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RU2018132749A3 - - Google Patents

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Publication number
RU2018132749A3
RU2018132749A3 RU2018132749A RU2018132749A RU2018132749A3 RU 2018132749 A3 RU2018132749 A3 RU 2018132749A3 RU 2018132749 A RU2018132749 A RU 2018132749A RU 2018132749 A RU2018132749 A RU 2018132749A RU 2018132749 A3 RU2018132749 A3 RU 2018132749A3
Authority
RU
Russia
Application number
RU2018132749A
Other versions
RU2018132749A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2018132749A publication Critical patent/RU2018132749A/ru
Publication of RU2018132749A3 publication Critical patent/RU2018132749A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
RU2018132749A 2016-02-26 2017-02-24 Новый токсин и способ получения его промежуточного соединения RU2018132749A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201610107901 2016-02-26
CN201610107901.X 2016-02-26
PCT/CN2017/074756 WO2017144015A1 (zh) 2016-02-26 2017-02-24 一种新毒素及其中间体的制备方法

Publications (2)

Publication Number Publication Date
RU2018132749A RU2018132749A (ru) 2020-03-26
RU2018132749A3 true RU2018132749A3 (ru) 2020-04-14

Family

ID=59685835

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018132749A RU2018132749A (ru) 2016-02-26 2017-02-24 Новый токсин и способ получения его промежуточного соединения

Country Status (13)

Country Link
US (1) US10513510B2 (ru)
EP (1) EP3421463A4 (ru)
JP (1) JP2019510000A (ru)
KR (1) KR20180115743A (ru)
CN (1) CN107531680B (ru)
AU (1) AU2017223532A1 (ru)
BR (1) BR112018016983A2 (ru)
CA (1) CA3015098A1 (ru)
HK (1) HK1244805A1 (ru)
MX (1) MX2018010128A (ru)
RU (1) RU2018132749A (ru)
TW (1) TWI732826B (ru)
WO (1) WO2017144015A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109963835B (zh) * 2017-09-04 2022-10-21 江苏恒瑞医药股份有限公司 一种新毒素及其中间体的制备方法
CN112390853A (zh) * 2019-08-11 2021-02-23 复旦大学 海兔毒素10类似物及其制备方法
AU2021317378A1 (en) 2020-07-27 2023-03-09 Tuojie Biotech (Shanghai) Co., Ltd. Anti-CD79B antibody-drug conjugate, and preparation method therefor and pharmaceutical use thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861170B1 (fr) 2003-10-16 2006-01-20 Tijani Gharbi Dispositif optique pour determiner au moins une caracteristique dimensionnelle d'une goutte de liquide
PL1725249T3 (pl) * 2003-11-06 2014-06-30 Seattle Genetics Inc Związki monometylowaliny zdolne do sprzęgania do ligandów
EP3088004B1 (en) * 2004-09-23 2018-03-28 Genentech, Inc. Cysteine engineered antibodies and conjugates
AR064561A1 (es) 2006-12-28 2009-04-08 Actelion Pharmaceuticals Ltd Derivados de 2-aza-biciclo[3.1.0]hexano y su uso en la preparacion de un medicamento para el tratamiento de enfermedades relacionadas con disfunciones generales del sistema de la orexina.
TWI476190B (zh) * 2009-03-30 2015-03-11 必治妥美雅史谷比公司 C型肝炎病毒抑制劑
CN106117312A (zh) 2011-04-21 2016-11-16 西雅图基因公司 新的结合剂‑药物缀合物(adc)及其用途
JP6192233B2 (ja) 2011-11-17 2017-09-06 ファイザー・インク 細胞毒性ペプチドおよびその抗体薬物コンジュゲート
SG11201403085PA (en) 2011-12-14 2014-10-30 Seattle Genetics Inc Fgfr antibody drug conjugates (adcs) and the use thereof
FR3005051A1 (fr) * 2013-04-25 2014-10-31 Pf Medicament Derives de la dolastatine 10 et d'auristatines
US10314921B2 (en) * 2014-04-25 2019-06-11 Pierre Fabre Medicament Antibody-drug-conjugate and its use for the treatment of cancer
CN106794258B (zh) 2015-02-15 2019-07-12 江苏恒瑞医药股份有限公司 配体-细胞毒性药物偶联物、其制备方法及其应用
CN106188293A (zh) * 2015-04-17 2016-12-07 江苏恒瑞医药股份有限公司 抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途

Also Published As

Publication number Publication date
CN107531680A (zh) 2018-01-02
AU2017223532A1 (en) 2018-08-30
TW201730185A (zh) 2017-09-01
TWI732826B (zh) 2021-07-11
MX2018010128A (es) 2019-01-21
US10513510B2 (en) 2019-12-24
JP2019510000A (ja) 2019-04-11
EP3421463A4 (en) 2019-10-23
CN107531680B (zh) 2020-09-11
RU2018132749A (ru) 2020-03-26
HK1244805A1 (zh) 2018-08-17
WO2017144015A1 (zh) 2017-08-31
US20190055223A1 (en) 2019-02-21
CA3015098A1 (en) 2017-08-31
BR112018016983A2 (pt) 2018-12-26
KR20180115743A (ko) 2018-10-23
EP3421463A1 (en) 2019-01-02

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Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20200909