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PH24451A - New pteridines and their use as pharmaceuticla agents - Google Patents

New pteridines and their use as pharmaceuticla agents

Info

Publication number
PH24451A
PH24451A PH33161A PH33161A PH24451A PH 24451 A PH24451 A PH 24451A PH 33161 A PH33161 A PH 33161A PH 33161 A PH33161 A PH 33161A PH 24451 A PH24451 A PH 24451A
Authority
PH
Philippines
Prior art keywords
pharmaceuticla
agents
pteridines
new
new pteridines
Prior art date
Application number
PH33161A
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Muller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of PH24451A publication Critical patent/PH24451A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PH33161A 1984-12-12 1985-12-11 New pteridines and their use as pharmaceuticla agents PH24451A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (en) 1984-12-12 1984-12-12 NEW PTERIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF AS INTERMEDIATE PRODUCTS OR AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
PH24451A true PH24451A (en) 1990-06-25

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33161A PH24451A (en) 1984-12-12 1985-12-11 New pteridines and their use as pharmaceuticla agents

Country Status (15)

Country Link
EP (1) EP0185259A3 (en)
JP (1) JPS61140585A (en)
AU (1) AU576924B2 (en)
CA (1) CA1252783A (en)
DE (1) DE3445298A1 (en)
DK (1) DK161327C (en)
ES (1) ES8707238A1 (en)
FI (1) FI82696C (en)
GR (1) GR852996B (en)
IL (1) IL77294A (en)
NO (1) NO161373C (en)
NZ (1) NZ214522A (en)
PH (1) PH24451A (en)
PT (1) PT81650B (en)
ZA (1) ZA859462B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
HUP0700040A2 (en) 2001-06-28 2007-05-29 Essential Therapeutics Fused pyrimidines as d-alanyl-d-alanine ligase inhibitors, and process for producing them
DE10202468A1 (en) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridine derivatives, process for their preparation and their use
CA2534151A1 (en) * 2003-08-29 2005-03-10 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
WO2005039587A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
CA2555867A1 (en) * 2004-03-04 2005-09-22 Neurogen Corporation Arylalkylamino-substituted quinazoline analogues
DE102004057595A1 (en) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituted pteridines for the treatment of inflammatory diseases
DE102004057618A1 (en) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituted pteridines for the treatment of inflammatory diseases
DE102004057645A1 (en) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg New substituted pteridine compounds, useful as phosphodiesterase 4 inhibitors for treating e.g. inflammatory diseases, cancer, asthma, ulcerative colitis, depression and schizophrenia
DE102004057594A1 (en) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitute pteridine for the treatment of inflammatory diseases
RU2445315C2 (en) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AND USE THEREOF AS mTOR INHIBITORS
JP5161102B2 (en) * 2005-11-22 2013-03-13 クドス ファーマシューティカルズ リミテッド Pyridopyrimidine, pyrazopyrimidine and pyrimidopyrimidine derivatives as mTOR inhibitors
CA2652840C (en) 2006-05-24 2014-09-09 Boehringer Ingelheim International Gmbh 2-piperazino-6-chloro-pteridines as pde4-inhibitors for the treatment of inflammatory diseases
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
KR101438245B1 (en) 2006-08-23 2014-09-04 쿠도스 파마슈티칼스 리미티드 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as MTOR inhibitors
TWI441821B (en) 2008-06-20 2014-06-21 Astrazeneca Ab Process for the preparation of pyrido-pyrimidine compounds
SI3321265T1 (en) 2015-03-04 2020-07-31 Gilead Sciences, Inc. 4,6-diamino-pyrido(3,2-d)pyrimidine compounds and their utilisation as modulators of toll-like receptors
JP6746776B2 (en) 2016-09-02 2020-08-26 ギリアード サイエンシーズ, インコーポレイテッド Toll-like receptor modulator compound
ES2826748T3 (en) 2016-09-02 2021-05-19 Gilead Sciences Inc Derivatives of 4,6-diamino-pyrido [3,2-d] pyrimidine as modulators of Toll-like receptors
TWI751517B (en) 2019-04-17 2022-01-01 美商基利科學股份有限公司 Solid forms of a toll-like receptor modulator
TWI751516B (en) 2019-04-17 2022-01-01 美商基利科學股份有限公司 Solid forms of a toll-like receptor modulator
TWI879779B (en) 2019-06-28 2025-04-11 美商基利科學股份有限公司 Processes for preparing toll-like receptor modulator compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (en) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach NEW 2-PIPERAZINO-PTERIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND

Also Published As

Publication number Publication date
DK161327B (en) 1991-06-24
JPS61140585A (en) 1986-06-27
DK572685D0 (en) 1985-12-11
DK572685A (en) 1986-06-13
PT81650A (en) 1986-01-01
EP0185259A3 (en) 1989-03-01
ES549806A0 (en) 1987-07-16
FI82696C (en) 1991-04-10
CA1252783A (en) 1989-04-18
ES8707238A1 (en) 1987-07-16
AU5123285A (en) 1986-06-19
DE3445298A1 (en) 1986-06-12
FI82696B (en) 1990-12-31
NO161373C (en) 1989-08-09
FI854862A0 (en) 1985-12-10
ZA859462B (en) 1987-07-29
NZ214522A (en) 1988-07-28
AU576924B2 (en) 1988-09-08
NO161373B (en) 1989-05-02
NO854965L (en) 1986-06-13
PT81650B (en) 1988-04-21
GR852996B (en) 1986-04-16
DK161327C (en) 1991-12-09
IL77294A (en) 1989-02-28
FI854862A7 (en) 1986-06-13
EP0185259A2 (en) 1986-06-25

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