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PL1746097T3 - Skondensowane heterocykle 1,4-dihydropirydynowe, sposób ich wytwarzania, zastosowanie i zawierające je kompozycje - Google Patents

Skondensowane heterocykle 1,4-dihydropirydynowe, sposób ich wytwarzania, zastosowanie i zawierające je kompozycje

Info

Publication number
PL1746097T3
PL1746097T3 PL05291558T PL05291558T PL1746097T3 PL 1746097 T3 PL1746097 T3 PL 1746097T3 PL 05291558 T PL05291558 T PL 05291558T PL 05291558 T PL05291558 T PL 05291558T PL 1746097 T3 PL1746097 T3 PL 1746097T3
Authority
PL
Poland
Prior art keywords
dihydropyridine
preparing
same
compositions containing
fused heterocycles
Prior art date
Application number
PL05291558T
Other languages
English (en)
Inventor
Jacques Mauger
Anil Nair
Nina Ma
Kirsten Bjergarde
Bruno Filoche-Romme
Odile Angouillant-Boniface
Serge Mignani
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PL1746097T3 publication Critical patent/PL1746097T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL05291558T 2005-07-20 2005-07-20 Skondensowane heterocykle 1,4-dihydropirydynowe, sposób ich wytwarzania, zastosowanie i zawierające je kompozycje PL1746097T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05291558A EP1746097B1 (en) 2005-07-20 2005-07-20 1,4-dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them

Publications (1)

Publication Number Publication Date
PL1746097T3 true PL1746097T3 (pl) 2010-06-30

Family

ID=35510894

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05291558T PL1746097T3 (pl) 2005-07-20 2005-07-20 Skondensowane heterocykle 1,4-dihydropirydynowe, sposób ich wytwarzania, zastosowanie i zawierające je kompozycje

Country Status (37)

Country Link
US (1) US8163768B2 (pl)
EP (2) EP1746097B1 (pl)
JP (2) JP2009501778A (pl)
KR (1) KR101286796B1 (pl)
CN (1) CN101243087B (pl)
AR (1) AR054845A1 (pl)
AT (2) ATE455115T1 (pl)
AU (1) AU2006273692B8 (pl)
BR (1) BRPI0614002A2 (pl)
CA (1) CA2615700C (pl)
CR (1) CR9663A (pl)
CY (1) CY1109964T1 (pl)
DE (1) DE602005018911D1 (pl)
DK (1) DK1746097T3 (pl)
DO (1) DOP2006000175A (pl)
EA (1) EA016815B1 (pl)
EC (1) ECSP078062A (pl)
ES (1) ES2339676T3 (pl)
HN (1) HN2008000088A (pl)
HR (1) HRP20100195T1 (pl)
IL (1) IL188861A0 (pl)
MA (1) MA29634B1 (pl)
MX (1) MX2008000902A (pl)
MY (1) MY148617A (pl)
NO (1) NO20080831L (pl)
NZ (1) NZ592766A (pl)
PE (2) PE20070212A1 (pl)
PL (1) PL1746097T3 (pl)
PT (1) PT1746097E (pl)
RS (1) RS51351B (pl)
SI (1) SI1746097T1 (pl)
TN (1) TNSN08020A1 (pl)
TW (1) TWI386411B (pl)
UA (1) UA98928C2 (pl)
UY (1) UY29685A1 (pl)
WO (1) WO2007012972A2 (pl)
ZA (1) ZA200800542B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2945535B1 (fr) * 2009-05-18 2011-06-10 Sanofi Aventis Compose anticancereux et composition pharmaceutique le contenant
FR2967413A1 (fr) * 2010-11-17 2012-05-18 Sanofi Aventis Compose 8-oxo-9-[3-(1h-benzimidazol-2-yloxy)-phenyl]-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate d'ethyle, sel, forme cristalline, co-cristal, formulation, procedes de preparation, application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteur des kinases aurora.
MX2014013376A (es) 2012-05-15 2015-08-14 Novartis Ag Derivados de benzamida para inhibir la actividad de abl1, abl2, y bcr-abl1.
US9315489B2 (en) 2012-05-15 2016-04-19 Novartis Ag Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
CN104302638B (zh) 2012-05-15 2016-08-24 诺华股份有限公司 用于抑制abl1、abl2和bcr-abl1的活性的苯甲酰胺衍生物
WO2013171640A1 (en) 2012-05-15 2013-11-21 Novartis Ag Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
PL2909204T3 (pl) * 2012-10-12 2019-07-31 The Broad Institute, Inc. Inhibitory GSK3 i sposoby ich stosowania
WO2016094688A1 (en) 2014-12-10 2016-06-16 Massachusetts Institute Of Technology Fused 1,3-azole derivatives useful for the treatment of proliferative diseases
EP3291676B1 (en) 2015-04-30 2022-08-17 Memorial Sloan Kettering Cancer Center Mitragynine analogs and uses thereof
RU2619932C1 (ru) * 2015-11-25 2017-05-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") ЗАМЕЩЕННЫЕ ПИРАЗОЛО[1,5-а]ПИРИДО[3,4-е]ПИРИМИДИНЫ И ИХ ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ПРОТЕИНКИНАЗ
WO2017124087A1 (en) 2016-01-15 2017-07-20 Memorial Sloan-Kettering Cancer Center Anti-parasitic compounds and uses thereof
EP3416950A1 (en) 2016-02-16 2018-12-26 Massachusetts Institute of Technology Max binders as myc modulators and uses thereof
BR112019020810A2 (pt) 2017-04-05 2020-04-28 The Broad Institute, Inc. compostos tricíclicos como inibidores de glicogênio sintase cinase 3 (gsk3) e usos dos mesmos
AU2018265148A1 (en) * 2017-05-12 2019-10-03 Rti International Diarylureas as CB1 allosteric modulators

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002508324A (ja) * 1997-12-13 2002-03-19 ブリストル−マイヤーズ スクイブ カンパニー サイクリン依存性キナーゼ阻害剤としてのピラゾロ［３，４−ｂ］ピリジンの使用
EP1242422A1 (en) 1999-11-19 2002-09-25 Abbott Laboratories Tricyclic dihydropyrimidine potassium channel openers
US6538004B2 (en) 2000-03-03 2003-03-25 Abbott Laboratories Tricyclic dihydropyrazolone and tricyclic dihydroisoxazolone potassium channel openers
ES2222357T3 (es) 2000-03-03 2005-02-01 Abbott Laboratories Agentes abridores de los canales de potasio a base de dihidropirazolona triciclica y de dihidroisoxazolona triciclica.
JP2005501800A (ja) 2001-02-02 2005-01-20 三菱ウェルファーマ株式会社 ジヒドロピラゾロピリジン化合物およびその医薬用途
FR2823854A1 (fr) * 2001-04-18 2002-10-25 Centre Nat Rech Scient Nouveau procede de criblage d'inhibiteurs de la liaison entre la proteine oxyde nitrique synthase neuronale et la proteine inhibitrice de l'oxyde nitrique synthase neuronale
FR2825091B1 (fr) * 2001-05-23 2003-07-04 Servier Lab Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US7037902B2 (en) * 2002-07-03 2006-05-02 Receptron, Inc. Affinity small molecules for the EPO receptor
SE0301371D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab New Compounds
RU2006100484A (ru) * 2003-06-13 2006-06-10 Центарис ГмбХ, Германи (DE) Соединения, обладающие ингибирующей активностью в отношении фосфатидилинозит-3-киназы, фармацевтическая композиция, способ определения эффективности этих соединений, способ лечения нарушений (варианты) и способ изменения передачи сигнала в клетках

Also Published As

Publication number Publication date
DOP2006000175A (es) 2007-03-31
NO20080831L (no) 2008-04-03
PE20100718A1 (es) 2010-10-20
KR101286796B1 (ko) 2013-07-17
TNSN08020A1 (en) 2009-07-14
IL188861A0 (en) 2008-04-13
US20080261969A1 (en) 2008-10-23
AU2006273692B2 (en) 2012-11-22
TW200740812A (en) 2007-11-01
MA29634B1 (fr) 2008-07-01
ES2339676T3 (es) 2010-05-24
MX2008000902A (es) 2008-03-26
AU2006273692A8 (en) 2012-12-13
EP1746097A1 (en) 2007-01-24
NZ592766A (en) 2012-12-21
ECSP078062A (es) 2008-01-23
EA200800374A1 (ru) 2008-08-29
AU2006273692B8 (en) 2012-12-13
ATE521611T1 (de) 2011-09-15
AR054845A1 (es) 2007-07-18
CY1109964T1 (el) 2014-09-10
MY148617A (en) 2013-05-15
WO2007012972A2 (en) 2007-02-01
HRP20100195T1 (hr) 2010-05-31
CA2615700C (en) 2013-06-18
UY29685A1 (es) 2007-02-28
UA98928C2 (ru) 2012-07-10
SI1746097T1 (sl) 2010-05-31
CN101243087B (zh) 2013-07-24
US8163768B2 (en) 2012-04-24
DK1746097T3 (da) 2010-05-25
ATE455115T1 (de) 2010-01-15
EP1746097B1 (en) 2010-01-13
JP2013063987A (ja) 2013-04-11
CR9663A (es) 2008-02-21
CN101243087A (zh) 2008-08-13
EA016815B1 (ru) 2012-07-30
EP1910366B1 (en) 2011-08-24
DE602005018911D1 (de) 2010-03-04
EP1910366A2 (en) 2008-04-16
WO2007012972A3 (en) 2007-04-05
PT1746097E (pt) 2010-04-15
KR20080026658A (ko) 2008-03-25
RS51351B (sr) 2011-02-28
HN2008000088A (es) 2011-05-31
AU2006273692A1 (en) 2007-02-01
ZA200800542B (en) 2010-02-24
TWI386411B (zh) 2013-02-21
BRPI0614002A2 (pt) 2011-03-01
PE20070212A1 (es) 2007-03-21
CA2615700A1 (en) 2007-02-01
JP2009501778A (ja) 2009-01-22

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