RO81048B - Procedeu pentru prepararea unor derivati de piramona - Google Patents
Procedeu pentru prepararea unor derivati de piramonaInfo
- Publication number
- RO81048B RO81048B RO100749A RO10074980A RO81048B RO 81048 B RO81048 B RO 81048B RO 100749 A RO100749 A RO 100749A RO 10074980 A RO10074980 A RO 10074980A RO 81048 B RO81048 B RO 81048B
- Authority
- RO
- Romania
- Prior art keywords
- derivatives
- general formula
- pyramone
- preparing
- formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical class CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 1
- XTHFKEDIFFGKHM-UHFFFAOYSA-N Dimethoxyethane Chemical compound COCCOC XTHFKEDIFFGKHM-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- XOCUXOWLYLLJLV-UHFFFAOYSA-N [O].[S] Chemical group [O].[S] XOCUXOWLYLLJLV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal alkoxide Chemical class 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Abstract
Procedeu pentru prepararea unor derivati de piramona cu formula generala I: (vezi formula) în care R1 este o grupare R2-(Z)m- în care m este 0 sau 1, Z reprezinta un atom de oxigen de sulf, gruparea SO sau CO si R2 reprezinta radicalul fenil, eventual substituit cu halogen alchil interior, R3 reprezinta un radical alchil inferior, si anume un derivat de butanona cu formula generala II: (vezi formula) în care R1 are semnificatiile sus mentionate se supune reactiei cu un dialchiloxalat cu formula generala III: (vezi formula) în care R3 are semnificatiile sus mentionate în mediu de alcanol inferior, eter sau dimetoxietan si în prezenta unui alcoxid de metal alcalin, urmata de tratarea cu o solutie de acid mineral si eventual convertirea compusului obtinut în aer liber, amide, nitrili sau alti eteri, prin metode cunoscute.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7912063 | 1979-04-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO81048B true RO81048B (ro) | 1983-01-30 |
| RO81048A RO81048A (ro) | 1983-02-01 |
Family
ID=10504372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO80100749A RO81048A (ro) | 1979-04-05 | 1980-04-05 | Procedeu pentru prepararea unor derivati de piramona |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4364956A (ro) |
| JP (1) | JPS55133376A (ro) |
| AR (1) | AR225918A1 (ro) |
| AT (1) | AT368499B (ro) |
| AU (1) | AU535315B2 (ro) |
| BE (1) | BE882644A (ro) |
| CA (1) | CA1142944A (ro) |
| CH (1) | CH646967A5 (ro) |
| CS (1) | CS214826B2 (ro) |
| DD (1) | DD150002A5 (ro) |
| DE (1) | DE3012597A1 (ro) |
| DK (1) | DK142180A (ro) |
| ES (1) | ES490122A0 (ro) |
| FI (1) | FI801020A7 (ro) |
| FR (1) | FR2453168A1 (ro) |
| GB (2) | GB2123814B (ro) |
| GR (1) | GR67760B (ro) |
| HU (1) | HU184257B (ro) |
| IE (1) | IE49581B1 (ro) |
| IL (1) | IL59748A (ro) |
| IT (1) | IT1143086B (ro) |
| LU (1) | LU82334A1 (ro) |
| NL (1) | NL8002025A (ro) |
| NZ (1) | NZ193343A (ro) |
| PH (1) | PH14895A (ro) |
| PL (1) | PL123700B1 (ro) |
| PT (1) | PT71050A (ro) |
| RO (1) | RO81048A (ro) |
| SE (1) | SE8002515L (ro) |
| SU (1) | SU976850A3 (ro) |
| YU (1) | YU92080A (ro) |
| ZA (1) | ZA801977B (ro) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4603144A (en) * | 1984-08-16 | 1986-07-29 | G. D. Searle & Co. | Kojic acid ether-ester derivatives |
| DE3600287A1 (de) * | 1986-01-08 | 1987-07-16 | Bayer Ag | 1-arylpyrazole |
| JPH0778059B2 (ja) * | 1986-03-11 | 1995-08-23 | ダイセル化学工業株式会社 | ピロン−３−カルボキサミド誘導体及び除草剤 |
| DE3831695A1 (de) * | 1988-09-17 | 1990-03-22 | Hoechst Ag | Elaiophylinderivate, verfahren zu ihrer herstellung ihre verwendung als arzneimittel und sie enthaltende arzneimittel |
| GB8920519D0 (en) * | 1989-09-11 | 1989-10-25 | Rhone Poulenc Ltd | New compositions of matter |
| US5747424A (en) * | 1989-09-11 | 1998-05-05 | Rhone-Poulenc Agriculture Ltd. | Herbicidal 4-substituted isoxazol |
| US5656573A (en) * | 1989-09-11 | 1997-08-12 | Rhone-Poulenc Agriculture Ltd. | Herbicidal 4-substituted isoxazoles |
| US5650533A (en) * | 1989-09-11 | 1997-07-22 | Rhone-Poulenc Agriculture Ltd. | Intermediates to herbicidal 4-substituted isoxazoles |
| DE4031723A1 (de) * | 1990-10-06 | 1992-04-09 | Basf Ag | Verfahren zur herstellung von (alpha),(beta)-ungesaettigten carbonylverbindungen |
| TW587079B (en) | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
| AR029489A1 (es) * | 2000-03-10 | 2003-07-02 | Euro Celtique Sa | Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento |
| PE20011333A1 (es) | 2000-03-16 | 2002-01-16 | Almirall Prodesfarma Ag | Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2 |
| AR037233A1 (es) | 2001-09-07 | 2004-11-03 | Euro Celtique Sa | Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento |
| AR036873A1 (es) | 2001-09-07 | 2004-10-13 | Euro Celtique Sa | Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento |
| US20090053641A1 (en) * | 2005-03-24 | 2009-02-26 | Kazuyoshi Kuroda | Charge control agent and related art |
| WO2006101144A1 (ja) * | 2005-03-24 | 2006-09-28 | Orient Chemical Industries, Ltd. | 荷電制御剤及びその関連技術 |
| EP3204347B1 (en) | 2015-12-23 | 2024-10-23 | Commonwealth Scientific and Industrial Research Organisation | Enamine compounds for protecting against uv radiation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4065290A (en) * | 1975-07-03 | 1977-12-27 | Eli Lilly And Company | Herbicidal β-phenyl-4-piperidinones |
| US4060533A (en) * | 1976-06-25 | 1977-11-29 | Sandoz, Inc. | Pyranone carboxamides |
-
1980
- 1980-03-31 IL IL59748A patent/IL59748A/xx unknown
- 1980-03-31 ES ES490122A patent/ES490122A0/es active Granted
- 1980-04-01 PH PH23844A patent/PH14895A/en unknown
- 1980-04-01 DE DE19803012597 patent/DE3012597A1/de not_active Withdrawn
- 1980-04-01 AU AU57031/80A patent/AU535315B2/en not_active Expired - Fee Related
- 1980-04-01 FI FI801020A patent/FI801020A7/fi not_active Application Discontinuation
- 1980-04-01 DK DK142180A patent/DK142180A/da not_active IP Right Cessation
- 1980-04-01 SE SE8002515A patent/SE8002515L/xx not_active Application Discontinuation
- 1980-04-02 AT AT0181880A patent/AT368499B/de not_active IP Right Cessation
- 1980-04-02 HU HU80785A patent/HU184257B/hu unknown
- 1980-04-02 PT PT71050A patent/PT71050A/pt unknown
- 1980-04-02 CH CH258980A patent/CH646967A5/fr not_active IP Right Cessation
- 1980-04-02 ZA ZA00801977A patent/ZA801977B/xx unknown
- 1980-04-02 NZ NZ193343A patent/NZ193343A/xx unknown
- 1980-04-02 IE IE671/80A patent/IE49581B1/en unknown
- 1980-04-02 FR FR8007447A patent/FR2453168A1/fr active Granted
- 1980-04-02 GR GR61605A patent/GR67760B/el unknown
- 1980-04-03 PL PL1980223229A patent/PL123700B1/pl unknown
- 1980-04-03 CA CA000349145A patent/CA1142944A/en not_active Expired
- 1980-04-03 GB GB08312570A patent/GB2123814B/en not_active Expired
- 1980-04-03 YU YU00920/80A patent/YU92080A/xx unknown
- 1980-04-03 DD DD80220217A patent/DD150002A5/de unknown
- 1980-04-03 GB GB8011365A patent/GB2047697B/en not_active Expired
- 1980-04-03 BE BE6/47126A patent/BE882644A/fr not_active IP Right Cessation
- 1980-04-04 CS CS802358A patent/CS214826B2/cs unknown
- 1980-04-04 NL NL8002025A patent/NL8002025A/nl not_active Application Discontinuation
- 1980-04-04 LU LU82334A patent/LU82334A1/fr unknown
- 1980-04-04 IT IT48348/80A patent/IT1143086B/it active
- 1980-04-04 SU SU802905747A patent/SU976850A3/ru active
- 1980-04-04 JP JP4455080A patent/JPS55133376A/ja active Pending
- 1980-04-05 RO RO80100749A patent/RO81048A/ro unknown
- 1980-04-07 AR AR280568A patent/AR225918A1/es active
-
1981
- 1981-09-17 US US06/303,307 patent/US4364956A/en not_active Expired - Fee Related
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