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SI2059518T1 - Soli benzimidazolil piridil etrov in njihove formulacije - Google Patents

Soli benzimidazolil piridil etrov in njihove formulacije

Info

Publication number
SI2059518T1
SI2059518T1 SI200730587T SI200730587T SI2059518T1 SI 2059518 T1 SI2059518 T1 SI 2059518T1 SI 200730587 T SI200730587 T SI 200730587T SI 200730587 T SI200730587 T SI 200730587T SI 2059518 T1 SI2059518 T1 SI 2059518T1
Authority
SI
Slovenia
Prior art keywords
salts
formulations
pyridyl ethers
benzimidazolyl pyridyl
benzimidazolyl
Prior art date
Application number
SI200730587T
Other languages
English (en)
Inventor
Rampurna Gullapalli
Ahmad Hashash
Piotr H Karpinski
Kangwen L Lin
Eric M Loeser
Augustus O Okhamafe
Paul Allen Sutton
Eduardo Sy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI2059518T1 publication Critical patent/SI2059518T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
SI200730587T 2006-08-30 2007-08-30 Soli benzimidazolil piridil etrov in njihove formulacije SI2059518T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84117706P 2006-08-30 2006-08-30
US95446607P 2007-08-07 2007-08-07
EP07837588A EP2059518B1 (en) 2006-08-30 2007-08-30 Salts of benzimidazolyl pyridyl ethers and formulations thereof
PCT/US2007/019152 WO2008027523A2 (en) 2006-08-30 2007-08-30 Salts of benzimidazolyl pyridyl ethers and formulations thereof

Publications (1)

Publication Number Publication Date
SI2059518T1 true SI2059518T1 (sl) 2011-06-30

Family

ID=39027583

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200730587T SI2059518T1 (sl) 2006-08-30 2007-08-30 Soli benzimidazolil piridil etrov in njihove formulacije

Country Status (33)

Country Link
US (2) US8202998B2 (sl)
EP (1) EP2059518B1 (sl)
JP (1) JP5279712B2 (sl)
KR (1) KR20090043542A (sl)
CN (1) CN101516870B (sl)
AT (1) ATE504584T1 (sl)
AU (1) AU2007290388B2 (sl)
BR (1) BRPI0716243A2 (sl)
CA (1) CA2660376C (sl)
CL (1) CL2007002533A1 (sl)
CO (1) CO6150180A2 (sl)
CY (1) CY1112187T1 (sl)
DE (1) DE602007013774D1 (sl)
DK (1) DK2059518T3 (sl)
ES (1) ES2360968T3 (sl)
GT (1) GT200900045A (sl)
HR (1) HRP20110311T1 (sl)
IL (1) IL196811A (sl)
JO (1) JO2702B1 (sl)
MA (1) MA30711B1 (sl)
MX (1) MX2009002279A (sl)
MY (1) MY161829A (sl)
NO (1) NO20091236L (sl)
NZ (1) NZ574620A (sl)
PE (2) PE20130814A1 (sl)
PL (1) PL2059518T3 (sl)
PT (1) PT2059518E (sl)
RU (1) RU2457206C2 (sl)
SI (1) SI2059518T1 (sl)
TN (1) TN2009000068A1 (sl)
TW (1) TW200819438A (sl)
WO (1) WO2008027523A2 (sl)
ZA (1) ZA200900664B (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20130814A1 (es) * 2006-08-30 2013-08-08 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen
BRPI0808526A2 (pt) * 2007-03-02 2014-08-19 Novartis Ag Formas sólidas de um inibidor de raf cinase
JP2011524362A (ja) * 2008-06-13 2011-09-01 ノバルティス アーゲー 神経線維腫症用の置換ベンゾイミダゾール
TW201031406A (en) * 2009-01-29 2010-09-01 Novartis Ag Substituted benzimidazoles for the treatment of astrocytomas
WO2011044072A1 (en) 2009-10-05 2011-04-14 Novartis Ag Combination of raf-265 and an activator of ampk for use in the treatment of a proliferative disease
EP2645999A2 (en) * 2010-12-03 2013-10-09 Novartis AG Pharmaceutical compositions
CN114727963B (zh) * 2019-12-02 2024-12-27 阿斯利康(瑞典)有限公司 6-(2-氯-6-甲基吡啶-4-基)-5-(4-氟苯基)-1,2,4-三嗪-3-胺的固体药物配制品
CN114478519B (zh) * 2020-10-23 2024-06-11 励缔(杭州)医药科技有限公司 吡唑并吡啶类化合物或其盐及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1499311T3 (da) * 2002-03-29 2010-03-08 Novartis Vaccines & Diagnostic Substituerede benzaboler og anvendelse deraf som RAF-kinaseinhibitorer
US8299108B2 (en) * 2002-03-29 2012-10-30 Novartis Ag Substituted benzazoles and methods of their use as inhibitors of raf kinase
US20060189619A1 (en) 2005-02-24 2006-08-24 Wyeth 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds
TW200804345A (en) * 2005-08-30 2008-01-16 Novartis Ag Substituted benzimidazoles and methods of preparation
US7731795B2 (en) 2005-12-02 2010-06-08 Clemson University Rhombohedral fluoroberyllium borate crystals and hydrothermal growth thereof for use in laser and non-linear optical applications and devices
JP2009544617A (ja) * 2006-07-21 2009-12-17 ノバルティス アクチエンゲゼルシャフト ベンゾイミダゾリルピリジルエーテルの製剤
PE20130814A1 (es) 2006-08-30 2013-08-08 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen

Also Published As

Publication number Publication date
DK2059518T3 (da) 2011-05-16
TN2009000068A1 (en) 2010-08-19
ZA200900664B (en) 2009-12-30
US20100168060A1 (en) 2010-07-01
WO2008027523A3 (en) 2008-04-10
PL2059518T3 (pl) 2011-09-30
CL2007002533A1 (es) 2008-02-08
DE602007013774D1 (de) 2011-05-19
MY161829A (en) 2017-05-15
JP2010502622A (ja) 2010-01-28
EP2059518A2 (en) 2009-05-20
PE20130814A1 (es) 2013-08-08
WO2008027523A2 (en) 2008-03-06
CN101516870A (zh) 2009-08-26
CA2660376C (en) 2014-04-15
CN101516870B (zh) 2013-09-11
GT200900045A (es) 2010-06-14
US8202998B2 (en) 2012-06-19
BRPI0716243A2 (pt) 2013-09-03
ES2360968T3 (es) 2011-06-10
ATE504584T1 (de) 2011-04-15
AU2007290388A1 (en) 2008-03-06
CA2660376A1 (en) 2008-03-06
PT2059518E (pt) 2011-07-11
NO20091236L (no) 2009-03-27
TW200819438A (en) 2008-05-01
PE20080766A1 (es) 2008-06-15
RU2457206C2 (ru) 2012-07-27
HRP20110311T1 (hr) 2011-08-31
CO6150180A2 (es) 2010-04-20
JP5279712B2 (ja) 2013-09-04
MA30711B1 (fr) 2009-09-01
NZ574620A (en) 2011-05-27
US20120308651A1 (en) 2012-12-06
MX2009002279A (es) 2009-03-20
EP2059518B1 (en) 2011-04-06
CY1112187T1 (el) 2015-12-09
KR20090043542A (ko) 2009-05-06
HK1131613A1 (en) 2010-01-29
RU2009111384A (ru) 2010-10-10
IL196811A (en) 2013-03-24
AU2007290388B2 (en) 2011-07-14
JO2702B1 (en) 2013-03-03
IL196811A0 (en) 2009-11-18
US8501785B2 (en) 2013-08-06

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