RU2008138124A - METHOD FOR PREVENTION AND TREATMENT OF DISEASES CAUSED BY HUMAN SUBSTYPE H5N1 VIRUS INFLUENZA VIRUS USING INTERFERON INDUCTOR AND NEURAMINIDASE INHIBITOR - Google Patents
METHOD FOR PREVENTION AND TREATMENT OF DISEASES CAUSED BY HUMAN SUBSTYPE H5N1 VIRUS INFLUENZA VIRUS USING INTERFERON INDUCTOR AND NEURAMINIDASE INHIBITOR Download PDFInfo
- Publication number
- RU2008138124A RU2008138124A RU2008138124/13A RU2008138124A RU2008138124A RU 2008138124 A RU2008138124 A RU 2008138124A RU 2008138124/13 A RU2008138124/13 A RU 2008138124/13A RU 2008138124 A RU2008138124 A RU 2008138124A RU 2008138124 A RU2008138124 A RU 2008138124A
- Authority
- RU
- Russia
- Prior art keywords
- neuraminidase inhibitor
- prevention
- influenza virus
- treatment
- ridostin
- Prior art date
Links
- 229940123424 Neuraminidase inhibitor Drugs 0.000 title claims abstract 7
- 239000002911 sialidase inhibitor Substances 0.000 title claims abstract 7
- 238000011282 treatment Methods 0.000 title claims abstract 5
- 241000712461 unidentified influenza virus Species 0.000 title claims abstract 5
- 241001473385 H5N1 subtype Species 0.000 title claims abstract 3
- 201000010099 disease Diseases 0.000 title claims abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract 3
- 238000000034 method Methods 0.000 title claims abstract 3
- 230000002265 prevention Effects 0.000 title claims abstract 3
- 241000282414 Homo sapiens Species 0.000 title 1
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 239000002799 interferon inducing agent Substances 0.000 claims abstract 8
- 208000015181 infectious disease Diseases 0.000 claims abstract 6
- VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 claims abstract 4
- 229960003752 oseltamivir Drugs 0.000 claims abstract 4
- 206010064097 avian influenza Diseases 0.000 claims abstract 2
- 230000006806 disease prevention Effects 0.000 claims abstract 2
- 239000007924 injection Substances 0.000 claims abstract 2
- 238000002347 injection Methods 0.000 claims abstract 2
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Способ профилактики и лечения заболеваний, вызванных штаммами субтипа H5N1 вируса гриппа птиц, с использованием индуктора интерферона и ингибитора нейраминидазы, включающий введение в организм препарата индуктора интерферона или совместно индуктора интерферона и ингибитора нейраминидазы озельтамивира, отличающийся тем, что в качестве индуктора интеферона используют препарат Ридостин, который вводят в организм в виде инъекций при профилактике заболеваний в диапазоне доз от 0,05 до 0,5 мг/кг 1 раз в сутки и далее через 1 и 3 суток после первого введения Ридостина, а при лечении в организм вводят Ридостин в виде инъекций в диапазоне доз от 0,05 до 0,5 мг/кг 1 раз в сутки в день инфицирования и далее через 1 и 3 суток после инфицирования и ингибитор нейраминидазы озельтамивир перорально в диапазоне доз от 0,2 до 2 мг/кг 2 раза в сутки в течение 5-7 суток после инфицирования вирусом гриппа H5N1.A method for the prevention and treatment of diseases caused by strains of the H5N1 subtype of avian influenza virus using an interferon inducer and a neuraminidase inhibitor, comprising administering an interferon inducer preparation or an interferon inducer and an oseltamivir neuraminidase inhibitor, characterized in that Ridostin is used as an interferon inducer, which is injected into the body in the prevention of diseases in the dose range from 0.05 to 0.5 mg / kg 1 time per day and then 1 and 3 days after the first administration of Ridostin, and during treatment, Ridostin is administered into the body in the form of injections in the dose range from 0.05 to 0.5 mg / kg once a day per day of infection and then 1 and 3 days after infection and the neuraminidase inhibitor oseltamivir orally in the range doses from 0.2 to 2 mg / kg 2 times a day for 5-7 days after infection with the H5N1 influenza virus.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008138124/13A RU2398596C2 (en) | 2008-09-24 | 2008-09-24 | Methods of prevention and treatment of diseases caused by a/h5n1 bird influenza virus with using interferon inducer and neuraminidase inhibitor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2008138124/13A RU2398596C2 (en) | 2008-09-24 | 2008-09-24 | Methods of prevention and treatment of diseases caused by a/h5n1 bird influenza virus with using interferon inducer and neuraminidase inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008138124A true RU2008138124A (en) | 2010-03-27 |
| RU2398596C2 RU2398596C2 (en) | 2010-09-10 |
Family
ID=42138116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008138124/13A RU2398596C2 (en) | 2008-09-24 | 2008-09-24 | Methods of prevention and treatment of diseases caused by a/h5n1 bird influenza virus with using interferon inducer and neuraminidase inhibitor |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2398596C2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8420617B2 (en) * | 2011-03-11 | 2013-04-16 | Biocell Laboratories | Multiantivirus compound, composition and method for treatment of virus diseases |
| RU2502512C2 (en) * | 2012-01-18 | 2013-12-27 | Общество с ограниченной ответственностью "ВИТАЛАНГ" | Method of treating avian influenza |
| RU2721876C1 (en) * | 2019-10-31 | 2020-05-25 | Юрий Михайлович Амбалов | Method for etiopathogenetic treatment of influenza patients |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2083221C1 (en) * | 1993-01-12 | 1997-07-10 | Научно-исследовательский конструкторско-технологический институт биологически активных веществ Научно-производственного объединения "Вектор" | Ridostin as interferon inductor |
| US20060035859A1 (en) * | 2003-05-16 | 2006-02-16 | Hemispherx Biopharma | Treating severe and acute viral infections |
-
2008
- 2008-09-24 RU RU2008138124/13A patent/RU2398596C2/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2398596C2 (en) | 2010-09-10 |
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| Date | Code | Title | Description |
|---|---|---|---|
| PD4A | Correction of name of patent owner | ||
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20140925 |