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PL1996621T3 - Przeciwciała przeciwko peptydowi beta amyloidu - Google Patents

Przeciwciała przeciwko peptydowi beta amyloidu

Info

Publication number
PL1996621T3
PL1996621T3 PL07727401T PL07727401T PL1996621T3 PL 1996621 T3 PL1996621 T3 PL 1996621T3 PL 07727401 T PL07727401 T PL 07727401T PL 07727401 T PL07727401 T PL 07727401T PL 1996621 T3 PL1996621 T3 PL 1996621T3
Authority
PL
Poland
Prior art keywords
antibodies against
beta peptide
against amyloid
amyloid
peptide
Prior art date
Application number
PL07727401T
Other languages
English (en)
Inventor
Stephen Anthony Burbidge
Jonathan Henry Ellis
Susannah K Ford
Volker Germaschewski
Umesh Kumar
Karen Louise Philpott
Peter Ernest Soden
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PL1996621T3 publication Critical patent/PL1996621T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL07727401T 2006-03-30 2007-03-27 Przeciwciała przeciwko peptydowi beta amyloidu PL1996621T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78758806P 2006-03-30 2006-03-30
PCT/EP2007/052928 WO2007113172A2 (en) 2006-03-30 2007-03-27 Antibodies against amyloid-beta peptide
EP07727401A EP1996621B1 (en) 2006-03-30 2007-03-27 Antibodies against amyloid-beta peptide

Publications (1)

Publication Number Publication Date
PL1996621T3 true PL1996621T3 (pl) 2010-05-31

Family

ID=38284050

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09178407T PL2177536T3 (pl) 2006-03-30 2007-03-27 Przeciwciała przeciwko peptydowi beta-amyloidu
PL07727401T PL1996621T3 (pl) 2006-03-30 2007-03-27 Przeciwciała przeciwko peptydowi beta amyloidu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL09178407T PL2177536T3 (pl) 2006-03-30 2007-03-27 Przeciwciała przeciwko peptydowi beta-amyloidu

Country Status (32)

Country Link
US (3) US8227576B2 (pl)
EP (2) EP2177536B1 (pl)
JP (1) JP5103466B2 (pl)
KR (2) KR20120093400A (pl)
CN (2) CN101415729B (pl)
AR (1) AR060332A1 (pl)
AT (1) ATE451392T1 (pl)
AU (1) AU2007233831B2 (pl)
BR (1) BRPI0709246A2 (pl)
CA (1) CA2647808C (pl)
CR (1) CR10347A (pl)
CY (1) CY1109877T1 (pl)
DE (1) DE602007003703D1 (pl)
DK (2) DK1996621T3 (pl)
EA (1) EA015654B9 (pl)
ES (2) ES2338179T3 (pl)
HR (2) HRP20100115T1 (pl)
IL (1) IL193695A (pl)
JO (1) JO2576B1 (pl)
MA (1) MA30337B1 (pl)
MX (1) MX2008012483A (pl)
MY (1) MY149630A (pl)
NO (1) NO20083793L (pl)
NZ (1) NZ571038A (pl)
PE (1) PE20080181A1 (pl)
PL (2) PL2177536T3 (pl)
PT (2) PT2177536E (pl)
SI (2) SI1996621T1 (pl)
TW (1) TWI385179B (pl)
UA (1) UA94734C2 (pl)
WO (1) WO2007113172A2 (pl)
ZA (1) ZA200807911B (pl)

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PL1976877T5 (pl) 2005-11-30 2017-09-29 Abbvie Inc Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania
CN117903302A (zh) 2005-11-30 2024-04-19 Abbvie 公司 抗-Aβ球聚体抗体，其相关产品，生产所述抗体的方法，所述抗体的应用以及使用方法
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CN104558172A (zh) * 2015-01-04 2015-04-29 东南大学 一种针对β淀粉样蛋白的单域重链纳米抗体及其应用
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US11382974B2 (en) 2017-08-01 2022-07-12 The Trustees Of Columbia University In The City Of New York Methods and compositions for treatment of amyloid deposition diseases
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
US12018069B2 (en) 2018-06-28 2024-06-25 The Trustees Of Columbia University In The City Of New York Methods and compositions for imaging amyloid deposits
MX2021000235A (es) 2018-07-17 2021-03-25 Jiangsu Hengrui Medicine Co Anticuerpo anti-abeta, fragmento de union a antigeno del mismo y aplicacion del mismo.
CN113874078B (zh) 2019-04-05 2025-05-06 Tauc3生物制品有限公司 抗tauc3抗体及其应用
TW202216760A (zh) 2020-07-23 2022-05-01 愛爾蘭商歐薩爾普羅席納有限公司 抗類澱粉β (ABETA)抗體
TW202300517A (zh) 2021-03-12 2023-01-01 美商美國禮來大藥廠 抗類澱粉β抗體及其用途
WO2022251048A1 (en) 2021-05-24 2022-12-01 Eli Lilly And Company Anti-amyloid beta antibodies and uses thereof
CN114591917B (zh) * 2022-05-07 2022-09-02 北京第一生物化学药业有限公司 产生结合β-淀粉样蛋白的抗体的杂交瘤细胞及其用途
CN114591918B (zh) * 2022-05-07 2022-07-26 北京第一生物化学药业有限公司 产生抗β-淀粉样蛋白抗体的杂交瘤细胞及其用途
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Also Published As

Publication number Publication date
IL193695A (en) 2012-05-31
PT1996621E (pt) 2010-03-08
PL2177536T3 (pl) 2014-11-28
AU2007233831A1 (en) 2007-10-11
HRP20100115T1 (hr) 2010-04-30
NO20083793L (no) 2008-10-13
DK2177536T3 (da) 2014-07-14
EA200801842A1 (ru) 2009-02-27
NZ571038A (en) 2011-03-31
CY1109877T1 (el) 2014-09-10
US20110142824A1 (en) 2011-06-16
HK1138015A1 (en) 2010-08-13
CA2647808A1 (en) 2007-10-11
PT2177536E (pt) 2014-08-22
HK1122311A1 (en) 2009-05-15
TW200815466A (en) 2008-04-01
CN101415729B (zh) 2013-09-04
SI1996621T1 (sl) 2010-04-30
US9193784B2 (en) 2015-11-24
ZA200807911B (en) 2009-11-25
EP2177536A1 (en) 2010-04-21
KR101263294B1 (ko) 2013-06-04
TWI385179B (zh) 2013-02-11
EA015654B1 (ru) 2011-10-31
ES2484967T3 (es) 2014-08-12
ES2338179T3 (es) 2010-05-04
US8227576B2 (en) 2012-07-24
MY149630A (en) 2013-09-13
EP1996621B1 (en) 2009-12-09
SI2177536T1 (sl) 2014-09-30
IL193695A0 (en) 2011-08-01
CN101415729A (zh) 2009-04-22
WO2007113172A2 (en) 2007-10-11
ATE451392T1 (de) 2009-12-15
BRPI0709246A2 (pt) 2011-07-12
CN103539857A (zh) 2014-01-29
CR10347A (es) 2008-10-29
PE20080181A1 (es) 2008-03-16
CA2647808C (en) 2015-11-17
JO2576B1 (en) 2011-02-27
JP5103466B2 (ja) 2012-12-19
KR20080113273A (ko) 2008-12-29
EA015654B9 (ru) 2012-01-30
EP1996621A2 (en) 2008-12-03
AR060332A1 (es) 2008-06-11
US20160024197A1 (en) 2016-01-28
KR20120093400A (ko) 2012-08-22
MA30337B1 (fr) 2009-04-01
JP2009531380A (ja) 2009-09-03
MX2008012483A (es) 2008-10-10
DE602007003703D1 (de) 2010-01-21
UA94734C2 (ru) 2011-06-10
HRP20140618T1 (hr) 2014-08-15
WO2007113172A3 (en) 2007-11-29
US20140050719A1 (en) 2014-02-20
EP2177536B1 (en) 2014-06-04
AU2007233831B2 (en) 2013-02-14
DK1996621T3 (da) 2010-04-19

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GB0625176D0 (en) Peptides
GB0614683D0 (en) Protein