SI2751092T1 - Selektivni in reverzibilni inhibitorji proteaze 7, specifične za ubikvitin - Google Patents

Selektivni in reverzibilni inhibitorji proteaze 7, specifične za ubikvitin

Info

Publication number: SI2751092T1
Authority: SI; Slovenia
Prior art keywords: selective; specific protease; reversible inhibitors; ubiquitin specific; ubiquitin
Prior art date: 2011-09-02

Application number

SI201230714A

Other languages

English (en)

Inventor

Frederic Colland

Marie-Edith Gourdel

Original Assignee

Hybrigenics S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-09-02

Filing date

2012-08-29

Publication date

2016-10-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46750347&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2751092(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2012-08-29 Application filed by Hybrigenics S.A. filed Critical Hybrigenics S.A.

2016-10-28 Publication of SI2751092T1 publication Critical patent/SI2751092T1/sl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Virology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Immunology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Hematology (AREA)
Obesity (AREA)
Molecular Biology (AREA)
Psychology (AREA)
Biotechnology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SI201230714A 2011-09-02 2012-08-29 Selektivni in reverzibilni inhibitorji proteaze 7, specifične za ubikvitin SI2751092T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP11306096A EP2565186A1 (en)	2011-09-02	2011-09-02	Selective and reversible inhibitors of ubiquitin specific protease 7
PCT/EP2012/066741 WO2013030218A1 (en)	2011-09-02	2012-08-29	Selective and reversible inhibitors of ubiquitin specific protease 7
EP12751080.8A EP2751092B1 (en)	2011-09-02	2012-08-29	Selective and reversible inhibitors of ubiquitin specific protease 7

Publications (1)

Publication Number	Publication Date
SI2751092T1 true SI2751092T1 (sl)	2016-10-28

Family

ID=46750347

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201230714A SI2751092T1 (sl)	2011-09-02	2012-08-29	Selektivni in reverzibilni inhibitorji proteaze 7, specifične za ubikvitin

Country Status (24)

Country	Link
US (1)	US9546150B2 (sl)
EP (2)	EP2565186A1 (sl)
JP (1)	JP6059228B2 (sl)
KR (1)	KR20140085430A (sl)
CN (1)	CN103930415B (sl)
AR (1)	AR087757A1 (sl)
AU (1)	AU2012300944B2 (sl)
BR (1)	BR112014004649A2 (sl)
CA (1)	CA2847017A1 (sl)
CL (1)	CL2014000511A1 (sl)
DK (1)	DK2751092T3 (sl)
ES (1)	ES2594603T3 (sl)
HU (1)	HUE029418T2 (sl)
IL (1)	IL231203A (sl)
LT (1)	LT2751092T (sl)
MA (1)	MA35361B1 (sl)
MX (1)	MX340500B (sl)
PL (1)	PL2751092T3 (sl)
PT (1)	PT2751092T (sl)
RU (1)	RU2622640C2 (sl)
SG (1)	SG11201400205QA (sl)
SI (1)	SI2751092T1 (sl)
TN (1)	TN2014000079A1 (sl)
WO (1)	WO2013030218A1 (sl)

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GB201708652D0 (en)	2017-05-31	2017-07-12	Mission Therapeutics Ltd	Novel compounds and uses
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EP4157332A4 (en) *	2020-05-26	2024-06-05	Lowell Therapeutics, Inc.	METHODS OF TREATING VIRAL INFECTION USING PROTEASE INHIBITORS
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JP2011530596A (ja)	2008-08-11	2011-12-22	プレジデントアンドフェロウズオブハーバードカレッジ	ｔＲＮＡ合成酵素の阻害のためのハロフジノン類似体およびそれらの使用
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US20110177105A1 (en)	2010-01-15	2011-07-21	Roman Lopez	Novel Selective Inhibitors of Ubiquitin Specific Protease 7, the Pharmaceutical Compositions Thereof and Their Therapeutic Applications
EP2565186A1 (en) *	2011-09-02	2013-03-06	Hybrigenics S.A.	Selective and reversible inhibitors of ubiquitin specific protease 7

2011
- 2011-09-02 EP EP11306096A patent/EP2565186A1/en not_active Withdrawn
2012
- 2012-08-29 RU RU2014112692A patent/RU2622640C2/ru not_active IP Right Cessation
- 2012-08-29 CA CA2847017A patent/CA2847017A1/en not_active Abandoned
- 2012-08-29 HU HUE12751080A patent/HUE029418T2/en unknown
- 2012-08-29 SG SG11201400205QA patent/SG11201400205QA/en unknown
- 2012-08-29 LT LTEP12751080.8T patent/LT2751092T/lt unknown
- 2012-08-29 AU AU2012300944A patent/AU2012300944B2/en not_active Ceased
- 2012-08-29 JP JP2014527641A patent/JP6059228B2/ja not_active Expired - Fee Related
- 2012-08-29 SI SI201230714A patent/SI2751092T1/sl unknown
- 2012-08-29 CN CN201280054148.2A patent/CN103930415B/zh not_active Expired - Fee Related
- 2012-08-29 ES ES12751080.8T patent/ES2594603T3/es active Active
- 2012-08-29 EP EP12751080.8A patent/EP2751092B1/en active Active
- 2012-08-29 US US14/241,923 patent/US9546150B2/en not_active Expired - Fee Related
- 2012-08-29 PT PT127510808T patent/PT2751092T/pt unknown
- 2012-08-29 BR BR112014004649A patent/BR112014004649A2/pt not_active Application Discontinuation
- 2012-08-29 KR KR1020147007456A patent/KR20140085430A/ko not_active Ceased
- 2012-08-29 WO PCT/EP2012/066741 patent/WO2013030218A1/en not_active Ceased
- 2012-08-29 MX MX2014002489A patent/MX340500B/es active IP Right Grant
- 2012-08-29 DK DK12751080.8T patent/DK2751092T3/en active
- 2012-08-29 PL PL12751080T patent/PL2751092T3/pl unknown
- 2012-08-31 AR ARP120103228A patent/AR087757A1/es not_active Application Discontinuation
2014
- 2014-02-21 TN TNP2014000079A patent/TN2014000079A1/en unknown
- 2014-02-25 MA MA36781A patent/MA35361B1/fr unknown
- 2014-02-27 IL IL231203A patent/IL231203A/en active IP Right Grant
- 2014-02-28 CL CL2014000511A patent/CL2014000511A1/es unknown

Also Published As

Publication number	Publication date
DK2751092T3 (en)	2016-10-10
NZ621827A (en)	2016-07-29
HUE029418T2 (en)	2017-02-28
US20140371247A1 (en)	2014-12-18
MX340500B (es)	2016-07-11
ES2594603T3 (es)	2016-12-21
PL2751092T3 (pl)	2017-01-31
IL231203A0 (en)	2014-04-30
IL231203A (en)	2017-04-30
RU2622640C2 (ru)	2017-06-19
MX2014002489A (es)	2014-11-14
CN103930415A (zh)	2014-07-16
PT2751092T (pt)	2016-11-04
JP6059228B2 (ja)	2017-01-11
SG11201400205QA (en)	2014-03-28
MA35361B1 (fr)	2014-08-01
AU2012300944A1 (en)	2014-03-20
AU2012300944B2 (en)	2017-06-01
BR112014004649A2 (pt)	2017-03-14
CL2014000511A1 (es)	2014-12-05
KR20140085430A (ko)	2014-07-07
AR087757A1 (es)	2014-04-16
EP2565186A1 (en)	2013-03-06
JP2014527064A (ja)	2014-10-09
LT2751092T (lt)	2016-10-25
WO2013030218A1 (en)	2013-03-07
EP2751092A1 (en)	2014-07-09
CA2847017A1 (en)	2013-03-07
TN2014000079A1 (en)	2015-07-01
US9546150B2 (en)	2017-01-17
WO2013030218A4 (en)	2013-04-25
RU2014112692A (ru)	2015-10-10
CN103930415B (zh)	2017-05-24
EP2751092B1 (en)	2016-07-27

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