[go: up one dir, main page]

PL1793844T3 - Zastosowanie [d-meala]3-[etval]4-cyklosporyny do leczenia zakażenia wirusem zapalenia wątroby typu c - Google Patents

Zastosowanie [d-meala]3-[etval]4-cyklosporyny do leczenia zakażenia wirusem zapalenia wątroby typu c

Info

Publication number
PL1793844T3
PL1793844T3 PL05791430T PL05791430T PL1793844T3 PL 1793844 T3 PL1793844 T3 PL 1793844T3 PL 05791430 T PL05791430 T PL 05791430T PL 05791430 T PL05791430 T PL 05791430T PL 1793844 T3 PL1793844 T3 PL 1793844T3
Authority
PL
Poland
Prior art keywords
cyclosporin
treatment
infection
etval
meala
Prior art date
Application number
PL05791430T
Other languages
English (en)
Inventor
Pietro Scalfaro
Jean-Maurice Dumont
Grégoire Vuagniaux
Rolland-Yves Mauvernay
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of PL1793844T3 publication Critical patent/PL1793844T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL05791430T 2004-10-01 2005-10-03 Zastosowanie [d-meala]3-[etval]4-cyklosporyny do leczenia zakażenia wirusem zapalenia wątroby typu c PL1793844T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2004003205 2004-10-01
PCT/IB2005/002940 WO2006038088A1 (en) 2004-10-01 2005-10-03 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection and pharmaceutical composition comprising said [d-meala]3-[etval]4-cyclosporin
EP05791430A EP1793844B1 (en) 2004-10-01 2005-10-03 Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection

Publications (1)

Publication Number Publication Date
PL1793844T3 true PL1793844T3 (pl) 2011-05-31

Family

ID=34959441

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05791430T PL1793844T3 (pl) 2004-10-01 2005-10-03 Zastosowanie [d-meala]3-[etval]4-cyklosporyny do leczenia zakażenia wirusem zapalenia wątroby typu c

Country Status (29)

Country Link
US (3) US7439227B2 (pl)
EP (1) EP1793844B1 (pl)
JP (1) JP4892486B2 (pl)
KR (1) KR101191833B1 (pl)
CN (1) CN101056648B (pl)
AT (1) ATE490778T1 (pl)
AU (1) AU2005290984B2 (pl)
BR (1) BRPI0515494A (pl)
CA (1) CA2580448C (pl)
CY (1) CY1114594T1 (pl)
DE (1) DE602005025232D1 (pl)
DK (1) DK1793844T3 (pl)
EA (1) EA012650B1 (pl)
ES (1) ES2357587T3 (pl)
GE (1) GEP20104960B (pl)
HR (1) HRP20110169T1 (pl)
IL (1) IL182362A0 (pl)
MA (1) MA28950B1 (pl)
MX (1) MX2007003387A (pl)
NZ (1) NZ554412A (pl)
PL (1) PL1793844T3 (pl)
PT (1) PT1793844E (pl)
RS (1) RS51614B (pl)
SG (1) SG139750A1 (pl)
SI (1) SI1793844T1 (pl)
TN (1) TNSN07084A1 (pl)
UA (1) UA88484C2 (pl)
WO (1) WO2006038088A1 (pl)
ZA (1) ZA200702610B (pl)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
KR20070036175A (ko) 2004-07-14 2007-04-02 노파르티스 아게 Ｃ형 간염(ｈｃｖ)의 치료를 위한 시클로스포린과ｐｅｇ화된 인터페론의 조합 제제의 용도
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
ATE412005T1 (de) 2004-11-22 2008-11-15 Astellas Pharma Inc Zyklosporinanalog
WO2006071619A1 (en) * 2004-12-23 2006-07-06 Novartis Ag Compositions for hcv treatment
AU2005322241B2 (en) * 2004-12-23 2010-02-18 Novartis Ag Compounds for flaviviridae treatment
CA2611151A1 (en) * 2005-06-17 2006-12-28 Novartis Ag Use of sanglifehrin in hcv
ATE498630T1 (de) 2005-09-30 2011-03-15 Scynexis Inc Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion
CN105169369B (zh) 2005-09-30 2019-10-18 中美华世通生物医药科技（武汉）有限公司 治疗和预防丙型肝炎感染的方法和药物组合物
KR101273681B1 (ko) 2005-10-26 2013-06-25 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
BRPI0710878A2 (pt) 2006-04-11 2015-03-31 Novartis Ag Compostos orgânicos e seus usos
JP5377293B2 (ja) 2006-05-19 2013-12-25 スシネキス インク 眼疾患の治療及び予防方法
AU2007306316B2 (en) * 2006-10-12 2011-10-27 Kyushu University Use of modified cyclosporins
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
CN101687012A (zh) 2007-05-02 2010-03-31 安斯泰来制药有限公司 新的环肽化合物
WO2009042892A1 (en) 2007-09-26 2009-04-02 Oregon Health & Science University Cyclic undecapeptides and derivatives as multiple sclerosis therapies
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2009148615A1 (en) * 2008-06-06 2009-12-10 Scynexis, Inc. Cyclosporin analogs and their use in the treatment of hcv infections
CA2724523A1 (en) 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
JP5758806B2 (ja) * 2008-11-06 2015-08-05 デビオ ルシェルシュ ファルマスーティク ソシエテ アノニムＤｅｂｉｏ Ｒｅｃｈｅｒｃｈｅ Ｐｈａｒｍａｃｅｕｔｉｑｕｅ Ｓｏｃｉｅｔｅ Ａｎｏｎｙｍｅ シクロウンデカデプシペプチド化合物および医薬としてのその化合物の使用
CN102307892A (zh) 2008-12-31 2012-01-04 西尼克斯公司 环孢菌素a的衍生物
JP5406943B2 (ja) 2009-01-30 2014-02-05 エナンタ ファーマシューティカルズ インコーポレイテッド Ｃ型肝炎感染を予防または治療するためのシクロスポリンアナログ
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
WO2011063076A1 (en) 2009-11-19 2011-05-26 Itherx Pharmaceuticals, Inc. Methods of treating hepatitis c virus with oxoacetamide compounds
JP2013513595A (ja) 2009-12-09 2013-04-22 サイネクシス，インコーポレーテッド 新規環状ペプチド
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
WO2011141891A1 (en) 2010-05-12 2011-11-17 Debio Recherche Pharmaceutique S.A. Use of cycloundecadepsipeptide compounds
US9217015B2 (en) 2010-07-16 2015-12-22 S&T Global Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
US9573978B2 (en) 2010-08-12 2017-02-21 S&T Global, Inc. Cyclosporin derivatives for the treatment and prevention of a viral infection
AU2011311706B2 (en) 2010-10-05 2015-11-12 Debiopharm S.A. New treatments of Hepatitis C virus infection
EA201390532A1 (ru) 2010-10-08 2013-09-30 Новартис Аг Композиции сульфамидых ингибиторов ns3, содержащие витамин е
JP6110791B2 (ja) * 2010-11-30 2017-04-05 ノバルティス アーゲー Ｃ型肝炎ウイルス感染症の新規治療
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
JO3337B1 (ar) * 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
MX2013011256A (es) 2011-03-31 2013-10-17 Novartis Ag Alisporivir para el tratamiento de la infeccion por el virus de hepatitis c.
RU2013148779A (ru) 2011-04-01 2015-05-10 Новартис Аг Лечение инфекции вируса гепатита в по отдельности или в комбинации с вирусом гепатита дельта и родственных заболеваний печени
US20150104415A1 (en) * 2011-04-13 2015-04-16 Debiopharm International Sa Treatments of Hepatitis C virus infection
AU2012314517A1 (en) * 2011-09-27 2014-04-17 Novartis Ag Alisporivr for treatment of Hepatis C virus infection
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
DE112012003510T5 (de) 2011-10-21 2015-03-19 Abbvie Inc. Verfahren zur Behandlung von HCV umfassend mindestens zwei direkt wirkende antivirale Wirkstoffe, Ribavirin aber nicht Interferon
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
CN104023726A (zh) 2011-10-21 2014-09-03 艾伯维公司 用于治疗hcv的一种或多种daa的联合治疗(例如，与abt-072或abt-333)
CN104284671A (zh) 2012-05-07 2015-01-14 诺华股份有限公司 使用阿拉泊韦的药代动力学调节
AR090964A1 (es) * 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
US20140205566A1 (en) 2012-11-30 2014-07-24 Novartis Ag Cyclic nucleuoside derivatives and uses thereof
WO2015008223A1 (en) 2013-07-17 2015-01-22 Novartis Ag Treatment of hepatitis c virus infection with alisporivir and ribavirin
EP3038626A4 (en) 2013-08-26 2017-04-19 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c
WO2015136455A1 (en) 2014-03-13 2015-09-17 Novartis Ag New treatments of hepatitis c virus infection
WO2016073480A1 (en) 2014-11-03 2016-05-12 Enanta Pharmaceuticals, Inc. Novel cyclosporin analogues for preventing or treating hepatitis c infection
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
WO2018207904A1 (ja) 2017-05-12 2018-11-15 中外製薬株式会社 環状有機化合物の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757522B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2757520B1 (fr) * 1996-12-24 1999-01-29 Rhone Poulenc Rorer Sa Derive de cyclosporine, sa preparation et les compositions pharmaceutiques qui le contiennent
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
MXPA00013019A (es) * 1998-07-01 2003-07-14 Debiopharm Sa Ciclosporina novedosa con perfil de actividad mejorado.
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
WO2006038088A1 (en) 2006-04-13
PT1793844E (pt) 2011-03-10
HRP20110169T1 (hr) 2011-04-30
KR101191833B1 (ko) 2012-10-16
US20090081164A1 (en) 2009-03-26
EA200700725A1 (ru) 2007-10-26
HK1104236A1 (en) 2008-01-11
ES2357587T3 (es) 2011-04-27
UA88484C2 (ru) 2009-10-26
DE602005025232D1 (de) 2011-01-20
SG139750A1 (en) 2008-02-29
JP4892486B2 (ja) 2012-03-07
AU2005290984A1 (en) 2006-04-13
RS51614B (sr) 2011-08-31
EA012650B1 (ru) 2009-12-30
US7439227B2 (en) 2008-10-21
IL182362A0 (en) 2007-07-24
CA2580448C (en) 2012-09-18
JP2008514690A (ja) 2008-05-08
CN101056648B (zh) 2012-08-15
SI1793844T1 (sl) 2011-05-31
USRE43371E1 (en) 2012-05-08
EP1793844B1 (en) 2010-12-08
ZA200702610B (en) 2008-08-27
EP1793844A1 (en) 2007-06-13
NZ554412A (en) 2011-01-28
CA2580448A1 (en) 2006-04-13
DK1793844T3 (da) 2011-03-21
MX2007003387A (es) 2007-05-23
MA28950B1 (fr) 2007-10-01
GEP20104960B (en) 2010-04-26
CN101056648A (zh) 2007-10-17
CY1114594T1 (el) 2016-10-05
BRPI0515494A (pt) 2008-07-29
TNSN07084A1 (en) 2008-06-02
US20060252675A1 (en) 2006-11-09
KR20070073761A (ko) 2007-07-10
AU2005290984B2 (en) 2010-09-09
US7772184B2 (en) 2010-08-10
ATE490778T1 (de) 2010-12-15

Similar Documents

Publication Publication Date Title
PL1793844T3 (pl) Zastosowanie [d-meala]3-[etval]4-cyklosporyny do leczenia zakażenia wirusem zapalenia wątroby typu c
LT1644009T (lt) Kompozicijos telomerazių aktyvumo didinimui ir živ infekcijos gydymui
WO2005123128A3 (en) Methods for treating conditions associated with masp-2 dependent complement activation
WO2001091728A3 (en) Nanoemulsion formulations
WO2006071613A3 (en) Injectable non-aqueous suspension
WO2005065269A3 (en) Compositions and method for decreasing the appearance of skin wrinkles
WO2006041641A3 (en) Therapeutic agents with decreased toxicity
SG149872A1 (en) Antagonists of the bradykinin b1 receptor
TW200640487A (en) Combination of XOLAIR with immunosuppressive agent
WO2002067971A3 (en) Use of endostatin in the treatment of ocular neovascularization
WO2005121138A3 (en) Heterotricyclic compounds for use as hcv inhibitors
WO2006034001A3 (en) Methods of treating hiv infection
WO2005009366A3 (en) Restoring vascular function
EP2071030A3 (en) Oligoribonucleotide or peptide nucleic acid which inhibits action of hepatitis C virus
WO2007022219A3 (en) Dental composition comprising enzyme
WO2004078927A3 (en) Progenitor cells and methods of using same
SI1729732T1 (sl) Matriksi iz anionskega hidrogela z modificiranim sproĺ äśanjem, odvisnim od ph, kot nosilci za zdravila
WO2005094424A3 (en) Use of the pro-peptide domain of lysyl oxidase as a therapeutic agent
CU20070072A7 (es) Uso de [d-meala]3-[etval]4-ciclosporina para el tratamiento de infección por hepatitis c y composición farmacéutica que comprende la [d-meala]3-[etval]4-ciclosporina
EP1252897A4 (en) MEDICINES FOR GENE THERAPY
JPH10194986A5 (pl)
WO2005000239A3 (en) Lyase treatment for p. carinii
WO2007022140A3 (en) Methods of improving cardiac function and attenuating and/or preventing cardiac remodeling with hsp20
UA93036C2 (ru) Лактамные соединения и применение в качестве фармацевтических препаратов
Kyff Have You Seen the Tree?