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PL357603A1 - Podstawione pirole - Google Patents

Podstawione pirole

Info

Publication number
PL357603A1
PL357603A1 PL00357603A PL35760300A PL357603A1 PL 357603 A1 PL357603 A1 PL 357603A1 PL 00357603 A PL00357603 A PL 00357603A PL 35760300 A PL35760300 A PL 35760300A PL 357603 A1 PL357603 A1 PL 357603A1
Authority
PL
Poland
Prior art keywords
substituted pyrroles
pyrroles
substituted
Prior art date
Application number
PL00357603A
Other languages
English (en)
Inventor
Nader Fotouhi
Norman Kong
Allen John Lovey
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of PL357603A1 publication Critical patent/PL357603A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PL00357603A 1999-12-22 2000-12-21 Podstawione pirole PL357603A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17155799P 1999-12-22 1999-12-22
PCT/EP2000/013026 WO2001046178A2 (en) 1999-12-22 2000-12-21 Substituierte bisindolymaleimide

Publications (1)

Publication Number Publication Date
PL357603A1 true PL357603A1 (pl) 2004-07-26

Family

ID=22624198

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00357603A PL357603A1 (pl) 1999-12-22 2000-12-21 Podstawione pirole

Country Status (27)

Country Link
US (1) US6281356B1 (pl)
EP (1) EP1242409A2 (pl)
JP (1) JP2003518112A (pl)
KR (1) KR100508741B1 (pl)
CN (1) CN1193027C (pl)
AR (1) AR027035A1 (pl)
AU (1) AU782920B2 (pl)
BR (1) BR0016516A (pl)
CA (1) CA2394852A1 (pl)
CO (1) CO5090902A1 (pl)
CZ (1) CZ20022492A3 (pl)
HR (1) HRP20020536A2 (pl)
HU (1) HUP0204572A3 (pl)
IL (1) IL150200A0 (pl)
JO (1) JO2199B1 (pl)
MA (1) MA26860A1 (pl)
MX (1) MXPA02006162A (pl)
MY (1) MY133682A (pl)
NO (1) NO20022927D0 (pl)
NZ (1) NZ519359A (pl)
PE (1) PE20011098A1 (pl)
PL (1) PL357603A1 (pl)
RU (1) RU2261862C2 (pl)
UY (1) UY26498A1 (pl)
WO (1) WO2001046178A2 (pl)
YU (1) YU46302A (pl)
ZA (1) ZA200204313B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030139373A1 (en) * 2001-11-20 2003-07-24 Breimer Lars Holger Method for cancer therapy
AR039209A1 (es) 2002-04-03 2005-02-09 Novartis Ag Derivados de indolilmaleimida
GB0303319D0 (en) 2003-02-13 2003-03-19 Novartis Ag Organic compounds
RU2441000C2 (ru) * 2009-11-27 2012-01-27 Общество с ограниченной ответственностью "Молекулярные Технологии" 4-(1-(4-(4-метоксифенилтио)-2,5-диоксо-2,5-дигидро-1н-пирро-3-ил)-1н-индол-3-ил)бутилкарбамимидотиоат и способ его применения
RU2680100C9 (ru) 2013-03-15 2019-04-18 Плексксикон Инк. Гетероциклические соединения и их применения
US20140303121A1 (en) 2013-03-15 2014-10-09 Plexxikon Inc. Heterocyclic compounds and uses thereof
EP3272745B1 (en) * 2016-07-21 2019-06-26 Instytut Farmakologii Polskiej Akademii Nauk Imidazolyl-substituted indole derivatives binding 5-ht7 serotonin receptor and pharmaceutical compositions thereof
US10717735B2 (en) 2017-10-13 2020-07-21 Plexxikon Inc. Solid forms of a compound for modulating kinases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ280738B6 (cs) 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
DE3942991A1 (de) * 1989-12-27 1991-07-04 Goedecke Ag Maleinimid-derivate und deren verwendung als arzneimittel
US5380746A (en) 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
CA2015996C (en) * 1989-05-05 2001-08-28 Hartmut Osswald Bis-(1h-indol-3-yl)-maleinimide derivatives and their use as pharmaceuticals
CA2046801C (en) * 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
WO1993018765A1 (en) 1992-03-20 1993-09-30 The Wellcome Foundation Limited Indole derivatives with antiviral activity
DE69323183T2 (de) * 1992-03-20 1999-05-27 The Wellcome Foundation Ltd., Greenford Weitere indolderivate mit antiviraler wirkung
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
PE91698A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
PE91598A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
PE91498A1 (es) 1996-07-29 1998-12-22 Hoffmann La Roche Pirroles sustituidos
IL138247A (en) * 1998-03-17 2005-08-31 Hoffmann La Roche Substituted bisindolymaleimides for the inhibition of cell proliferation and pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
MXPA02006162A (es) 2002-12-05
CN1193027C (zh) 2005-03-16
US6281356B1 (en) 2001-08-28
AR027035A1 (es) 2003-03-12
IL150200A0 (en) 2002-12-01
KR20020062365A (ko) 2002-07-25
WO2001046178A3 (en) 2001-12-06
JP2003518112A (ja) 2003-06-03
AU3726701A (en) 2001-07-03
RU2261862C2 (ru) 2005-10-10
WO2001046178A2 (en) 2001-06-28
HK1054382A1 (en) 2003-11-28
HUP0204572A3 (en) 2004-07-28
EP1242409A2 (en) 2002-09-25
YU46302A (sh) 2005-06-10
HUP0204572A2 (en) 2003-05-28
MY133682A (en) 2007-11-30
CO5090902A1 (es) 2001-10-30
NO20022927L (no) 2002-06-18
UY26498A1 (es) 2001-06-29
JO2199B1 (en) 2003-12-23
BR0016516A (pt) 2002-09-17
RU2002119557A (ru) 2004-01-10
CN1411457A (zh) 2003-04-16
ZA200204313B (en) 2003-08-29
HRP20020536A2 (en) 2004-08-31
AU782920B2 (en) 2005-09-08
CA2394852A1 (en) 2001-06-28
PE20011098A1 (es) 2001-10-26
MA26860A1 (fr) 2004-12-20
NO20022927D0 (no) 2002-06-18
NZ519359A (en) 2004-04-30
KR100508741B1 (ko) 2005-08-17
CZ20022492A3 (cs) 2003-02-12

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)