[go: up one dir, main page]

SI1663989T1 - Kristalinična oblika kalcijeve soli bis((E)-7-(4-(4-fluorofenil)-6-izopropil-2-(metil(metilsulfonil)amino) pirimidin-5-il)(3R,5S)-3,5-dihidroksihept-6-enojske kisline) - Google Patents

Kristalinična oblika kalcijeve soli bis((E)-7-(4-(4-fluorofenil)-6-izopropil-2-(metil(metilsulfonil)amino) pirimidin-5-il)(3R,5S)-3,5-dihidroksihept-6-enojske kisline)

Info

Publication number
SI1663989T1
SI1663989T1 SI200431145T SI200431145T SI1663989T1 SI 1663989 T1 SI1663989 T1 SI 1663989T1 SI 200431145 T SI200431145 T SI 200431145T SI 200431145 T SI200431145 T SI 200431145T SI 1663989 T1 SI1663989 T1 SI 1663989T1
Authority
SI
Slovenia
Prior art keywords
enoicacid
sqb
dihydroxyhept
opropyl
methylsulfonyl
Prior art date
Application number
SI200431145T
Other languages
English (en)
Inventor
Rebecca Jane Booth
Peter Anthony Cittern
Jeffrey Norman Crabb
John Astrazeneca Avlon Horbury
David Wyn Calvert Jones
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34276833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1663989(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0321127A external-priority patent/GB0321127D0/en
Priority claimed from GB0404859A external-priority patent/GB0404859D0/en
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of SI1663989T1 publication Critical patent/SI1663989T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
SI200431145T 2003-09-10 2004-09-08 Kristalinična oblika kalcijeve soli bis((E)-7-(4-(4-fluorofenil)-6-izopropil-2-(metil(metilsulfonil)amino) pirimidin-5-il)(3R,5S)-3,5-dihidroksihept-6-enojske kisline) SI1663989T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0321127A GB0321127D0 (en) 2003-09-10 2003-09-10 Chemical compounds
GB0404859A GB0404859D0 (en) 2004-03-04 2004-03-04 Chemical compound
PCT/GB2004/003829 WO2005023779A1 (en) 2003-09-10 2004-09-08 Crystalline form of bis [(e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6 -enoicacid] calcium salt
EP04768376A EP1663989B1 (en) 2003-09-10 2004-09-08 CRYSTALLINE FORM OF BIS (E)-7- 4-(4-FLUOROPHENYL)-6-IS OPROPYL-2- METHYL(METHYLSULFONYL)AMINO PYRIMIDIN-5-YL&r sqb;(3R,5S)-3,5-DIHYDROXYHEPT-6 -ENOICACID CALCIUM SALT

Publications (1)

Publication Number Publication Date
SI1663989T1 true SI1663989T1 (sl) 2009-08-31

Family

ID=34276833

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431145T SI1663989T1 (sl) 2003-09-10 2004-09-08 Kristalinična oblika kalcijeve soli bis((E)-7-(4-(4-fluorofenil)-6-izopropil-2-(metil(metilsulfonil)amino) pirimidin-5-il)(3R,5S)-3,5-dihidroksihept-6-enojske kisline)

Country Status (31)

Country Link
US (4) US20060293355A1 (sl)
EP (1) EP1663989B1 (sl)
JP (1) JP2007505090A (sl)
KR (1) KR20070019943A (sl)
CN (1) CN1878760B (sl)
AR (1) AR045628A1 (sl)
AT (1) ATE428701T1 (sl)
AU (1) AU2004270467B8 (sl)
BR (1) BRPI0414236A (sl)
CA (1) CA2537962C (sl)
CO (1) CO5670355A2 (sl)
CY (1) CY1109173T1 (sl)
DE (1) DE602004020640D1 (sl)
DK (1) DK1663989T3 (sl)
ES (1) ES2324042T3 (sl)
HR (1) HRP20090335T1 (sl)
IL (1) IL174073A (sl)
IS (1) IS2689B (sl)
MX (1) MXPA06002761A (sl)
MY (1) MY142615A (sl)
NO (1) NO336358B1 (sl)
NZ (1) NZ545785A (sl)
PL (1) PL1663989T3 (sl)
PT (1) PT1663989E (sl)
RU (1) RU2363697C2 (sl)
SA (1) SA04250297B1 (sl)
SI (1) SI1663989T1 (sl)
TW (1) TWI370817B (sl)
UA (1) UA85062C2 (sl)
UY (1) UY28501A1 (sl)
WO (1) WO2005023779A1 (sl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
GB0011120D0 (en) * 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL159741A0 (en) 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
BR0317313A (pt) 2002-12-16 2005-11-08 Astrazeneca Uk Ltd Processo para a preparação de um composto, e, composto
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
WO2008036286A1 (en) * 2006-09-18 2008-03-27 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin calcium
TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process
SI2752407T1 (sl) * 2009-01-14 2016-07-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalni kalcijev rosuvastatin trihidrat
BRPI1005147A2 (pt) * 2009-01-15 2019-09-24 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag processo de preparação de sais de rosuvastatina
HUP0900285A2 (en) 2009-05-07 2011-01-28 Egis Gyogyszergyar Nyilvanosan Mukoedoe Reszvenytarsasag Rosuvastatin salts and preparation thereof
WO2011074016A1 (en) 2009-12-17 2011-06-23 Matrix Laboratories Ltd Novel polymorphic forms of rosuvastatin calcium and process for preparation of the same
HU230737B1 (hu) 2010-11-16 2018-01-29 EGIS Gyógyszergyár Nyrt Eljárás rosuvastatin só előállítására
WO2012069394A1 (en) 2010-11-22 2012-05-31 Basf Se Multicomponent system of rosuvastatin calcium salt and sorbitol
DE202012011888U1 (de) 2011-04-18 2013-03-21 Basf Se Kristallines Mehrkomponentensystem von Rosuvastatin-Calciumsalz und Vanillin
WO2014050874A1 (ja) * 2012-09-27 2014-04-03 東和薬品株式会社 ロスバスタチンカルシウムの新規結晶形態およびその製造方法
RO129060B1 (ro) 2013-04-25 2014-11-28 Antibiotice S.A. Compoziţie farmaceutică stabilă cu rosuvastatină calcică amorfă
US9695130B2 (en) 2014-02-06 2017-07-04 Api Corporation Rosuvastatin calcium and process for producing intermediate thereof
WO2017183040A1 (en) 2016-04-18 2017-10-26 Morepen Laboratories Limited New polymorphic form of crystalline rosuvastatin calcium & novel processes for crystalline as well as amorphous rosuvastatin calcium
CN105837516B (zh) * 2016-05-16 2018-07-10 山东新时代药业有限公司 一种瑞舒伐他汀钙晶型及其制备方法
EP3653329B1 (en) 2017-09-13 2023-10-11 JFE Steel Corporation Double-sided friction stir welding method for metal plate
CN120456997A (zh) 2023-01-25 2025-08-08 杰富意钢铁株式会社 拼焊坯件以及拼焊坯件的制造方法及制造设备

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645858A (en) * 1982-03-22 1987-02-24 G. D. Searle & Co. Pentanedioic acid derivatives
DE3741509A1 (de) * 1987-12-08 1989-06-22 Hoechst Ag Verfahren zur herstellung optisch aktiver 3-desmethylmevalonsaeurederivate sowie zwischenprodukte
EP0367895A1 (en) 1988-10-06 1990-05-16 Sandoz Ag Pyrimidinyl-substituted hydroxyacids, lactones and esters and pharmaceutical compositions containing them
US5026698A (en) * 1988-11-02 1991-06-25 Nissan Chemical Industries, Ltd. Thienopyridine type mevalonolactones
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
WO1993008823A1 (en) 1991-11-06 1993-05-13 Tanabe Seiyaku Co., Ltd. Guanidinyl and related cell adhesion modulation compounds
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
ATE158579T1 (de) * 1992-07-02 1997-10-15 Hoechst Ag Verfahren zur herstellung von (3r,5s)6-hydroxy- 3,5-0-isopropyliden-3,5-dihydroxy-hexansäure- tert.-butylester
DE69634054T2 (de) 1995-07-17 2005-12-08 Warner-Lambert Co. Kristalline (R-(R*, R*))-2-(4-Fluorophenyl)-β, δ-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-((Phenylamino)Carbonyl)-1H-Pyrrol-1-Heptancarbonsäure Hemi Calcium Salz (Atorvastatin)
FR2741620B1 (fr) 1995-11-28 1997-12-26 Oreal Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
US6278001B1 (en) * 1995-11-28 2001-08-21 L'oréal Method for preparing (+) compactin and (+) mevinolin analog compounds having a β-hydroxy-δ-lactone grouping
PT907639E (pt) 1996-06-24 2003-06-30 Novartis Ag Compostos polimorficos
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
EP1055671B1 (en) * 1998-12-10 2004-12-01 Kaneka Corporation A process for producing a simvastatin precursor
GB9900339D0 (en) * 1999-01-09 1999-02-24 Zeneca Ltd Chemical compounds
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
AU7717500A (en) 1999-09-30 2001-04-30 Merck & Co., Inc. Anti-hypercholesterolemic drug combination
SI1535613T1 (sl) 1999-11-17 2010-12-31 Teva Pharma Postopek za pripravo polimorfne oblike atorvastatin kalcija
GB0001621D0 (en) 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
GB0003305D0 (en) * 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
AU2000254249A1 (en) 2000-03-28 2001-10-08 Biocon India Limited Synthesis of (r-(r*,r*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
GB0011163D0 (en) 2000-05-10 2000-06-28 Astrazeneca Ab Chemical compound
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
HRP20030347A2 (en) 2000-10-05 2005-04-30 Teva Gy�gyszergy�r R�szv�nyt�rsas�g Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
IL155890A0 (en) 2000-11-16 2003-12-23 Teva Pharma HYDROLYSIS OF [R(R*,R*)]-2-(4-FLUOROPHENYL)-beta,delta-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID ESTERS WITH CALCIUM HYDROXIDE
IL156055A0 (en) 2000-11-30 2003-12-23 Teva Pharma Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
NL1017548C2 (nl) 2001-03-09 2002-09-10 Synthon Bv Een lactonisatie proces.
IN190564B (sl) 2001-04-11 2003-08-09 Cadila Heathcare Ltd
JP2004536813A (ja) * 2001-06-06 2004-12-09 ブリストル−マイヤーズ　スクイブ　カンパニー キラルジオールスルホンおよびジヒドロキシ酸ＨＭＧＣｏＡレダクタ−ゼ阻害剤
IL159741A0 (en) * 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
IL160077A0 (en) 2001-08-16 2004-06-20 Teva Pharma Processes for preparing calcium salt forms of statins
KR20040026705A (ko) * 2001-08-16 2004-03-31 테바 파마슈티컬 인더스트리즈 리미티드 스타틴의 칼슘 염 형태의 제조 방법
IL160043A0 (en) 2001-08-22 2004-06-20 Ciba Sc Holding Ag Process for the preparation of indole derivatives
JP2005512516A (ja) 2001-09-24 2005-05-12 メルク　エンド　カムパニー　インコーポレーテッド スタチン薬物の組合せのスクリーニング方法および選択方法
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma
EP1323717A1 (en) * 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
KR100511533B1 (ko) 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
AU2003228010A1 (en) 2002-05-21 2003-12-02 Ranbaxy Laboratories Limited Process for the preparation of rosuvastatin
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
DE10228103A1 (de) 2002-06-24 2004-01-15 Bayer Cropscience Ag Fungizide Wirkstoffkombinationen
GB0218781D0 (en) * 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
BR0317313A (pt) 2002-12-16 2005-11-08 Astrazeneca Uk Ltd Processo para a preparação de um composto, e, composto
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
US7563748B2 (en) 2003-06-23 2009-07-21 Cognis Ip Management Gmbh Alcohol alkoxylate carriers for pesticide active ingredients
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0321827D0 (en) * 2003-09-18 2003-10-15 Astrazeneca Uk Ltd Chemical compounds
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
DE10352659B4 (de) 2003-11-11 2007-09-13 Ratiopharm Gmbh Verfahren zur Herstellung von Statinen und Tetrahydropyranonderivate zur Verwendung in dem Verfahren
WO2005054207A1 (en) * 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
US7241800B2 (en) * 2004-03-17 2007-07-10 Mai De Ltd. Anhydrous amorphous form of fluvastatin sodium
US7161004B2 (en) * 2004-06-21 2007-01-09 Dr. Reddy's Laboratories Limited Processes to produce intermediates for rosuvastatin
RU2346996C2 (ru) 2004-06-29 2009-02-20 ЮРОПИЭН НИКЕЛЬ ПиЭлСи Усовершенствованное выщелачивание основных металлов
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
WO2007000020A1 (en) 2005-06-29 2007-01-04 Compumedics Limited Sensor assembly with conductive bridge
TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process

Also Published As

Publication number Publication date
DE602004020640D1 (de) 2009-05-28
DK1663989T3 (da) 2009-07-06
US20100222373A1 (en) 2010-09-02
KR20070019943A (ko) 2007-02-16
CA2537962A1 (en) 2005-03-17
BRPI0414236A (pt) 2006-10-31
RU2363697C2 (ru) 2009-08-10
MXPA06002761A (es) 2006-12-14
US20060293355A1 (en) 2006-12-28
US8436167B2 (en) 2013-05-07
CO5670355A2 (es) 2006-08-31
PL1663989T3 (pl) 2009-08-31
MY142615A (en) 2010-12-15
ATE428701T1 (de) 2009-05-15
US20120059022A1 (en) 2012-03-08
CA2537962C (en) 2012-10-23
AR045628A1 (es) 2005-11-02
PT1663989E (pt) 2009-06-09
NO336358B1 (no) 2015-08-03
IL174073A0 (en) 2006-08-01
IS2689B (is) 2010-10-15
EP1663989B1 (en) 2009-04-15
TWI370817B (en) 2012-08-21
AU2004270467A1 (en) 2005-03-17
SA04250297B1 (ar) 2008-11-18
CY1109173T1 (el) 2014-07-02
ES2324042T3 (es) 2009-07-29
CN1878760A (zh) 2006-12-13
RU2006111354A (ru) 2007-10-27
IL174073A (en) 2014-03-31
UA85062C2 (uk) 2008-12-25
WO2005023779A1 (en) 2005-03-17
AU2004270467B8 (en) 2008-09-18
HRP20090335T1 (hr) 2009-07-31
JP2007505090A (ja) 2007-03-08
TW200526595A (en) 2005-08-16
CN1878760B (zh) 2011-11-09
IS8385A (is) 2006-03-30
UY28501A1 (es) 2005-04-29
NZ545785A (en) 2010-03-26
HK1090361A1 (en) 2006-12-22
NO20061181L (no) 2006-03-29
AU2004270467B2 (en) 2008-08-21
US20130225622A1 (en) 2013-08-29
EP1663989A1 (en) 2006-06-07

Similar Documents

Publication Publication Date Title
PL1663989T3 (pl) Krystaliczna postać soli wapniowej kwasu bis[(E)-7-[4-(4-fluorofenylo)-6-izopropylo-2-metylo[(metylosulfonylo)-amino-pirymidyn-5-ylo](3R,5S)-3,5-dihydroksyhept-6-enowego]
SI1682536T1 (sl) Postopek izdelave kalcijeve soli rosuvastatin-(E)-7-(4-(4-fluorofenil) -6-izopropil-2-(metil(metilsulfonil)amino)pirimidin-5-il) (3r,5s)-3,5- dihidroksihept-6-enojske kisline in njenih kristalnih vmesnih spojin
DK1539711T3 (da) Fremgangsmåde til fremstilling af calciumsaltet af rosuvastatin
SI1873148T1 (sl) Farmacevtski sestavki, ki vsebujejo kristalinične soli 7-(4-(4-fluorofenil)-6-izopropil-2-(metil)(metilsulfonil)amino)pirimidin -5-il)-(3R,5S)-3,5-dihidroksihept-6-enojske kisline
ZA200409981B (en) Novel formate salt of O-desmethyl-venlafaxine
ZA200701199B (en) ( 1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo [3.2.0]heptane benzenesulfonate
IL173858A0 (en) Process for preparation of rosuvastatin calcium
WO2003047520A3 (en) SUBSTITUTED AMINO METHYL FACTOR Xa INHIBITORS
IL184779A0 (en) Novel pyrimidine nucleoside compound or salt thereof
AU2003299100A1 (en) Pyrimidine compounds as therapeutic agents
AU2003294747A1 (en) Stabilised compositions containing polyfunctional aziridine compounds as hardening constituents
PL1704144T3 (pl) Sposób wytwarzania soli wapniowej kwasu (E)-7-[4-(4-fluorofenylo)-6-izopropylo-2-[metylo(metylosulfonylo)amino]pirymidyn-5-ylo](3R,5S)-3,5-dihydroksy-6-heptenowego
DK1622629T3 (da) Strontiumsaltsammensætning med kontrolleret frisætning
HK1090909A (en) Calcium carbonate granulation
AU2003208225A1 (en) Fish hydrolysates as salt replacement
GB0206255D0 (en) Novel salt forms