PT90034A - Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas - Google Patents

Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas

Info

Publication number: PT90034A
Authority: PT; Portugal
Prior art keywords: 6alkyl; hydrogen; 6alkenyl; ones; tetrahydroimidazo
Prior art date: 1988-03-18

Application number

PT90034A

Other languages

English (en)

Other versions

PT90034B (pt

Inventor

Alfons Herman Marg Raeymaekers

Michael Joseph Kukla

Henry Joseph Breslin

Josephus Ludovicus Hube Gelder

Paul Adriaan Jan Janssen

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-18

Filing date

1989-03-17

Publication date

1989-11-10

1989-03-17 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1989-11-10 Publication of PT90034A publication Critical patent/PT90034A/pt

1994-05-31 Publication of PT90034B publication Critical patent/PT90034B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT90034A 1988-03-18 1989-03-17 Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas PT90034B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888806449A GB8806449D0 (en)	1988-03-18	1988-03-18	Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones

Publications (2)

Publication Number	Publication Date
PT90034A true PT90034A (pt)	1989-11-10
PT90034B PT90034B (pt)	1994-05-31

Family

ID=10633662

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90034A PT90034B (pt)	1988-03-18	1989-03-17	Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas

Country Status (26)

Country	Link
EP (1)	EP0336466B1 (pt)
JP (1)	JP2693559B2 (pt)
KR (1)	KR0133073B1 (pt)
CN (1)	CN1031058C (pt)
AT (1)	ATE84035T1 (pt)
AU (2)	AU617435B2 (pt)
BG (1)	BG51251A3 (pt)
CA (1)	CA1310964C (pt)
DE (1)	DE68904102T2 (pt)
DK (1)	DK130989A (pt)
ES (1)	ES2053946T3 (pt)
FI (1)	FI89800C (pt)
GB (1)	GB8806449D0 (pt)
GR (1)	GR3006728T3 (pt)
HU (2)	HU206873B (pt)
IE (1)	IE63108B1 (pt)
IL (1)	IL89633A (pt)
JO (1)	JO1589B1 (pt)
MY (1)	MY104942A (pt)
NO (1)	NO167737C (pt)
NZ (1)	NZ228216A (pt)
PH (1)	PH27044A (pt)
PT (1)	PT90034B (pt)
SU (1)	SU1748647A3 (pt)
TN (1)	TNSN89039A1 (pt)
ZA (1)	ZA892062B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5270464A (en) *	1989-03-14	1993-12-14	Janssen Pharmaceutica N.V.	Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones
IL93136A (en) *	1989-02-23	1995-01-24	Janssen Pharmaceutica Nv	Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them
NZ235137A (en) *	1989-09-13	1992-02-25	Janssen Pharmaceutica Nv	Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
US5164376A (en) *	1989-10-30	1992-11-17	Hoffmann-Laroche Inc.	Method for treating retroviral infections with aryl-(2-pyrryl) keytone compound
EP0436245A1 (en) *	1989-12-27	1991-07-10	Duphar International Research B.V	Substituted 3,4-annelated benzimidazol-2(1H)-ones
US5141735A (en) *	1990-06-18	1992-08-25	Hoffman-La Roche, Inc.	Substituted amino-benzodiazepines having anitviral activity
NZ238664A (en) *	1990-07-06	1992-12-23	Janssen Pharmaceutica Nv	Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
GB9018601D0 (en) *	1990-08-24	1990-10-10	Fujisawa Pharmaceutical Co	Tricyclic compounds
DE4036552C1 (pt) *	1990-11-16	1992-02-06	Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9109557D0 (en)	1991-05-02	1991-06-26	Wellcome Found	Chemical compounds
HU221816B1 (hu) *	1991-10-11	2003-01-28	Bristol-Myers Squibb Pharma Company	Gyűrűs karbonil vegyületek, és ezeket tartalmazó gyógyászati készítmények
ATE184787T1 (de) *	1992-05-13	1999-10-15	Wellcome Found	Therapeutische kombinationen
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
MX2007002461A (es) *	2004-09-22	2008-03-13	Pfizer	Formas polimorficas y amorfas de la sal fosfato de 8-fluoro-2-{4-[metilamino)metil]fenil}-1, 3, 4, 5-tetrahidro-6h-azepino [5, 4, 3-cd]indol-6-ona.
CN101535315A (zh) *	2006-10-13	2009-09-16	辉瑞有限公司	用作家畜动物的同化激素类药的杂环化合物
CN101827597B (zh)	2007-08-20	2013-03-13	伊沃泰克国际有限责任公司	睡眠障碍的治疗

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2534257A1 (fr) *	1982-10-12	1984-04-13	Roussel Uclaf	Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire
IL93136A (en) *	1989-02-23	1995-01-24	Janssen Pharmaceutica Nv	Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them

1988
- 1988-03-18 GB GB888806449A patent/GB8806449D0/en active Pending
1989
- 1989-02-10 MY MYPI89000163A patent/MY104942A/en unknown
- 1989-03-03 NZ NZ228216A patent/NZ228216A/xx unknown
- 1989-03-08 EP EP89200575A patent/EP0336466B1/en not_active Expired - Lifetime
- 1989-03-08 ES ES89200575T patent/ES2053946T3/es not_active Expired - Lifetime
- 1989-03-08 AT AT89200575T patent/ATE84035T1/de not_active IP Right Cessation
- 1989-03-08 DE DE8989200575T patent/DE68904102T2/de not_active Expired - Fee Related
- 1989-03-13 JO JO19891589A patent/JO1589B1/en active
- 1989-03-14 JP JP1059859A patent/JP2693559B2/ja not_active Expired - Lifetime
- 1989-03-14 AU AU31310/89A patent/AU617435B2/en not_active Ceased
- 1989-03-16 BG BG087682A patent/BG51251A3/bg unknown
- 1989-03-16 HU HU911782A patent/HU206873B/hu not_active IP Right Cessation
- 1989-03-16 CA CA000593935A patent/CA1310964C/en not_active Expired - Fee Related
- 1989-03-16 IL IL8963389A patent/IL89633A/en not_active IP Right Cessation
- 1989-03-16 IE IE85189A patent/IE63108B1/en not_active IP Right Cessation
- 1989-03-16 HU HU891240A patent/HU203757B/hu not_active IP Right Cessation
- 1989-03-17 PH PH38339A patent/PH27044A/en unknown
- 1989-03-17 ZA ZA892062A patent/ZA892062B/xx unknown
- 1989-03-17 PT PT90034A patent/PT90034B/pt not_active IP Right Cessation
- 1989-03-17 SU SU894613664A patent/SU1748647A3/ru active
- 1989-03-17 FI FI891279A patent/FI89800C/fi not_active IP Right Cessation
- 1989-03-17 NO NO891176A patent/NO167737C/no unknown
- 1989-03-17 DK DK130989A patent/DK130989A/da not_active Application Discontinuation
- 1989-03-18 CN CN89101474A patent/CN1031058C/zh not_active Expired - Fee Related
- 1989-03-18 KR KR89003388A patent/KR0133073B1/ko not_active Expired - Fee Related
- 1989-03-19 TN TNTNSN89039A patent/TNSN89039A1/fr unknown
1991
- 1991-09-02 AU AU83602/91A patent/AU630575B2/en not_active Ceased
1992
- 1992-12-31 GR GR920403099T patent/GR3006728T3/el unknown

Also Published As

Publication number	Publication date
EP0336466B1 (en)	1992-12-30
FI89800C (fi)	1993-11-25
TNSN89039A1 (fr)	1991-02-04
ATE84035T1 (de)	1993-01-15
FI891279A0 (fi)	1989-03-17
DE68904102T2 (de)	1993-05-06
NO891176L (no)	1989-09-19
AU617435B2 (en)	1991-11-28
GB8806449D0 (en)	1988-04-20
GR3006728T3 (pt)	1993-06-30
AU630575B2 (en)	1992-10-29
IL89633A (en)	1994-02-27
CN1036957A (zh)	1989-11-08
MY104942A (en)	1994-07-30
IE890851L (en)	1989-09-18
HU203757B (en)	1991-09-30
HU911782D0 (en)	1991-12-30
KR0133073B1 (en)	1998-04-17
DK130989D0 (da)	1989-03-17
NZ228216A (en)	1991-01-29
ZA892062B (en)	1990-11-28
FI891279L (fi)	1989-09-19
PH27044A (en)	1993-02-01
ES2053946T3 (es)	1994-08-01
JO1589B1 (en)	1989-12-16
NO167737C (no)	1991-12-04
AU8360291A (en)	1991-11-07
SU1748647A3 (ru)	1992-07-15
BG51251A3 (bg)	1993-03-15
EP0336466A1 (en)	1989-10-11
JP2693559B2 (ja)	1997-12-24
JPH01275582A (ja)	1989-11-06
NO891176D0 (no)	1989-03-17
CN1031058C (zh)	1996-02-21
HUT52099A (en)	1990-06-28
FI89800B (fi)	1993-08-13
PT90034B (pt)	1994-05-31
IE63108B1 (en)	1995-03-22
AU3131089A (en)	1989-09-21
IL89633A0 (en)	1989-09-28
KR890014546A (ko)	1989-10-24
HU206873B (en)	1993-01-28
DE68904102D1 (de)	1993-02-11
NO167737B (no)	1991-08-26
DK130989A (da)	1989-09-19
CA1310964C (en)	1992-12-01

Publication	Publication Date	Title
AU617918B2 (en)	1991-12-05	2-aminopyrimidinone derivatives
AU3821089A (en)	1990-01-25	2-phenyl-purin-6-one derivatives for use as bronchodilators and vasodilators
AU593736B2 (en)	1990-02-15	Novel intermediates
PT90034A (pt)	1989-11-10	Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas
FI893701A0 (fi)	1989-08-04	Menetelmä antipsykoottisten 3-piperatsinyylibentsatsolijohdannaisten valmistamiseksi
PT91613A (pt)	1990-03-30	Process for the preparation of antihypertensive 3-piperidinyl-indazole derivatives
ATE97902T1 (de)	1993-12-15	Cephemverbindungen und verfahren zu ihrer herstellung.

Legal Events

Date	Code	Title	Description
1994-05-31	FG3A	Patent granted, date of granting	Effective date: 19931115
1999-09-30	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19990531

Date

Code

Title

Description

1994-05-31

FG3A

Patent granted, date of granting

Effective date: 19931115

1999-09-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990531