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FR2825091B1 - Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Info

Publication number
FR2825091B1
FR2825091B1 FR0106792A FR0106792A FR2825091B1 FR 2825091 B1 FR2825091 B1 FR 2825091B1 FR 0106792 A FR0106792 A FR 0106792A FR 0106792 A FR0106792 A FR 0106792A FR 2825091 B1 FR2825091 B1 FR 2825091B1
Authority
FR
France
Prior art keywords
quinnoleins
dihydro
pharmaceutical compositions
preparation process
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0106792A
Other languages
English (en)
Other versions
FR2825091A1 (fr
Inventor
Henri Philippe Husson
Renault Sylviane Giorgi
Stephanie Desbene
John Hickman
Alain Pierre
Berthier Laurence Kraus
Bruno Pfeiffer
Pierre Renard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0106792A priority Critical patent/FR2825091B1/fr
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to EA200301171A priority patent/EA200301171A1/ru
Priority to CA002448191A priority patent/CA2448191A1/fr
Priority to CNA028102746A priority patent/CN1511158A/zh
Priority to BR0209974-8A priority patent/BR0209974A/pt
Priority to CZ20033495A priority patent/CZ20033495A3/cs
Priority to KR10-2003-7015306A priority patent/KR20030097898A/ko
Priority to HU0400436A priority patent/HUP0400436A2/hu
Priority to MXPA03010599A priority patent/MXPA03010599A/es
Priority to PCT/FR2002/001715 priority patent/WO2002094835A1/fr
Priority to EP02740805A priority patent/EP1389210A1/fr
Priority to US10/477,258 priority patent/US20040198981A1/en
Priority to JP2002591508A priority patent/JP2004535405A/ja
Priority to SK1602-2003A priority patent/SK16022003A3/sk
Priority to PL02364082A priority patent/PL364082A1/xx
Priority to ARP020101906A priority patent/AR033915A1/es
Publication of FR2825091A1 publication Critical patent/FR2825091A1/fr
Application granted granted Critical
Publication of FR2825091B1 publication Critical patent/FR2825091B1/fr
Priority to ZA200308629A priority patent/ZA200308629B/en
Priority to NO20035215A priority patent/NO20035215L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D497/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR0106792A 2001-05-23 2001-05-23 Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related FR2825091B1 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR0106792A FR2825091B1 (fr) 2001-05-23 2001-05-23 Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US10/477,258 US20040198981A1 (en) 2001-05-23 2002-05-22 Tricyclic dihydroquinoline derivatives,method for preparing same and pharmaceutical compositions containing same
CNA028102746A CN1511158A (zh) 2001-05-23 2002-05-22 三环类二氢喹啉衍生物、其制备方法以及包含它们的药物组合物
BR0209974-8A BR0209974A (pt) 2001-05-23 2002-05-22 Derivados tricìclicos de dihidro-quinoleìnas, o respectivo processo de preparação e as composições farmacêuticas que os contêm
CZ20033495A CZ20033495A3 (en) 2001-05-23 2002-05-22 Tricyclic dihydro-quinoline derivatives, method for preparing same and pharmaceutical compositions containing same
KR10-2003-7015306A KR20030097898A (ko) 2001-05-23 2002-05-22 트리시클릭 디히드로퀴놀린 유도체, 이의 제조 방법 및이를 함유하는 약제 조성물
HU0400436A HUP0400436A2 (hu) 2001-05-23 2002-05-22 Új triciklusos dihidrokinolin-vegyületek, eljárás a vegyületek előállítására és a vegyületeket tartalmazó gyógyászati készítmények
MXPA03010599A MXPA03010599A (es) 2001-05-23 2002-05-22 Derivados tiriciclicos de dihidroquinolinas, metodo para prepararlos y composiciones farmaceuticas que los contienen.
PCT/FR2002/001715 WO2002094835A1 (fr) 2001-05-23 2002-05-22 Nouveaux derives tricycliques de dihydro-quinoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SK1602-2003A SK16022003A3 (sk) 2001-05-23 2002-05-22 Tricyklické dihydrochinolínové zlúčeniny, spôsob ich prípravy a farmaceutické kompozície, ktoré ich obsahujú
EA200301171A EA200301171A1 (ru) 2001-05-23 2002-05-22 Новые соединения трициклических дигидрохинолинов, способ их получения и фармацевтические композиции, содержащие их
CA002448191A CA2448191A1 (fr) 2001-05-23 2002-05-22 Nouveaux derives tricycliques de dihydro-quinoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP02740805A EP1389210A1 (fr) 2001-05-23 2002-05-22 Nouveaux derives tricycliques de dihydro-quinoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PL02364082A PL364082A1 (en) 2001-05-23 2002-05-22 Tricyclic dihydro-quinoline derivatives, method for preparing same and pharmaceutical compositions containing same
JP2002591508A JP2004535405A (ja) 2001-05-23 2002-05-22 新しい三環式ジヒドロキノリン化合物、これらの製造方法及びこれらを含む医薬組成物
ARP020101906A AR033915A1 (es) 2001-05-23 2002-05-23 Compuestos triciclicos dihidroquinolina, un procedimiento para su preparacion y composiciones farmaceuticas que los contienen
ZA200308629A ZA200308629B (en) 2001-05-23 2003-11-05 Tricyclic dihydro-quinoline derivatives, method for preparing same and pharmaceutical compositions containing same.
NO20035215A NO20035215L (no) 2001-05-23 2003-11-24 Tricykliske dihydrokinolinforbindelser, fremgangsmåte for deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0106792A FR2825091B1 (fr) 2001-05-23 2001-05-23 Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
FR2825091A1 FR2825091A1 (fr) 2002-11-29
FR2825091B1 true FR2825091B1 (fr) 2003-07-04

Family

ID=8863589

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0106792A Expired - Fee Related FR2825091B1 (fr) 2001-05-23 2001-05-23 Nouveaux derives tricycliques de dihydro-quinnoleines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (18)

Country Link
US (1) US20040198981A1 (fr)
EP (1) EP1389210A1 (fr)
JP (1) JP2004535405A (fr)
KR (1) KR20030097898A (fr)
CN (1) CN1511158A (fr)
AR (1) AR033915A1 (fr)
BR (1) BR0209974A (fr)
CA (1) CA2448191A1 (fr)
CZ (1) CZ20033495A3 (fr)
EA (1) EA200301171A1 (fr)
FR (1) FR2825091B1 (fr)
HU (1) HUP0400436A2 (fr)
MX (1) MXPA03010599A (fr)
NO (1) NO20035215L (fr)
PL (1) PL364082A1 (fr)
SK (1) SK16022003A3 (fr)
WO (1) WO2002094835A1 (fr)
ZA (1) ZA200308629B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1746097B1 (fr) * 2005-07-20 2010-01-13 Aventis Pharma S.A. Héterocyles à fusion1,4-dihydropyridineprocédé de préparation, utilisation et compositions de celles-ci
US8927560B2 (en) 2010-12-06 2015-01-06 Council Of Scientific & Industrial Research 4-Aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof
AU2015205995A1 (en) 2014-01-15 2016-07-28 Centre National De La Recherche Scientifique (Cnrs) Water soluble 4-azapodophyllotoxin analogs
US11098052B2 (en) 2016-03-02 2021-08-24 Arizona Board Of Regents On Behalf Of Arizona State University 4-azapodophylotoxins compounds
CN111494374B (zh) * 2020-06-12 2021-08-03 广东省微生物研究所（广东省微生物分析检测中心） 香草木宁碱在制备破骨细胞分化抑制剂中的应用
CN114989180B (zh) * 2022-05-26 2024-06-04 广东海洋大学 杨叶肖槿内生真菌来源的化合物及其制备方法与应用
CN119698420A (zh) * 2022-07-12 2025-03-25 俄勒冈健康与科学大学 偶氮鬼臼毒素衍生物su056的对映异构体
US11731980B1 (en) 2023-03-22 2023-08-22 King Faisal University Furo[3,4-b]quinolone compounds as antibacterial agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801310B1 (fr) * 1999-11-24 2004-04-16 Adir NOUVEAUX DERIVES DE DIHYDROFURO-[3,4-b]QUINOLEIN-1-ONES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT

Also Published As

Publication number Publication date
MXPA03010599A (es) 2004-03-09
ZA200308629B (en) 2004-11-05
EA200301171A1 (ru) 2004-04-29
JP2004535405A (ja) 2004-11-25
FR2825091A1 (fr) 2002-11-29
PL364082A1 (en) 2004-12-13
CN1511158A (zh) 2004-07-07
WO2002094835A1 (fr) 2002-11-28
BR0209974A (pt) 2004-04-06
EP1389210A1 (fr) 2004-02-18
AR033915A1 (es) 2004-01-07
NO20035215D0 (no) 2003-11-24
KR20030097898A (ko) 2003-12-31
NO20035215L (no) 2003-11-24
CA2448191A1 (fr) 2002-11-28
US20040198981A1 (en) 2004-10-07
CZ20033495A3 (en) 2004-05-12
HUP0400436A2 (hu) 2004-09-28
SK16022003A3 (sk) 2004-05-04

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20060131