RU2167877C2 - Производные конденсированных полициклических гетероциклических соединений и способ их получения - Google Patents

Производные конденсированных полициклических гетероциклических соединений и способ их получения Download PDF

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Publication number: RU2167877C2
Authority: RU; Russia
Prior art keywords: ring; group; optionally substituted; compound; oxo
Prior art date: 1995-05-31

Application number

RU97121851/04A

Other languages

English (en)

Russian (ru)

Other versions

RU97121851A (ru

Inventor

Сугуми Хироюки

Ниидзима Дзун

Котаке Йосихико

Окада Тосими

Камата Дзун-ити

Йосиматсу Кентаро

Нагасу Такеси

Накамура Кацудзи

Уенака Тосимицу

Ямагути Ацуми

Йосино Хироси

Коянаги Нозому

Кито Киосуке

Original Assignee

Эйсай Ко., Лтд.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-31

Filing date

1996-05-31

Publication date

2001-05-27

1996-05-31 Application filed by Эйсай Ко., Лтд. filed Critical Эйсай Ко., Лтд.

1999-10-27 Publication of RU97121851A publication Critical patent/RU97121851A/ru

2001-05-27 Application granted granted Critical

2001-05-27 Publication of RU2167877C2 publication Critical patent/RU2167877C2/ru

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

RU97121851/04A 1995-05-31 1996-05-31 Производные конденсированных полициклических гетероциклических соединений и способ их получения RU2167877C2 (ru)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP7/133992		1995-05-31
JP13399295		1995-05-31
JP7/309195		1995-11-28

Publications (2)

Publication Number	Publication Date
RU97121851A RU97121851A (ru)	1999-10-27
RU2167877C2 true RU2167877C2 (ru)	2001-05-27

Family

ID=15117861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RU97121851/04A RU2167877C2 (ru)	1995-05-31	1996-05-31	Производные конденсированных полициклических гетероциклических соединений и способ их получения

Country Status (3)

Country	Link
CA (1)	CA2220509C (ja)
RU (1)	RU2167877C2 (ja)
WO (1)	WO1996038446A1 (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2266906C1 (ru) *	2004-04-29	2005-12-27	Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия")	Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека
RU2389730C2 (ru) *	2005-01-10	2010-05-20	Тиботек Фармасьютикалз Лтд.	1,5,6-замещенные 2-оксо-3-циано-1,6а-диазатетрагидрофлуорантены
RU2393162C2 (ru) *	2008-09-12	2010-06-27	Государственное образовательное учреждение высшего профессионального образования САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ ХИМИКО-ФАРМАЦЕВТИЧЕСКАЯ АКАДЕМИЯ (ГОУ ВПО СПХФА Росздрава)	ЗАМЕЩЕННЫЕ 2Н,8Н-1,4-ДИОКСА-9b-АЗАФЕНАЛЕН-2,8-ДИОНЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ
RU2507204C2 (ru) *	2009-08-31	2014-02-20	Мерк Шарп И Доум Корп.	Положительные аллостерические модуляторы м1-рецепторов на основе пираниларилметилбензохиназолинона
RU2520966C2 (ru) *	2009-02-25	2014-06-27	Дайити Санкио Компани, Лимитед	Производное трициклического пиразолопиримидина
RU2527451C2 (ru) *	2008-12-11	2014-08-27	Вайв Хелткер Компани	Синтез карбамоилпиридоновых ингибиторов интегразы вич и промежуточных соединений
US9260418B2 (en)	2009-08-31	2016-02-16	Merck Sharp & Dohme Corp.	Pyranyl aryl methyl benzoquinolinone M1 receptor positive allosteric modulators
RU2591194C2 (ru) *	2010-04-22	2016-07-10	Интра-Селлулар Терапиз, Инк.	Органические соединения

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101541811B (zh) *	2006-09-19	2014-07-09	第一三共株式会社	吡唑并嘧啶衍生物

Citations (3)

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Publication number	Priority date	Publication date	Assignee	Title
GB912289A (en) *	1959-06-09	1962-12-05	Geigy Ag J R	New basic ethers and processes for their production
US3962438A (en) *	1975-01-07	1976-06-08	Smithkline Corporation	Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones
WO1992000281A1 (en) *	1990-06-26	1992-01-09	Research Corporation Technologies, Inc.	1,2-dihydro-3h-dibenzisoquinoline-1,3-dione anticancer agents

1996
- 1996-05-31 CA CA002220509A patent/CA2220509C/en not_active Expired - Fee Related
- 1996-05-31 RU RU97121851/04A patent/RU2167877C2/ru not_active IP Right Cessation
- 1996-05-31 WO PCT/JP1996/001487 patent/WO1996038446A1/ja not_active Ceased

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB912289A (en) *	1959-06-09	1962-12-05	Geigy Ag J R	New basic ethers and processes for their production
US3962438A (en) *	1975-01-07	1976-06-08	Smithkline Corporation	Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones
WO1992000281A1 (en) *	1990-06-26	1992-01-09	Research Corporation Technologies, Inc.	1,2-dihydro-3h-dibenzisoquinoline-1,3-dione anticancer agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANTONINI IPPOLITO ET ALL. "Synthesis of (dialkylamino)alkyl disubsubstituted pyrimido[5,6,1-de]acridines" J.Med.Chem, 1995, v.38. № 17, р.3282-3286. *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2266906C1 (ru) *	2004-04-29	2005-12-27	Общество с ограниченной ответственностью "Исследовательский Институт Химического Разнообразия" (ООО "Исследовательский Институт Химического Разнообразия")	Анелированные карбамоилазагетероциклы, способы их получения (варианты), фармацевтическая композиция, фокусированная библиотека
RU2389730C2 (ru) *	2005-01-10	2010-05-20	Тиботек Фармасьютикалз Лтд.	1,5,6-замещенные 2-оксо-3-циано-1,6а-диазатетрагидрофлуорантены
RU2393162C2 (ru) *	2008-09-12	2010-06-27	Государственное образовательное учреждение высшего профессионального образования САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ ХИМИКО-ФАРМАЦЕВТИЧЕСКАЯ АКАДЕМИЯ (ГОУ ВПО СПХФА Росздрава)	ЗАМЕЩЕННЫЕ 2Н,8Н-1,4-ДИОКСА-9b-АЗАФЕНАЛЕН-2,8-ДИОНЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ
RU2527451C2 (ru) *	2008-12-11	2014-08-27	Вайв Хелткер Компани	Синтез карбамоилпиридоновых ингибиторов интегразы вич и промежуточных соединений
RU2520966C2 (ru) *	2009-02-25	2014-06-27	Дайити Санкио Компани, Лимитед	Производное трициклического пиразолопиримидина
RU2507204C2 (ru) *	2009-08-31	2014-02-20	Мерк Шарп И Доум Корп.	Положительные аллостерические модуляторы м1-рецепторов на основе пираниларилметилбензохиназолинона
US8846702B2 (en)	2009-08-31	2014-09-30	Merck Sharp & Dohme Corp.	Pyranyl aryl methyl benzoquinazolinone M1 receptor positive allosteric modulators
US9260418B2 (en)	2009-08-31	2016-02-16	Merck Sharp & Dohme Corp.	Pyranyl aryl methyl benzoquinolinone M1 receptor positive allosteric modulators
RU2591194C2 (ru) *	2010-04-22	2016-07-10	Интра-Селлулар Терапиз, Инк.	Органические соединения

Also Published As

Publication number	Publication date
CA2220509A1 (en)	1996-12-05
WO1996038446A1 (en)	1996-12-05
CA2220509C (en)	2005-07-05

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Legal Events

Date	Code	Title	Description
2010-09-10	PC4A	Invention patent assignment	Effective date: 20100727
2013-03-27	MM4A	The patent is invalid due to non-payment of fees	Effective date: 20120601