FI874006A0 - Fusionerade benzazepiner. - Google Patents

Fusionerade benzazepiner.

Info

Publication number: FI874006A0
Authority: FI; Finland
Prior art keywords: fusionerade; benzazepiner; benzazepiner fusionerade
Prior art date: 1986-01-16

Application number

FI874006A

Other languages

English (en)

Other versions

FI83512C (fi

FI83512B (fi

FI874006L (fi

Inventor

Joel Gilbert Berger

Wei Kong Chang

Elijah Herman Gold

John Welch Clader

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-16

Filing date

1987-09-15

Publication date

1987-09-15

1987-09-15 Application filed by Schering Corp filed Critical Schering Corp

1987-09-15 Publication of FI874006A0 publication Critical patent/FI874006A0/fi

1987-09-15 Publication of FI874006L publication Critical patent/FI874006L/fi

1991-04-15 Application granted granted Critical

1991-04-15 Publication of FI83512B publication Critical patent/FI83512B/fi

1991-07-25 Publication of FI83512C publication Critical patent/FI83512C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI874006A 1986-01-16 1987-09-15 Foerfarande foer framstaellning av farmakologiskt vaerdefulla fusionerade bensazepinfoereningar. FI83512C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US82047186A	1986-01-16	1986-01-16
US82047186		1986-01-16
US8700042		1987-01-14
PCT/US1987/000042 WO1987004430A2 (en)	1986-01-16	1987-01-14	Fused benzazepines

Publications (4)

Publication Number	Publication Date
FI874006A0 true FI874006A0 (fi)	1987-09-15
FI874006L FI874006L (fi)	1987-09-15
FI83512B FI83512B (fi)	1991-04-15
FI83512C FI83512C (fi)	1991-07-25

Family

ID=25230864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI874006A FI83512C (fi)	1986-01-16	1987-09-15	Foerfarande foer framstaellning av farmakologiskt vaerdefulla fusionerade bensazepinfoereningar.

Country Status (19)

Country	Link
EP (2)	EP0254737B1 (fi)
JP (1)	JPH0681745B2 (fi)
KR (1)	KR900007781B1 (fi)
AU (1)	AU588080B2 (fi)
CA (1)	CA1333485C (fi)
CS (1)	CS414091A3 (fi)
DK (1)	DK164161C (fi)
ES (1)	ES2031834T3 (fi)
FI (1)	FI83512C (fi)
GR (1)	GR3000994T3 (fi)
HU (1)	HU199805B (fi)
IE (1)	IE59651B1 (fi)
IL (2)	IL103007A (fi)
NZ (1)	NZ218953A (fi)
OA (1)	OA08660A (fi)
PT (1)	PT84109B (fi)
SG (1)	SG128692G (fi)
WO (1)	WO1987004430A2 (fi)
ZA (1)	ZA87291B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4973586A (en)	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
ATE78467T1 (de) *	1987-07-15	1992-08-15	Schering Corp	Kondensierte benzazepine.
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
US5091526A (en) *	1988-07-29	1992-02-25	Schering Corporation	Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
AU624854B2 (en) *	1988-07-29	1992-06-25	Schering Corporation	A process for the enantiospecific synthesis of intermediates for hexahydro-benzo(d)naphtho(2,1-b)azepines
US5104814A (en) *	1988-11-22	1992-04-14	Schering Corporation	Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) *	1989-01-24	1991-05-24	Lipha	Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
US5362728A (en) *	1990-02-02	1994-11-08	Schering Corporation	4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds
US5463051A (en) *	1993-09-27	1995-10-31	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461147A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461148A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es)	2000-03-22	2003-04-09	Yakult Honsha Kk	Procedimiento para preparar camptotecina
CA2477088A1 (en)	2002-02-22	2003-10-02	New River Pharmaceuticals Inc.	Active agent delivery systems and methods for protecting and administering active agents
ATE396996T1 (de)	2002-08-29	2008-06-15	Schering Corp	Selektive d1/d5 rezeptorantagonisten zur behandlung von fettleibigkeit und von zns störungen
JP2006526021A (ja) *	2003-05-22	2006-11-16	シェーリング　コーポレイション	肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体
EP2164324B1 (en)	2007-06-15	2014-08-13	University Of Florida Research Foundation	Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3393192A (en) *	1965-04-26	1968-07-16	Schering Corp	Novel benzazepines
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
GB1118688A (en)	1967-02-17	1968-07-03	Scherico Ltd	Novel benzazepines and process for making same
US3609138A (en)	1967-12-22	1971-09-28	Ciba Geigy Corp	1-aryl-3-benzazepines
IL39380A0 (en) *	1971-05-10	1972-07-26	Sparamedica Ag	Benzazepine derivatives and their preparation
US3939165A (en) *	1974-11-14	1976-02-17	Morton-Norwich Products, Inc.	5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en)	1975-07-02	1977-03-08	Smithkline Corporation	Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en)	1979-04-27	1981-08-18	Schering Corporation	7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en)	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1987
- 1987-01-14 JP JP62500944A patent/JPH0681745B2/ja not_active Expired - Lifetime
- 1987-01-14 EP EP87900939A patent/EP0254737B1/en not_active Expired - Lifetime
- 1987-01-14 HU HU87914A patent/HU199805B/hu not_active IP Right Cessation
- 1987-01-14 KR KR1019870700836A patent/KR900007781B1/ko not_active Expired
- 1987-01-14 WO PCT/US1987/000042 patent/WO1987004430A2/en not_active Ceased
- 1987-01-14 AU AU68920/87A patent/AU588080B2/en not_active Ceased
- 1987-01-15 IL IL103007A patent/IL103007A/xx not_active IP Right Cessation
- 1987-01-15 ZA ZA87291A patent/ZA87291B/xx unknown
- 1987-01-15 CA CA000527422A patent/CA1333485C/en not_active Expired - Fee Related
- 1987-01-15 PT PT84109A patent/PT84109B/pt not_active IP Right Cessation
- 1987-01-15 NZ NZ218953A patent/NZ218953A/xx unknown
- 1987-01-15 IL IL81268A patent/IL81268A0/xx not_active IP Right Cessation
- 1987-01-15 ES ES198787100446T patent/ES2031834T3/es not_active Expired - Lifetime
- 1987-01-15 EP EP87100446A patent/EP0230270B1/en not_active Expired - Lifetime
- 1987-01-20 IE IE11287A patent/IE59651B1/en not_active IP Right Cessation
- 1987-09-14 DK DK479087A patent/DK164161C/da not_active IP Right Cessation
- 1987-09-15 OA OA59194A patent/OA08660A/xx unknown
- 1987-09-15 FI FI874006A patent/FI83512C/fi not_active IP Right Cessation
1990
- 1990-10-29 GR GR90400833T patent/GR3000994T3/el unknown
1991
- 1991-12-30 CS CS914140A patent/CS414091A3/cs unknown
1992
- 1992-12-17 SG SG1286/92A patent/SG128692G/en unknown

Also Published As

Publication number	Publication date
PT84109A (en)	1987-02-01
AU6892087A (en)	1987-08-14
DK479087A (da)	1987-09-14
DK164161C (da)	1992-10-26
AU588080B2 (en)	1989-09-07
PT84109B (pt)	1989-07-31
ES2031834T3 (es)	1993-01-01
HU199805B (en)	1990-03-28
HUT48600A (en)	1989-06-28
DK479087D0 (da)	1987-09-14
FI83512C (fi)	1991-07-25
NZ218953A (en)	1990-03-27
KR900007781B1 (ko)	1990-10-20
WO1987004430A3 (en)	1988-03-24
EP0230270A3 (en)	1987-10-21
OA08660A (en)	1988-11-30
SG128692G (en)	1993-03-12
CS414091A3 (en)	1992-05-13
EP0254737A1 (en)	1988-02-03
WO1987004430A2 (en)	1987-07-30
ZA87291B (en)	1987-11-25
CA1333485C (en)	1994-12-13
JPH0681745B2 (ja)	1994-10-19
JPS63502348A (ja)	1988-09-08
KR880700794A (ko)	1988-04-12
IE59651B1 (en)	1994-03-09
EP0254737B1 (en)	1990-07-25
IL81268A0 (en)	1987-08-31
DK164161B (da)	1992-05-18
GR3000994T3 (en)	1991-12-10
FI83512B (fi)	1991-04-15
FI874006L (fi)	1987-09-15
EP0230270A2 (en)	1987-07-29
EP0230270B1 (en)	1990-08-01
IL103007A (en)	1993-07-08
IE870112L (en)	1987-07-16

Publication	Publication Date	Title
DE3767169D1 (de)	1991-02-14	Sportschuh.
ATE70057T1 (de)	1991-12-15	Antitumormittel.
ATE57924T1 (de)	1990-11-15	3-aryloxy-3-substituierte-propanamine.
DE3764043D1 (de)	1990-09-06	Alkylendiamine.
ATE63533T1 (de)	1991-06-15	Xylolisomerisierung.
FI881795A0 (fi)	1988-04-18	Munstycke foer laserbehandling.
FI874006A0 (fi)	1987-09-15	Fusionerade benzazepiner.
DE3771271D1 (de)	1991-08-14	Fluorphthalimide.
FI860054A0 (fi)	1986-01-07	Motionsanordning.
DE3763648D1 (de)	1990-08-16	Rollski.
FI872767A0 (fi)	1987-06-22	Stereosaendningsanordning.
FI861938A0 (fi)	1986-05-09	Ramkonstruktion foer en borrmaskin.
DE3770459D1 (de)	1991-07-04	3-halogensuccinimide.
DE3766410D1 (de)	1991-01-10	Methylalkylcyclosiloxane.
DE3669032D1 (de)	1990-03-22	Okulopressionsgeraet.
FI860072A0 (fi)	1986-01-08	Mataranordning foer en spannmaolstork.
FI875429A0 (fi)	1987-12-10	Vaetskebehaollare.
FI851776L (fi)	1986-11-07	Elkandelaber.
FI873556A7 (fi)	1988-02-21	Pyridiniofoereningar.
NO870175D0 (no)	1987-01-15	Vasopressinforbindelser.
FI77957B (fi)	1989-01-31	Taendnings- och matarkoppling foer lyslampor.
FI77951B (fi)	1989-01-31	Foergreningsklaemma foer en sektorformig stomledare.
FI77950B (fi)	1989-01-31	Foergreningsklaemma foer en sektorformig kapad huvudledning.
FI73944B (fi)	1987-08-31	Rullningsanordning foer pappersbana.
ATE48604T1 (de)	1989-12-15	Sulfidoxymolybden-dialkylphosphorodithioate.

Legal Events

Date	Code	Title	Description
1996-08-23	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: SCHERING CORPORATION