PT1220693E - Formulacoes para libertacao de proteinas osteogenicas - Google Patents
Formulacoes para libertacao de proteinas osteogenicasInfo
- Publication number
- PT1220693E PT1220693E PT00972168T PT00972168T PT1220693E PT 1220693 E PT1220693 E PT 1220693E PT 00972168 T PT00972168 T PT 00972168T PT 00972168 T PT00972168 T PT 00972168T PT 1220693 E PT1220693 E PT 1220693E
- Authority
- PT
- Portugal
- Prior art keywords
- formulations
- osteogenic protein
- liberation
- osteogenic
- disclosed
- Prior art date
Links
- 230000002188 osteogenic effect Effects 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 108010010803 Gelatin Proteins 0.000 abstract 2
- 239000006260 foam Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 229920000159 gelatin Polymers 0.000 abstract 2
- 239000008273 gelatin Substances 0.000 abstract 2
- 235000019322 gelatine Nutrition 0.000 abstract 2
- 235000011852 gelatine desserts Nutrition 0.000 abstract 2
- 230000002439 hemostatic effect Effects 0.000 abstract 2
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 abstract 1
- 229940078499 tricalcium phosphate Drugs 0.000 abstract 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 abstract 1
- 235000019731 tricalcium phosphate Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Inorganic Chemistry (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15970399P | 1999-10-15 | 1999-10-15 | |
| US18573400P | 2000-02-29 | 2000-02-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1220693E true PT1220693E (pt) | 2005-02-28 |
Family
ID=26856202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00972168T PT1220693E (pt) | 1999-10-15 | 2000-10-13 | Formulacoes para libertacao de proteinas osteogenicas |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1220693B1 (pt) |
| JP (1) | JP2003512097A (pt) |
| AT (1) | ATE284230T1 (pt) |
| AU (1) | AU1086601A (pt) |
| DE (1) | DE60016614T2 (pt) |
| ES (1) | ES2233469T3 (pt) |
| PT (1) | PT1220693E (pt) |
| WO (1) | WO2001028603A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6949251B2 (en) | 2001-03-02 | 2005-09-27 | Stryker Corporation | Porous β-tricalcium phosphate granules for regeneration of bone tissue |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| EP1448246B2 (en) | 2001-11-19 | 2015-09-09 | Scil Technology GmbH | Method for producing a homogeneously coated device having osteoinductive and osteoconductive properties |
| AU2002367086B2 (en) | 2001-12-21 | 2008-08-21 | Ferrosan Medical Devices A/S | A hemostatic kit, a method of preparing a hemostatic agent and a method of promoting hemostasis |
| AU2003253049A1 (en) | 2002-09-10 | 2004-04-30 | Scil Technology Gmbh | Metal implant coated under reduced oxygen concentration with osteoinductive protein |
| US8440225B2 (en) | 2003-08-07 | 2013-05-14 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
| US7927626B2 (en) | 2003-08-07 | 2011-04-19 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
| US20060019868A1 (en) | 2004-01-30 | 2006-01-26 | Pendharkar Sanyog M | Hemostatic compositions and devices |
| CN1878565B (zh) * | 2003-09-12 | 2011-01-12 | 惠氏公司 | 用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂 |
| US8372419B2 (en) | 2004-03-10 | 2013-02-12 | Scil Technology Gmbh | Coated implants, their manufacturing and use thereof |
| FR2881651A1 (fr) * | 2005-02-09 | 2006-08-11 | Urodelia Sa | Nouveau produit pharmaceutique et procede de fabrication de ce produit pharmaceutique |
| US8642831B2 (en) | 2008-02-29 | 2014-02-04 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
| CA3048850A1 (en) | 2010-05-11 | 2011-11-17 | Howmedica Osteonics Corp. | Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods |
| EP2822474B1 (en) | 2012-03-06 | 2018-05-02 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
| EP2977066A3 (en) | 2012-06-12 | 2016-07-27 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
| WO2014202760A2 (en) | 2013-06-21 | 2014-12-24 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
| BR112016013322B1 (pt) | 2013-12-11 | 2020-07-21 | Ferrosan Medical Devices A/S | métodos para preparação de uma composição seca e para reconstituir uma composição seca, composição seca, uso de uma composição seca, e, kit |
| AU2015333206B2 (en) | 2014-10-13 | 2019-07-11 | Ferrosan Medical Devices A/S. | Dry composition for use in haemostasis and wound healing |
| EP3237041B1 (en) | 2014-12-24 | 2020-01-29 | Ferrosan Medical Devices A/S | Syringe for retaining and mixing first and second substances |
| CA2986981A1 (en) | 2015-07-03 | 2017-01-12 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
| EP3681950A4 (en) | 2017-09-12 | 2021-06-16 | Shilpa Medicare Limited | TRANEXAMIC ACID SPRAY FOR KNEE ARTHROPLASTICS |
| US10675330B2 (en) | 2018-03-21 | 2020-06-09 | Warsaw Orthopedic, Inc. | Injectable bone morphogenetic protein |
| EP3790600B1 (en) | 2018-05-09 | 2023-12-27 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
| US11324806B2 (en) | 2018-10-19 | 2022-05-10 | Warsaw Orthopedic, Inc. | Sustained delivery of a growth differentiation factor |
| CN113144277B (zh) * | 2021-04-13 | 2022-06-14 | 武汉理工大学 | 一种可注射流体明胶及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6432371A (en) * | 1987-07-29 | 1989-02-02 | Nec Corp | Inter-processor communicator system |
| DE69331096T2 (de) * | 1992-02-28 | 2002-08-14 | Cohesion Technologies, Inc. | Injektierbare, keramische verbindungen sowie verfahren zur deren herstellung und anwendung |
| ATE439849T1 (de) * | 1996-04-19 | 2009-09-15 | Osiris Therapeutics Inc | Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen |
| US20020076429A1 (en) * | 1998-01-28 | 2002-06-20 | John F. Wironen | Bone paste subjected to irradiative and thermal treatment |
| CN1094759C (zh) * | 1998-12-21 | 2002-11-27 | 冶金工业部钢铁研究总院 | 骨基质明胶载体的去活方法 |
-
2000
- 2000-10-13 DE DE60016614T patent/DE60016614T2/de not_active Expired - Fee Related
- 2000-10-13 JP JP2001531431A patent/JP2003512097A/ja not_active Withdrawn
- 2000-10-13 PT PT00972168T patent/PT1220693E/pt unknown
- 2000-10-13 EP EP00972168A patent/EP1220693B1/en not_active Expired - Lifetime
- 2000-10-13 ES ES00972168T patent/ES2233469T3/es not_active Expired - Lifetime
- 2000-10-13 WO PCT/US2000/028471 patent/WO2001028603A1/en not_active Ceased
- 2000-10-13 AT AT00972168T patent/ATE284230T1/de not_active IP Right Cessation
- 2000-10-13 AU AU10866/01A patent/AU1086601A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001028603A1 (en) | 2001-04-26 |
| JP2003512097A (ja) | 2003-04-02 |
| ES2233469T3 (es) | 2005-06-16 |
| EP1220693A1 (en) | 2002-07-10 |
| DE60016614T2 (de) | 2005-12-22 |
| AU1086601A (en) | 2001-04-30 |
| EP1220693B1 (en) | 2004-12-08 |
| ATE284230T1 (de) | 2004-12-15 |
| DE60016614D1 (de) | 2005-01-13 |
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