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SI3002009T1 - Zdravljenje kronične mieloične levkemije, ki je odporna na imatinib, ki ima mutacijo 1457t>c na genu bcrabl, s pomočjo sestavine bosutinib - Google Patents

Zdravljenje kronične mieloične levkemije, ki je odporna na imatinib, ki ima mutacijo 1457t>c na genu bcrabl, s pomočjo sestavine bosutinib

Info

Publication number
SI3002009T1
SI3002009T1 SI200832178T SI200832178T SI3002009T1 SI 3002009 T1 SI3002009 T1 SI 3002009T1 SI 200832178 T SI200832178 T SI 200832178T SI 200832178 T SI200832178 T SI 200832178T SI 3002009 T1 SI3002009 T1 SI 3002009T1
Authority
SI
Slovenia
Prior art keywords
mutaton
bosutinib
compound
treatment
myelogenous leukemia
Prior art date
Application number
SI200832178T
Other languages
English (en)
Inventor
Becker Hewes
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3002009(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of SI3002009T1 publication Critical patent/SI3002009T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI200832178T 2007-06-01 2008-05-30 Zdravljenje kronične mieloične levkemije, ki je odporna na imatinib, ki ima mutacijo 1457t>c na genu bcrabl, s pomočjo sestavine bosutinib SI3002009T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93265007P 2007-06-01 2007-06-01
EP15191756.4A EP3002009B1 (en) 2007-06-01 2008-05-30 Treatment of imatinib resistant chronic myelogenous leukemia having the mutaton 1457t>c in the bcrabl gene using the compound bosutinib

Publications (1)

Publication Number Publication Date
SI3002009T1 true SI3002009T1 (sl) 2021-09-30

Family

ID=39639071

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200832178T SI3002009T1 (sl) 2007-06-01 2008-05-30 Zdravljenje kronične mieloične levkemije, ki je odporna na imatinib, ki ima mutacijo 1457t>c na genu bcrabl, s pomočjo sestavine bosutinib
SI200831212T SI2478905T1 (sl) 2007-06-01 2008-05-30 Zdravljenje levkemije, rezistentne na imatinib, z uporabo 4-aminokinolin-3-karbonitrilov

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200831212T SI2478905T1 (sl) 2007-06-01 2008-05-30 Zdravljenje levkemije, rezistentne na imatinib, z uporabo 4-aminokinolin-3-karbonitrilov

Country Status (23)

Country Link
US (1) US11103497B2 (sl)
EP (4) EP3002009B1 (sl)
JP (3) JP5888853B2 (sl)
KR (1) KR101493543B1 (sl)
CN (1) CN101686973B (sl)
AU (1) AU2008260070B9 (sl)
BR (1) BRPI0812355A2 (sl)
CA (3) CA2964162C (sl)
CL (1) CL2008001577A1 (sl)
CY (2) CY1115251T1 (sl)
DK (2) DK3002009T3 (sl)
ES (2) ES2477567T3 (sl)
HU (1) HUE055524T2 (sl)
IL (1) IL202407A0 (sl)
MX (1) MX2009013069A (sl)
PA (1) PA8782301A1 (sl)
PL (2) PL3002009T3 (sl)
PT (2) PT3002009T (sl)
RU (1) RU2464026C2 (sl)
SI (2) SI3002009T1 (sl)
TW (1) TW200908982A (sl)
WO (1) WO2008150957A2 (sl)
ZA (1) ZA200908480B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2964162C (en) 2007-06-01 2019-12-31 Wyeth Llc Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles having mutation in the bcrabl gene
CA2829131C (en) 2011-03-04 2018-11-20 Glaxosmithkline Intellectual Property (No.2) Limited Amino-quinolines as kinase inhibitors
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
AR092529A1 (es) 2012-09-13 2015-04-22 Glaxosmithkline Llc Compuesto de aminoquinazolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
TW201425307A (zh) 2012-09-13 2014-07-01 Glaxosmithkline Llc 作為激酶抑制劑之胺基-喹啉類
RU2662810C2 (ru) 2013-02-21 2018-07-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Хиназолины в качестве ингибиторов киназы
KR101733665B1 (ko) 2015-05-06 2017-05-10 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 진세노사이드 F1 또는 Rg3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
EP4017492A4 (en) * 2019-08-22 2023-10-11 Biohaven Therapeutics Ltd. MOLECULES THAT BIND TDP-43 FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED DISORDERS
CN115944636A (zh) * 2022-11-01 2023-04-11 华南师范大学 博舒替尼在抑制i-motif结构上的应用
WO2025024311A2 (en) * 2023-07-21 2025-01-30 Icahn School Of Medicine At Mount Sinai G9a/glp inhibitors and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) * 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
MXPA03006412A (es) * 2001-01-25 2003-10-15 Bristol Myers Squibb Co Metodos para administrar analogos de epotilona para tratamiento de cancer.
EP2343365A1 (en) 2001-10-05 2011-07-13 Novartis AG Mutated Abl kinase domains
TWI275390B (en) * 2002-04-30 2007-03-11 Wyeth Corp Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) * 2003-07-09 2005-01-13 Kane John Richard Method and apparatus for providing access to personal information
US7417148B2 (en) * 2003-11-06 2008-08-26 Wyeth 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
NL1031674C2 (nl) 2005-04-25 2007-04-26 Pfizer Antilichamen tegen myostatine.
MX2007014327A (es) * 2005-05-16 2008-02-11 Irm Llc Derivados de pirrolopiridina como inhibidores de cinasa de proteina.
US20090163510A1 (en) 2005-07-15 2009-06-25 Bristol-Myers Squibb Company Methods of Identifying and Treating Individuals Exhibiting Mutant SRC Kinase Polypeptides
EA015589B1 (ru) 2005-10-06 2011-10-31 Эли Лилли Энд Компани Антитела против миостатина и их применение
US20100029676A1 (en) * 2005-11-04 2010-02-04 Sawyers Charles L T315a and f317i mutations of bcr-abl kinase domain
CA2964162C (en) 2007-06-01 2019-12-31 Wyeth Llc Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles having mutation in the bcrabl gene

Also Published As

Publication number Publication date
HUE055524T2 (hu) 2021-11-29
PT2478905E (pt) 2014-07-16
CY1115251T1 (el) 2017-01-04
CA2964162C (en) 2019-12-31
IL202407A0 (en) 2010-06-30
PL3002009T3 (pl) 2021-12-13
AU2008260070B9 (en) 2012-01-19
PA8782301A1 (es) 2009-01-23
CA2688467A1 (en) 2008-12-11
CY1124391T1 (el) 2022-07-22
DK3002009T3 (da) 2021-08-02
ES2881391T3 (es) 2021-11-29
EP2777704A2 (en) 2014-09-17
HK1142812A1 (en) 2010-12-17
US11103497B2 (en) 2021-08-31
DK2478905T3 (da) 2014-06-30
RU2464026C2 (ru) 2012-10-20
CA2868899C (en) 2017-06-13
EP3002009A2 (en) 2016-04-06
RU2009144128A (ru) 2011-07-20
CA2868899A1 (en) 2008-12-11
JP5888853B2 (ja) 2016-03-22
EP3002009B1 (en) 2021-07-07
US20080318971A1 (en) 2008-12-25
CL2008001577A1 (es) 2008-07-25
CA2688467C (en) 2015-05-12
BRPI0812355A2 (pt) 2015-01-27
EP3002009A3 (en) 2016-07-06
EP2478905B1 (en) 2014-05-14
WO2008150957A3 (en) 2009-08-06
CN101686973B (zh) 2013-06-19
AU2008260070B2 (en) 2011-08-18
JP2010529038A (ja) 2010-08-26
CN101686973A (zh) 2010-03-31
EP2152267A2 (en) 2010-02-17
CA2964162A1 (en) 2008-12-11
PT3002009T (pt) 2021-08-02
ZA200908480B (en) 2010-08-25
TW200908982A (en) 2009-03-01
WO2008150957A2 (en) 2008-12-11
SI2478905T1 (sl) 2014-07-31
MX2009013069A (es) 2010-03-17
EP2478905A2 (en) 2012-07-25
EP2777704A3 (en) 2015-01-21
JP2016074700A (ja) 2016-05-12
PL2478905T3 (pl) 2014-10-31
KR20100017983A (ko) 2010-02-16
JP2014111629A (ja) 2014-06-19
AU2008260070A1 (en) 2008-12-11
EP2478905A3 (en) 2013-01-16
ES2477567T3 (es) 2014-07-17
KR101493543B1 (ko) 2015-02-13

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