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RU2409349C2 - Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1) - Google Patents

Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1) Download PDF

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Publication number
RU2409349C2
RU2409349C2 RU2008144965/15A RU2008144965A RU2409349C2 RU 2409349 C2 RU2409349 C2 RU 2409349C2 RU 2008144965/15 A RU2008144965/15 A RU 2008144965/15A RU 2008144965 A RU2008144965 A RU 2008144965A RU 2409349 C2 RU2409349 C2 RU 2409349C2
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RU
Russia
Prior art keywords
glp
fdkp
diketopiperazine
solution
specified
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RU2008144965/15A
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English (en)
Russian (ru)
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RU2008144965A (ru
Inventor
Стефани ГРИН (US)
Стефани ГРИН
Дэвид БРАНДТ (US)
Дэвид БРАНДТ
Кохава ГЕЛЬБЕР (US)
Кохава ГЕЛЬБЕР
Марк КИНГ (US)
Марк КИНГ
Вэйман Вэнделл ЧИЗАМ (US)
Вэйман Вэнделл ЧИЗАМ
Кит ОБЕРГ (US)
Кит ОБЕРГ
Андреа ЛЕОНЕ-БЭЙ (US)
Андреа ЛЕОНЕ-БЭЙ
Марк Дж. ХОУКЕНСОН (US)
Марк Дж. ХОУКЕНСОН
Мэри ФЕЙРИС (US)
Мэри Фейрис
Original Assignee
Маннкайнд Корпорейшн
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Publication of RU2008144965A publication Critical patent/RU2008144965A/ru
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Publication of RU2409349C2 publication Critical patent/RU2409349C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
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    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
RU2008144965/15A 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1) RU2409349C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74488206P 2006-04-14 2006-04-14
US60/744,882 2006-04-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2010137392/15A Division RU2542500C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)

Publications (2)

Publication Number Publication Date
RU2008144965A RU2008144965A (ru) 2010-05-20
RU2409349C2 true RU2409349C2 (ru) 2011-01-20

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ID=38567214

Family Applications (3)

Application Number Title Priority Date Filing Date
RU2008144965/15A RU2409349C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагонподобный пептид(glp-1)
RU2010137392/15A RU2542500C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)
RU2014152320A RU2014152320A (ru) 2006-04-14 2014-12-23 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)

Family Applications After (2)

Application Number Title Priority Date Filing Date
RU2010137392/15A RU2542500C2 (ru) 2006-04-14 2007-04-16 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)
RU2014152320A RU2014152320A (ru) 2006-04-14 2014-12-23 Фармацевтические композиции, содержащие глюкагон-подобный пептид 1 (glp-1)

Country Status (11)

Country Link
EP (1) EP2010155A2 (fr)
JP (3) JP5415938B2 (fr)
KR (3) KR20150042304A (fr)
CN (2) CN101453988A (fr)
AU (1) AU2007238000B2 (fr)
BR (1) BRPI0709964A2 (fr)
CA (1) CA2646400A1 (fr)
HK (1) HK1206241A1 (fr)
MX (1) MX2008013216A (fr)
RU (3) RU2409349C2 (fr)
WO (1) WO2007121411A2 (fr)

Cited By (2)

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US9764003B2 (en) 2012-07-01 2017-09-19 Novo Nordisk A/S Use of long-acting GLP-1 peptides
US12029779B2 (en) 2017-10-12 2024-07-09 Novo Nordisk A/S Semaglutide in medical therapy

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UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
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AU2007238000B2 (en) 2013-01-17
RU2542500C2 (ru) 2015-02-20
CN101453988A (zh) 2009-06-10
CA2646400A1 (fr) 2007-10-25
AU2007238000A1 (en) 2007-10-25
KR20150042304A (ko) 2015-04-20
RU2008144965A (ru) 2010-05-20
CN104288756A (zh) 2015-01-21
KR20080111533A (ko) 2008-12-23
BRPI0709964A2 (pt) 2011-08-02
RU2014152320A (ru) 2016-07-20
WO2007121411A2 (fr) 2007-10-25
MX2008013216A (es) 2008-10-27
RU2010137392A (ru) 2012-03-20
JP5898156B2 (ja) 2016-04-06
WO2007121411A3 (fr) 2007-12-13
JP5415938B2 (ja) 2014-02-12
KR101438839B1 (ko) 2014-10-02
JP2014043445A (ja) 2014-03-13
EP2010155A2 (fr) 2009-01-07
JP2016104736A (ja) 2016-06-09

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