
CZ (1)	CZ308897A3 (fr)
FR (1)	FR2732357B1 (fr)
HU (1)	HUP9801767A3 (fr)
OA (1)	OA10516A (fr)
SI (1)	SI9620059A (fr)
SK (1)	SK132797A3 (fr)
WO (1)	WO1996030385A1 (fr)

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US20080200408A1 (en) *	2005-09-30	2008-08-21	Mccormack Kenneth	Deletion mutants of tetrodotoxin-resistant sodium channel alpha subunit
US7972813B2 (en) *	2005-09-30	2011-07-05	Vertex Pharmaceuticals Incorporated	Tetrodotoxin-resistant sodium channel alpha subunit
PL1969003T3 (pl)	2005-12-14	2011-05-31	Herantis Pharma Plc	Zastosowanie białka czynnika neurotroficznego
WO2007089780A2 (fr) *	2006-01-30	2007-08-09	Licentia, Ltd.	Matériaux de thérapie gènique à tyrosine kinase bmx/etk et méthodes
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FI20070808A0 (fi)	2007-10-25	2007-10-25	Mart Saarma	GDNF:n silmukointivariantit ja niiden käytöt
JP5309159B2 (ja)	2008-01-09	2013-10-09	コングクユニバーシティインダストリアルコーオペレーションコーポレーション	バキュロウイルスを利用したワクチン
US20090196854A1 (en) *	2008-02-04	2009-08-06	Kytos Biosystems S.A.	Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery
FI20080326A0 (fi)	2008-04-30	2008-04-30	Licentia Oy	Neurotroofinen tekijä MANF ja sen käytöt
US8052970B2 (en) *	2008-06-30	2011-11-08	The Regents Of The University Of Michigan	Lysosomal phospholipase A2 (LPLA2) activity as a diagnostic and therapeutic target for identifying and treating systemic lupus erythematosis
EP2496268A4 (fr)	2009-11-06	2013-06-19	Univ Chung Ang Ind	Systèmes de délivrance de gènes à base de nanoparticules
KR101232123B1 (ko)	2010-10-08	2013-02-12	연세대학교 산학협력단	재조합된 유전자발현 조절서열을 가지는 종양 특이적 발현이 개선된 유전자 전달체
CA2840175C (fr)	2011-05-19	2021-11-16	The Regents Of The University Of Michigan	Agents se liant a l'integrine alpha-2 et leur utilisation pour inhiber la proliferation des cellules cancereuses
WO2013077645A1 (fr)	2011-11-24	2013-05-30	주식회사 바이로메드	Nouvelle lignée cellulaire produisant un adénovirus et son utilisation
US9365496B2 (en)	2011-11-30	2016-06-14	Ludwig Institute For Cancer Research	iNKT cell modulators and methods of using the same
GB201120860D0 (en)	2011-12-05	2012-01-18	Cambridge Entpr Ltd	Cancer immunotherapy
WO2013184209A1 (fr)	2012-06-04	2013-12-12	Ludwig Institute For Cancer Research Ltd.	Mif destiné à être utilisé dans des méthodes de traitement de sujets atteints d'une maladie neurodégénérative
DK3421602T3 (da)	2012-09-06	2021-05-10	Univ Chicago	Antisense polynucleotides to induce exon skipping and methods of treating dystrophies
KR101429696B1 (ko)	2012-11-21	2014-08-13	국립암센터	안전성 및 항암활성이 증가된 재조합 아데노바이러스 및 이의 용도
MY170528A (en)	2013-02-18	2019-08-09	Vegenics Pty Ltd	Vegfr-3 ligand binding molecules and uses thereof
WO2014191630A2 (fr)	2013-05-28	2014-12-04	Helsingin Yliopisto	Modèle animal non humain codant pour un gène manf non fonctionnel
CA2981960C (fr)	2015-04-08	2023-09-19	The University Of Chicago	Compositions et methodes de correction de la dystrophie musculaire des ceintures de type 2c par saut d'exon
WO2017065497A1 (fr)	2015-10-12	2017-04-20	한양대학교 산학협력단	Complexe d'adénovirus pour transfert génétique ou thérapie génique
AR109538A1 (es)	2016-09-20	2018-12-19	Boehringer Ingelheim Vetmedica Gmbh	Vacuna contra la gripe porcina
BR112019005511A2 (pt)	2016-09-20	2019-10-01	Boehringer Ingelheim Vetmedica Gmbh	vetores de adenovírus canino
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EA201990711A1 (ru)	2016-09-20	2019-09-30	Бёрингер Ингельхайм Ветмедика Гмбх	Новый ehv сайт инсерции orf70
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1995
- 1995-03-31 FR FR9504234A patent/FR2732357B1/fr not_active Expired - Fee Related
1996
- 1996-03-28 KR KR1019970706858A patent/KR19980703454A/ko not_active Ceased
- 1996-03-28 CZ CZ973088A patent/CZ308897A3/cs unknown
- 1996-03-28 WO PCT/US1996/004493 patent/WO1996030385A1/fr not_active Ceased
- 1996-03-28 EP EP96912530A patent/EP0817791A4/fr not_active Withdrawn
- 1996-03-28 SI SI9620059A patent/SI9620059A/sl not_active IP Right Cessation
- 1996-03-28 CA CA002216878A patent/CA2216878A1/fr not_active Abandoned
- 1996-03-28 AU AU55315/96A patent/AU701345B2/en not_active Ceased
- 1996-03-28 CN CN96193929A patent/CN1190402A/zh active Pending
- 1996-03-28 AP APAP/P/1997/001117A patent/AP1011A/en active
- 1996-03-28 HU HU9801767A patent/HUP9801767A3/hu unknown
- 1996-03-28 JP JP8529747A patent/JPH11503314A/ja not_active Ceased
- 1996-03-28 BR BR9608449-9A patent/BR9608449A/pt not_active Application Discontinuation
- 1996-03-28 SK SK1327-97A patent/SK132797A3/sk unknown
- 1996-09-30 US US08/723,726 patent/US5851521A/en not_active Ceased
1997
- 1997-09-29 OA OA70089A patent/OA10516A/en unknown
2000
- 2000-12-21 US US09/740,876 patent/USRE37933E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR19980703454A (ko)	1998-11-05
CA2216878A1 (fr)	1996-10-03
EP0817791A4 (fr)	1998-07-15
CN1190402A (zh)	1998-08-12
SK132797A3 (en)	1998-07-08
AU701345B2 (en)	1999-01-28
AU5531596A (en)	1996-10-16
HUP9801767A2 (hu)	1998-10-28
USRE37933E1 (en)	2002-12-10
JPH11503314A (ja)	1999-03-26
FR2732357B1 (fr)	1997-04-30
AP9701117A0 (en)	1996-03-28
OA10516A (en)	2002-04-22
EP0817791A1 (fr)	1998-01-14
HUP9801767A3 (en)	1999-04-28
BR9608449A (pt)	1999-11-30
AP1011A (en)	2001-09-22
FR2732357A1 (fr)	1996-10-04
CZ308897A3 (cs)	1998-03-18
US5851521A (en)	1998-12-22
WO1996030385A1 (fr)	1996-10-03
MX9707549A (es)	1998-07-31

Publication	Publication Date	Title
SI9620059A (sl)	1998-06-30	Virusni vektorji in njihova uporaba za zdravljenje hiperproliferativnih motenj, zlasti restenoze
PT1792997E (pt)	2012-02-02	Adn triplex lentiviral, vetores e células recombiantes contendo adn triplex lentiviral
PL186151B1 (pl)	2003-11-28	Zrekombinowane adenowirusy, kompozycje zawierające zrekombinowane adenowirusy, komórka gospodarza zainfekowana zrekombinowanym adenowirusem oraz sposób otrzymywania biologicznie aktywnego białka p53 typu dzikiego
JPH11511980A (ja)	1999-10-19	Ｍｄｍ２タンパク質の腫瘍原活性のアンタゴニスト及び癌治療におけるその使用
JP2001510028A (ja)	2001-07-31	ｐ２７およびその融合物で血管増殖性疾患を処置する方法
CN100357433C (zh)	2007-12-26	可用于基因治疗和治疗性筛选的eNOS突变
JP2005504010A (ja)	2005-02-10	成長ホルモンおよびｆｏｘｍ１ｂを用いた肝臓疾患および肝臓損傷の処置方法
EP1115877B1 (fr)	2009-01-14	Produits de recombinaison polynucleotidiques et leurs utilisations
EP1307582B1 (fr)	2008-05-28	Produits de recombinaison d'acide nucleique, cellules vasculaires transformees au moyen de ces produits de recombinaison, compositions pharmaceutiques et procedes les mettant en application afin d'induire l'angiogenese
JPH11514881A (ja)	1999-12-21	Ｇａｘタンパク質の癌治療への応用
JPH11506325A (ja)	1999-06-08	Δｐ６２、その変異体、核酸配列及びこれらの使用
MXPA97007549A (en)	1998-11-09	Viral vectors and their use to treat disordershiperproliferativos, in particular resteno
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