PT1347974E - Derivados de aminotriazolopiridina como ligandos dos receptores da adenosina - Google Patents
Derivados de aminotriazolopiridina como ligandos dos receptores da adenosinaInfo
- Publication number
- PT1347974E PT1347974E PT01991804T PT01991804T PT1347974E PT 1347974 E PT1347974 E PT 1347974E PT 01991804 T PT01991804 T PT 01991804T PT 01991804 T PT01991804 T PT 01991804T PT 1347974 E PT1347974 E PT 1347974E
- Authority
- PT
- Portugal
- Prior art keywords
- aminotriazolopyridine
- derivatives
- receptor ligands
- adenosin
- adenosin receptor
- Prior art date
Links
- KGUHUVQIJHGHLX-UHFFFAOYSA-N 2h-triazolo[4,5-b]pyridin-5-amine Chemical class NC1=CC=C2NN=NC2=N1 KGUHUVQIJHGHLX-UHFFFAOYSA-N 0.000 title 1
- OIRDTQYFTABQOQ-KQYNXXCUSA-N Adenosine Natural products C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00127567 | 2000-12-15 | ||
| PCT/EP2001/014399 WO2002048145A1 (en) | 2000-12-15 | 2001-12-07 | Aminotriazolopyridiine derivatives as adenosine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1347974E true PT1347974E (pt) | 2005-02-28 |
Family
ID=8170683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01991804T PT1347974E (pt) | 2000-12-15 | 2001-12-07 | Derivados de aminotriazolopiridina como ligandos dos receptores da adenosina |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6506772B1 (pt) |
| EP (1) | EP1347974B1 (pt) |
| JP (1) | JP4049672B2 (pt) |
| KR (1) | KR100540628B1 (pt) |
| CN (1) | CN1221551C (pt) |
| AR (1) | AR031799A1 (pt) |
| AT (1) | ATE281456T1 (pt) |
| AU (2) | AU2002231674B2 (pt) |
| BR (1) | BR0116193A (pt) |
| CA (1) | CA2437006C (pt) |
| DE (1) | DE60106974T2 (pt) |
| DK (1) | DK1347974T3 (pt) |
| ES (1) | ES2230387T3 (pt) |
| GT (1) | GT200100253A (pt) |
| MX (1) | MXPA03005334A (pt) |
| PA (1) | PA8534701A1 (pt) |
| PE (1) | PE20020666A1 (pt) |
| PT (1) | PT1347974E (pt) |
| UY (1) | UY27074A1 (pt) |
| WO (1) | WO2002048145A1 (pt) |
| ZA (1) | ZA200304481B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4101755B2 (ja) * | 2001-10-08 | 2008-06-18 | エフ．ホフマン−ラ ロシュ アーゲー | ８−アミノ−〔１，２，４〕トリアゾロ〔１，５−ａ〕ピリジン−６−カルボン酸アミド |
| AU2003270701B2 (en) * | 2002-10-31 | 2009-11-12 | Amgen Inc. | Antiinflammation agents |
| CN103880827B (zh) | 2004-07-15 | 2017-01-04 | 阿尔巴尼分子研究公司 | 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用 |
| WO2008006540A1 (en) * | 2006-07-12 | 2008-01-17 | Syngenta Participations Ag | Triazolopyridine derivatives as herbicides |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| US8815894B2 (en) * | 2009-05-12 | 2014-08-26 | Bristol-Myers Squibb Company | Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof |
| KR101830447B1 (ko) * | 2009-05-12 | 2018-02-20 | 알바니 몰레큘라 리써치, 인크. | 7-(［1,2,4］트리아졸로［1,5-α］피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도 |
| EP2429295B1 (en) | 2009-05-12 | 2013-12-25 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
| EP2757882B1 (en) | 2011-09-22 | 2020-11-04 | Merck Sharp & Dohme Corp. | Imidazopyridyl compounds as aldosterone synthase inhibitors |
| WO2013043520A1 (en) * | 2011-09-22 | 2013-03-28 | Merck Sharp & Dohme Corp. | Triazolopyridyl compounds as aldosterone synthase inhibitors |
| JP7399589B2 (ja) * | 2018-09-12 | 2023-12-18 | 日本化薬株式会社 | 有害生物防除剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5356894A (en) | 1990-05-29 | 1994-10-18 | Rodney Peter W | Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist |
| GB9226735D0 (en) | 1992-12-22 | 1993-02-17 | Ici Plc | Azole derivatives |
| AU2639299A (en) | 1998-02-24 | 1999-09-15 | Kyowa Hakko Kogyo Co. Ltd. | Remedies/preventives for parkinson's disease |
| US6355653B1 (en) | 1999-09-06 | 2002-03-12 | Hoffmann-La Roche Inc. | Amino-triazolopyridine derivatives |
-
2001
- 2001-11-30 US US09/998,323 patent/US6506772B1/en not_active Expired - Fee Related
- 2001-12-07 WO PCT/EP2001/014399 patent/WO2002048145A1/en not_active Ceased
- 2001-12-07 EP EP01991804A patent/EP1347974B1/en not_active Expired - Lifetime
- 2001-12-07 MX MXPA03005334A patent/MXPA03005334A/es active IP Right Grant
- 2001-12-07 DE DE60106974T patent/DE60106974T2/de not_active Expired - Lifetime
- 2001-12-07 CN CNB018220304A patent/CN1221551C/zh not_active Expired - Fee Related
- 2001-12-07 PT PT01991804T patent/PT1347974E/pt unknown
- 2001-12-07 ES ES01991804T patent/ES2230387T3/es not_active Expired - Lifetime
- 2001-12-07 AU AU2002231674A patent/AU2002231674B2/en not_active Ceased
- 2001-12-07 CA CA002437006A patent/CA2437006C/en not_active Expired - Fee Related
- 2001-12-07 JP JP2002549676A patent/JP4049672B2/ja not_active Expired - Fee Related
- 2001-12-07 AT AT01991804T patent/ATE281456T1/de active
- 2001-12-07 BR BR0116193-8A patent/BR0116193A/pt not_active Application Discontinuation
- 2001-12-07 AU AU3167402A patent/AU3167402A/xx active Pending
- 2001-12-07 DK DK01991804T patent/DK1347974T3/da active
- 2001-12-07 KR KR1020037008004A patent/KR100540628B1/ko not_active Expired - Fee Related
- 2001-12-12 AR ARP010105765A patent/AR031799A1/es unknown
- 2001-12-12 PA PA20018534701A patent/PA8534701A1/es unknown
- 2001-12-12 PE PE2001001245A patent/PE20020666A1/es not_active Application Discontinuation
- 2001-12-14 UY UY27074A patent/UY27074A1/es not_active Application Discontinuation
- 2001-12-14 GT GT200100253A patent/GT200100253A/es unknown
-
2003
- 2003-06-09 ZA ZA200304481A patent/ZA200304481B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002231674B2 (en) | 2006-07-06 |
| ES2230387T3 (es) | 2005-05-01 |
| MXPA03005334A (es) | 2004-04-02 |
| ATE281456T1 (de) | 2004-11-15 |
| DK1347974T3 (da) | 2005-03-14 |
| CN1486314A (zh) | 2004-03-31 |
| KR20030061446A (ko) | 2003-07-18 |
| KR100540628B1 (ko) | 2006-01-11 |
| DE60106974D1 (de) | 2004-12-09 |
| EP1347974A1 (en) | 2003-10-01 |
| WO2002048145A1 (en) | 2002-06-20 |
| US6506772B1 (en) | 2003-01-14 |
| CA2437006A1 (en) | 2002-06-20 |
| DE60106974T2 (de) | 2005-11-03 |
| PA8534701A1 (es) | 2002-08-26 |
| BR0116193A (pt) | 2003-09-23 |
| PE20020666A1 (es) | 2002-07-27 |
| CA2437006C (en) | 2009-10-27 |
| GT200100253A (es) | 2002-07-31 |
| ZA200304481B (en) | 2004-09-09 |
| CN1221551C (zh) | 2005-10-05 |
| EP1347974B1 (en) | 2004-11-03 |
| JP4049672B2 (ja) | 2008-02-20 |
| AR031799A1 (es) | 2003-10-01 |
| JP2004521096A (ja) | 2004-07-15 |
| AU3167402A (en) | 2002-06-24 |
| UY27074A1 (es) | 2002-07-31 |
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