PT89956A - Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados - Google Patents
Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivadosInfo
- Publication number
- PT89956A PT89956A PT89956A PT8995689A PT89956A PT 89956 A PT89956 A PT 89956A PT 89956 A PT89956 A PT 89956A PT 8995689 A PT8995689 A PT 8995689A PT 89956 A PT89956 A PT 89956A
- Authority
- PT
- Portugal
- Prior art keywords
- quinolonocarboxylic
- cyclopropyl
- derivatives
- acids
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3808118A DE3808118A1 (de) | 1988-03-11 | 1988-03-11 | Verfahren zur herstellung von 1-cyclopropyl-chinoloncarbonsaeuren und deren derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT89956A true PT89956A (pt) | 1989-11-10 |
Family
ID=6349471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89956A PT89956A (pt) | 1988-03-11 | 1989-03-09 | Processo para a preparacao de acidos 1-ciclopropil-quinolonocarboxilicos e seus derivados |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0332930A2 (pt) |
| JP (1) | JPH01268679A (pt) |
| KR (1) | KR890014489A (pt) |
| CN (1) | CN1037335A (pt) |
| DE (1) | DE3808118A1 (pt) |
| FI (1) | FI891123L (pt) |
| IL (1) | IL89535A0 (pt) |
| PT (1) | PT89956A (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT67395A (en) * | 1993-07-13 | 1995-04-28 | Somfai | Method for the n-cyclopropylation of primary and secondary aromatic amines |
| EP1042295B1 (en) * | 1997-12-22 | 2005-09-07 | Pharmacia & Upjohn Company LLC | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents |
| PL2489659T3 (pl) | 2004-06-24 | 2018-06-29 | Vertex Pharma | Modulatory transporterów posiadających kasetę wiążącą atp |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| CN1305849C (zh) * | 2004-12-29 | 2007-03-21 | 江苏正大天晴药业股份有限公司 | 3－甲氨基哌啶及其盐的制备方法 |
| CN100457737C (zh) * | 2005-04-05 | 2009-02-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 喹啉酰胺衍生物、其制备方法和用途 |
| JP5409010B2 (ja) | 2005-12-28 | 2014-02-05 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ｎ−［２，４−ビス（１，１−ジメチルエチル）−５−ヒドロキシフェニル］−１，４−ジヒドロ−４−オキソキノリン−３−カルボキサミドの固体形態 |
| EP2383271B1 (en) | 2006-03-13 | 2013-07-10 | Kyorin Pharmaceutical Co., Ltd. | Aminoquinolones as GSK-3 Inhibitors |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| JP5502889B2 (ja) | 2009-03-11 | 2014-05-28 | 杏林製薬株式会社 | ｇｓｋ−３阻害剤としての７−シクロアルキルアミノキノロン |
| US8476442B2 (en) | 2009-03-20 | 2013-07-02 | Vertex Pharmaceutical Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| CA2865519C (en) | 2012-02-27 | 2018-01-02 | Vertex Pharmaceuticals Incorporated | Pharmaceutical compositions comprising a solid dispersion of n-[2,4-bis(1,1-dimethylethyl0-5-hydroxyphenyl-1]-1,4-dihydro-4-oxoquinolone-3-carboxamide for treating cystic fibrosis |
| KR20170063954A (ko) | 2014-10-07 | 2017-06-08 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정 |
| CN107602465A (zh) * | 2016-07-12 | 2018-01-19 | 重庆大学 | 一种喹诺酮类衍生物及其应用 |
-
1988
- 1988-03-11 DE DE3808118A patent/DE3808118A1/de not_active Withdrawn
-
1989
- 1989-03-01 EP EP89103546A patent/EP0332930A2/de not_active Withdrawn
- 1989-03-02 JP JP1048691A patent/JPH01268679A/ja active Pending
- 1989-03-08 IL IL89535A patent/IL89535A0/xx unknown
- 1989-03-09 FI FI891123A patent/FI891123L/fi not_active Application Discontinuation
- 1989-03-09 PT PT89956A patent/PT89956A/pt not_active Application Discontinuation
- 1989-03-10 KR KR1019890002952A patent/KR890014489A/ko not_active Abandoned
- 1989-03-11 CN CN89103162A patent/CN1037335A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI891123A7 (fi) | 1989-09-12 |
| KR890014489A (ko) | 1989-10-24 |
| FI891123A0 (fi) | 1989-03-09 |
| FI891123L (fi) | 1989-09-12 |
| EP0332930A2 (de) | 1989-09-20 |
| IL89535A0 (en) | 1989-09-10 |
| CN1037335A (zh) | 1989-11-22 |
| DE3808118A1 (de) | 1989-09-21 |
| JPH01268679A (ja) | 1989-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC3A | Refusal |
Effective date: 19940422 |