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PL4031552T3 - Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów - Google Patents

Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów

Info

Publication number
PL4031552T3
PL4031552T3 PL20781670.3T PL20781670T PL4031552T3 PL 4031552 T3 PL4031552 T3 PL 4031552T3 PL 20781670 T PL20781670 T PL 20781670T PL 4031552 T3 PL4031552 T3 PL 4031552T3
Authority
PL
Poland
Prior art keywords
pyridazin
azole
fused
derivatives
fused pyridazin
Prior art date
Application number
PL20781670.3T
Other languages
English (en)
Inventor
Holger Monenschein
Sean Murphy
Scott Olsen
Natasha O'ROURKE
Holly REICHARD
Melinda DAVIS
Betty Lam
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of PL4031552T3 publication Critical patent/PL4031552T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL20781670.3T 2019-09-16 2020-09-15 Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów PL4031552T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962901052P 2019-09-16 2019-09-16
PCT/US2020/050823 WO2021055326A1 (en) 2019-09-16 2020-09-15 Azole-fused pyridazin-3(2h)-one derivatives

Publications (1)

Publication Number Publication Date
PL4031552T3 true PL4031552T3 (pl) 2025-03-17

Family

ID=72670806

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20781670.3T PL4031552T3 (pl) 2019-09-16 2020-09-15 Pochodne azolowo-skondensowanych pirydazyn-3(2h)-onów

Country Status (25)

Country Link
US (1) US12370192B2 (pl)
EP (1) EP4031552B1 (pl)
JP (1) JP7566888B2 (pl)
KR (1) KR20220063228A (pl)
CN (1) CN114728975A (pl)
AR (1) AR119971A1 (pl)
AU (1) AU2020348675B2 (pl)
BR (1) BR112022004819A2 (pl)
CA (1) CA3150508A1 (pl)
CO (1) CO2022004684A2 (pl)
CR (1) CR20220160A (pl)
DO (1) DOP2022000057A (pl)
EC (1) ECSP22020159A (pl)
ES (1) ES2997267T3 (pl)
HR (1) HRP20250088T1 (pl)
HU (1) HUE069908T2 (pl)
IL (1) IL291181B2 (pl)
JO (1) JOP20220063A1 (pl)
MX (1) MX2022003177A (pl)
PE (1) PE20221341A1 (pl)
PH (1) PH12022550597A1 (pl)
PL (1) PL4031552T3 (pl)
RS (1) RS66463B1 (pl)
TW (1) TWI873185B (pl)
WO (1) WO2021055326A1 (pl)

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JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
PH12022550597A1 (en) 2019-09-16 2024-03-04 Takeda Pharmaceuticals Co Azole-fused pyridazin-3(2h)-one derivatives
CN114149371B (zh) * 2021-11-26 2023-08-22 首都医科大学 四取代吡唑类化合物及其应用
WO2023165262A1 (zh) * 2022-03-01 2023-09-07 上海科技大学 噻吩并含氮杂环类化合物、含其的药物组合物、其制备方法及其应用
WO2023165263A1 (zh) * 2022-03-01 2023-09-07 上海科技大学 吡咯并三嗪酮类化合物、含其的药物组合物、其制备方法及其应用
IT202200024948A1 (it) * 2022-12-05 2024-06-05 Angelini Pharma S P A Composti attivatori dei canali potassio KV7.2/KV7.3
CN116063179A (zh) * 2023-02-20 2023-05-05 南京杰运医药科技有限公司 一种4-甲氧基乙酰乙酸甲酯的合成方法
WO2025119351A1 (zh) * 2023-12-08 2025-06-12 深圳湾实验室 Gpr139激动剂
WO2025124544A1 (zh) * 2023-12-14 2025-06-19 华润医药研究院（深圳）有限公司 3,4-二氢-2H-苯并[b][1,4]二氧杂环庚烷类化合物及其制备方法和医药用途
CN120424068A (zh) * 2024-02-02 2025-08-05 上海科技大学 稠杂环类化合物与其制备方法、药物组合物及应用

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Also Published As

Publication number Publication date
MX2022003177A (es) 2022-04-06
RS66463B1 (sr) 2025-02-28
IL291181A (en) 2022-05-01
IL291181B2 (en) 2025-09-01
CA3150508A1 (en) 2021-03-25
ES2997267T3 (en) 2025-02-14
IL291181B1 (en) 2025-05-01
KR20220063228A (ko) 2022-05-17
TWI873185B (zh) 2025-02-21
JOP20220063A1 (ar) 2023-01-30
CN114728975A (zh) 2022-07-08
JP2022548602A (ja) 2022-11-21
CR20220160A (es) 2022-06-16
AU2020348675A1 (en) 2022-04-14
AU2020348675B2 (en) 2025-11-20
HUE069908T2 (hu) 2025-04-28
PE20221341A1 (es) 2022-09-13
US12370192B2 (en) 2025-07-29
CO2022004684A2 (es) 2022-07-08
US20230028114A1 (en) 2023-01-26
BR112022004819A2 (pt) 2022-06-07
JP7566888B2 (ja) 2024-10-15
PH12022550597A1 (en) 2024-03-04
TW202124386A (zh) 2021-07-01
ECSP22020159A (es) 2022-05-31
EP4031552B1 (en) 2024-11-06
EP4031552C0 (en) 2024-11-06
HRP20250088T1 (hr) 2025-03-28
EP4031552A1 (en) 2022-07-27
DOP2022000057A (es) 2022-06-30
AR119971A1 (es) 2022-01-26
WO2021055326A1 (en) 2021-03-25

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