[go: up one dir, main page]

PL2545777T3 - Zastosowanie kompozycji izoksazoliny jako środka przeciwpasożytniczego - Google Patents

Zastosowanie kompozycji izoksazoliny jako środka przeciwpasożytniczego

Info

Publication number
PL2545777T3
PL2545777T3 PL12188400T PL12188400T PL2545777T3 PL 2545777 T3 PL2545777 T3 PL 2545777T3 PL 12188400 T PL12188400 T PL 12188400T PL 12188400 T PL12188400 T PL 12188400T PL 2545777 T3 PL2545777 T3 PL 2545777T3
Authority
PL
Poland
Prior art keywords
parasitic agent
isoxazoline composition
isoxazoline
composition
parasitic
Prior art date
Application number
PL12188400T
Other languages
English (en)
Other versions
PL2545777T5 (pl
Inventor
Heike Williams
Anja Regina Heckeroth
Jürgen Lutz
Christina Mertens
Hartmut Zoller
Takeshi Mita
Original Assignee
Intervet International B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40152741&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2545777(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intervet International B.V. filed Critical Intervet International B.V.
Publication of PL2545777T3 publication Critical patent/PL2545777T3/pl
Publication of PL2545777T5 publication Critical patent/PL2545777T5/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PL12188400.1T 2007-08-17 2008-08-15 Zastosowanie kompozycji izoksazoliny jako środka przeciwpasożytniczego PL2545777T5 (pl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US95644807P 2007-08-17 2007-08-17
EP07016152 2007-08-17
EP07150309 2007-12-21
US8044408P 2008-07-14 2008-07-14
EP08803041.6A EP2190289B1 (en) 2007-08-17 2008-08-15 Isoxazoline compositions and their use as antiparasitics
PCT/EP2008/060732 WO2009024541A2 (en) 2007-08-17 2008-08-15 Isoxazoline compositions and their use as antiparasitics
EP12188400.1A EP2545777B2 (en) 2007-08-17 2008-08-15 Use of an isoxazoline composition as antiparasitic

Publications (2)

Publication Number Publication Date
PL2545777T3 true PL2545777T3 (pl) 2020-06-15
PL2545777T5 PL2545777T5 (pl) 2023-03-27

Family

ID=40152741

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12188400.1T PL2545777T5 (pl) 2007-08-17 2008-08-15 Zastosowanie kompozycji izoksazoliny jako środka przeciwpasożytniczego
PL08803041T PL2190289T3 (pl) 2007-08-17 2008-08-15 Kompozycje izoksazoliny oraz ich zastosowanie jako środków przeciwko pasożytom

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL08803041T PL2190289T3 (pl) 2007-08-17 2008-08-15 Kompozycje izoksazoliny oraz ich zastosowanie jako środków przeciwko pasożytom

Country Status (19)

Country Link
US (6) US20110059988A1 (pl)
EP (3) EP3473101B1 (pl)
JP (4) JP5411135B2 (pl)
KR (3) KR101792547B1 (pl)
CN (2) CN101778566A (pl)
AU (2) AU2008290581C1 (pl)
BR (2) BRPI0815227B1 (pl)
CA (1) CA2694919C (pl)
DK (2) DK2190289T3 (pl)
ES (2) ES2417157T3 (pl)
MX (2) MX351346B (pl)
NO (1) NO2016018I1 (pl)
NZ (2) NZ583045A (pl)
PL (2) PL2545777T5 (pl)
PT (1) PT2190289E (pl)
RU (3) RU2481837C2 (pl)
TW (1) TWI556741B (pl)
WO (1) WO2009024541A2 (pl)
ZA (2) ZA201203080B (pl)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
EP2151437A4 (en) * 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
BRPI0809770B8 (pt) 2007-06-13 2022-12-06 Du Pont Composto e composição para controlar uma praga de invertebrados
DK2957284T3 (en) * 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI583664B (zh) * 2008-04-09 2017-05-21 杜邦股份有限公司 羰基化合物及其製備方法
KR101680912B1 (ko) 2008-07-09 2016-11-29 바스프 에스이 이속사졸린 화합물 ⅰ을 포함하는 살충 활성 혼합물
KR101963426B1 (ko) 2008-07-09 2019-03-28 닛산 가가쿠 가부시키가이샤 이속사졸린 치환 안식향산 아미드 화합물의 제조 방법
EP2331536B1 (en) 2008-08-22 2013-08-21 Syngenta Participations AG Insecticidal compounds
EP2331515B1 (en) 2008-08-22 2013-07-10 Syngenta Participations AG Insceticidal compounds
AU2009289711A1 (en) 2008-09-04 2010-03-11 Syngenta Limited Insecticidal compounds
AR074024A1 (es) 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
KR101660068B1 (ko) 2008-11-19 2016-09-26 메리얼 인코포레이티드 기생충 감염 치료를 위한 1-아릴피라졸 단독 또는 포름아미딘과의 조합을 포함하는 조성물
TWI457347B (zh) 2008-12-04 2014-10-21 Merial Ltd 二聚合的阿佛菌素（ａｖｅｒｍｅｃｔｉｎ）及密倍脈心（ｍｉｌｂｅｍｙｃｉｎ）衍生物
US8853410B2 (en) 2009-04-30 2014-10-07 Basf Se Process for preparing substituted isoxazoline compounds and their precursors
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
RS58691B1 (sr) 2009-12-17 2019-06-28 Merial Inc Antiparazitske kompozicije dihidroazola
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
MX2012013758A (es) 2010-05-27 2013-01-24 Du Pont Forma cristalina de 4-[5-[3-cloro-5-trifluorometil)fenil]-4,5-dihi dro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoro etil)amino]etil]-1-naftalenocarboxamida.
TW201211057A (en) * 2010-06-11 2012-03-16 Syngenta Participations Ag Process for the preparation of dihydropyrrole derivatives
US9085541B2 (en) 2010-06-23 2015-07-21 Basf Se Process for producing imine compounds for combating invertebrate pests
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
CN103282345A (zh) 2010-11-03 2013-09-04 巴斯夫欧洲公司 制备取代的异噁唑啉化合物及其前体4-氯-、4-溴-或4-碘苯甲醛肟的方法
JP2014015397A (ja) * 2010-11-04 2014-01-30 Nippon Soda Co Ltd 動物用外部寄生虫防除剤
DE102010063691A1 (de) 2010-12-21 2012-06-21 Bayer Animal Health Gmbh Ektoparasitizide Wirkstoffkombinationen
RU2602189C2 (ru) * 2010-12-27 2016-11-10 Интервет Интернэшнл Б.В. Изоксазолиновый состав, содержащий гликофурол для наружного и местного применения
US9173870B2 (en) * 2010-12-27 2015-11-03 Intervet Inc. Topical localized isoxazoline formulation
KR102193090B1 (ko) * 2010-12-27 2020-12-21 인터벳 인터내셔널 비.브이. 국소 적용 이속사졸린 제제
WO2012155352A1 (en) 2011-05-19 2012-11-22 Eli Lilly And Company Dihydroisoxazole compounds, parasiticidal uses and formulations thereof
BR112013033568B1 (pt) 2011-06-27 2020-11-24 Merial, Inc Compostos eter amidopiridil e composiqoes, e seu uso contra parasitas
PH12018501647A1 (en) 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
AR088669A1 (es) 2011-11-21 2014-06-25 Lilly Co Eli Derivados de dihidrodibenzo[c][1,2]oxaborol y dihidroisoxazol utiles para el control de ectoparasitos
BR112014012942A2 (pt) * 2011-11-29 2017-06-13 Novartis Ag uso de derivados de aril para controle de ectoparasitas
PL2785719T3 (pl) 2011-12-02 2018-03-30 Merial, Inc. Długodziałające wstrzykiwalne postaci moksydektyny i nowe postaci krystaliczne moksydektyny
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014024832B1 (pt) 2012-04-04 2022-05-31 Intervet International B.V. Método para a preparação de uma composição farmacêutica veterinária mastigável macia, composição farmacêutica, e, uso da composição
BR112014026184B1 (pt) 2012-04-20 2019-04-24 Merial, Inc. Composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
AU2013245478A1 (en) * 2012-11-01 2014-05-15 Sumitomo Chemical Company, Limited Method for administering agent for controlling ectoparasite to dog
US9532946B2 (en) * 2012-11-20 2017-01-03 Intervet Inc. Manufacturing of semi-plastic pharmaceutical dosage units
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
ES2656012T3 (es) 2013-02-06 2018-02-22 Bayer Cropscience Aktiengesellschaft Derivados de pirazol sustituidos con halógeno como pesticidas
EP2968569A4 (en) 2013-03-15 2016-11-02 Argenta Mfg Ltd COUGAR FORMULATION
WO2015195928A1 (en) 2014-06-19 2015-12-23 Attillaps Holdings Acetylcholinesterase inhibitors for treatment of dermatological conditions
EP3030084A4 (en) 2013-07-29 2016-07-27 Attillaps Holdings Organophosphates for the treatment of skin disorders
US11446241B2 (en) 2013-07-29 2022-09-20 Attillaps Holdings Inc. Treatment of ophthalmological conditions with acetylcholinesterase inhibitors
US9371293B2 (en) * 2013-10-25 2016-06-21 Sumitomo Chemical Company, Limited Isoxazoline compound composition
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
ES2742815T3 (es) 2013-12-10 2020-02-17 Intervet Int Bv Uso antiparasitario de compuestos de isoxazolina
HUE063842T2 (hu) 2013-12-20 2024-02-28 Intervet Int Bv Izoxazolin vegyületek felhasználása baromfiban
WO2015091898A1 (en) * 2013-12-20 2015-06-25 Intervet International B.V. Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals
KR20160104065A (ko) 2014-01-03 2016-09-02 바이엘 애니멀 헬스 게엠베하 농약으로서의 신규 피라졸릴헤테로아릴아미드
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
RU2017104717A (ru) 2014-07-15 2018-08-15 Байер Энимэл Хельс ГмбХ Арилтриазолилпиридины в качестве средств для борьбы с вредителями
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
PL3236960T3 (pl) * 2014-12-22 2025-07-07 Intervet International B.V. Fluralaner do zastosowania w leczeniu demodekozy
UY36570A (es) * 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
BR112017021073A2 (pt) 2015-04-08 2018-07-03 Merial Inc composições injetáveis de liberação prolongada compreendendo um agente ativo de isoxazolina, seus métodos e usos
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
BR112017027855B1 (pt) * 2015-06-23 2022-11-16 Intervet International B.V. Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
PL3978483T3 (pl) 2016-04-06 2025-03-24 Boehringer Ingelheim Vetmedica Gmbh Krystaliczny solwat toluenowy (S)-afoksolaneru
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
CN107535503A (zh) * 2017-07-21 2018-01-05 陕西康禾立丰生物科技药业有限公司 一种含有氟噁唑酰胺和新烟碱类的杀虫组合物
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
CN107593723A (zh) * 2017-09-29 2018-01-19 北京科发伟业农药技术中心 一种含fluxametamide的组合物
AU2018363686B2 (en) 2017-11-07 2023-11-23 Intervet International B.V. Process for preparing large size isoxazoline particles
PE20201150A1 (es) 2017-11-07 2020-10-26 Intervet Int Bv Composiciones farmaceuticas inyectables de isoxazolina y usos de las mismas
US11648238B2 (en) 2017-12-12 2023-05-16 Intervet Inc. Implantable isoxazoline pharmaceutical compositions and uses thereof
KR20250065422A (ko) 2017-12-15 2025-05-12 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
AU2020208145B2 (en) 2019-01-16 2023-02-02 Boehringer Ingelheim Vetmedica Gmbh Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
US20220202835A1 (en) 2019-03-01 2022-06-30 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
EP3946325A4 (en) * 2019-04-04 2022-12-21 Tarsus Pharmaceuticals, Inc. SYSTEMIC ISOXAZOLINE PARASITICIDES FOR THE TREATMENT OR PROPHYLAXIS OF VECTOR-TRANSMITTED AND VIRAL DISEASES
MX2021013429A (es) 2019-05-03 2021-12-10 Intervet Int Bv Composiciones farmaceuticas inyectables y usos de las mismas.
CN112174905B (zh) * 2019-07-01 2023-10-20 沈阳化工大学 一种异噁唑啉类化合物及其制备方法和应用
BR112022000982A2 (pt) 2019-07-22 2022-03-08 Intervet Int Bv Forma de dosagem veterinária mastigável macia
AU2020409532A1 (en) 2019-12-16 2022-05-12 Intervet International B.V. Composition for lice control
BR112022011046A2 (pt) 2019-12-16 2022-08-23 Intervet Int Bv Composição para controle de piolhos em avinos
WO2021122515A1 (en) 2019-12-16 2021-06-24 Intervet International B.V. Parasite control in ruminants
MX2022014493A (es) 2020-05-20 2022-12-13 Intervet Int Bv Composiciones farmaceuticas inyectables y usos de las mismas.
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
CN111657292A (zh) * 2020-06-03 2020-09-15 浙江中山化工集团股份有限公司 一种含有氟噁唑酰胺和高效氯氰菊酯的杀虫组合物
JP7724845B2 (ja) 2020-07-24 2025-08-18 エランコ・ユーエス・インコーポレイテッド イソオキサゾリン化合物及びその中間体を作製するための方法
CN111909143B (zh) * 2020-07-30 2021-10-29 山东省联合农药工业有限公司 一种异噁唑啉取代的苯甲酰胺类衍生物及其制备方法与用途
WO2022133233A2 (en) 2020-12-17 2022-06-23 Idexx Laboratories, Inc. Rocky mountain spotted fever detection and treatment
EP4263559A1 (en) 2020-12-18 2023-10-25 Boehringer Ingelheim Animal Health USA Inc. Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
EP4284175A1 (en) 2021-01-27 2023-12-06 Intervet International B.V. Cyclopropylamide compounds against parasites in fish
CN117412673A (zh) * 2021-03-11 2024-01-16 碗中动物健康公司 犬科动物口服饲料和在犬科动物中控制蚤侵袭的方法
CA3211576A1 (en) * 2021-03-11 2022-09-15 In The Bowl Animal Health, Inc. Oral canine feed and methods for controlling tick infestations in a canine
CA3217124A1 (en) * 2021-04-30 2022-11-03 John O'halloran Use of isoxazoline for protection against parasitic pests in fish
AU2022296860A1 (en) 2021-06-25 2023-12-14 Intervet International B.V. Palatable veterinary compositions
CN113563322B (zh) * 2021-07-26 2023-07-07 海利尔药业集团股份有限公司 一种取代的苯甲酰胺类异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途
KR102660238B1 (ko) * 2021-12-20 2024-04-25 주식회사경농 다이하이드로아이소옥사졸 유도체 화합물 및 이를 포함하는 살충제 조성물
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
CN117122571A (zh) * 2022-05-20 2023-11-28 天津瑞普生物技术股份有限公司 一种抗寄生虫感染的口服药物制剂及其制备方法和应用
WO2023221868A1 (zh) * 2022-05-20 2023-11-23 天津瑞普生物技术股份有限公司 一种异噁唑啉类化合物的衍生物及其应用
KR20240002746A (ko) * 2022-06-30 2024-01-08 주식회사경농 이속사졸린 유도체 화합물 및 이를 포함하는 살충제 조성물
CN115785017B (zh) * 2022-12-06 2023-12-08 海利尔药业集团股份有限公司 一种取代的苯酰胺异噁唑啉衍生物或其作为农药可接受的盐、组合物及其用途
UA130006C2 (uk) 2023-08-07 2025-10-08 Юрій Юрійович Синиця Водорозчинний комплекс афоксоланера, спосіб його отримання та ветеринарні протипаразитарні препарати, що його містять
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
CN120040365A (zh) * 2023-11-24 2025-05-27 山东康乔生物科技有限公司 异噁唑啉类化合物及其制备方法和应用
WO2025191150A2 (en) 2024-03-15 2025-09-18 Krka, D.D., Novo Mesto Stable isoxazoline formulation for topical application to the skin
WO2025218782A1 (zh) * 2024-04-19 2025-10-23 齐鲁动物保健品有限公司 异噁唑啉类化合物及其用途
CN118614509B (zh) * 2024-05-31 2025-08-08 海利尔药业集团股份有限公司 一种含有生物源杀虫剂的农药组合物及其应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753377B1 (fr) 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them
EP0539588A1 (en) 1990-07-05 1993-05-05 Nippon Soda Co., Ltd. Amine derivative
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
DE69637964D1 (de) 1995-03-20 2009-08-20 Merck & Co Inc Derivaten von Nodulisporen Säure
US5595991A (en) 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
FR2750861B1 (fr) 1996-07-11 1998-12-24 Rhone Merieux Procedes d'elimination des parasites, et notamment des ectoparasites de vertebres, notamment de mammiferes et compositions pour la mise en oeuvre de ce procede
US5834260A (en) 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
US20050192319A1 (en) 1996-09-19 2005-09-01 Albert Boeckh Spot-on formulations for combating parasites
FR2761232B1 (fr) 1997-03-26 2000-03-10 Rhone Merieux Procede et moyens d'eradication des puces dans les locaux habites par les petits mammiferes
RU2129430C1 (ru) * 1998-03-17 1999-04-27 Общество С Ограниченной Ответственностью "Вик - Здоровье Животных" Препарат для борьбы с экто- и эндопаразитами животных "сантомектин"
US6265384B1 (en) * 1999-01-26 2001-07-24 Dale L. Pearlman Methods and kits for removing, treating, or preventing lice with driable pediculostatic agents
GB9916052D0 (en) 1999-07-08 1999-09-08 Pfizer Ltd Anthelmintic compositions
RU2149007C1 (ru) * 1999-09-28 2000-05-20 Закрытое акционерное общество "Агроветсервис" Антипаразитарная, антимикробная противовоспалительная мазь пролонгированного действия
US7129271B2 (en) * 2000-12-08 2006-10-31 The United States Of America As Represented By The Department Of Health And Human Services Compounds for pest control and methods for their use
EP1671941A4 (en) 2003-09-30 2007-12-12 Nissan Chemical Ind Ltd SUBSTITUTED BENZANILIDE COMPOUND AND PEST CONTROL AGENT
GB0402677D0 (en) 2003-11-06 2004-03-10 Novartis Ag Organic compounds
BRPI0418328A (pt) 2003-12-31 2007-05-02 Schering Plough Ltd controle de parasitas em animais pelo uso de derivados de imidazo [1,2-b]piridazina
WO2005066119A2 (en) 2003-12-31 2005-07-21 Schering-Plough Ltd. Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoropropanols and preparation thereof
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
ATE406348T1 (de) 2004-09-23 2008-09-15 Schering Plough Ltd Bekämpfung von parasiten in tieren durch verwendung neuer trifluormethansulfonanilidoximetherderivate
DK1812385T3 (da) 2004-11-09 2012-10-15 Novartis Ag Fremgangsmåde til fremstilling af enantiomere af amidoacetonitrilforbindelser ud fra deres racemater
MX2007006072A (es) 2004-11-19 2007-07-11 Schering Plough Ltd Control de parasitos en animales mediante el uso de derivados del parasiticida 2-fenil-3-(1h-pirrol-2-il)acrilonitrilo.
DE602004015333D1 (de) 2004-12-15 2008-09-04 Matsushita Electric Industrial Co Ltd Unterstützung für garantierten Bitratenverkehr für Uplink Übertragungen
MX2007015729A (es) 2005-06-09 2008-02-21 Schering Plough Ltd Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
US20070010465A1 (en) * 2005-07-06 2007-01-11 Branimir Sikic Zosuquidar, daunorubicin, and cytarabine for the treatment of cancer
JP4479917B2 (ja) 2005-09-02 2010-06-09 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
CA2621228C (en) 2005-09-02 2014-05-27 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and pesticide
AR057219A1 (es) 2005-12-06 2007-11-21 Wyeth Corp COMPOSICION, METODO PARA EL TRATAMIENTO Y CONTROL DE UNA INFECCION ECTOPARASíTICA O INFESTACION Y PROCESO PARA LA PREPARACION DE LA COMPOSICION.
US20090143410A1 (en) 2005-12-14 2009-06-04 Kanu Maganbhai Patel Isoxazolines for Controlling Invertebrate Pests
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
DE102006015470A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
UA110598C2 (uk) 2006-11-10 2016-01-25 Басф Се Спосіб одержання кристалічної модифікації фіпронілу
JP2008133242A (ja) 2006-11-29 2008-06-12 Nissan Chem Ind Ltd 置換フェニルリチウム化合物の製造方法
DK2957284T3 (en) * 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
TWI556741B (zh) * 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
US8044409B2 (en) 2008-08-11 2011-10-25 Taiwan Semiconductor Manufacturing Company, Ltd. III-nitride based semiconductor structure with multiple conductive tunneling layer

Also Published As

Publication number Publication date
KR101792547B1 (ko) 2017-11-02
US20240239759A1 (en) 2024-07-18
JP6251308B2 (ja) 2017-12-20
ES2417157T3 (es) 2013-08-06
ES2785104T5 (es) 2023-04-28
BR122020005235B1 (pt) 2023-11-14
KR20160032278A (ko) 2016-03-23
JP6458095B2 (ja) 2019-01-23
ZA202409111B (en) 2025-08-27
JP2014097982A (ja) 2014-05-29
AU2013207639B2 (en) 2016-05-12
RU2481837C2 (ru) 2013-05-20
MX351346B (es) 2017-10-11
TW200924649A (en) 2009-06-16
US20150111936A1 (en) 2015-04-23
NO2016018I1 (no) 2016-10-05
CN101778566A (zh) 2010-07-14
DK2190289T3 (da) 2013-07-29
US20110059988A1 (en) 2011-03-10
AU2008290581A1 (en) 2009-02-26
BRPI0815227B1 (pt) 2021-02-23
KR101725320B1 (ko) 2017-04-10
RU2602308C2 (ru) 2016-11-20
PL2545777T5 (pl) 2023-03-27
EP2190289B1 (en) 2013-05-01
JP6014006B2 (ja) 2016-10-25
EP3473101B1 (en) 2021-05-12
AU2008290581B2 (en) 2013-07-25
KR20100057066A (ko) 2010-05-28
JP5411135B2 (ja) 2014-02-12
US20160332975A1 (en) 2016-11-17
CA2694919A1 (en) 2009-02-26
CA2694919C (en) 2017-10-17
KR20170041281A (ko) 2017-04-14
US20180155301A1 (en) 2018-06-07
AU2008290581C1 (en) 2019-07-11
EP2545777B2 (en) 2023-01-18
RU2013107094A (ru) 2014-08-27
RU2016133168A (ru) 2018-02-16
TWI556741B (zh) 2016-11-11
CN103705509A (zh) 2014-04-09
HK1143037A1 (en) 2010-12-24
DK3473101T3 (da) 2021-07-12
RU2715051C2 (ru) 2020-02-25
PL2190289T3 (pl) 2013-09-30
NZ583045A (en) 2012-06-29
EP2545777B1 (en) 2020-03-11
EP3473101A1 (en) 2019-04-24
MX2010001907A (es) 2010-04-27
WO2009024541A3 (en) 2010-04-01
BRPI0815227A2 (pt) 2019-08-06
ZA201203080B (en) 2012-12-27
JP2016147888A (ja) 2016-08-18
EP2545777A1 (en) 2013-01-16
RU2010109901A (ru) 2011-09-27
JP2010536733A (ja) 2010-12-02
US20210061775A1 (en) 2021-03-04
PT2190289E (pt) 2013-08-22
RU2016133168A3 (pl) 2019-12-12
EP2190289A2 (en) 2010-06-02
WO2009024541A2 (en) 2009-02-26
NZ599797A (en) 2013-08-30
ES2785104T3 (es) 2020-10-05
JP2017222692A (ja) 2017-12-21

Similar Documents

Publication Publication Date Title
PL2545777T3 (pl) Zastosowanie kompozycji izoksazoliny jako środka przeciwpasożytniczego
PL3354276T3 (pl) Kompozycje do leczenia zapalenia przewodu pokarmowego
CR10847A (es) Compuesto heteromonociclico y uso del mismo
BRPI0716325A2 (pt) Composição antimicrobianas
BRPI0810362A2 (pt) Compostos de morfolinila deuterados
DK2234600T3 (da) Antistofformulering
EP2037789A4 (en) BLENDER
EP3329912C0 (en) LIQUID COMPOSITION
BRPI0813627A2 (pt) Peptídio antimicrobiano, composições e métodos de uso
BR112012004335A2 (pt) composto, composição farmacêutica, e, uso do composto.
ATE528048T1 (de) Schweisshemmende/desodorierende zusammensetzung
FR2929661B1 (fr) Retenue axiale d&#39;aubes de compresseur.
DK2178568T3 (da) Kontrastmidler
BRPI0813341A2 (pt) &#34; uso de compostos, composições curáveis, e, uso de composições curáveis &#34;.
EP2043136A4 (en) FILMING COMPOSITION
FR2899479B1 (fr) Composition cicatrisante
BRPI0810557A2 (pt) composição
BRPI0811274A2 (pt) Composição
PL2205720T3 (pl) Kompozycja do leczenia stwardnienia rozsianego
EP2197828A4 (en) FULLERENE MULTI-ADDUCT COMPOSITIONS
BRPI0911772A2 (pt) composto, composição farmacêutica, e, uso do composto.
BRPI0813587A2 (pt) Composto, uso do mesmo, e, composição farmacêutica
BRPI0811002A2 (pt) Composição biofertilizante
BRPI0820960A2 (pt) composição
BRPI0909223A2 (pt) uso de catepsaina c