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BRPI0812355A2 - Tratamento de leucemia resistente a imatinib - Google Patents

Tratamento de leucemia resistente a imatinib

Info

Publication number
BRPI0812355A2
BRPI0812355A2 BRPI0812355-1A2A BRPI0812355A BRPI0812355A2 BR PI0812355 A2 BRPI0812355 A2 BR PI0812355A2 BR PI0812355 A BRPI0812355 A BR PI0812355A BR PI0812355 A2 BRPI0812355 A2 BR PI0812355A2
Authority
BR
Brazil
Prior art keywords
imatinib
resistant leukemia
leukemia treatment
treatment
resistant
Prior art date
Application number
BRPI0812355-1A2A
Other languages
English (en)
Inventor
Becker Hewes
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0812355(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of BRPI0812355A2 publication Critical patent/BRPI0812355A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0812355-1A2A 2007-06-01 2008-05-30 Tratamento de leucemia resistente a imatinib BRPI0812355A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93265007P 2007-06-01 2007-06-01
PCT/US2008/065215 WO2008150957A2 (en) 2007-06-01 2008-05-30 Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

Publications (1)

Publication Number Publication Date
BRPI0812355A2 true BRPI0812355A2 (pt) 2015-01-27

Family

ID=39639071

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812355-1A2A BRPI0812355A2 (pt) 2007-06-01 2008-05-30 Tratamento de leucemia resistente a imatinib

Country Status (23)

Country Link
US (1) US11103497B2 (pt)
EP (4) EP2478905B1 (pt)
JP (3) JP5888853B2 (pt)
KR (1) KR101493543B1 (pt)
CN (1) CN101686973B (pt)
AU (1) AU2008260070B9 (pt)
BR (1) BRPI0812355A2 (pt)
CA (3) CA2688467C (pt)
CL (1) CL2008001577A1 (pt)
CY (2) CY1115251T1 (pt)
DK (2) DK2478905T3 (pt)
ES (2) ES2477567T3 (pt)
HU (1) HUE055524T2 (pt)
IL (1) IL202407A0 (pt)
MX (1) MX2009013069A (pt)
PA (1) PA8782301A1 (pt)
PL (2) PL3002009T3 (pt)
PT (2) PT2478905E (pt)
RU (1) RU2464026C2 (pt)
SI (2) SI2478905T1 (pt)
TW (1) TW200908982A (pt)
WO (1) WO2008150957A2 (pt)
ZA (1) ZA200908480B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2478905B1 (en) 2007-06-01 2014-05-14 Wyeth LLC Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles
EA023998B1 (ru) 2011-03-04 2016-08-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Аминохинолины в качестве ингибиторов киназ
TWI547494B (zh) 2011-08-18 2016-09-01 葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之胺基喹唑啉類
AR092530A1 (es) 2012-09-13 2015-04-22 Glaxosmithkline Llc Compuesto de amino-quinolina, composicion farmaceutica que lo comprende y uso de dicho compuesto para la preparacion de un medicamento
TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
JP6301374B2 (ja) 2013-02-21 2018-03-28 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited キナーゼ阻害剤としてのキナゾリン類
KR101733665B1 (ko) 2015-05-06 2017-05-10 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 진세노사이드 F1 또는 Rg3을 유효성분으로 포함하는 글리벡 내성 백혈병 예방 또는 치료용 약학 조성물
AU2020332367A1 (en) * 2019-08-22 2022-02-17 Biohaven Therapeutics Ltd. Molecules that bind to TDP-43 for the treatment of amyotrophic lateral sclerosis and related disorders
CN115944636A (zh) * 2022-11-01 2023-04-11 华南师范大学 博舒替尼在抑制i-motif结构上的应用
WO2025024311A2 (en) * 2023-07-21 2025-01-30 Icahn School Of Medicine At Mount Sinai G9a/glp inhibitors and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
IL156578A0 (en) * 2001-01-25 2004-01-04 Bristol Myers Squibb Co A method for formulating an epothilone analog for pharmaceutical use and pharmaceutical preparations including an epothilone analog
PT2017335E (pt) 2001-10-05 2011-03-02 Novartis Ag Domínios da cinase abl mutados
TWI275390B (en) * 2002-04-30 2007-03-11 Wyeth Corp Process for the preparation of 7-substituted-3- quinolinecarbonitriles
US20050010780A1 (en) * 2003-07-09 2005-01-13 Kane John Richard Method and apparatus for providing access to personal information
RU2006113691A (ru) 2003-11-06 2007-12-20 Вайет (Us) Применение 4-анилин-3-хинолинкарбонитрилов для лечения хронической миелогенной лейкемии (cml)
AU2006239860B2 (en) 2005-04-25 2012-01-19 Amgen Fremont Inc. Antibodies to myostatin
CN101218241B (zh) * 2005-05-16 2011-02-16 Irm责任有限公司 用作蛋白激酶抑制剂的吡咯并吡啶衍生物
EP1904654A2 (en) 2005-07-15 2008-04-02 Brystol-Myers Squibb Company Methods of identifying and treating individuals exhibiting mutant src kinase polypeptides
ES2533464T3 (es) 2005-10-06 2015-04-10 Eli Lilly And Company Anticuerpos anti-miostatina
US20100029676A1 (en) * 2005-11-04 2010-02-04 Sawyers Charles L T315a and f317i mutations of bcr-abl kinase domain
EP2478905B1 (en) 2007-06-01 2014-05-14 Wyeth LLC Treatment of imatinib resistant leukemia using 4-aminoquinoline-3-carbonitriles

Also Published As

Publication number Publication date
SI3002009T1 (sl) 2021-09-30
AU2008260070B9 (en) 2012-01-19
CA2868899C (en) 2017-06-13
CA2868899A1 (en) 2008-12-11
EP3002009A2 (en) 2016-04-06
CN101686973A (zh) 2010-03-31
RU2009144128A (ru) 2011-07-20
CN101686973B (zh) 2013-06-19
IL202407A0 (en) 2010-06-30
HUE055524T2 (hu) 2021-11-29
PT3002009T (pt) 2021-08-02
JP2014111629A (ja) 2014-06-19
ES2881391T3 (es) 2021-11-29
HK1142812A1 (en) 2010-12-17
EP2777704A2 (en) 2014-09-17
CA2688467C (en) 2015-05-12
DK3002009T3 (da) 2021-08-02
US20080318971A1 (en) 2008-12-25
PA8782301A1 (es) 2009-01-23
PT2478905E (pt) 2014-07-16
DK2478905T3 (da) 2014-06-30
CY1124391T1 (el) 2022-07-22
SI2478905T1 (sl) 2014-07-31
EP3002009A3 (en) 2016-07-06
EP2478905B1 (en) 2014-05-14
WO2008150957A3 (en) 2009-08-06
CA2688467A1 (en) 2008-12-11
US11103497B2 (en) 2021-08-31
CY1115251T1 (el) 2017-01-04
KR101493543B1 (ko) 2015-02-13
EP2152267A2 (en) 2010-02-17
RU2464026C2 (ru) 2012-10-20
EP2777704A3 (en) 2015-01-21
AU2008260070A1 (en) 2008-12-11
WO2008150957A2 (en) 2008-12-11
EP2478905A3 (en) 2013-01-16
TW200908982A (en) 2009-03-01
ES2477567T3 (es) 2014-07-17
CA2964162C (en) 2019-12-31
PL3002009T3 (pl) 2021-12-13
EP2478905A2 (en) 2012-07-25
PL2478905T3 (pl) 2014-10-31
EP3002009B1 (en) 2021-07-07
AU2008260070B2 (en) 2011-08-18
JP2016074700A (ja) 2016-05-12
JP2010529038A (ja) 2010-08-26
CA2964162A1 (en) 2008-12-11
CL2008001577A1 (es) 2008-07-25
ZA200908480B (en) 2010-08-25
MX2009013069A (es) 2010-03-17
KR20100017983A (ko) 2010-02-16
JP5888853B2 (ja) 2016-03-22

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL