DE60106974D1 - Aminotriazolopyridinderivate als adenosinrezeptorliganden - Google Patents

Aminotriazolopyridinderivate als adenosinrezeptorliganden

Info

Publication number: DE60106974D1
Authority: DE; Germany
Prior art keywords: aminotriazolopyridine; derivatives; receptor ligands; adenosine receptor; adenosine
Prior art date: 2000-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60106974T

Other languages

English (en)

Other versions

DE60106974T2 (de

Inventor

Bernd Brodbeck

Matthias Heinrich Nettekoven

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-15

Filing date

2001-12-07

Publication date

2004-12-09

2001-12-07 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

2004-12-09 Publication of DE60106974D1 publication Critical patent/DE60106974D1/de

2005-11-03 Application granted granted Critical

2005-11-03 Publication of DE60106974T2 publication Critical patent/DE60106974T2/de

2021-12-08 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DE60106974T 2000-12-15 2001-12-07 Aminotriazolopyridinderivate als adenosinrezeptorliganden Expired - Lifetime DE60106974T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP00127567		2000-12-15
EP00127567		2000-12-15
PCT/EP2001/014399 WO2002048145A1 (en)	2000-12-15	2001-12-07	Aminotriazolopyridiine derivatives as adenosine receptor ligands

Publications (2)

Publication Number	Publication Date
DE60106974D1 true DE60106974D1 (de)	2004-12-09
DE60106974T2 DE60106974T2 (de)	2005-11-03

Family

ID=8170683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60106974T Expired - Lifetime DE60106974T2 (de)	2000-12-15	2001-12-07	Aminotriazolopyridinderivate als adenosinrezeptorliganden

Country Status (21)

Country	Link
US (1)	US6506772B1 (de)
EP (1)	EP1347974B1 (de)
JP (1)	JP4049672B2 (de)
KR (1)	KR100540628B1 (de)
CN (1)	CN1221551C (de)
AR (1)	AR031799A1 (de)
AT (1)	ATE281456T1 (de)
AU (2)	AU3167402A (de)
BR (1)	BR0116193A (de)
CA (1)	CA2437006C (de)
DE (1)	DE60106974T2 (de)
DK (1)	DK1347974T3 (de)
ES (1)	ES2230387T3 (de)
GT (1)	GT200100253A (de)
MX (1)	MXPA03005334A (de)
PA (1)	PA8534701A1 (de)
PE (1)	PE20020666A1 (de)
PT (1)	PT1347974E (de)
UY (1)	UY27074A1 (de)
WO (1)	WO2002048145A1 (de)
ZA (1)	ZA200304481B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL370067A1 (en) *	2001-10-08	2005-05-16	F.Hoffmann-La Roche Ag	8-amino-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylic acid amide
CA2502429A1 (en) *	2002-10-31	2004-05-21	Amgen Inc.	Antiinflammation agents
KR101389246B1 (ko)	2004-07-15	2014-04-24	브리스톨-마이어스스퀴브컴파니	아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및 이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
EP2046788A1 (de) *	2006-07-12	2009-04-15	Syngeta Participations AG	Triazolopyridinderivate als herbizide
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
CN102638982B (zh) *	2009-05-12	2015-07-08	百时美施贵宝公司	(S)-7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉的晶型及其用途
CN102458123A (zh) *	2009-05-12	2012-05-16	阿尔巴尼分子研究公司	芳基、杂芳基和杂环取代的四氢异喹啉及其用途
CN102595902B (zh) *	2009-05-12	2015-04-29	阿尔巴尼分子研究公司	7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途
US20140235667A1 (en)	2011-09-22	2014-08-21	Merck Sharp & Dohme Corp.	Imidazopyridyl compounds as aldosterone synthase inhibitors
WO2013043520A1 (en)	2011-09-22	2013-03-28	Merck Sharp & Dohme Corp.	Triazolopyridyl compounds as aldosterone synthase inhibitors
JP7399589B2 (ja) *	2018-09-12	2023-12-18	日本化薬株式会社	有害生物防除剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9226735D0 (en)	1992-12-22	1993-02-17	Ici Plc	Azole derivatives
US5356894A (en)	1990-05-29	1994-10-18	Rodney Peter W	Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
AU2639299A (en)	1998-02-24	1999-09-15	Kyowa Hakko Kogyo Co. Ltd.	Remedies/preventives for parkinson's disease
US6355653B1 (en)	1999-09-06	2002-03-12	Hoffmann-La Roche Inc.	Amino-triazolopyridine derivatives

2001
- 2001-11-30 US US09/998,323 patent/US6506772B1/en not_active Expired - Fee Related
- 2001-12-07 ES ES01991804T patent/ES2230387T3/es not_active Expired - Lifetime
- 2001-12-07 BR BR0116193-8A patent/BR0116193A/pt not_active Application Discontinuation
- 2001-12-07 KR KR1020037008004A patent/KR100540628B1/ko not_active Expired - Fee Related
- 2001-12-07 DK DK01991804T patent/DK1347974T3/da active
- 2001-12-07 MX MXPA03005334A patent/MXPA03005334A/es active IP Right Grant
- 2001-12-07 AT AT01991804T patent/ATE281456T1/de active
- 2001-12-07 JP JP2002549676A patent/JP4049672B2/ja not_active Expired - Fee Related
- 2001-12-07 PT PT01991804T patent/PT1347974E/pt unknown
- 2001-12-07 WO PCT/EP2001/014399 patent/WO2002048145A1/en not_active Ceased
- 2001-12-07 CN CNB018220304A patent/CN1221551C/zh not_active Expired - Fee Related
- 2001-12-07 AU AU3167402A patent/AU3167402A/xx active Pending
- 2001-12-07 AU AU2002231674A patent/AU2002231674B2/en not_active Ceased
- 2001-12-07 CA CA002437006A patent/CA2437006C/en not_active Expired - Fee Related
- 2001-12-07 EP EP01991804A patent/EP1347974B1/de not_active Expired - Lifetime
- 2001-12-07 DE DE60106974T patent/DE60106974T2/de not_active Expired - Lifetime
- 2001-12-12 PA PA20018534701A patent/PA8534701A1/es unknown
- 2001-12-12 AR ARP010105765A patent/AR031799A1/es unknown
- 2001-12-12 PE PE2001001245A patent/PE20020666A1/es not_active Application Discontinuation
- 2001-12-14 GT GT200100253A patent/GT200100253A/es unknown
- 2001-12-14 UY UY27074A patent/UY27074A1/es not_active Application Discontinuation
2003
- 2003-06-09 ZA ZA200304481A patent/ZA200304481B/en unknown

Also Published As

Publication number	Publication date
KR100540628B1 (ko)	2006-01-11
JP4049672B2 (ja)	2008-02-20
PT1347974E (pt)	2005-02-28
KR20030061446A (ko)	2003-07-18
AR031799A1 (es)	2003-10-01
MXPA03005334A (es)	2004-04-02
DK1347974T3 (da)	2005-03-14
BR0116193A (pt)	2003-09-23
ATE281456T1 (de)	2004-11-15
CN1221551C (zh)	2005-10-05
PA8534701A1 (es)	2002-08-26
ES2230387T3 (es)	2005-05-01
EP1347974A1 (de)	2003-10-01
UY27074A1 (es)	2002-07-31
AU3167402A (en)	2002-06-24
GT200100253A (es)	2002-07-31
ZA200304481B (en)	2004-09-09
CA2437006C (en)	2009-10-27
AU2002231674B2 (en)	2006-07-06
EP1347974B1 (de)	2004-11-03
CA2437006A1 (en)	2002-06-20
CN1486314A (zh)	2004-03-31
PE20020666A1 (es)	2002-07-27
WO2002048145A1 (en)	2002-06-20
US6506772B1 (en)	2003-01-14
DE60106974T2 (de)	2005-11-03
JP2004521096A (ja)	2004-07-15

Publication	Publication Date	Title
ATE253067T1 (de)	2003-11-15	Diazabicyloderivate als nikotin-acetylcholin- rezeptorliganden
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CY2011002I1 (el)	2012-01-25	N-πυρραζολικοι αγωνιστες του α2α υποδοχεα
ATE293618T1 (de)	2005-05-15	4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
DE60130463D1 (de)	2007-10-25	Pyrimidin-derivate
NO20024766L (no)	2002-11-28	Etylendiaminderivater
ATE360620T1 (de)	2007-05-15	Imidazolderivate
PT1303521E (pt)	2005-05-31	Derivados de tetra-hidro-heterocicloazepinil-pirimidina
ATE306265T1 (de)	2005-10-15	Benzothiazolderivate als adenosin-rezeptor- liganden
PL373953A1 (en)	2005-09-19	7-amino-benzothiazole derivatives as adenosine receptor ligands
DE60114852D1 (de)	2005-12-15	Chinazolin-derivate als alpha-1 adrenerge antagonisten
DE60137061D1 (de)	2009-01-29	Platin-verbindungen als antitumorwirkstoffe
ATE414056T1 (de)	2008-11-15	Substituierte c-cyclohexylmethylamin-derivative
AR028602A1 (es)	2003-05-14	Derivados de pirrol
DE60203820D1 (de)	2005-05-25	Pyridinderivate als nmda-rezeptorliganden
AR028282A1 (es)	2003-04-30	Derivados de aminofenil pirimidona
ATE281456T1 (de)	2004-11-15	Aminotriazolopyridinderivate als adenosinrezeptorliganden
DE60305058D1 (de)	2006-06-08	Imidazoquinoline derivate als adenosine a3 rezeptor liganden
HRP20040672A2 (en)	2005-08-31	Triazolo-quinolin derivatives useful as adenosine receptor ligands
ATE282021T1 (de)	2004-11-15	Substituierte aminomethyl-phenyl- cyclohexanderivate
DE60003072D1 (de)	2003-07-03	Thiazolidindion-derivate als antidiabetika
DE50103035D1 (de)	2004-09-02	Substituierte 1-aminobutan-3-ol-derivate
ATE338043T1 (de)	2006-09-15	5-methoxy-8-aryl- 1,2,4ötriazolo 1,5-aöpyridine derivative als adenosin-rezeptor antagonisten
PT1246791E (pt)	2005-03-31	Derivados de aminometilfenilciclo-hexanona
DE60012953D1 (de)	2004-09-16	3-amino-2-phenylpiperidinderivate als substanz p antagonisten

Legal Events

Date	Code	Title	Description
2005-12-08	8364	No opposition during term of opposition