PT84109B - Processo para a preparacao de benzazepinas condensadas - Google Patents

Processo para a preparacao de benzazepinas condensadas

Info

Publication number: PT84109B
Authority: PT; Portugal
Prior art keywords: benzazepines; condensed; preparation; condensed benzazepines
Prior art date: 1986-01-16

Application number

PT84109A

Other languages

English (en)

Other versions

PT84109A (en

Inventor

Wei Kong Chang

Joel Gilbert Berger

Elijah Herman Gold

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-16

Filing date

1987-01-15

Publication date

1989-07-31

1987-01-15 Application filed by Schering Corp filed Critical Schering Corp

1987-02-01 Publication of PT84109A publication Critical patent/PT84109A/pt

1989-07-31 Publication of PT84109B publication Critical patent/PT84109B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT84109A 1986-01-16 1987-01-15 Processo para a preparacao de benzazepinas condensadas PT84109B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US82047186A	1986-01-16	1986-01-16

Publications (2)

Publication Number	Publication Date
PT84109A PT84109A (en)	1987-02-01
PT84109B true PT84109B (pt)	1989-07-31

Family

ID=25230864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT84109A PT84109B (pt)	1986-01-16	1987-01-15	Processo para a preparacao de benzazepinas condensadas

Country Status (19)

Country	Link
EP (2)	EP0254737B1 (pt)
JP (1)	JPH0681745B2 (pt)
KR (1)	KR900007781B1 (pt)
AU (1)	AU588080B2 (pt)
CA (1)	CA1333485C (pt)
CS (1)	CS414091A3 (pt)
DK (1)	DK164161C (pt)
ES (1)	ES2031834T3 (pt)
FI (1)	FI83512C (pt)
GR (1)	GR3000994T3 (pt)
HU (1)	HU199805B (pt)
IE (1)	IE59651B1 (pt)
IL (2)	IL81268A0 (pt)
NZ (1)	NZ218953A (pt)
OA (1)	OA08660A (pt)
PT (1)	PT84109B (pt)
SG (1)	SG128692G (pt)
WO (1)	WO1987004430A2 (pt)
ZA (1)	ZA87291B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4973586A (en)	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
ATE78467T1 (de) *	1987-07-15	1992-08-15	Schering Corp	Kondensierte benzazepine.
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
AU624854B2 (en) *	1988-07-29	1992-06-25	Schering Corporation	A process for the enantiospecific synthesis of intermediates for hexahydro-benzo(d)naphtho(2,1-b)azepines
US5091526A (en) *	1988-07-29	1992-02-25	Schering Corporation	Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
US5104814A (en) *	1988-11-22	1992-04-14	Schering Corporation	Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) *	1989-01-24	1991-05-24	Lipha	Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
EP0513174B1 (en) *	1990-02-02	1995-08-16	Schering Corporation	4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US5461147A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461148A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) *	1993-09-27	1995-10-31	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) *	2000-03-22	2003-04-09	Yakult Honsha Kk	Procedimiento para preparar camptotecina
EP2316469A1 (en)	2002-02-22	2011-05-04	Shire LLC	Delivery system and methods for protecting and administering dextroamphetamine
MXPA05002249A (es)	2002-08-29	2005-06-08	Schering Corp	Antagonistas selectivos del receptor d1/d5 para el tratamiento de obesidad y trastornos del sistema nervioso central.
CN1823059A (zh) *	2003-05-22	2006-08-23	先灵公司	作为治疗肥胖和CNS疾病的选择性D<sub>1</sub>/D<sub>5</sub>受体拮抗剂的5－H－苯并[D]萘并[2,1－B]氮杂䓬衍生物
US8586634B2 (en)	2007-06-15	2013-11-19	University Of Florida Research Foundation, Inc.	Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3393192A (en) *	1965-04-26	1968-07-16	Schering Corp	Novel benzazepines
GB1118688A (en)	1967-02-17	1968-07-03	Scherico Ltd	Novel benzazepines and process for making same
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US3609138A (en)	1967-12-22	1971-09-28	Ciba Geigy Corp	1-aryl-3-benzazepines
FR2137627A1 (pt) *	1971-05-10	1972-12-29	Hoffmann La Roche
US3939165A (en) *	1974-11-14	1976-02-17	Morton-Norwich Products, Inc.	5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en)	1975-07-02	1977-03-08	Smithkline Corporation	Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en)	1979-04-27	1981-08-18	Schering Corporation	7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en)	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1987
- 1987-01-14 WO PCT/US1987/000042 patent/WO1987004430A2/en not_active Ceased
- 1987-01-14 KR KR1019870700836A patent/KR900007781B1/ko not_active Expired
- 1987-01-14 EP EP87900939A patent/EP0254737B1/en not_active Expired - Lifetime
- 1987-01-14 AU AU68920/87A patent/AU588080B2/en not_active Ceased
- 1987-01-14 HU HU87914A patent/HU199805B/hu not_active IP Right Cessation
- 1987-01-14 JP JP62500944A patent/JPH0681745B2/ja not_active Expired - Lifetime
- 1987-01-15 IL IL81268A patent/IL81268A0/xx not_active IP Right Cessation
- 1987-01-15 ES ES198787100446T patent/ES2031834T3/es not_active Expired - Lifetime
- 1987-01-15 IL IL103007A patent/IL103007A/xx not_active IP Right Cessation
- 1987-01-15 ZA ZA87291A patent/ZA87291B/xx unknown
- 1987-01-15 PT PT84109A patent/PT84109B/pt not_active IP Right Cessation
- 1987-01-15 CA CA000527422A patent/CA1333485C/en not_active Expired - Fee Related
- 1987-01-15 EP EP87100446A patent/EP0230270B1/en not_active Expired - Lifetime
- 1987-01-15 NZ NZ218953A patent/NZ218953A/xx unknown
- 1987-01-20 IE IE11287A patent/IE59651B1/en not_active IP Right Cessation
- 1987-09-14 DK DK479087A patent/DK164161C/da not_active IP Right Cessation
- 1987-09-15 FI FI874006A patent/FI83512C/fi not_active IP Right Cessation
- 1987-09-15 OA OA59194A patent/OA08660A/xx unknown
1990
- 1990-10-29 GR GR90400833T patent/GR3000994T3/el unknown
1991
- 1991-12-30 CS CS914140A patent/CS414091A3/cs unknown
1992
- 1992-12-17 SG SG1286/92A patent/SG128692G/en unknown

Also Published As

Publication number	Publication date
HU199805B (en)	1990-03-28
EP0230270A2 (en)	1987-07-29
OA08660A (en)	1988-11-30
ES2031834T3 (es)	1993-01-01
DK164161B (da)	1992-05-18
DK479087A (da)	1987-09-14
GR3000994T3 (en)	1991-12-10
JPH0681745B2 (ja)	1994-10-19
FI874006A0 (fi)	1987-09-15
KR900007781B1 (ko)	1990-10-20
AU6892087A (en)	1987-08-14
IE870112L (en)	1987-07-16
PT84109A (en)	1987-02-01
CS414091A3 (en)	1992-05-13
FI874006L (fi)	1987-09-15
AU588080B2 (en)	1989-09-07
IE59651B1 (en)	1994-03-09
SG128692G (en)	1993-03-12
HUT48600A (en)	1989-06-28
EP0254737A1 (en)	1988-02-03
DK164161C (da)	1992-10-26
WO1987004430A3 (en)	1988-03-24
FI83512B (fi)	1991-04-15
NZ218953A (en)	1990-03-27
EP0230270B1 (en)	1990-08-01
CA1333485C (en)	1994-12-13
IL81268A0 (en)	1987-08-31
DK479087D0 (da)	1987-09-14
EP0254737B1 (en)	1990-07-25
KR880700794A (ko)	1988-04-12
WO1987004430A2 (en)	1987-07-30
IL103007A (en)	1993-07-08
FI83512C (fi)	1991-07-25
ZA87291B (en)	1987-11-25
EP0230270A3 (en)	1987-10-21
JPS63502348A (ja)	1988-09-08

Publication	Publication Date	Title
PT86312A (pt)	1989-01-17	Processo para a preparacao de fibras superabsorventes
BR8802484A (pt)	1988-12-20	Processo para a preparacao de isocianatos
PT84806B (pt)	1989-12-29	Processo para a preparacao de benzopiranos
PT84316B (pt)	1989-09-14	Processo para a preparacao de cicloalcano {1,2 -b} indole-sulfamidas
PT89264A (pt)	1989-12-29	Processo para a preparacao de compostos azabiciclicos
PT84774B (pt)	1989-12-29	Processo para a preparacao de pirimidinas substituidas
PT92786A (pt)	1990-07-31	Processo para a preparacao de compostos de tiazol
PT84109B (pt)	1989-07-31	Processo para a preparacao de benzazepinas condensadas
BR8707028A (pt)	1988-08-09	Processo para a preparacao de mercaptometilfenois
BR8801269A (pt)	1988-10-25	Processo para a preparacao de um composto de ciano-imidazol
PT84778B (pt)	1989-12-29	Processo para a preparacao de compostos derivados de tiazolotriazol
PT84072B (pt)	1989-07-31	Processo para a preparacao de esteroides aminoglicosidicos
BR8702112A (pt)	1988-02-09	Processo para a preparacao de um derivado de pirazol pirimidina
PT89039A (pt)	1988-12-01	Processo para a preparacao de l-ramnose
PT84780B (pt)	1989-12-29	Processo para a preparacao de compostos derivados de triazolopirimidina
BR9001503A (pt)	1991-04-16	Processo para a preparacao de alquil-halogenossilanos
BR8803678A (pt)	1989-02-14	Processo para a preparacao de polieteramidas
PT84233B (pt)	1989-09-14	Processo aperfeicoado para a resolucao de 1-aminoindanos
PT89056A (pt)	1989-11-30	Processo para a preparacao de hidroxilaminas substituidas
BR8706408A (pt)	1988-07-12	Processo para a preparacao de aldeidos
BR8806351A (pt)	1989-08-22	Processo para a preparacao de fenil-ureias
BR8703546A (pt)	1988-03-22	Processo para a preparacao de ticl4
PT94890A (pt)	1991-04-18	Processo para a preparacao de compostos azofenilicos
BR8704522A (pt)	1988-04-19	Processo para a preparacao de tetracloreto de titanio
PT89237A (pt)	1989-12-29	Processo para a preparacao de compostos beta-lactamicos

Legal Events

Date	Code	Title	Description
1996-11-29	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960731

Date

Code

Title

Description

1996-11-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960731