SI1102762T1 - 2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists - Google Patents

2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists

Info

Publication number: SI1102762T1
Authority: SI; Slovenia
Prior art keywords: orl1; piperidyl; substituted; receptor agonists; benzimidazole compounds
Prior art date: 1998-08-06

Application number

SI9930151T

Other languages

English (en)

Slovenian (sl)

Inventor

Fumitaka Pfizer Pharmaceuticals Inc. ITO

Hirohide Pfizer Pharmaceuticals Inc. NOGUCHI

Hiroshi Pfizer Pharmaceuticals Inc. KONDO

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-06

Filing date

1999-07-05

Publication date

2003-04-30

1999-07-05 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2003-04-30 Publication of SI1102762T1 publication Critical patent/SI1102762T1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Cardiology (AREA)
Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Toxicology (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SI9930151T 1998-08-06 1999-07-05 2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists SI1102762T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IBPCT/IB98/01206		1998-08-06
PCT/IB1999/001239 WO2000008013A2 (fr)	1998-08-06	1999-07-05	Composés de 1-pipéridyl benzimidazole substitué en 2, agonistes du récepteur orl1
EP99926688A EP1102762B1 (fr)	1998-08-06	1999-07-05	Composes de 1-piperidyl benzimidazole substitue en 2, agonistes du recepteur orl1

Publications (1)

Publication Number	Publication Date
SI1102762T1 true SI1102762T1 (en)	2003-04-30

Family

ID=11004738

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9930151T SI1102762T1 (en)	1998-08-06	1999-07-05	2-substituted-1-piperidyl benzimidazole compounds as orl1-receptor agonists

Country Status (44)

Country	Link
US (1)	US6172067B1 (fr)
EP (1)	EP1102762B1 (fr)
JP (1)	JP3367945B2 (fr)
CN (1)	CN1317968A (fr)
AP (1)	AP2001002063A0 (fr)
AR (1)	AR018686A1 (fr)
AT (1)	ATE227716T1 (fr)
AU (1)	AU749166B2 (fr)
BG (1)	BG105301A (fr)
BR (1)	BR9912778A (fr)
CA (1)	CA2339621C (fr)
CZ (1)	CZ2001397A3 (fr)
DE (1)	DE69903953T2 (fr)
DK (1)	DK1102762T3 (fr)
EA (1)	EA200100104A1 (fr)
EE (1)	EE200100075A (fr)
ES (1)	ES2185357T3 (fr)
GE (1)	GEP20033000B (fr)
GT (1)	GT199900125A (fr)
HK (1)	HK1040188A1 (fr)
HN (1)	HN1999000105A (fr)
HR (1)	HRP20010089B1 (fr)
HU (1)	HUP0103567A3 (fr)
ID (1)	ID27212A (fr)
IL (1)	IL141029A0 (fr)
IS (1)	IS5812A (fr)
MA (1)	MA26659A1 (fr)
NO (1)	NO20010603L (fr)
NZ (1)	NZ509299A (fr)
OA (1)	OA11590A (fr)
PA (1)	PA8477701A1 (fr)
PE (1)	PE20000868A1 (fr)
PL (1)	PL346211A1 (fr)
PT (1)	PT1102762E (fr)
SI (1)	SI1102762T1 (fr)
SK (1)	SK1602001A3 (fr)
SV (1)	SV1999000099A (fr)
TN (1)	TNSN99142A1 (fr)
TR (1)	TR200100403T2 (fr)
TW (1)	TW513424B (fr)
UY (1)	UY25659A1 (fr)
WO (1)	WO2000008013A2 (fr)
YU (1)	YU8201A (fr)
ZA (1)	ZA200100900B (fr)

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US6340681B1 (en) *	1999-07-16	2002-01-22	Pfizer Inc	2-benzimidazolylamine compounds as ORL-1-receptor agonists
SE9902987D0 (sv)	1999-08-24	1999-08-24	Astra Pharma Prod	Novel compounds
SE9903544D0 (sv)	1999-10-01	1999-10-01	Astra Pharma Prod	Novel compounds
EP1122257B1 (fr) *	2000-01-05	2005-10-12	Pfizer Inc.	Composés de benzimidazole comme agonistes du récepteur ORL1
GB2359078A (en)	2000-02-11	2001-08-15	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
GB2359081A (en)	2000-02-11	2001-08-15	Astrazeneca Uk Ltd	Pharmaceutically active thiazolopyrimidines
GB2359551A (en)	2000-02-23	2001-08-29	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
GB0005642D0 (en)	2000-03-10	2000-05-03	Astrazeneca Uk Ltd	Chemical compounds
SE0003828D0 (sv)	2000-10-20	2000-10-20	Astrazeneca Ab	Novel compounds
AU2403802A (en)	2000-11-15	2002-05-27	Banyu Pharma Co Ltd	Benzimidazole derivatives
GB0104050D0 (en)	2001-02-19	2001-04-04	Astrazeneca Ab	Chemical compounds
GB0107228D0 (en)	2001-03-22	2001-05-16	Astrazeneca Ab	Chemical compounds
SE0101322D0 (sv)	2001-04-12	2001-04-12	Astrazeneca Ab	Novel compounds
ES2340441T3 (es) *	2001-04-18	2010-06-02	Euro-Celtique S.A.	Compuestos de octahidrobencimidazolona como analgesicos.
JP4489354B2 (ja)	2001-04-18	2010-06-23	ユーロ−セルティークエス．エイ．	スピロインデンおよびスピロインダン化合物類
SI1598338T1 (sl) *	2001-04-18	2009-06-30	Euro Celtique Sa	Derivati 1-(4-piperidinil)-1,3-dihidro-2H-indol-2-ona in sorodne spojine kot analogi nociceptina in ligandi ORL1 za zdravljenje bolečine
AU2002303406B2 (en) *	2001-04-18	2006-03-30	Euro-Celtique S.A.	Nociceptin analogs
ATE403429T1 (de)	2001-04-18	2008-08-15	Euro Celtique Sa	Spiropyrazol-verbindungen
JP2005502619A (ja) *	2001-07-02	2005-01-27	オメロスコーポレイション	オピオイドレセプター様レセプター１アゴニストと交替でオピオイドレセプターアゴニストを投与することを含む、痛覚脱失を生成するための方法
US20030040479A1 (en) *	2001-07-02	2003-02-27	Omeros Corporation	Rotational intrathecal analgesia method and device
SE0102716D0 (sv) *	2001-08-14	2001-08-14	Astrazeneca Ab	Novel compounds
SE0103818D0 (sv) *	2001-11-15	2001-11-15	Astrazeneca Ab	Chemical compounds
WO2003049736A1 (fr) *	2001-12-11	2003-06-19	Sepracor, Inc.	Piperidines 4-substitues, et methodes d'utilisation
ES2392340T3 (es)	2002-03-29	2012-12-07	Mitsubishi Tanabe Pharma Corporation	Remedio para los trastornos del sueño
GB0221828D0 (en)	2002-09-20	2002-10-30	Astrazeneca Ab	Novel compound
GB0221829D0 (en) *	2002-09-20	2002-10-30	Astrazeneca Ab	Novel compound
DE10252666A1 (de)	2002-11-11	2004-08-05	Grünenthal GmbH	N-Piperidyl-cyclohexan-Derivate
DE10252665A1 (de)	2002-11-11	2004-06-03	Grünenthal GmbH	4-Aminomethyl-1-aryl-cyclohexylamin-Derivate
SE0301369D0 (sv)	2003-05-09	2003-05-09	Astrazeneca Ab	Chemical compounds
GB0315203D0 (en) *	2003-06-28	2003-08-06	Celltech R&D Ltd	Chemical compounds
SA04250305B1 (ar)	2003-09-25	2008-06-02	سولفاي فارماسوتيكالز بي . في	مشتقات بنزيميدازولون cenzimidazolone وكينازولينون quinazolinone كمساعادات على مستقبلات ORL1 البشرية
GB0328243D0 (en)	2003-12-05	2004-01-07	Astrazeneca Ab	Methods
WO2005060947A2 (fr) *	2003-12-19	2005-07-07	Sri International	Ligands agonistes et antagonistes du recepteur de la nociceptine
WO2006038738A1 (fr) *	2004-10-08	2006-04-13	Takeda Pharmaceutical Company Limited	Agent de régulation du fonctionnement d'un récepteur
EP1838306B1 (fr)	2005-01-11	2010-11-17	NeuroSearch A/S	Nouveaux derives de 2-amino benzimidazole et leur utilisation en tant que modulateurs des canaux a potassium actives par le calcium a faible conductance
WO2008003667A2 (fr) *	2006-07-03	2008-01-10	Neurosearch A/S	Compositions pharmaceutiques
JP5462633B2 (ja) *	2007-01-16	2014-04-02	パーデュー、ファーマ、リミテッド、パートナーシップ	複素環置換ピペリジン化合物とその使用
TWI448289B (zh) *	2007-08-31	2014-08-11	Purdue Pharma Lp	經取代之喹啉型哌啶化合物及其用途
US8119661B2 (en) *	2007-09-11	2012-02-21	Astrazeneca Ab	Piperidine derivatives and their use as muscarinic receptor modulators
EP2324013B3 (fr)	2008-07-21	2014-10-22	Purdue Pharma LP	Composés pipéridine à liaison et substitués par une quinoxaline, et leurs utilisations
WO2012018668A1 (fr)	2010-08-05	2012-02-09	Amgen Inc.	Composés benzimidazole et azabenzimidazole qui inhibent la kinase des lymphomes anaplasiques
US9169203B2 (en)	2012-01-06	2015-10-27	Novus International, Inc.	Sulfoxide-based surfactants
WO2013119959A1 (fr)	2012-02-09	2013-08-15	Novus International Inc.	Hétéroatomes contenant des dimères cycliques
JO3300B1 (ar)	2012-06-06	2018-09-16	Novartis Ag	مركبات وتركيبات لتعديل نشاط egfr
CA2878617A1 (fr)	2012-07-12	2014-01-16	Houston Stephen Smith	Compositions de matrice et de couche pour la protection de composes bioactifs
US9085561B2 (en) *	2012-07-30	2015-07-21	Purdue Pharma L.P.	Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
WO2014102594A2 (fr)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Composés de pipéridine de type benzimidazole substitué et leurs utilisations
EP2976077A4 (fr)	2013-03-22	2016-11-30	Scripps Research Inst	Benzimidazoles substitués en tant que modulateurs d'un récepteur de nociceptine
EP3922630A1 (fr)	2014-03-20	2021-12-15	Capella Therapeutics, Inc.	Dérivés de benzimidazole en tant qu'inhibiteurs de la tyrosine kinase erbb pour le traitement du cancer
CN112707851A (zh)	2015-11-12	2021-04-27	诺华丝国际股份有限公司	作为溶剂的含硫化合物
US10584306B2 (en)	2017-08-11	2020-03-10	Board Of Regents Of The University Of Oklahoma	Surfactant microemulsions

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EP0813065A3 (fr)	1996-06-13	1998-07-22	F. Hoffmann-La Roche Ag	Modulation de la fonction d'un récepteur LC-132(analogue à opioide)
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ATE276242T1 (de)	1997-05-30	2004-10-15	Banyu Pharma Co Ltd	2-oxoimidazol-derivate
WO1999003880A1 (fr)	1997-07-15	1999-01-28	Novo Nordisk A/S	Analogues de nociceptine
US5929035A (en)	1998-04-14	1999-07-27	Regents Of The University Of Michigan	Methods of treating intestinal disorders
ID29137A (id)	1998-07-27	2001-08-02	Schering Corp	Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1

1999
- 1999-06-25 MA MA25646A patent/MA26659A1/fr unknown
- 1999-06-28 TW TW088110899A patent/TW513424B/zh not_active IP Right Cessation
- 1999-07-05 WO PCT/IB1999/001239 patent/WO2000008013A2/fr not_active Ceased
- 1999-07-05 JP JP2000563646A patent/JP3367945B2/ja not_active Expired - Fee Related
- 1999-07-05 SK SK160-2001A patent/SK1602001A3/sk unknown
- 1999-07-05 BR BR9912778-4A patent/BR9912778A/pt not_active Application Discontinuation
- 1999-07-05 EP EP99926688A patent/EP1102762B1/fr not_active Expired - Lifetime
- 1999-07-05 GE GEAP19995740A patent/GEP20033000B/en unknown
- 1999-07-05 HR HR970081A patent/HRP20010089B1/xx not_active IP Right Cessation
- 1999-07-05 DE DE69903953T patent/DE69903953T2/de not_active Expired - Fee Related
- 1999-07-05 HK HK02101444.8A patent/HK1040188A1/zh unknown
- 1999-07-05 EE EEP200100075A patent/EE200100075A/xx unknown
- 1999-07-05 NZ NZ509299A patent/NZ509299A/en not_active Application Discontinuation
- 1999-07-05 TR TR2001/00403T patent/TR200100403T2/xx unknown
- 1999-07-05 PT PT99926688T patent/PT1102762E/pt unknown
- 1999-07-05 AU AU43859/99A patent/AU749166B2/en not_active Ceased
- 1999-07-05 ES ES99926688T patent/ES2185357T3/es not_active Expired - Lifetime
- 1999-07-05 IL IL14102999A patent/IL141029A0/xx unknown
- 1999-07-05 TN TNTNSN99142A patent/TNSN99142A1/fr unknown
- 1999-07-05 ID IDW20010284D patent/ID27212A/id unknown
- 1999-07-05 EA EA200100104A patent/EA200100104A1/ru unknown
- 1999-07-05 YU YU8201A patent/YU8201A/sh unknown
- 1999-07-05 HU HU0103567A patent/HUP0103567A3/hu unknown
- 1999-07-05 CZ CZ2001397A patent/CZ2001397A3/cs unknown
- 1999-07-05 CN CN99810857A patent/CN1317968A/zh active Pending
- 1999-07-05 OA OA1200100031A patent/OA11590A/en unknown
- 1999-07-05 PL PL99346211A patent/PL346211A1/xx not_active Application Discontinuation
- 1999-07-05 AP APAP/P/2001/002063A patent/AP2001002063A0/en unknown
- 1999-07-05 SI SI9930151T patent/SI1102762T1/xx unknown
- 1999-07-05 AT AT99926688T patent/ATE227716T1/de not_active IP Right Cessation
- 1999-07-05 HN HN1999000105A patent/HN1999000105A/es unknown
- 1999-07-05 CA CA002339621A patent/CA2339621C/fr not_active Expired - Fee Related
- 1999-07-05 DK DK99926688T patent/DK1102762T3/da active
- 1999-07-06 AR ARP990103264A patent/AR018686A1/es active IP Right Grant
- 1999-07-15 PE PE1999000717A patent/PE20000868A1/es not_active Application Discontinuation
- 1999-07-16 SV SV1999000099A patent/SV1999000099A/es not_active Application Discontinuation
- 1999-07-16 PA PA19998477701A patent/PA8477701A1/es unknown
- 1999-08-05 US US09/369,208 patent/US6172067B1/en not_active Expired - Fee Related
- 1999-08-06 GT GT199900125A patent/GT199900125A/es unknown
- 1999-08-13 UY UY25659A patent/UY25659A1/es not_active Application Discontinuation
2001
- 2001-01-16 IS IS5812A patent/IS5812A/is unknown
- 2001-02-01 ZA ZA200100900A patent/ZA200100900B/xx unknown
- 2001-02-05 NO NO20010603A patent/NO20010603L/no not_active Application Discontinuation
- 2001-03-01 BG BG105301A patent/BG105301A/xx unknown

Also Published As

Publication number	Publication date
OA11590A (en)	2004-08-18
IS5812A (is)	2001-01-16
DK1102762T3 (da)	2002-12-16
ATE227716T1 (de)	2002-11-15
CA2339621C (fr)	2005-04-05
EE200100075A (et)	2002-06-17
HUP0103567A2 (hu)	2002-02-28
ES2185357T3 (es)	2003-04-16
GT199900125A (es)	2001-01-27
HRP20010089B1 (en)	2003-04-30
DE69903953T2 (de)	2003-03-27
AU749166B2 (en)	2002-06-20
TW513424B (en)	2002-12-11
NZ509299A (en)	2003-05-30
PT1102762E (pt)	2003-02-28
PL346211A1 (en)	2002-01-28
GEP20033000B (en)	2003-06-25
HN1999000105A (es)	2000-11-11
IL141029A0 (en)	2002-02-10
HUP0103567A3 (en)	2003-01-28
EA200100104A1 (ru)	2001-08-27
JP2002522431A (ja)	2002-07-23
EP1102762A2 (fr)	2001-05-30
BG105301A (en)	2001-12-29
US6172067B1 (en)	2001-01-09
HRP20010089A2 (en)	2002-02-28
CA2339621A1 (fr)	2000-02-17
MA26659A1 (fr)	2004-12-20
UY25659A1 (es)	2000-02-23
HK1040188A1 (zh)	2002-05-31
ID27212A (id)	2001-03-08
EP1102762B1 (fr)	2002-11-13
PE20000868A1 (es)	2000-08-31
JP3367945B2 (ja)	2003-01-20
AP2001002063A0 (en)	2001-03-31
BR9912778A (pt)	2001-09-25
PA8477701A1 (es)	2000-09-29
YU8201A (sh)	2003-07-07
ZA200100900B (en)	2002-08-28
SK1602001A3 (en)	2002-09-10
WO2000008013A3 (fr)	2000-03-23
CZ2001397A3 (cs)	2002-05-15
CN1317968A (zh)	2001-10-17
NO20010603L (no)	2001-04-05
AR018686A1 (es)	2001-11-28
NO20010603D0 (no)	2001-02-05
WO2000008013A2 (fr)	2000-02-17
DE69903953D1 (de)	2002-12-19
TR200100403T2 (tr)	2001-07-23
AU4385999A (en)	2000-02-28
TNSN99142A1 (fr)	2005-11-10
SV1999000099A (es)	2000-09-05

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IL141029A0 (en)	2002-02-10	2-substituted-1- piperidyl benzimidazole compounds as orl1-receptor agonists
EP1082320A4 (fr)	2001-11-21	Nouveaux composes d'imidazole substitue
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EP1016400A4 (fr)	2001-01-17	Composition pour usage externe
GB9804734D0 (en)	1998-04-29	Compounds
GB9804175D0 (en)	1998-04-22	Compounds
GB9805348D0 (en)	1998-05-06	Compound
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GB9808268D0 (en)	1998-06-17	Compound
GB0015517D0 (en)	2000-08-16	Somatostatin agonists
PL352763A1 (en)	2003-09-08	Somatostatin agonists
IL144355A0 (en)	2002-05-23	5-ht1f agonists
GB9918341D0 (en)	1999-10-06	Hydrometer for house-plants
GB9809823D0 (en)	1998-07-08	Compounds
ZA9710576B (en)	1998-09-16	2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists
GB9809217D0 (en)	1998-07-01	Compounds
GB9823175D0 (en)	1998-12-16	Compound
GB9806697D0 (en)	1998-05-27	Somatostatin agonists
SI1077935T1 (en)	2004-04-30	Phenylsulfonamide-phenylethylamines useful as dopamine receptors
SI1109560T1 (en)	2004-02-29	Compounds useful as aicarft inhibitors
GB9611245D0 (en)	1996-07-31	Benzimidazole compounds
GB9800572D0 (en)	1998-03-11	Heterocyclic compounds
GB9800564D0 (en)	1998-03-11	Heterocyclic compounds
GB9800557D0 (en)	1998-03-11	Heterocyclic compounds