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PT941066E - Complexos de lipido cationico - acido nucleico - Google Patents

Complexos de lipido cationico - acido nucleico

Info

Publication number
PT941066E
PT941066E PT97934685T PT97934685T PT941066E PT 941066 E PT941066 E PT 941066E PT 97934685 T PT97934685 T PT 97934685T PT 97934685 T PT97934685 T PT 97934685T PT 941066 E PT941066 E PT 941066E
Authority
PT
Portugal
Prior art keywords
nucleic acid
complexes
cationic lipid
lipid
suspension
Prior art date
Application number
PT97934685T
Other languages
English (en)
Inventor
Rainer Bischoff
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Publication of PT941066E publication Critical patent/PT941066E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT97934685T 1996-08-26 1997-08-25 Complexos de lipido cationico - acido nucleico PT941066E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96401819 1996-08-26
PCT/IB1997/001030 WO1998008489A1 (en) 1996-08-26 1997-08-25 Cationic lipid-nucleic acid complexes

Publications (1)

Publication Number Publication Date
PT941066E true PT941066E (pt) 2004-03-31

Family

ID=8225285

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97934685T PT941066E (pt) 1996-08-26 1997-08-25 Complexos de lipido cationico - acido nucleico

Country Status (11)

Country Link
US (1) US6271208B1 (pt)
EP (1) EP0941066B1 (pt)
JP (1) JP2000516948A (pt)
AT (1) ATE252891T1 (pt)
AU (1) AU729077B2 (pt)
CA (1) CA2264140A1 (pt)
DE (1) DE69725877T2 (pt)
DK (1) DK0941066T3 (pt)
ES (1) ES2208936T3 (pt)
PT (1) PT941066E (pt)
WO (1) WO1998008489A1 (pt)

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US20040180438A1 (en) * 2002-04-26 2004-09-16 Pachuk Catherine J. Methods and compositions for silencing genes without inducing toxicity
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JP5249016B2 (ja) 2006-03-28 2013-07-31 日本化薬株式会社 タキサン類の高分子結合体
CA2652656A1 (en) 2006-05-18 2007-11-29 Nippon Kayaku Kabushiki Kaisha High-molecular weight conjugate of podophyllotoxins
EP2080779B1 (en) 2006-11-06 2016-05-18 Nippon Kayaku Kabushiki Kaisha Polymeric derivative of nucleic acid metabolic antagonist
WO2008056654A1 (fr) 2006-11-08 2008-05-15 Nippon Kayaku Kabushiki Kaisha Dérivé polymère d'un antagoniste métabolique d'acide nucléique
US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
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JP5349318B2 (ja) 2007-09-28 2013-11-20 日本化薬株式会社 ステロイド類の高分子結合体
JP5687899B2 (ja) * 2008-03-18 2015-03-25 日本化薬株式会社 生理活性物質の高分子結合体
JP5366940B2 (ja) 2008-05-08 2013-12-11 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
RU2476204C2 (ru) * 2008-06-19 2013-02-27 Ниппон Синяку Ко., Лтд. Носитель лекарственного средства
JP5544357B2 (ja) 2009-05-15 2014-07-09 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
EP3403647A1 (en) 2009-12-01 2018-11-21 Translate Bio, Inc. Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
KR20140024833A (ko) 2010-11-17 2014-03-03 니폰 가야꾸 가부시끼가이샤 신규한 시티딘계 대사길항제의 고분자 유도체
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JP6620093B2 (ja) * 2013-07-23 2019-12-11 アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ メッセンジャーｒｎａを送達するための組成物及び方法
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MX373952B (es) 2014-04-25 2020-07-13 Shire Human Genetic Therapies Métodos de purificación de arn mensajero.
MX2019010155A (es) 2017-02-27 2020-12-10 Translate Bio Inc Arnm de cftr optimizado por codón novedoso.
MA49138A (fr) 2017-05-16 2020-03-25 Translate Bio Inc Traitement de la fibrose kystique par administration d'arnm à codons optimisés codant pour la cftr
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US5705385A (en) * 1995-06-07 1998-01-06 Inex Pharmaceuticals Corporation Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer

Also Published As

Publication number Publication date
DK0941066T3 (da) 2004-02-23
AU729077B2 (en) 2001-01-25
JP2000516948A (ja) 2000-12-19
CA2264140A1 (en) 1998-03-05
DE69725877T2 (de) 2004-07-22
WO1998008489A1 (en) 1998-03-05
EP0941066A1 (en) 1999-09-15
ES2208936T3 (es) 2004-06-16
ATE252891T1 (de) 2003-11-15
AU3781597A (en) 1998-03-19
US6271208B1 (en) 2001-08-07
DE69725877D1 (de) 2003-12-04
EP0941066B1 (en) 2003-10-29

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