PT89483A - Processo para a preparacao de derivados da 2-amino acetamida - Google Patents
Processo para a preparacao de derivados da 2-amino acetamidaInfo
- Publication number
- PT89483A PT89483A PT89483A PT8948389A PT89483A PT 89483 A PT89483 A PT 89483A PT 89483 A PT89483 A PT 89483A PT 8948389 A PT8948389 A PT 8948389A PT 89483 A PT89483 A PT 89483A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- compounds
- pharmaceutically acceptable
- acetamide derivatives
- amino acetamide
- Prior art date
Links
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical class NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14586588A | 1988-01-20 | 1988-01-20 | |
| US14594388A | 1988-01-20 | 1988-01-20 | |
| US07/145,866 US4871872A (en) | 1988-01-20 | 1988-01-20 | 2-[(2-aminoacetyl)amino]acetamide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT89483A true PT89483A (pt) | 1989-10-04 |
| PT89483B PT89483B (pt) | 1994-02-28 |
Family
ID=27386328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89483A PT89483B (pt) | 1988-01-20 | 1989-01-19 | Processo para a preparacao de derivados da 2-amino acetamida |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP0401253A1 (pt) |
| JP (1) | JPH02503089A (pt) |
| AT (1) | ATE96144T1 (pt) |
| CA (1) | CA1315477C (pt) |
| DE (1) | DE68909961T2 (pt) |
| DK (1) | DK460789A (pt) |
| IE (1) | IE890161L (pt) |
| PT (1) | PT89483B (pt) |
| WO (1) | WO1989006646A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0356035B1 (en) * | 1988-08-12 | 1996-03-13 | Astra Aktiebolag | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2449638A (en) * | 1946-05-10 | 1948-09-21 | Wyeth Corp | Substituted glycinamides |
| DE955508C (de) * | 1954-07-28 | 1957-01-03 | Cilag Ag | Verfahren zur Herstellung von antikonvulsivisch wirkenden Carbonsaeureamiden |
| GB1420067A (en) * | 1972-02-15 | 1976-01-07 | Astra Laekemedel Ab | Aryldiamides |
| SE408171B (sv) * | 1975-09-04 | 1979-05-21 | Astra Laekemedel Ab | Analogiforfarande for framstellning av nya aralkylamider av 2-aminopropropionsyra, vilka amider har framakologiska egenskaper |
-
1989
- 1989-01-10 JP JP1502245A patent/JPH02503089A/ja active Pending
- 1989-01-10 DE DE89300164T patent/DE68909961T2/de not_active Expired - Fee Related
- 1989-01-10 AT AT89300164T patent/ATE96144T1/de not_active IP Right Cessation
- 1989-01-10 WO PCT/US1989/000041 patent/WO1989006646A1/en not_active Ceased
- 1989-01-10 EP EP89902415A patent/EP0401253A1/en active Pending
- 1989-01-10 EP EP89300164A patent/EP0326240B1/en not_active Expired - Lifetime
- 1989-01-19 IE IE890161A patent/IE890161L/xx unknown
- 1989-01-19 PT PT89483A patent/PT89483B/pt active IP Right Grant
- 1989-01-20 CA CA000588803A patent/CA1315477C/en not_active Expired - Fee Related
- 1989-09-19 DK DK460789A patent/DK460789A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE68909961T2 (de) | 1994-02-10 |
| WO1989006646A1 (en) | 1989-07-27 |
| ATE96144T1 (de) | 1993-11-15 |
| EP0326240A1 (en) | 1989-08-02 |
| DK460789D0 (da) | 1989-09-19 |
| DK460789A (da) | 1989-11-20 |
| EP0401253A1 (en) | 1990-12-12 |
| PT89483B (pt) | 1994-02-28 |
| EP0326240B1 (en) | 1993-10-20 |
| CA1315477C (en) | 1993-03-30 |
| DE68909961D1 (de) | 1993-11-25 |
| JPH02503089A (ja) | 1990-09-27 |
| IE890161L (en) | 1989-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19930813 |