DK0539204T3 - Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre - Google Patents
Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyreInfo
- Publication number
- DK0539204T3 DK0539204T3 DK92309684T DK92309684T DK0539204T3 DK 0539204 T3 DK0539204 T3 DK 0539204T3 DK 92309684 T DK92309684 T DK 92309684T DK 92309684 T DK92309684 T DK 92309684T DK 0539204 T3 DK0539204 T3 DK 0539204T3
- Authority
- DK
- Denmark
- Prior art keywords
- antiviral
- deoxy
- alpha
- substituted
- neuraminic acid
- Prior art date
Links
- CERZMXAJYMMUDR-LSRLBZCKSA-N alpha-neuraminic acid Chemical class N[C@@H]1[C@@H](O)C[C@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO CERZMXAJYMMUDR-LSRLBZCKSA-N 0.000 title 1
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPK905191 | 1991-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0539204T3 true DK0539204T3 (da) | 1998-09-07 |
Family
ID=3775765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92309684T DK0539204T3 (da) | 1991-10-23 | 1992-10-22 | Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0539204B1 (da) |
| JP (1) | JP2925863B2 (da) |
| AT (1) | ATE161836T1 (da) |
| AU (1) | AU659501B2 (da) |
| CA (1) | CA2081068C (da) |
| DE (1) | DE69223914T2 (da) |
| DK (1) | DK0539204T3 (da) |
| ES (1) | ES2113413T3 (da) |
| GR (1) | GR3026218T3 (da) |
| ZA (1) | ZA928170B (da) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
| GB9220327D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
| GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
| AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
| GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
| US5561146A (en) * | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
| US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
| SI9620042A (sl) * | 1995-02-27 | 1998-12-31 | Gilead Sciences, Inc. | Novi selektivni inhibitorji virusnih ali bakterijskih neuraminidaz |
| CN101172957B (zh) * | 1995-02-27 | 2012-11-14 | 吉里德科学公司 | 新颖化合物,其合成方法及治疗用途 |
| US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| US5602277A (en) * | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
| ATE206116T1 (de) * | 1995-05-19 | 2001-10-15 | Biota Scient Management | 6-carboxamido-dihydropyran-derivate |
| GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| PT823428E (pt) * | 1996-07-22 | 2002-04-29 | Sankyo Co | Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina |
| US6451766B1 (en) | 1996-07-22 | 2002-09-17 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
| US6340702B1 (en) | 1996-07-22 | 2002-01-22 | Sankyo Company, Limited | Neuraminic acid derivatives, their preparation and their medical use |
| PT934939E (pt) * | 1996-08-13 | 2003-07-31 | Sankyo Co | Compostos de acido neuraminico |
| US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
| US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| AU711845B2 (en) * | 1996-09-10 | 1999-10-21 | Daikin Industries, Ltd. | 4-substituted-2,7-dideoxy-7-fluoro-2,3-didehydro-sialic acid compounds |
| CA2268756A1 (en) * | 1996-10-21 | 1998-04-30 | Gilead Sciences, Inc. | Piperidine compounds |
| US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
| TR199901081T2 (xx) * | 1996-11-14 | 1999-08-23 | Biota Scientific Management Pty.Ltd. | Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler. |
| US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| TW480247B (en) * | 1997-12-12 | 2002-03-21 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
| US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
| US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
| US6608081B2 (en) | 1999-08-12 | 2003-08-19 | Ortho-Mcneil Pharmaceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
| WO2002092555A1 (en) * | 2001-05-11 | 2002-11-21 | Sankyo Company, Limited | Sialic acid derivatives |
| PL215419B1 (pl) | 2003-02-10 | 2013-12-31 | Nippon Catalytic Chem Ind | Srodek pochlaniajacy wode |
| CA2675934C (en) | 2007-01-23 | 2015-09-15 | Therapicon Srl | Antiviral compounds |
| JPWO2009004899A1 (ja) * | 2007-06-15 | 2010-08-26 | 国立大学法人北海道大学 | シアリダーゼ阻害剤 |
| EP2358695B1 (en) | 2008-11-28 | 2014-07-02 | Cipla Limited | Process for preparing zanamivir and intermediates for use in the process |
| EA201101564A1 (ru) | 2009-05-15 | 2012-07-30 | Редкс Фарма Лимитед | Редокс производные лекарственных средств |
| IT1396620B1 (it) | 2009-11-25 | 2012-12-14 | Therapicon Srl | Analoghi chimerici |
| EP2678324A1 (en) | 2011-02-24 | 2014-01-01 | Cadila Healthcare Limited | Process for the preparation of zanamivir |
| DE102011117128A1 (de) * | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP249A (en) * | 1990-04-24 | 1993-03-17 | Biota Scient Management Pty Ltd | Anti-viral compounds. |
| GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
-
1992
- 1992-10-21 CA CA002081068A patent/CA2081068C/en not_active Expired - Fee Related
- 1992-10-21 AU AU27242/92A patent/AU659501B2/en not_active Ceased
- 1992-10-22 ZA ZA928170A patent/ZA928170B/xx unknown
- 1992-10-22 DE DE69223914T patent/DE69223914T2/de not_active Expired - Lifetime
- 1992-10-22 ES ES92309684T patent/ES2113413T3/es not_active Expired - Lifetime
- 1992-10-22 EP EP92309684A patent/EP0539204B1/en not_active Expired - Lifetime
- 1992-10-22 AT AT92309684T patent/ATE161836T1/de not_active IP Right Cessation
- 1992-10-22 DK DK92309684T patent/DK0539204T3/da active
- 1992-10-23 JP JP4309626A patent/JP2925863B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-25 GR GR980400397T patent/GR3026218T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3026218T3 (en) | 1998-05-29 |
| AU659501B2 (en) | 1995-05-18 |
| CA2081068A1 (en) | 1993-04-24 |
| EP0539204B1 (en) | 1998-01-07 |
| ZA928170B (en) | 1993-11-15 |
| ATE161836T1 (de) | 1998-01-15 |
| CA2081068C (en) | 2005-11-29 |
| JPH0625209A (ja) | 1994-02-01 |
| HK1015137A1 (en) | 1999-10-08 |
| DE69223914T2 (de) | 1998-04-30 |
| EP0539204A1 (en) | 1993-04-28 |
| JP2925863B2 (ja) | 1999-07-28 |
| ES2113413T3 (es) | 1998-05-01 |
| AU2724292A (en) | 1993-04-29 |
| DE69223914D1 (de) | 1998-02-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0539204T3 (da) | Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre | |
| FI872864A0 (fi) | Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi | |
| ES2095432T3 (es) | Derivados de 2,4-tiazolidin-diona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| ES2074846T3 (es) | Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. | |
| ES2081187T3 (es) | Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| DE19875016I2 (de) | Nukleosidanalogen enthaltende Antiviren-Zubereitungen. | |
| ES2123039T3 (es) | Nuevas 3-(hidroxi-bencilidenil)-indolin-2-onas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| DE68917485D1 (de) | Pyridazinon-Derivate und diese enthaltende pharmazeutische Zubereitungen. | |
| MX9203417A (es) | Compuestos de diarilo antiateroescleroticos. | |
| ES2118203T3 (es) | Nuevos derivados benzopiranicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| ES2105362T3 (es) | Nuevos derivados de acidos quinolon- y naftiridoncarboxilicos. | |
| SE8404065D0 (sv) | Novel biologically active compounds | |
| NO923721D0 (no) | 4-desoksy-4-epipodophyllotoxin-derivat eller farmasoeytiskakseptabelt salt derav | |
| IT1224405B (it) | Composti attivi sul sistema cardiovascolare | |
| SE8600658D0 (sv) | Novel composition of matter | |
| ES2111871T3 (es) | Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| DE69300296D1 (de) | Thiochromanderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. | |
| ES2076054T3 (es) | Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| ATE123497T1 (de) | Substituierte pyridin-verbindungen, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
| ES2104295T3 (es) | Derivados ciclopeptidicos de la angiopeptina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| DK0418990T3 (da) | 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler | |
| ES2065192T3 (es) | Nuevos nicotinatos de diacil-glicerol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| ITMI911845A1 (it) | Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico. | |
| IT1224404B (it) | Composti attivi sul sistema cardiovascolare | |
| ES2123038T3 (es) | Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. |