RU2276989C1 - Method for treating the cases of agricultural young animals dyspepsia - Google Patents

Abstract

FIELD: veterinary medicine.

SUBSTANCE: method involves introducing alcohol-honey extract of milky-wax ripe walnut with farina and glycine added to unit dose liquid twice a day during 6 days at a dose of 0.5 ml per 1 kg of animal weight.

EFFECT: enhanced effectiveness of treatment; accelerated treatment course.

1 tbl

Description

The invention relates to animal husbandry and can be used to treat dyspepsia of farm animals.

The most acute problem of modern animal husbandry is the disease of young animals.

Most diseases of the digestive system in young farm animals (more than 85%) are classified by non-communicable pathology as official statistics.

However, in recent years, numerous studies in our country and abroad have established that these diseases against the background of adverse effects on animals of various predisposing factors that reduce the general nonspecific resistance of the body, have an infectious nature.

The use of antibiotics and other synthetic drugs in such cases does not give the expected effect due to the appearance of a huge number of pathogens that are resistant to them, as well as due to side effects from the use of dysbacterioses, allergic reactions, etc.

Known methods of treating dyspepsia of a newborn youngster, including, as astringents and weakly disinfectants, such drugs of natural and plant origin as medicinal lignin, decoction of oak bark, infusion of sage leaves, St. John's wort, horse sorrel fruits [1].

These and other medicinal infusions and decoctions can not be used as the main means for the treatment of dyspepsia in newborn calves due to low efficiency, but only as concomitant drugs.

A known method of treating dyspepsia of newborn calves with milk extract of ripened walnuts on kerosene, which is administered by mouth after milk is milked 2 times a day for 4-5 days at a dose of 5-6 ml per head [2].

The disadvantages of the method are low efficiency in the case of complications of diseases of the gastrointestinal tract with pathogenic microflora, complexity of use, use as an extractant of aviation kerosene, not included in the register of medicines of Russia.

The technical result is an increase in the effectiveness of treatment, a decrease in its duration in cases of complications of conditionally pathogenic microflora, the use of a more technologically advanced method of drug administration.

This is achieved by the fact that alcohol-honey extract of walnuts of milk-wax ripeness with the addition of pollen and glycine is used as a therapeutic agent. The method of obtaining the extract is protected by patent RU 2223112.

Alcohol-honey extract of walnuts with milk-wax ripeness with the addition of pollen and glycine increases the resistance of the sick animals, has a strong restorative effect and at the same time has a wide range of antiviral, antibacterial and antimycotic effects.

The study established the therapeutic activity of the Extract against viral antigens isolated from calves with diarrheal syndrome, such as corona, rota, entero, parovirus, against most types of bacteria that can independently cause diarrhea in calves or complicate viral infections (Escherichia, salmonella, clostridia, etc.), as well as against chlamydia, cryptosporidia, eimeria and many pathogenic fungi.

Mode of application. Alcohol-honey extract of walnuts with milk-wax ripeness with the addition of pollen and glycine is administered to a sick animal in a portioned dose of liquid (colostrum, milk, water) at a rate of 0.5 ml per kilogram of live weight 2 times a day for 6 days.

In severe cases, the proposed extract is used along with specific therapy. Moreover, the use of the extract as the strongest natural adaptogen enhances the therapeutic activity of the drugs used, significantly reducing their side effects.

Example.

To study the therapeutic activity of the extract with diarrhea syndrome, 3 groups of 2-day-old calves with signs of diarrhea of 12 animals each were formed on the basis of analogues.

The calves of the 1st experimental group were treated with alcohol-honey extract of walnuts of milk-wax ripeness with the addition of pollen and glycine, the 2nd experimental group was treated with extract of walnuts of milk ripeness on kerosene, the control group of calves was treated with sulfopyridazine (1 time per day inside the first 2 days, 1.4 g each, and then 1 g each). The treatment was carried out until persistent signs of recovery appeared, while the duration of the disease and the safety of the calves in all groups were taken into account. To determine lysozyme activity in animals of all groups, blood was taken before and after 5 and 10 days after treatment.

The results of the study are presented in the table.

Table
The level of lysozyme in the blood serum of calves after giving drugs Calf group Lysozyme activity (units / ml) before treatment 5 days after treatment 10 days after treatment 1 experienced 28.5 30.5 33.8 2 experienced 28,4 29.8 32,4 Control 28.5 28.9 30.1

A persistent improvement in the clinical condition of animals of the 1st experimental group was observed 4-5 days after the start of treatment: appetite appeared, feces acquired a molded appearance, the skin became elastic, and the coat was shiny. In animals of the 2nd experimental group, such an improvement was observed 6-7 days after the start of treatment. Animals of the control group reached such a clinical condition only on the 10-11th day of treatment. In addition, in the control group of animals, 3 calves fell (25%), while in the experimental groups all the animals recovered (in the 1st experimental group by the 8-9th day of treatment, in the 2nd experimental group - by the 11-12th day of treatment )

The therapeutic effectiveness of the preparation of alcohol-honey extract of walnuts milk-wax ripeness with the addition of pollen and glycine was tested in the farms of the Volgograd region:

- Kuzmichevsky breeding farm, 95 calves were treated;

- Luch breeding farm, 44 calves were treated;

- Novonadezhdinsky breeding plant, 78 calves were treated.

When using the drug, deaths of calves were not fixed.

Information sources

1. Internal non-communicable diseases of farm animals. M .: Agropromizdat, 1991, p. 484.

2. RU No. 2179450.

Claims (1)

A method for the treatment of dyspepsia of young farm animals by oral administration of a medicinal product of natural origin, characterized in that as a medicinal product use alcohol-honey extract of walnuts milky-ripeness with the addition of pollen and glycine, which is administered with a dose of liquid 2 times per day for 6 days at a dose of 0.5 ml per 1 kg of animal weight.