SG50602A1 - Novel heterocyclic compound - Google Patents

Novel heterocyclic compound

Info

Publication number: SG50602A1
Authority: SG; Singapore
Prior art keywords: heterocyclic compound; novel heterocyclic; novel; substituted; hyperalgesic
Prior art date: 1994-01-04

Application number

SG1996006195A

Other languages

English (en)

Inventor

Knud Erik Anderson

Uff Bang Olsen

Petersen

Frederik Christian Gronvald

Ursula Sonnewald

Tine Krogh Jorgensen

Henrik Sune Andersen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-04

Filing date

1995-01-03

Publication date

1998-07-20

1995-01-03 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1998-07-20 Publication of SG50602A1 publication Critical patent/SG50602A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Indole Compounds (AREA)

SG1996006195A 1994-01-04 1995-01-03 Novel heterocyclic compound SG50602A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK1994		1994-01-04
DK129094		1994-11-09

Publications (1)

Publication Number	Publication Date
SG50602A1 true SG50602A1 (en)	1998-07-20

Family

ID=26063135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996006195A SG50602A1 (en)	1994-01-04	1995-01-03	Novel heterocyclic compound

Country Status (31)

Country	Link
US (8)	US5595989A (el)
EP (1)	EP0738262B1 (el)
JP (1)	JP2944221B2 (el)
KR (1)	KR100329450B1 (el)
CN (1)	CN1083431C (el)
AT (1)	ATE191909T1 (el)
AU (1)	AU691858B2 (el)
BG (1)	BG100692A (el)
BR (1)	BR9506452A (el)
CA (1)	CA2180238A1 (el)
CZ (1)	CZ286109B6 (el)
DE (1)	DE69516394T2 (el)
DK (1)	DK0738262T3 (el)
ES (1)	ES2147837T3 (el)
FI (1)	FI114025B (el)
GR (1)	GR3033967T3 (el)
HU (1)	HUT75878A (el)
IL (1)	IL112222A (el)
MY (1)	MY113463A (el)
NO (1)	NO306295B1 (el)
NZ (1)	NZ277763A (el)
PE (1)	PE45095A1 (el)
PL (1)	PL180209B1 (el)
PT (1)	PT738262E (el)
RU (1)	RU2167152C2 (el)
SG (1)	SG50602A1 (el)
SI (1)	SI9520023A (el)
SK (1)	SK88196A3 (el)
TW (1)	TW300887B (el)
UA (1)	UA47396C2 (el)
WO (1)	WO1995018793A1 (el)

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MY113463A (en) *	1994-01-04	2002-03-30	Novo Nordisk As	Novel heterocyclic compounds
US6110913A (en) *	1994-01-04	2000-08-29	Novo Nordisk A/S	N-substituted azaheterocyclic carboxylic acids and esters thereof
US6239148B1 (en) *	1994-01-04	2001-05-29	Novo Nordisk A/S	N-substituted azaheterocyclic carboxylic acids and esters thereof
US5962449A (en)	1995-04-07	1999-10-05	Novo Nordisk A/S	Tricyclic compounds in treating hyperalgesic conditions and NIDDM
US5698551A (en) *	1995-04-07	1997-12-16	Novo Nordisk A/S	Heterocyclic compounds
US5952352A (en) *	1995-04-07	1999-09-14	Novo Nordisk A/S	Heterocyclic compounds
US5716949A (en) *	1995-04-07	1998-02-10	Novo Nordisk A/S	Heterocyclic compounds
UA54385C2 (uk) *	1995-04-07	2003-03-17	Ново Нордіск А/С	N-заміщені азагетероциклічні карбонові кислоти та їх ефіри, спосіб їх одержання, фармацевтична композиція та спосіб лікування
CA2239487A1 (en) *	1995-12-15	1997-06-26	Novo Nordisk A/S	Novel method
US6323206B1 (en)	1996-07-12	2001-11-27	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
ZA978792B (en) *	1996-10-04	1998-04-06	Novo Nordisk As	N-substituted azaheterocyclic compounds.
PL332593A1 (en) *	1996-10-04	1999-09-27	Novo Nordisk As	N-substituted azaheterocyclic compounds
KR20000048899A (ko) *	1996-10-04	2000-07-25	한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느	1,4-디치환 피페라진
US6040318A (en) *	1997-06-25	2000-03-21	Novo Nordisk A/S	Tricycle substituted with azaheterocyclic carboxylic acids
AU749505B2 (en)	1997-10-27	2002-06-27	Dr. Reddy's Laboratories Limited	Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
CN1289336A (zh)	1998-01-21	2001-03-28	千禧药品公司	趋化因子受体拮抗剂和其使用方法
US6613905B1 (en)	1998-01-21	2003-09-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
AU2335699A (en) *	1998-01-21	1999-08-09	Kyowa Hakko Kogyo Co. Ltd.	Chemokine receptor antagonists and methods of use therefor
US6509346B2 (en)	1998-01-21	2003-01-21	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
ES2137136B1 (es) *	1998-05-18	2000-07-01	Esteve Labor Dr	Empleo de derivados de aril (o heteroaril) azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de la inflamacion neurogenica.
US7271176B2 (en) *	1998-09-04	2007-09-18	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use thereof
US6468996B1 (en) *	1998-10-21	2002-10-22	Novo Nordisk A/S	Substituted hetero-polycyclic compounds as PPARα and PPARγ activators
US6207682B1 (en)	1998-12-22	2001-03-27	Novo Nordisk A/S	Modified release formulations containing (R)-1-(10,11-dihydro-5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1propyl)-3-piperidinecarboxylic acid
JP2002532551A (ja) *	1998-12-22	2002-10-02	ノボノルディスクアクティーゼルスカブ	新規製剤
US7355042B2 (en) *	2001-10-16	2008-04-08	Hypnion, Inc.	Treatment of CNS disorders using CNS target modulators
US7541365B2 (en)	2001-11-21	2009-06-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US20040087642A1 (en) *	2002-10-24	2004-05-06	Zeldis Jerome B.	Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain
TWI291467B (en) *	2002-11-13	2007-12-21	Millennium Pharm Inc	CCR1 antagonists and methods of use therefor
WO2004112705A2 (en) *	2003-06-16	2004-12-29	Hypnion, Inc.	Methods for treating sleep disorders
JP2010502621A (ja) *	2006-09-01	2010-01-28	イミユーン・コントロール・インコーポレーテツド	リンパ球の活性化に関連した病気を治療するための新規な組成物および方法
TW201711999A (zh)	2015-09-03	2017-04-01	佛瑪治療公司	﹝６，６﹞稠合雙環組蛋白脫乙醯基酶８（ｈｄａｃ８）抑制劑
US11517557B2 (en)	2017-07-13	2022-12-06	Tonix Pharmaceuticals Holding Corp.	Analogs of cyclobenzaprine and amitriptyline
CN115850232B (zh) *	2023-02-16	2023-05-26	广州佳途科技股份有限公司	一种氟哌噻吨ep杂质h的制备方法及其应用

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MY113463A (en) *	1994-01-04	2002-03-30	Novo Nordisk As	Novel heterocyclic compounds

1994
- 1994-12-30 MY MYPI94003583A patent/MY113463A/en unknown
1995
- 1995-01-02 IL IL11222295A patent/IL112222A/xx not_active IP Right Cessation
- 1995-01-03 PL PL95315294A patent/PL180209B1/pl not_active IP Right Cessation
- 1995-01-03 CN CN95191845A patent/CN1083431C/zh not_active Expired - Fee Related
- 1995-01-03 SI SI9520023A patent/SI9520023A/sl unknown
- 1995-01-03 NZ NZ277763A patent/NZ277763A/en unknown
- 1995-01-03 EP EP95904409A patent/EP0738262B1/en not_active Expired - Lifetime
- 1995-01-03 AT AT95904409T patent/ATE191909T1/de not_active IP Right Cessation
- 1995-01-03 PT PT95904409T patent/PT738262E/pt unknown
- 1995-01-03 DK DK95904409T patent/DK0738262T3/da active
- 1995-01-03 UA UA96072659A patent/UA47396C2/uk unknown
- 1995-01-03 HU HU9601842A patent/HUT75878A/hu unknown
- 1995-01-03 SG SG1996006195A patent/SG50602A1/en unknown
- 1995-01-03 BR BR9506452A patent/BR9506452A/pt not_active IP Right Cessation
- 1995-01-03 DE DE69516394T patent/DE69516394T2/de not_active Expired - Fee Related
- 1995-01-03 ES ES95904409T patent/ES2147837T3/es not_active Expired - Lifetime
- 1995-01-03 CZ CZ19961921A patent/CZ286109B6/cs unknown
- 1995-01-03 KR KR1019960703605A patent/KR100329450B1/ko not_active Expired - Fee Related
- 1995-01-03 WO PCT/DK1995/000002 patent/WO1995018793A1/en not_active Ceased
- 1995-01-03 JP JP7518275A patent/JP2944221B2/ja not_active Expired - Fee Related
- 1995-01-03 CA CA002180238A patent/CA2180238A1/en not_active Abandoned
- 1995-01-03 US US08/367,648 patent/US5595989A/en not_active Expired - Fee Related
- 1995-01-03 SK SK881-96A patent/SK88196A3/sk unknown
- 1995-01-03 AU AU13110/95A patent/AU691858B2/en not_active Ceased
- 1995-01-03 RU RU96116134/04A patent/RU2167152C2/ru not_active IP Right Cessation
- 1995-01-04 PE PE1995258527A patent/PE45095A1/es not_active Application Discontinuation
- 1995-02-22 TW TW084101613A patent/TW300887B/zh active
- 1995-05-18 US US08/444,140 patent/US5688788A/en not_active Expired - Fee Related
- 1995-10-18 US US08/544,500 patent/US5721254A/en not_active Expired - Fee Related
- 1995-10-18 US US08/544,502 patent/US5693649A/en not_active Expired - Fee Related
- 1995-10-18 US US08/544,682 patent/US5795888A/en not_active Expired - Fee Related
- 1995-10-18 US US08/544,905 patent/US5712292A/en not_active Expired - Fee Related
1996
- 1996-03-27 US US08/626,745 patent/US5668129A/en not_active Expired - Fee Related
- 1996-07-02 BG BG100692A patent/BG100692A/xx unknown
- 1996-07-03 NO NO962811A patent/NO306295B1/no not_active IP Right Cessation
- 1996-07-04 FI FI962749A patent/FI114025B/fi active
1998
- 1998-01-23 US US09/012,918 patent/US6043239A/en not_active Expired - Fee Related
2000
- 2000-07-17 GR GR20000401652T patent/GR3033967T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0738262B1 (en)	2000-04-19
GR3033967T3 (en)	2000-11-30
NO962811L (no)	1996-09-04
UA47396C2 (uk)	2002-07-15
HU9601842D0 (en)	1996-09-30
PL180209B1 (pl)	2001-01-31
MY113463A (en)	2002-03-30
SK88196A3 (en)	1997-06-04
PE45095A1 (es)	1995-12-18
SI9520023A (en)	1997-04-30
CN1142226A (zh)	1997-02-05
BG100692A (en)	1997-09-30
US5795888A (en)	1998-08-18
WO1995018793A1 (en)	1995-07-13
RU2167152C2 (ru)	2001-05-20
FI114025B (fi)	2004-07-30
TW300887B (el)	1997-03-21
US5595989A (en)	1997-01-21
ATE191909T1 (de)	2000-05-15
DK0738262T3 (da)	2000-09-04
CZ192196A3 (en)	1997-05-14
FI962749L (fi)	1996-09-04
CZ286109B6 (cs)	2000-01-12
DE69516394D1 (de)	2000-05-25
US5693649A (en)	1997-12-02
NZ277763A (en)	2001-11-30
ES2147837T3 (es)	2000-10-01
FI962749A0 (fi)	1996-07-04
AU1311095A (en)	1995-08-01
EP0738262A1 (en)	1996-10-23
US5721254A (en)	1998-02-24
CA2180238A1 (en)	1995-07-13
US5668129A (en)	1997-09-16
US5688788A (en)	1997-11-18
CN1083431C (zh)	2002-04-24
NO306295B1 (no)	1999-10-18
IL112222A0 (en)	1995-03-30
IL112222A (en)	1999-12-31
BR9506452A (pt)	1997-09-02
HUT75878A (en)	1997-05-28
US5712292A (en)	1998-01-27
AU691858B2 (en)	1998-05-28
KR100329450B1 (ko)	2002-10-04
JPH09507239A (ja)	1997-07-22
DE69516394T2 (de)	2000-10-26
JP2944221B2 (ja)	1999-08-30
PT738262E (pt)	2000-10-31
US6043239A (en)	2000-03-28
NO962811D0 (no)	1996-07-03

Publication	Publication Date	Title
SG50602A1 (en)	1998-07-20	Novel heterocyclic compound
MX9707531A (es)	1997-11-29	Nuevos compuestos heterociclicos.
WO2000021927A3 (en)	2000-07-13	Pyrrole-2,5-diones as gsk-3 inhibitors
EA200400944A1 (ru)	2005-04-28	Замещенные производные тетрациклина, фармацевтическая композиция и способ лечения субъекта с их использованием
AP9701039A0 (en)	1997-07-31	Derivatives of 2- (2-oxo-ethlidene)-imidazolidin-4-one.
EA200201271A1 (ru)	2003-04-24	Ингибиторы 11-бета-гидроксистероиддегидрогеназы типа 1
NZ334186A (en)	2000-09-29	Neurotrophic heterocyclic esters and amides with an affinity to FKBP-type immunophilins
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