SE0301119D0 - New non-ionic surfactants for solubilizing poorly soluble molecules - Google Patents
New non-ionic surfactants for solubilizing poorly soluble moleculesInfo
- Publication number
- SE0301119D0 SE0301119D0 SE0301119A SE0301119A SE0301119D0 SE 0301119 D0 SE0301119 D0 SE 0301119D0 SE 0301119 A SE0301119 A SE 0301119A SE 0301119 A SE0301119 A SE 0301119A SE 0301119 D0 SE0301119 D0 SE 0301119D0
- Authority
- SE
- Sweden
- Prior art keywords
- ionic surfactants
- new non
- fatty acid
- polyoxyalkylene
- poorly soluble
- Prior art date
Links
- 239000002736 nonionic surfactant Substances 0.000 title abstract 2
- 230000003381 solubilizing effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- -1 hydroxy fatty acid Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
- C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyethers (AREA)
- Enzymes And Modification Thereof (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301119A SE0301119D0 (sv) | 2003-04-14 | 2003-04-14 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| JP2006508018A JP4589917B2 (ja) | 2003-04-14 | 2004-04-13 | 低可溶性分子を可溶化するための新しい非イオン性界面活性剤 |
| NZ542752A NZ542752A (en) | 2003-04-14 | 2004-04-13 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| AU2004228602A AU2004228602B2 (en) | 2003-04-14 | 2004-04-13 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| EP04727166.3A EP1615874B1 (en) | 2003-04-14 | 2004-04-13 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| KR1020057019461A KR101091324B1 (ko) | 2003-04-14 | 2004-04-13 | 용해성이 불량한 분자를 가용화하기 위한 신규 비이온계계면활성제 |
| PCT/SE2004/000572 WO2004089869A1 (en) | 2003-04-14 | 2004-04-13 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| MXPA05010893A MXPA05010893A (es) | 2003-04-14 | 2004-04-13 | Nuevos agentes tensioactivos no ionicos para solubilizar moleculas pobremente solubles. |
| US10/553,275 US7491836B2 (en) | 2003-04-14 | 2004-04-13 | Non-ionic surfactants for poorly soluble molecules |
| HK06110149.3A HK1089747B (en) | 2003-04-14 | 2004-04-13 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| BRPI0408972-3A BRPI0408972A (pt) | 2003-04-14 | 2004-04-13 | composto, formulação, uso de um composto, e, processo para a preparação de um éster de polioxialquileno glicol |
| CA2521612A CA2521612C (en) | 2003-04-14 | 2004-04-13 | Non-ionic surfactant comprising polyoxyalkylene glycol hydroxy fatty acid derivatives for solubilizing poorly soluble molecules |
| ES04727166.3T ES2445821T3 (es) | 2003-04-14 | 2004-04-13 | Nuevos tensoactivos no iónicos para solubilizar moléculas pobremente solubles |
| CN2004800098771A CN1774414B (zh) | 2003-04-14 | 2004-04-13 | 用于溶解可溶性差的分子的新型非离子表面活性剂 |
| IL171058A IL171058A (en) | 2003-04-14 | 2005-09-22 | Polyoxyalkylene glycols or esterified monoalkylated polyoxyalkylene glycols, formulations comprising them and use thereof as surfactants and in the preparation of formulations including pharmaceutical formulations |
| ZA200508247A ZA200508247B (en) | 2003-04-14 | 2005-10-12 | New non-ionic surfactants for solubilizing poorly soluble molecules |
| NO20055331A NO20055331L (no) | 2003-04-14 | 2005-11-11 | Nye ikke-ioniske overflateaktive stoffer for a opplose darlig loselige molekyler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301119A SE0301119D0 (sv) | 2003-04-14 | 2003-04-14 | New non-ionic surfactants for solubilizing poorly soluble molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0301119D0 true SE0301119D0 (sv) | 2003-04-14 |
Family
ID=20291043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0301119A SE0301119D0 (sv) | 2003-04-14 | 2003-04-14 | New non-ionic surfactants for solubilizing poorly soluble molecules |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7491836B2 (xx) |
| EP (1) | EP1615874B1 (xx) |
| JP (1) | JP4589917B2 (xx) |
| KR (1) | KR101091324B1 (xx) |
| CN (1) | CN1774414B (xx) |
| AU (1) | AU2004228602B2 (xx) |
| BR (1) | BRPI0408972A (xx) |
| CA (1) | CA2521612C (xx) |
| ES (1) | ES2445821T3 (xx) |
| IL (1) | IL171058A (xx) |
| MX (1) | MXPA05010893A (xx) |
| NO (1) | NO20055331L (xx) |
| NZ (1) | NZ542752A (xx) |
| SE (1) | SE0301119D0 (xx) |
| WO (1) | WO2004089869A1 (xx) |
| ZA (1) | ZA200508247B (xx) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090280429A1 (en) * | 2008-05-08 | 2009-11-12 | Xerox Corporation | Polyester synthesis |
| GB201115634D0 (en) * | 2011-09-09 | 2011-10-26 | Univ Liverpool | Compositions of lopinavir |
| WO2013166431A1 (en) | 2012-05-03 | 2013-11-07 | Beth Isreal Deaconess Medical Center, Inc. | Lipids that increase insulin sensitivity and methods of using the same |
| EP2972399B1 (en) | 2013-03-15 | 2020-09-02 | Beth Israel Deaconess Medical Center, Inc. | Lipids that increase insulin sensitivity and methods of using the same |
| US9284583B2 (en) * | 2014-07-16 | 2016-03-15 | Eastman Chemical Company | Enzyme-catalyzed polyoxyalkylene esters |
| US11013711B2 (en) | 2016-06-10 | 2021-05-25 | Beth Israel Deaconess Medical Center, Inc. | Fatty acid esters of hydroxy fatty acids (FAHFAs) for use in the treatment of type 1 diabetes |
| CN107664676A (zh) * | 2016-07-29 | 2018-02-06 | 中国石油化工股份有限公司 | 基于增粘型乳液增溶水速率分析方法 |
| EP3820928A1 (en) * | 2018-09-05 | 2021-05-19 | Lonza Guangzhou Nansha Ltd. | Method for making polyoxyethylene 1,4 sorbitan fatty acid ester |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2911241A1 (de) * | 1979-03-22 | 1980-10-02 | Basf Ag | Alkoxylierte fettsaeuren, verfahren zu deren herstellung und ihre anwendung als loesungsvermittler |
| JPS5969135A (ja) | 1982-10-12 | 1984-04-19 | Nippon Oil & Fats Co Ltd | 可溶化または乳化剤 |
| JPS61187795A (ja) * | 1985-02-15 | 1986-08-21 | Dai Ichi Kogyo Seiyaku Co Ltd | ポリグリセリン脂肪酸エステルの製造法 |
| KR970704464A (ko) * | 1994-11-03 | 1997-09-06 | 가이슐러 에리히, 데커 카를-루드빅 | 간단한 조성 및 높은 생물 유효성을 갖는 경구 투여용의 신규 사이클로스포린 제형 및 이의 제조방법(Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability, and process for producing them) |
| JP3533043B2 (ja) * | 1995-06-19 | 2004-05-31 | 三菱化学株式会社 | ポリグリセリン脂肪酸エステルの曇点測定方法、該方法を用いる物性評価及び製造方法。 |
| FR2746106B1 (fr) * | 1996-03-15 | 1998-08-28 | Combustible emulsionne et l'un de ses procedes d'obtention | |
| JP3610509B2 (ja) * | 1996-03-26 | 2005-01-12 | サンノプコ株式会社 | 消泡剤 |
| DE19622214C2 (de) * | 1996-06-03 | 2000-09-28 | Cognis Deutschland Gmbh | Verwendung von Hydroxycarbonsäureestern |
| DE19851777A1 (de) * | 1998-11-10 | 2000-05-11 | Basf Ag | Verwendung von Estern oder Amiden hydroxylierter Carbonsäuren als Solubilisatoren |
-
2003
- 2003-04-14 SE SE0301119A patent/SE0301119D0/xx not_active Application Discontinuation
-
2004
- 2004-04-13 NZ NZ542752A patent/NZ542752A/en not_active IP Right Cessation
- 2004-04-13 EP EP04727166.3A patent/EP1615874B1/en not_active Expired - Lifetime
- 2004-04-13 CA CA2521612A patent/CA2521612C/en not_active Expired - Fee Related
- 2004-04-13 AU AU2004228602A patent/AU2004228602B2/en not_active Ceased
- 2004-04-13 US US10/553,275 patent/US7491836B2/en not_active Expired - Lifetime
- 2004-04-13 KR KR1020057019461A patent/KR101091324B1/ko not_active Expired - Fee Related
- 2004-04-13 ES ES04727166.3T patent/ES2445821T3/es not_active Expired - Lifetime
- 2004-04-13 CN CN2004800098771A patent/CN1774414B/zh not_active Expired - Lifetime
- 2004-04-13 MX MXPA05010893A patent/MXPA05010893A/es active IP Right Grant
- 2004-04-13 BR BRPI0408972-3A patent/BRPI0408972A/pt not_active IP Right Cessation
- 2004-04-13 JP JP2006508018A patent/JP4589917B2/ja not_active Expired - Lifetime
- 2004-04-13 WO PCT/SE2004/000572 patent/WO2004089869A1/en not_active Ceased
-
2005
- 2005-09-22 IL IL171058A patent/IL171058A/en not_active IP Right Cessation
- 2005-10-12 ZA ZA200508247A patent/ZA200508247B/en unknown
- 2005-11-11 NO NO20055331A patent/NO20055331L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL171058A (en) | 2011-04-28 |
| CA2521612A1 (en) | 2004-10-21 |
| CA2521612C (en) | 2012-02-07 |
| NZ542752A (en) | 2007-05-31 |
| AU2004228602B2 (en) | 2007-06-14 |
| US20060287542A1 (en) | 2006-12-21 |
| HK1089747A1 (en) | 2006-12-08 |
| NO20055331D0 (no) | 2005-11-11 |
| KR101091324B1 (ko) | 2011-12-07 |
| KR20060004937A (ko) | 2006-01-16 |
| US7491836B2 (en) | 2009-02-17 |
| CN1774414B (zh) | 2010-12-08 |
| EP1615874B1 (en) | 2013-12-25 |
| JP2006526048A (ja) | 2006-11-16 |
| BRPI0408972A (pt) | 2006-04-04 |
| WO2004089869A1 (en) | 2004-10-21 |
| CN1774414A (zh) | 2006-05-17 |
| NO20055331L (no) | 2006-01-16 |
| MXPA05010893A (es) | 2005-11-25 |
| JP4589917B2 (ja) | 2010-12-01 |
| EP1615874A1 (en) | 2006-01-18 |
| ES2445821T3 (es) | 2014-03-05 |
| AU2004228602A1 (en) | 2004-10-21 |
| ZA200508247B (en) | 2007-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |