RU2423888C1 - Adaptogenic action beverage - Google Patents

Abstract

FIELD: food industry.

SUBSTANCE: adaptogenic action beverage contains (per 100 decalitres of beverage) an adaptogenic remedy consisting of 15-25 kg of natural honey, 0.15-0.25 kg of refined amberat extract dissolved in water and 90 kg of rosehips syrup. Additionally the beverage contains 1.0-1.5 kg of citric acid, 90-200 kg of a flavour additive, 0.150-0.177 kg of sodium benzoate; the rest is carbonated water or non-carbonated water. The ratio of amberat extract to water 1:8. The flavour additive may be represented by berry and/or fruit and/or herb syrup. The herb syrup may be represented by estragon syrup, the berry syrup - by a syrup of raspberry and/or red bilberry and/or blueberry and/or cranberry and/or cherry. The amberat extract may by applied in the form of dry powder.

EFFECT: production of a beverage which has high organoleptic properties and varied taste qualities; the beverage has a high adaptogenic action and vitamin effect; the beverage may be consumed by people of all age groups and has a low cost.

3 tbl, 4 ex

Description

The invention relates to the food industry, namely to the production of soft drinks that increase the nonspecific resistance of the body.

In recent years, there has been a significant decrease in health indicators and an increase in the morbidity of the population due to a number of objective reasons, among which a sharp deterioration of the environmental situation, an intensification of the rhythm of life and a decrease in the level of social protection of the general population are important. a decrease in body resistance associated with a weakening of detoxification, immune and other adaptive adaptations body mechanisms. Under these conditions, the implementation of preventive measures, with the aim of increasing the nonspecific resistance of the body, becomes particularly relevant. One of the methods for solving this kind of problem, in addition to using medications specially designed for these purposes, often accompanied by serious side effects, is to expand the practice of the population consuming food products, including beverages, which have adaptogenic activity and increase the body's resistance to a wide range of aggressive environmental factors Wednesday.

The prior art drinks with adaptogenic action.

So, from the description of the certificate of authorship No. 1450813 (IPC 4: A23L 2/00, published January 15, 1989), a concentrate for the preparation of a diet drink with adaptogenic effect is known, which contains the following components, wt.%:

Concentrated grape juice 35-45 Wild Apple Variety Extract 25-35 Chokeberry Extract 14-16 Rosehip extract 8-12 Hawthorn extract 4-6

Also, from the RF patent No. 2123270 (IPC 7: A23L 2/00, published December 20, 1998), a non-alcoholic beverage is known containing per 100 gave the finished product: 79.0-91.2 kg of sugar, 3.0-7.0 kg of lemon acid, 2.0 kg of oregano, 2.0 kg of St. John's wort, 2.0 kg of peppermint, 2.0 kg of thyme, 2.0 kg of linden flowers, 1.0-2.0 kg of adaptogenic agent (PADM) - adaptogenic food medical additives and soda. Adaptogenic food supplement is a water-alcohol mixture of 45%, which includes homeopathic medicines of plant and animal origin.

In addition, from the RF patent No. 2034506 (IPC 6: A23L 2/00, published May 10, 1995), a non-alcoholic beverage with adaptogenic properties is known which contains the following components, in kg / 100 gave the finished drink: sugar 100-150; aromatic emulsion "Pineapple" 70,050 1.0-2.0; citric acid 1.0-1.76; and also (in l): sea buckthorn juice 2.0-4.0; water-alcohol extract of the roots and rhizomes of elecampane 0.1-0.15; water decoction of the roots and rhizomes of licorice 0.5-1.5 and water - the rest.

The disadvantages of the known drinks is that they contain a significant amount of sugar used in production, which leads to high calorie drinks. In addition, the disadvantages of known drinks is the use of alcohol-containing components and herbs with tonic properties, which can cause unwanted effects in the form of increased irritability, irritation of the gastric mucosa, insomnia, and allergic reactions. Reception of such drinks is undesirable for children.

In this regard, the urgent problem is the development of new tools and products that have adaptogenic activity and stimulate the body's defenses that can be used by people of any age. A promising direction in this regard is the use of drinks from raw materials of natural origin, developed on the basis of the experience of traditional medicine of peoples of different regions of the world.

The technical result of the present invention is to obtain funds with high organoleptic properties, with high adaptogenic and vitamin action, which can be used by any age group. Also patented drink has a lower cost. In addition, the claimed technical solution makes it possible to obtain drinks with different taste qualities.

The claimed technical result is achieved through the use of a drink with adaptogenic action, which contains citric acid, carbonated or non-carbonated water, a flavoring additive, sodium benzoate and adaptogenic agent consisting of natural honey, water-soluble extract of mummy and rosehip syrup, in the following ratio of components per 100 gave a drink:

Natural honey 15-25 kg Rosehip Syrup 90 kg Lemon acid 1.0-1.5 kg Purified mumiye extract dissolved in water 0.15-0.25 kg while the ratio of mummy extract to water is 1: 8 Sodium benzoate 0.150-0.177 kg Flavoring additive 90-200 kg Water Rest

As a flavoring additive, the drink may contain berry, and / or fruit, and / or herbal syrup, in particular syrup, rose hips, raspberries, cherries, milk thistle, tarragon, sea buckthorn, lemon, lime, as well as tea extract, matcha tea, green tea.

As an extract of the mummy, used as one of the components of the detoxifying mixture, a dry mummy extract of high purity can be used.

Mumiye dry extract contains micro and macro elements (cobalt, nickel, copper, zinc, manganese, chromium, iron, sodium, potassium, magnesium), humic acids, polyphenolic compounds, amino acids, steroids, phospholipids.

Immediately before the preparation of the drink, the dry mummy extract is dissolved in water in a ratio of 1: 8 (1 part mummy and 8 parts water).

Thanks to the use of the purified extract, the mummy achieves 100% solubility in water in the selected ratio without the formation of sediment during further storage of the drink.

Mummy is used as a restorative and tonic, replacing multivitamins and trace elements.

Mumiye has almost no side effects, except in cases of individual intolerance when used in excessive doses.

In order to activate the antitoxic effect of non-oxidized compounds of phenolic nature and to prevent their free spontaneous oxidation, ascorbic acid contained in rosehip syrup is included in the composition of the alkoprotective mixture. In addition, the use of rosehip syrup in the drink leads to the stabilization of the mummy dissolved in water due to the content of natural ascorbic acid in the syrup.

Also, due to the content of vitamins C and P, flavonoids, carotenoids, tannins, pectins in rosehip syrup, it has a general strengthening effect on the body, stimulates its resistance, enhances tissue regeneration, reduces vascular permeability, takes part in carbohydrate and mineral metabolism, and has anti-inflammatory properties.

Honey is a source of vitamins, glucose and sucrose.

The use of honey in the composition of the drink has a positive effect on the therapeutic and prophylactic effect of this drink, and also improves its taste and aroma.

So, a mixture of natural honey and mummy contains (t / 100 g): water 23.8, protein 0.77, fat 0.23, carbohydrates 74.0, ash 0.26, the energy value of the product is 300 kcal .

The content of proteins in the detoxifying mixture and the high calorie content of honey in the presence of this combination of proteins contribute to the easy digestibility of the drink, creates the optimal concentration of the most important proteins and vitamins in the body, promotes digestion and assimilation of food, which is important for alcohol intoxication.

Due to the high content of amino acids, flavonoids, and sterols in the mummy, an adaptogenic effect is provided. The drink increases the body's degree of adaptation to extreme conditions and stress.

The process of preparing a patentable beverage includes the following main technological stages:

- water treatment;

- preparation of an aqueous solution of mummy;

- preparation of blend syrup;

- bottling, clogging;

- storage and transportation.

Water treatment is carried out in accordance with the requirements of GOST R 51232-98.

Mumiye extract (Shilajit) in the amount of 0.15-0.25 kg is dissolved with stirring in water in a ratio of 1: 8. The obtained aqueous mummy solution is added to the blending tank and 100 l of water are added. After that, honey is added to the blending tank with constant stirring and the calculated amount of rosehip syrup is added. After that, pre-dissolved citric acid and sodium benzoate are introduced into the blending tank. By adding water, the volume of the drink is adjusted to 1000 l. All components are mixed for 15-20 minutes, after which they are left for 30 minutes for better assimilation of the aromatic substances of the blend, suppression of the growth of microorganisms by the preservative, and also for the possible isolation of insoluble components and colloidal particles in the sediment. After checking the physico-chemical and organoleptic characteristics, the drink is filtered and sent for bottling.

The invention is further illustrated by the following examples of specific beverage compositions, kg per 100 gave:

Example 1

Natural honey 15 kg Lemon acid 1,0 kg Mumiye extract dissolved in water 0.15 (the ratio of mummy extract to water was 1: 8) Sodium benzoate 0.150 kg Rosehip Syrup 90 kg Flavoring additive (tarragon syrup) 90 kg Sparkling water Rest

Example 2

Natural honey 25 kg Lemon acid 1,5 kg Mumiye extract dissolved in water 0.25 (ratio of mummy extract to water 1: 8) Sodium benzoate 0.177 kg Rosehip Syrup 115 kg Cherry Syrup 100 kg Sparkling water Rest

Example 3

Natural honey 20 kg Lemon acid 1.3 kg Mumiye extract dissolved in water 0.25 (ratio of mummy extract to water 1: 8) Sodium benzoate 0.150 kg Rosehip Syrup 100 kg Syrup tarragon 120 kg Still water Rest

Example 4

Natural honey 18 kg Lemon acid 1.1 kg Mumiye extract dissolved in water 0.18 (ratio of mummy extract to water 1: 8) Sodium benzoate 0.160 kg Rosehip Syrup 50 kg Cherry Syrup 100 kg Still water Rest

Due to the selected composition of the components, the resulting drink has a high adaptogenic effect, which was proved by preclinical trials of drinks prepared in accordance with the examples carried out by the Institute of General and Experimental Biology SB RAS.

The experiments were carried out on mice of the CBA line of both sexes weighing 18-20 g. Hypobaric hypoxia was reproduced by the generally accepted method in a special pressure chamber, in which using an oil pump a vacuum was created corresponding to the "rise" of animals to a certain height. "Rise" was carried out at a speed of 20 m / min to a height of 6000 m (atm. Pressure - 354.2 mm Hg, partial oxygen tension - 76 mm Hg). At this altitude, the "rise" ceased for 2 minutes (platform). Then, at the same speed, they “climbed” further to a height of 10,000 m (atm. Pressure — 196.8 mm Hg, partial oxygen tension — 50 mm Hg). The “drink” was administered to animals intragastrically in a volume of 1.0 ml / 100 g once 1 hour before testing, and also repeatedly in the indicated volume for 7 days once a day 1 hour before a meal. The animals of the control group were intragastrically injected with a similar volume of distilled water. The resistance of animals to the action of hypobaric hypoxia was determined by the life expectancy of animals at an altitude of 10,000 m. The data obtained are shown in table 1.

Table 1 The effect of "Drink" on the life span of white mice with hypobaric hypoxia Groups Life span, min with a single injection (n = 8) with repeated administration (n = 8) Control 4.94 ± 0.48 5.52 ± 0.62 Drink 8.20 ± 0.85 * 20.40 ± 2.36 *

As follows from the data given in table 1, a single injection of a drink in a volume of 1.0 ml / 100 g against the background of hypobaric hypoxia is accompanied by an increase in life expectancy of mice by an average of 67% compared with data from animals in the control group. A more pronounced antihypoxic effect was established with repeated administration of the test drug: the life expectancy of animals of the experimental group increased by an average of 3.5 times in comparison with the control. At the same time, some of the animals that received the drink many times survived under conditions of rarefaction of air, corresponding to a rise of 10,000 m above sea level.

Next, the effect of the drink on resistance to tissue hypoxia was determined.

The experiments were carried out on mice of a CBA line of both sexes weighing 18-20 g. A tissue hypoxia model was created by intraperitoneal injection of 2 g / kg aqueous solution of lead acetate into animals. The drink was administered intragastrically in a volume of 1.0 ml / 100 g once 1 hour before testing, and also repeatedly in the indicated volume for 7 days once a day 1 hour before a meal. The animals of the control group were intragastrically injected with a similar volume of distilled water. The resistance of animals to the effects of tissue hypoxia was determined by the life time of animals from the moment of introduction of the poison to the cessation of respiration. The data obtained are shown in table 2.

table 2 The effect of "Drink" on the life expectancy of white mice with tissue hypoxia Groups Life span, min with a single injection (n = 6) with repeated administration (n = 6) Control 103.3 ± 8.58 110.5 ± 9.6 Drink 111.6 ± 6.10 138.2 ± 12.0 *

The data shown in table 2 indicate that with a single injection of “Drink” in the indicated volume, a tendency to increase the life expectancy of mice with tissue hypoxia induced by lead acetate is noted, while repeated administration of the test agent is accompanied by an increase in the resistance of animals to tissue hypoxia, as indicates an increase in life expectancy of mice of the experimental group by an average of 25% compared with similar indicators of animals of the control group.

Thus, the obtained data indicate that the drink in the volume of 1.0 ml / 100 g has a pronounced antihypoxic activity, increasing the lifespan of animals with hypobaric and tissue hypoxia. Moreover, the test agent has a more significant antihypoxic effect in relation to hypobaric hypoxia.

Next, tests were conducted related to the influence of the drink on the body's resistance to immobilization stress.

The experiments were carried out on Wistar rats of both sexes weighing 160-180 g. The model of immobilization stress was reproduced by the conventional method by fixing the animals in the supine position for 24 hours. The rats of the experimental group were intragastrically administered “Drink” in a volume of 1.0 ml / 100 g once 1 hour before stress exposure. Animals of the control group received an equivolume amount of distilled water. After 24 hours, the animals were decapitated under mild ether anesthesia and the weight of the adrenal glands, thymus, and the number of ulcerative lesions in the gastric mucosa were determined. The data obtained are shown in table 3.

Table 3 The effect of "Drink" on the severity of stress damage to organs in white rats on the background of immobilization stress Groups of animals Weight / mg / 100 g (n = 6) The amount of hemorrhage in the stomach adrenal glands thymus Intact 16.6 ± 0.8 150.6 ± 11.0 0 Control 25.2 ± 1.3 94.4 ± 7.5 7.1 ± 0.5 Drink 19.4 ± 1.0 * 136.2 ± 0.2 * 1.6 ± 0.6 *

As can be seen from table 3, as a result of 24-hour immobilization in animals, a characteristic picture of the stress response develops, the so-called “Selye triad”, which is expressed in catabolic changes on the part of internal organs: significant hypertrophy of the adrenal glands, involution of the thymus and the appearance of hemorrhages in the gastric mucosa. Prophylactic single administration of “Drink” in the indicated volume had a pronounced stress-protective effect. This was evidenced by a decrease in the degree of adrenal hypertrophy: an average of 25% compared with the control; slight involution of the thymus: the mass of this organ in animals of the experimental group was 44% more compared to the control; in the gastric mucosa of rats of the experimental group there were only single point hemorrhages, while in animals of the control group hemorrhages were almost 5 times more.

The data obtained indicate that the patented drink in a volume of 1.0 ml / 100 g exerts a pronounced anti-stress effect, preventing the development of catabolic changes in the internal organs of animals during immobilization stress.

Thus, experimental studies of a patented drink containing a mixture of mummy extract, rosehip syrup and honey as an adaptogenic agent showed that it has a pronounced adaptogenic effect, increasing the body's resistance to extreme factors of various nature. Thus, the introduction of a test drink to laboratory animals increases the body's resistance to the effects of hypobaric and tissue hypoxia, tetrachlomethane intoxication and immobilization stress. It has been reliably established that the most pronounced adaptogenic effect of the test drug is observed with its multiple prophylactic administration.

The expressed adaptogenic properties of the drink argue the feasibility of its use by wide layers of the population to increase mental and physical performance; prevention of fatigue with increased mental and physical stress; for use by persons employed in industries with harmful working conditions; to increase resistance to infections; with asthenic conditions, as well as during rehabilitation after serious illnesses.

Claims (5)

1. A drink with adaptogenic effect, containing citric acid, carbonated or non-carbonated water, a flavoring additive, sodium benzoate and adaptogenic agent consisting of a mixture of natural honey, a water-soluble extract of mummy and rosehip syrup, in the following ratio of the starting components per 100 gave the drink:
natural honey 15-25 kg rosehip syrup 90 kg lemon acid 1.0-1.5 kg purified in water mummy extract 0.15-0.25 kg
while the ratio of mummy extract to water is 1: 8,
sodium benzoate 0.150-0.177 kg flavoring additive 90-200 kg water rest 2. The drink according to claim 1, characterized in that as a flavoring additive used berry, and / or fruit, and / or herbal syrup. 3. The drink according to claim 2, characterized in that the raspberry and / or lingonberry and / or blueberry and / or cranberry and / or cherry syrup is used as berry syrup. 4. The drink according to claim 2, characterized in that tarragon syrup is used as a herbal syrup. 5. The drink according to claim 1, characterized in that as the extract of the mummy use dry powder of the extract of the mummy.