SI1874341T1 - Eritrociti, vsebujoči deiminazo arginina - Google Patents
Eritrociti, vsebujoči deiminazo argininaInfo
- Publication number
- SI1874341T1 SI1874341T1 SI200630327T SI200630327T SI1874341T1 SI 1874341 T1 SI1874341 T1 SI 1874341T1 SI 200630327 T SI200630327 T SI 200630327T SI 200630327 T SI200630327 T SI 200630327T SI 1874341 T1 SI1874341 T1 SI 1874341T1
- Authority
- SI
- Slovenia
- Prior art keywords
- containing arginine
- erythrocytes containing
- deimination
- erythrocytes
- arginine deimination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
- C12Y305/03006—Arginine deiminase (3.5.3.6)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0504122A FR2884717B1 (fr) | 2005-04-25 | 2005-04-25 | Erythrocytes renfermant de l'arginine deiminase |
| EP06744562A EP1874341B1 (en) | 2005-04-25 | 2006-04-25 | Erythrocytes containing arginine deiminase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1874341T1 true SI1874341T1 (sl) | 2009-08-31 |
Family
ID=35787979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630327T SI1874341T1 (sl) | 2005-04-25 | 2006-04-25 | Eritrociti, vsebujoči deiminazo arginina |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9125876B2 (sl) |
| EP (1) | EP1874341B1 (sl) |
| JP (1) | JP5339899B2 (sl) |
| KR (1) | KR101431650B1 (sl) |
| CN (1) | CN101163497B (sl) |
| AT (1) | ATE432711T1 (sl) |
| AU (1) | AU2006238917C1 (sl) |
| CA (1) | CA2606420C (sl) |
| CY (1) | CY1109353T1 (sl) |
| DE (1) | DE602006007122D1 (sl) |
| DK (1) | DK1874341T3 (sl) |
| ES (1) | ES2326549T3 (sl) |
| FR (1) | FR2884717B1 (sl) |
| PL (1) | PL1874341T3 (sl) |
| PT (1) | PT1874341E (sl) |
| SI (1) | SI1874341T1 (sl) |
| WO (1) | WO2006114691A1 (sl) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2919804B1 (fr) | 2007-08-08 | 2010-08-27 | Erytech Pharma | Composition et vaccin therapeutique anti-tumoral |
| EP2242507B1 (en) * | 2008-02-13 | 2013-02-20 | Erytech Pharma | Formulation and method for the prevention and treatment of skeletal manifestation of gaucher's disease |
| US8815232B2 (en) | 2008-08-26 | 2014-08-26 | Kyon Biotech Ag | Compositions and methods for treating cancer |
| FR2940087B1 (fr) | 2008-12-18 | 2011-05-06 | Lab Francais Du Fractionnement | Erythrocytes contenant du facteur viii, preparation et utilisations. |
| CN108117586A (zh) | 2010-08-10 | 2018-06-05 | 洛桑聚合联合学院 | 红细胞结合性治疗剂 |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9033948B2 (en) * | 2011-04-19 | 2015-05-19 | Fenwel, Inc. | Single collection bag blood collection system, method and apparatus |
| FR3005420B1 (fr) * | 2013-05-07 | 2015-09-18 | Erytech Pharma | Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues. |
| EP3071515A2 (en) | 2013-11-18 | 2016-09-28 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
| FR3017299B1 (fr) | 2014-02-12 | 2018-05-18 | Erytech Pharma | Composition pharmaceutique comprenant des erythrocytes encapsulant une enzyme a plp et son cofacteur |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| EA201691686A1 (ru) | 2014-02-21 | 2017-03-31 | Эколь Политекник Федераль Де Лозан (Эпфл) | Терапевтические средства с углевод-опосредованной адресной доставкой |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| RU2736495C2 (ru) | 2014-04-01 | 2020-11-17 | Рубиус Терапьютикс, Инк. | Способ и композиции для иммуномодуляции |
| EP3344575B1 (en) | 2015-09-04 | 2020-04-15 | SQZ Biotechnologies Company | Intracellular delivery of biomolecules to cells comprising a cell wall |
| RS62939B1 (sr) | 2016-01-11 | 2022-03-31 | Rubius Therapeutics Inc | Kompozicije i metode u vezi sa multimodalnim terapijskim ćelijskim sistemima u indikacijama kancera |
| IL262677B2 (en) | 2016-05-03 | 2025-08-01 | Sqz Biotechnologies Co | Intracellular delivery of biomolecules to suppress an immune response or to induce tolerance to an antigen in an individual |
| WO2018232176A1 (en) | 2017-06-16 | 2018-12-20 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| WO2019042628A1 (en) | 2017-08-31 | 2019-03-07 | Erytech Pharma | ARGININE DEIMINASE ENCAPSULATED WITHIN ERYTHROCYTES AND THEIR USE IN THE TREATMENT OF CANCER AND ARGINASE-1 DEFICIENCY |
| EP3449935A1 (en) * | 2017-08-31 | 2019-03-06 | Erytech Pharma | Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency |
| WO2020009740A2 (en) * | 2018-04-25 | 2020-01-09 | Washington University | Compositions and methods of use thereof for treatment of metabolic diseases and related disorders |
| EA202092723A1 (ru) | 2018-05-09 | 2021-04-09 | Зе Юниверсити Оф Чикаго | Композиции и способы, касающиеся иммунной толерантности |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| AU2021270347A1 (en) | 2020-05-11 | 2022-12-15 | Erytech Pharma | Red cell extracellular vesicles (RCEVs) containing cargoes and methods of use and production thereof |
| CN113750232B (zh) * | 2021-09-12 | 2023-06-02 | 重庆医科大学 | 一种巨噬细胞膜包覆精氨酸脱亚胺酶/过氧化氢酶/ir780纳米粒、制备方法和应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1051382A (sl) * | 1900-01-01 | |||
| DE2740053A1 (de) * | 1977-09-06 | 1979-05-03 | Klaus Prof Dr Med Gersonde | Verwendung von allosterischen effektoren mit hilfe von lipidvesikeln ueber eine irreversible inkorporierung zwecks verbesserter o tief 2 -entladung des haemoglobins in erythrozyten |
| JPH0235081A (ja) | 1988-07-26 | 1990-02-05 | Agency Of Ind Science & Technol | アルギニン・デイミナーゼおよびその用途 |
| JPH0253490A (ja) | 1988-08-16 | 1990-02-22 | Agency Of Ind Science & Technol | アルギニン・デイミナーゼ遺伝子 |
| DE58908768D1 (de) * | 1988-09-30 | 1995-01-26 | Siemens Ag | Verfahren zum synchronisierten Umtasten eines Polarisationszustandes eines optischen Sendesignals eines optischen Übertragungssystems mit Überlagerungsempfang und Vorrichtung zur Durchführung des Verfahrens. |
| JP2900279B2 (ja) | 1989-08-02 | 1999-06-02 | 株式会社ジャパンエナジー | 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤 |
| FR2678512B1 (fr) * | 1991-07-03 | 1995-06-30 | Novacell | Machine a internaliser. |
| JP3004788B2 (ja) | 1991-10-28 | 2000-01-31 | 株式会社ジャパンエナジー | アルギニンデイミナーゼ発現ベクター、形質転換微生物およびアルギニンデイミナーゼの製造法 |
| US5372942A (en) * | 1992-02-10 | 1994-12-13 | Coriell Institute For Medical Research | Protease K resistant arginine deiminase, its method of preparation and its use as an anti-neoplastic agent |
| AU680890B2 (en) * | 1993-03-23 | 1997-08-14 | Cbr Laboratories, Inc. | Method and apparatus for encapsulation of biologically-active substances in cells |
| US5804183A (en) * | 1997-01-31 | 1998-09-08 | Enzon, Inc. | Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same |
| US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
| US6183738B1 (en) * | 1997-05-12 | 2001-02-06 | Phoenix Pharamacologics, Inc. | Modified arginine deiminase |
| KR100406268B1 (ko) | 1999-12-24 | 2003-11-19 | 주식회사 안지오랩 | 아르기닌 디이미네이즈를 유효성분으로 하는 혈관신생에 의한 질환 치료용 조성물 |
| WO2002009741A1 (en) * | 2000-07-27 | 2002-02-07 | Angiolab, Inc. | The pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis |
| AU2001289132A1 (en) * | 2000-11-28 | 2002-06-11 | Phoenix Pharmacologics, Inc. | Modified arginine deiminase |
| JP4733393B2 (ja) * | 2002-11-18 | 2011-07-27 | ポラリス・グループ | インビボでウイルス複製を阻害する方法 |
| US20070105220A1 (en) * | 2003-08-06 | 2007-05-10 | The Regents Of The University Of California | Erythrocytic cells and method for loading solutes |
-
2005
- 2005-04-25 FR FR0504122A patent/FR2884717B1/fr not_active Expired - Fee Related
-
2006
- 2006-04-25 JP JP2008507191A patent/JP5339899B2/ja not_active Expired - Fee Related
- 2006-04-25 ES ES06744562T patent/ES2326549T3/es active Active
- 2006-04-25 KR KR1020077027105A patent/KR101431650B1/ko not_active Expired - Fee Related
- 2006-04-25 US US11/912,236 patent/US9125876B2/en active Active
- 2006-04-25 PT PT06744562T patent/PT1874341E/pt unknown
- 2006-04-25 DK DK06744562T patent/DK1874341T3/da active
- 2006-04-25 AU AU2006238917A patent/AU2006238917C1/en not_active Ceased
- 2006-04-25 DE DE602006007122T patent/DE602006007122D1/de active Active
- 2006-04-25 CA CA2606420A patent/CA2606420C/en active Active
- 2006-04-25 WO PCT/IB2006/001004 patent/WO2006114691A1/en not_active Ceased
- 2006-04-25 CN CN2006800137421A patent/CN101163497B/zh not_active Expired - Fee Related
- 2006-04-25 AT AT06744562T patent/ATE432711T1/de active
- 2006-04-25 PL PL06744562T patent/PL1874341T3/pl unknown
- 2006-04-25 SI SI200630327T patent/SI1874341T1/sl unknown
- 2006-04-25 EP EP06744562A patent/EP1874341B1/en active Active
-
2009
- 2009-08-28 CY CY20091100903T patent/CY1109353T1/el unknown
-
2015
- 2015-07-31 US US14/815,203 patent/US9968663B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2326549T3 (es) | 2009-10-14 |
| KR101431650B1 (ko) | 2014-08-20 |
| JP5339899B2 (ja) | 2013-11-13 |
| JP2008538761A (ja) | 2008-11-06 |
| AU2006238917B2 (en) | 2011-04-07 |
| US20160030532A1 (en) | 2016-02-04 |
| FR2884717A1 (fr) | 2006-10-27 |
| US9968663B2 (en) | 2018-05-15 |
| EP1874341A1 (en) | 2008-01-09 |
| CN101163497B (zh) | 2012-12-19 |
| CY1109353T1 (el) | 2014-07-02 |
| PL1874341T3 (pl) | 2009-12-31 |
| HK1112187A1 (en) | 2008-08-29 |
| AU2006238917C1 (en) | 2011-08-04 |
| KR20080000678A (ko) | 2008-01-02 |
| US9125876B2 (en) | 2015-09-08 |
| FR2884717B1 (fr) | 2009-07-03 |
| EP1874341B1 (en) | 2009-06-03 |
| ATE432711T1 (de) | 2009-06-15 |
| WO2006114691A1 (en) | 2006-11-02 |
| DE602006007122D1 (de) | 2009-07-16 |
| DK1874341T3 (da) | 2009-08-03 |
| CN101163497A (zh) | 2008-04-16 |
| PT1874341E (pt) | 2009-07-21 |
| AU2006238917A1 (en) | 2006-11-02 |
| CA2606420C (en) | 2015-01-27 |
| CA2606420A1 (en) | 2006-11-02 |
| US20080274092A1 (en) | 2008-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI1874341T1 (sl) | Eritrociti, vsebujoči deiminazo arginina | |
| Pader et al. | Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase | |
| ATE508190T1 (de) | Mehrfachpromotor-expressionskassetten zurgleichzeitigen zuführung von rnai-agentien | |
| BRPI0508470A (pt) | sistema de teste in vitro para prever toleráncia do paciente aos agentes terapêuticos | |
| WO2011035001A3 (en) | Novel heparin entities and methods of use | |
| NO20081013L (no) | 7-substituerte aza-indazoler, sammensetninger inneholdende disse, produksjonsmetode og anvendelse derav | |
| EA200900091A1 (ru) | Новые показания к применению прямых ингибиторов тромбина в лечении сердечно-сосудистых заболеваний | |
| NO20082120L (no) | Behandling og forebyggelse av mikroangiopati | |
| EA200970397A1 (ru) | Ингибиторы трипсинподобной серинпротеазы, их получение и применение | |
| WO2007048042A3 (en) | Small molecule inhibitors of hiv-1 capsid assembly | |
| WO2006095259A3 (en) | Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds | |
| WO2008054534A3 (en) | Screening systems utilizing rtp801 | |
| Yu et al. | Prodrugs of persulfides, sulfur dioxide, and carbon disulfide: important tools for studying sulfur signaling at various oxidation states | |
| WO2008106594A3 (en) | Inhibitors of nucleophosmin (npm) and methods for inducing apoptosis | |
| Wang et al. | Inhibition of endoplasmic reticulum stress cooperates with SLC7A11 to promote disulfidptosis and suppress tumor growth upon glucose limitation | |
| CY1113525T1 (el) | Θεραπεια στοχευσης καθεψινης s | |
| CY1118302T1 (el) | Λωριδα χαρτιου για τον καθορισμο των ελαχιστων ανασταλτικων συγκεντρωσεων αντιβιοτικων | |
| Banno et al. | Identification of 3-aminomethyl-1, 2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 | |
| EA200870434A1 (ru) | Аминопроизводные андростанов и андростенов как лекарственные средства против сердечно-сосудистых нарушений | |
| WO2006075095A3 (fr) | Utilisation de derives de la purine comme inhibiteurs de la proteine hsp90 et pour le traitement du cancer | |
| EA200800357A1 (ru) | Новые фармацевтические соединения | |
| ATE485261T1 (de) | Salicylsäurederivate | |
| ATE474567T1 (de) | Kombinationspräparate enthaltend 2- methylthiazolidin-2,4-dicarbonsäure | |
| Kinoshita | Effects of oxidative stress on vascular function, and the role of anesthetics | |
| WO2008073634A3 (en) | Compositions and methods for detecting and treating endothelial dysfunction |