[go: up one dir, main page]

DK161327C - SUBSTITUTED 2-PIPERAZINOPTERIDINES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINALS CONTAINING THE COMPOUNDS - Google Patents

SUBSTITUTED 2-PIPERAZINOPTERIDINES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINALS CONTAINING THE COMPOUNDS

Info

Publication number
DK161327C
DK161327C DK572685A DK572685A DK161327C DK 161327 C DK161327 C DK 161327C DK 572685 A DK572685 A DK 572685A DK 572685 A DK572685 A DK 572685A DK 161327 C DK161327 C DK 161327C
Authority
DK
Denmark
Prior art keywords
piperazinopteridines
procedures
substituted
preparing
compounds
Prior art date
Application number
DK572685A
Other languages
Danish (da)
Other versions
DK161327B (en
DK572685D0 (en
DK572685A (en
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK572685D0 publication Critical patent/DK572685D0/en
Publication of DK572685A publication Critical patent/DK572685A/en
Publication of DK161327B publication Critical patent/DK161327B/en
Application granted granted Critical
Publication of DK161327C publication Critical patent/DK161327C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK572685A 1984-12-12 1985-12-11 SUBSTITUTED 2-PIPERAZINOPTERIDINES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINALS CONTAINING THE COMPOUNDS DK161327C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (en) 1984-12-12 1984-12-12 NEW PTERIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF AS INTERMEDIATE PRODUCTS OR AS A MEDICINAL PRODUCT
DE3445298 1984-12-12

Publications (4)

Publication Number Publication Date
DK572685D0 DK572685D0 (en) 1985-12-11
DK572685A DK572685A (en) 1986-06-13
DK161327B DK161327B (en) 1991-06-24
DK161327C true DK161327C (en) 1991-12-09

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
DK572685A DK161327C (en) 1984-12-12 1985-12-11 SUBSTITUTED 2-PIPERAZINOPTERIDINES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINALS CONTAINING THE COMPOUNDS

Country Status (15)

Country Link
EP (1) EP0185259A3 (en)
JP (1) JPS61140585A (en)
AU (1) AU576924B2 (en)
CA (1) CA1252783A (en)
DE (1) DE3445298A1 (en)
DK (1) DK161327C (en)
ES (1) ES8707238A1 (en)
FI (1) FI82696C (en)
GR (1) GR852996B (en)
IL (1) IL77294A (en)
NO (1) NO161373C (en)
NZ (1) NZ214522A (en)
PH (1) PH24451A (en)
PT (1) PT81650B (en)
ZA (1) ZA859462B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
HUP0700040A2 (en) 2001-06-28 2007-05-29 Essential Therapeutics Fused pyrimidines as d-alanyl-d-alanine ligase inhibitors, and process for producing them
DE10202468A1 (en) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridine derivatives, process for their preparation and their use
CA2534151A1 (en) * 2003-08-29 2005-03-10 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
WO2005039587A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
CA2555867A1 (en) * 2004-03-04 2005-09-22 Neurogen Corporation Arylalkylamino-substituted quinazoline analogues
DE102004057595A1 (en) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituted pteridines for the treatment of inflammatory diseases
DE102004057618A1 (en) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituted pteridines for the treatment of inflammatory diseases
DE102004057645A1 (en) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg New substituted pteridine compounds, useful as phosphodiesterase 4 inhibitors for treating e.g. inflammatory diseases, cancer, asthma, ulcerative colitis, depression and schizophrenia
DE102004057594A1 (en) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitute pteridine for the treatment of inflammatory diseases
RU2445315C2 (en) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AND USE THEREOF AS mTOR INHIBITORS
JP5161102B2 (en) * 2005-11-22 2013-03-13 クドス ファーマシューティカルズ リミテッド Pyridopyrimidine, pyrazopyrimidine and pyrimidopyrimidine derivatives as mTOR inhibitors
CA2652840C (en) 2006-05-24 2014-09-09 Boehringer Ingelheim International Gmbh 2-piperazino-6-chloro-pteridines as pde4-inhibitors for the treatment of inflammatory diseases
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
KR101438245B1 (en) 2006-08-23 2014-09-04 쿠도스 파마슈티칼스 리미티드 2-methylmorpholine pyrido-, pyrazo- and pyrimido-pyrimidine derivatives as MTOR inhibitors
TWI441821B (en) 2008-06-20 2014-06-21 Astrazeneca Ab Process for the preparation of pyrido-pyrimidine compounds
SI3321265T1 (en) 2015-03-04 2020-07-31 Gilead Sciences, Inc. 4,6-diamino-pyrido(3,2-d)pyrimidine compounds and their utilisation as modulators of toll-like receptors
JP6746776B2 (en) 2016-09-02 2020-08-26 ギリアード サイエンシーズ， インコーポレイテッド Toll-like receptor modulator compound
ES2826748T3 (en) 2016-09-02 2021-05-19 Gilead Sciences Inc Derivatives of 4,6-diamino-pyrido [3,2-d] pyrimidine as modulators of Toll-like receptors
TWI751517B (en) 2019-04-17 2022-01-01 美商基利科學股份有限公司 Solid forms of a toll-like receptor modulator
TWI751516B (en) 2019-04-17 2022-01-01 美商基利科學股份有限公司 Solid forms of a toll-like receptor modulator
TWI879779B (en) 2019-06-28 2025-04-11 美商基利科學股份有限公司 Processes for preparing toll-like receptor modulator compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (en) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach NEW 2-PIPERAZINO-PTERIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THIS COMPOUND

Also Published As

Publication number Publication date
DK161327B (en) 1991-06-24
JPS61140585A (en) 1986-06-27
DK572685D0 (en) 1985-12-11
DK572685A (en) 1986-06-13
PT81650A (en) 1986-01-01
EP0185259A3 (en) 1989-03-01
ES549806A0 (en) 1987-07-16
FI82696C (en) 1991-04-10
CA1252783A (en) 1989-04-18
ES8707238A1 (en) 1987-07-16
AU5123285A (en) 1986-06-19
DE3445298A1 (en) 1986-06-12
FI82696B (en) 1990-12-31
NO161373C (en) 1989-08-09
FI854862A0 (en) 1985-12-10
ZA859462B (en) 1987-07-29
NZ214522A (en) 1988-07-28
AU576924B2 (en) 1988-09-08
NO161373B (en) 1989-05-02
NO854965L (en) 1986-06-13
PT81650B (en) 1988-04-21
GR852996B (en) 1986-04-16
PH24451A (en) 1990-06-25
IL77294A (en) 1989-02-28
FI854862A7 (en) 1986-06-13
EP0185259A2 (en) 1986-06-25

Similar Documents

Publication Publication Date Title
DK161327C (en) SUBSTITUTED 2-PIPERAZINOPTERIDINES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINALS CONTAINING THE COMPOUNDS
NO171364C (en) N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOL-1-CARBOXAMIDES AND PROCEDURES FOR PREPARING THEREOF, AND THE INSECTANT CONTAINING THE CARBOXAMIDE
DK165248C (en) 1,3,9,9A-TETRAHYDRO-IMIDAZOOE4,5-BAAQUINOLIN-2-ONER AND PROCEDURE FOR PREPARING THEREOF
DK355485A (en) DINATE-3-AMINO-L-HYDROXY-PROPAN-1,1-DIPHOSPHONATE AND PROCEDURES FOR PREPARING THEREOF
NO167034C (en) PROCEDURE FOR PREPARING 1,6-DICHLOR-1,6-DIDEOXY-BETA-D-FRUCTOFURANOSYL-4-CHLORO-4-DIOXY-ALFA-GALACTOPYRANOSIDE
DK273587A (en) 1,5-DIARYL-3-SUBSTITUTED PYRAZOLES AND PROCEDURES FOR PREPARING THEREOF
FI852317L (en) CONTAINER FRAMSTAELLNING AV MIKROKAPSELDISPERSIONER.
NO861114L (en) PROCEDURE FOR PREPARING POLYISOCYANATE-POLYISOCYANURATES.
FI865020A0 (en) ANORDINATION FOR THE PAPPERSBANA SPETSDRAGNING AV.
DK475685A (en) SUBSTITUTED BENZYLETHERS, PESTICIDES CONTAINING THESE COMPOUNDS AND PROCEDURES FOR THEIR PREPARATION
DK206785A (en) BENZAZEPINE DERIVATIVES, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURES FOR PREPARING THEREOF
DK163057C (en) ISOINDSOLINYL-ALKYL PIPERAZINES, PROCEDURES FOR PREPARING THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME
NO854924L (en) PROCEDURE FOR PREPARING EMULSIONS.
FI854888A0 (en) ANORDINATION FOR INKOPPLING AV EN HJAELPBRYTARE.
DK431185A (en) SUBSTITUTED QUINAZOL INDONES AND PROCEDURES FOR PREPARING THEREOF
DK451684D0 (en) QUINAZOLINE DERIVATIVES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINES CONTAINING THESE COMPOUNDS
DK115685D0 (en) PRESPAP AND PROCEDURES FOR PREPARING THEREOF
DK490385A (en) 6-PHENETHYLAMINOALKYL-FURO- (3,4-C) -PYRIDINE DERIVATIVES, PROCEDURES FOR PREPARING IT, AND MEDICINALS CONTAINING SUCH COMPOUNDS
NO164238C (en) PROCEDURE FOR PREPARING PYRIDOBENZODIAZEPINE COMPOUNDS.
NO864695D0 (en) PROCEDURE FOR PREPARING 2,2 [-BI-1H-IMIDAZOLES.
DK51785A (en) 1,4-AMINOALKYLAMINO-9H-THIOXANTHEN-9-ONER, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURES FOR PREPARING THEREOF
FI851520L (en) ANORDINATION FOR SAMMANPRESSNING AV EN BLAOSFOLIESLANG.
DK164670C (en) PYRROLOOE3,2,1-HIAAINDOL DERIVATIVES, PROCEDURES FOR PREPARING THEREOF, AND MEDICINES CONTAINING SUCH COMPOUNDS
DK165554C (en) QUINOLIZIN-4-ON COMPOUNDS, PROCEDURES FOR THE PRODUCTION THEREOF, PREPARATIONS CONTAINING THE COMPOUNDS, PROCEDURES FOR THE PREPARATION OF THE PREPARATIONS AND USE OF THE COMPOUNDS
NO864307D0 (en) PROCEDURE FOR PREPARING 5-HETEROCYCLIC-2,4-DIALKYL-3H-1,2,4-TRIAZOL-3-THIONER.

Legal Events

Date Code Title Description
PBP Patent lapsed