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PL2059518T3 - Sole eterów benzimidazolilopirydylowych i ich preparaty - Google Patents

Sole eterów benzimidazolilopirydylowych i ich preparaty

Info

Publication number
PL2059518T3
PL2059518T3 PL07837588T PL07837588T PL2059518T3 PL 2059518 T3 PL2059518 T3 PL 2059518T3 PL 07837588 T PL07837588 T PL 07837588T PL 07837588 T PL07837588 T PL 07837588T PL 2059518 T3 PL2059518 T3 PL 2059518T3
Authority
PL
Poland
Prior art keywords
salts
formulations
pyridyl ethers
benzimidazolyl pyridyl
benzimidazolyl
Prior art date
Application number
PL07837588T
Other languages
English (en)
Inventor
Rampurna Gullapalli
Ahmad Hashash
Piotr H Karpinski
Kangwen L Lin
Eric M Loeser
Augustus O Okhamafe
Paul Allen Sutton
Eduardo Sy
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2059518T3 publication Critical patent/PL2059518T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL07837588T 2006-08-30 2007-08-30 Sole eterów benzimidazolilopirydylowych i ich preparaty PL2059518T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84117706P 2006-08-30 2006-08-30
US95446607P 2007-08-07 2007-08-07
EP07837588A EP2059518B1 (en) 2006-08-30 2007-08-30 Salts of benzimidazolyl pyridyl ethers and formulations thereof
PCT/US2007/019152 WO2008027523A2 (en) 2006-08-30 2007-08-30 Salts of benzimidazolyl pyridyl ethers and formulations thereof

Publications (1)

Publication Number Publication Date
PL2059518T3 true PL2059518T3 (pl) 2011-09-30

Family

ID=39027583

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07837588T PL2059518T3 (pl) 2006-08-30 2007-08-30 Sole eterów benzimidazolilopirydylowych i ich preparaty

Country Status (33)

Country Link
US (2) US8202998B2 (pl)
EP (1) EP2059518B1 (pl)
JP (1) JP5279712B2 (pl)
KR (1) KR20090043542A (pl)
CN (1) CN101516870B (pl)
AT (1) ATE504584T1 (pl)
AU (1) AU2007290388B2 (pl)
BR (1) BRPI0716243A2 (pl)
CA (1) CA2660376C (pl)
CL (1) CL2007002533A1 (pl)
CO (1) CO6150180A2 (pl)
CY (1) CY1112187T1 (pl)
DE (1) DE602007013774D1 (pl)
DK (1) DK2059518T3 (pl)
ES (1) ES2360968T3 (pl)
GT (1) GT200900045A (pl)
HR (1) HRP20110311T1 (pl)
IL (1) IL196811A (pl)
JO (1) JO2702B1 (pl)
MA (1) MA30711B1 (pl)
MX (1) MX2009002279A (pl)
MY (1) MY161829A (pl)
NO (1) NO20091236L (pl)
NZ (1) NZ574620A (pl)
PE (2) PE20080766A1 (pl)
PL (1) PL2059518T3 (pl)
PT (1) PT2059518E (pl)
RU (1) RU2457206C2 (pl)
SI (1) SI2059518T1 (pl)
TN (1) TN2009000068A1 (pl)
TW (1) TW200819438A (pl)
WO (1) WO2008027523A2 (pl)
ZA (1) ZA200900664B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080766A1 (es) * 2006-08-30 2008-06-15 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen
WO2008140850A1 (en) * 2007-03-02 2008-11-20 Novartis Ag Solid forms of a raf kinase inhibitor
AU2009257487B2 (en) * 2008-06-13 2013-01-31 Novartis Ag Substituted benzimidazoles for neurofibromatosis
DK2391366T3 (da) * 2009-01-29 2013-01-07 Novartis Ag Substituerede benzimidazoler til behandling af astrocytomer
WO2011044072A1 (en) 2009-10-05 2011-04-14 Novartis Ag Combination of raf-265 and an activator of ampk for use in the treatment of a proliferative disease
PH12013501098A1 (en) * 2010-12-03 2013-07-08 Novartis Ag Pharmaceutical compositions
WO2021110697A1 (en) * 2019-12-02 2021-06-10 Astrazeneca Ab Solid pharmaceutical formulations of 6-(2-chloro-6-methylpyridin-4-yl)-5-(-4-fluorophenyl)-1,2,4-triazin-3-amine
CN114478519B (zh) * 2020-10-23 2024-06-11 励缔(杭州)医药科技有限公司 吡唑并吡啶类化合物或其盐及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8299108B2 (en) * 2002-03-29 2012-10-30 Novartis Ag Substituted benzazoles and methods of their use as inhibitors of raf kinase
JP4628678B2 (ja) 2002-03-29 2011-02-09 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド 置換ベンズアゾールおよびRafキナーゼ阻害剤としてのそれらの使用
US20060189619A1 (en) 2005-02-24 2006-08-24 Wyeth 3-({4-[2-(4-Tert-butylphenyl)-1h-benzimidazol-4-yl]piperazin-1-yl}methyl)pyrido[2,3-b]]pyrazi ne compounds
PE20070427A1 (es) * 2005-08-30 2007-04-21 Novartis Ag Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
US7731795B2 (en) 2005-12-02 2010-06-08 Clemson University Rhombohedral fluoroberyllium borate crystals and hydrothermal growth thereof for use in laser and non-linear optical applications and devices
DK2046292T3 (da) * 2006-07-21 2010-06-07 Novartis Ag Formuleringer for benzimidazolylpyridylethere
PE20080766A1 (es) * 2006-08-30 2008-06-15 Novartis Ag Sales de benzimidazolil piridil eteres y formulaciones que las contienen

Also Published As

Publication number Publication date
NO20091236L (no) 2009-03-27
US20120308651A1 (en) 2012-12-06
EP2059518A2 (en) 2009-05-20
DK2059518T3 (da) 2011-05-16
JP2010502622A (ja) 2010-01-28
US20100168060A1 (en) 2010-07-01
CN101516870B (zh) 2013-09-11
HRP20110311T1 (hr) 2011-08-31
HK1131613A1 (en) 2010-01-29
CO6150180A2 (es) 2010-04-20
ES2360968T3 (es) 2011-06-10
MY161829A (en) 2017-05-15
BRPI0716243A2 (pt) 2013-09-03
US8202998B2 (en) 2012-06-19
IL196811A (en) 2013-03-24
ATE504584T1 (de) 2011-04-15
AU2007290388A1 (en) 2008-03-06
CA2660376A1 (en) 2008-03-06
AU2007290388B2 (en) 2011-07-14
MA30711B1 (fr) 2009-09-01
ZA200900664B (en) 2009-12-30
CY1112187T1 (el) 2015-12-09
IL196811A0 (en) 2009-11-18
MX2009002279A (es) 2009-03-20
DE602007013774D1 (de) 2011-05-19
PE20130814A1 (es) 2013-08-08
PE20080766A1 (es) 2008-06-15
SI2059518T1 (sl) 2011-06-30
NZ574620A (en) 2011-05-27
TW200819438A (en) 2008-05-01
RU2009111384A (ru) 2010-10-10
RU2457206C2 (ru) 2012-07-27
GT200900045A (es) 2010-06-14
CA2660376C (en) 2014-04-15
TN2009000068A1 (en) 2010-08-19
CL2007002533A1 (es) 2008-02-08
WO2008027523A3 (en) 2008-04-10
JO2702B1 (en) 2013-03-03
KR20090043542A (ko) 2009-05-06
PT2059518E (pt) 2011-07-11
WO2008027523A2 (en) 2008-03-06
CN101516870A (zh) 2009-08-26
US8501785B2 (en) 2013-08-06
JP5279712B2 (ja) 2013-09-04
EP2059518B1 (en) 2011-04-06

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