RU2063761C1 - Method for obtaining antiinflammatory and immunostimulating substance from placenta - Google Patents
Method for obtaining antiinflammatory and immunostimulating substance from placenta Download PDFInfo
- Publication number
- RU2063761C1 RU2063761C1 SU5013746A RU2063761C1 RU 2063761 C1 RU2063761 C1 RU 2063761C1 SU 5013746 A SU5013746 A SU 5013746A RU 2063761 C1 RU2063761 C1 RU 2063761C1
- Authority
- RU
- Russia
- Prior art keywords
- placenta
- obtaining
- antiinflammatory
- immunostimulating substance
- substance
- Prior art date
Links
- 210000002826 placenta Anatomy 0.000 title claims abstract description 8
- 238000000034 method Methods 0.000 title claims abstract description 6
- 239000000126 substance Substances 0.000 title claims abstract description 4
- 230000003110 anti-inflammatory effect Effects 0.000 title claims 2
- 230000003308 immunostimulating effect Effects 0.000 title claims 2
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 3
- 210000001691 amnion Anatomy 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 4
- 238000002360 preparation method Methods 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 abstract description 2
- 239000012528 membrane Substances 0.000 abstract 2
- 239000013049 sediment Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
FIELD: medicine. SUBSTANCE: method involves comminuting placenta matter and adding water. According to the invention, placenta is used with aminotic membrane, liquid above sediment is treated by applying ultrafiltration method. Aminotic membrane is to be frozen together with placenta and then defrosted. EFFECT: enhanced effectiveness of the preparation.
Description
Изобретение относится к медицине, а именно к способу получения лекарственных средств из биологических веществ. The invention relates to medicine, namely to a method for producing medicines from biological substances.
Наиболее близким к заявляемому способу является способ получения лекарственного средства "Терапевтический агент", патент США N 4054648, А 61 К 35/50, 1977г. Closest to the claimed method is a method of obtaining a medicinal product "Therapeutic agent", US patent N 4054648, A 61 K 35/50, 1977
Способ осуществляют следующим образом. The method is as follows.
Плаценту измельчают, добавляют жидкость, согласно изобретению, используют плаценту с амниотической оболочкой, надосадочную жидкость подвергают ультрафильтрации. Поставленная цель достигается также тем, что взятую амниотическую оболочку вместе с плацентой замораживают, затем размораживают. Полученный препарат хранят в морозильной камере, а перед применением размораживают и согревают до 36oС. Возможна лиофилизация препарата, лиофилизат хранят в темном прохладном месте.The placenta is crushed, the liquid according to the invention is added, the placenta with an amniotic membrane is used, the supernatant is subjected to ultrafiltration. This goal is also achieved by the fact that the taken amniotic membrane along with the placenta is frozen, then thawed. The resulting preparation is stored in a freezer, and before use it is thawed and warmed to 36 o C. Lyophilization of the preparation is possible, the lyophilisate is stored in a dark, cool place.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU5013746 RU2063761C1 (en) | 1991-11-22 | 1991-11-22 | Method for obtaining antiinflammatory and immunostimulating substance from placenta |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU5013746 RU2063761C1 (en) | 1991-11-22 | 1991-11-22 | Method for obtaining antiinflammatory and immunostimulating substance from placenta |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2063761C1 true RU2063761C1 (en) | 1996-07-20 |
Family
ID=21590133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU5013746 RU2063761C1 (en) | 1991-11-22 | 1991-11-22 | Method for obtaining antiinflammatory and immunostimulating substance from placenta |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2063761C1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2128514C1 (en) * | 1997-11-13 | 1999-04-10 | Общество с ограниченной ответственностью "НИР" | Method of anti-inflammatory agent preparing |
| RU2167664C2 (en) * | 1998-12-28 | 2001-05-27 | Научный центр клинической и экспериментальной медицины СО РАМН | Anti-inflammatory and immunomodulating agent |
| RU2246308C2 (en) * | 2003-04-25 | 2005-02-20 | ЗАО "Научно-производственное объединение "ЭКРОС" | Bioconcentrate from placenta |
| EP1549328A4 (en) * | 2002-09-18 | 2009-07-08 | Emiliano Ghinelli | Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin |
-
1991
- 1991-11-22 RU SU5013746 patent/RU2063761C1/en active
Non-Patent Citations (1)
| Title |
|---|
| Патент США N 4054648, A 61 K 35/50, 1977. * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2128514C1 (en) * | 1997-11-13 | 1999-04-10 | Общество с ограниченной ответственностью "НИР" | Method of anti-inflammatory agent preparing |
| RU2167664C2 (en) * | 1998-12-28 | 2001-05-27 | Научный центр клинической и экспериментальной медицины СО РАМН | Anti-inflammatory and immunomodulating agent |
| EP1549328A4 (en) * | 2002-09-18 | 2009-07-08 | Emiliano Ghinelli | Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin |
| US7871646B2 (en) | 2002-09-18 | 2011-01-18 | Repsco Llp | Use of a human amniotic membrane composition for prophylaxis and treatment of diseases and conditions of the eye and skin |
| RU2246308C2 (en) * | 2003-04-25 | 2005-02-20 | ЗАО "Научно-производственное объединение "ЭКРОС" | Bioconcentrate from placenta |
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