PE20170140A1 - Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer - Google Patents
Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancerInfo
- Publication number
- PE20170140A1 PE20170140A1 PE2017000058A PE2017000058A PE20170140A1 PE 20170140 A1 PE20170140 A1 PE 20170140A1 PE 2017000058 A PE2017000058 A PE 2017000058A PE 2017000058 A PE2017000058 A PE 2017000058A PE 20170140 A1 PE20170140 A1 PE 20170140A1
- Authority
- PE
- Peru
- Prior art keywords
- agent
- cancer
- tigit
- seq
- methods
- Prior art date
Links
- 101000831007 Homo sapiens T-cell immunoreceptor with Ig and ITIM domains Proteins 0.000 title abstract 3
- 102100024834 T-cell immunoreceptor with Ig and ITIM domains Human genes 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 title 2
- 201000011510 cancer Diseases 0.000 title 2
- 239000003112 inhibitor Substances 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 229940122815 Aromatase inhibitor Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000013059 antihormonal agent Substances 0.000 abstract 1
- 239000003886 aromatase inhibitor Substances 0.000 abstract 1
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- Peptides Or Proteins (AREA)
Abstract
La presente divulgacion provee metodos que comprenden la administracion al individuo de un agente que reduce o inhibe la actividad y/o la expresion de TIGIT tal como un anticuerpo anti-TIGIT que comprende al menos una HVR con una secuencia de aminoacidos SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, entre otros y un agente contra el cancer tal como un agente alquilante, un agente antihormonal, un inhibidor de aromatasa, entre otros. Tambien se proveen kits que comprenden un agente contra el cancer, un agente que reduce o inhibe la actividad y/o la expresion de TIGIT, o ambas, asi como instrucciones para su uso
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462025394P | 2014-07-16 | 2014-07-16 |
Publications (1)
| Publication Number | Publication Date |
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| PE20170140A1 true PE20170140A1 (es) | 2017-03-30 |
Family
ID=55079055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| PE2017000058A PE20170140A1 (es) | 2014-07-16 | 2015-07-16 | Metodos para tratar el cancer con inhibidores de tigit y agentes contra el cancer |
Country Status (19)
| Country | Link |
|---|---|
| US (9) | US20170143825A1 (es) |
| EP (1) | EP3169363A4 (es) |
| JP (4) | JP2017522311A (es) |
| KR (1) | KR20170023081A (es) |
| CN (1) | CN107073108A (es) |
| AU (1) | AU2015289621A1 (es) |
| BR (1) | BR112017000703A2 (es) |
| CA (1) | CA2953245A1 (es) |
| CL (1) | CL2017000080A1 (es) |
| CO (1) | CO2017001493A2 (es) |
| CR (1) | CR20170014A (es) |
| EA (1) | EA201790195A1 (es) |
| IL (1) | IL249658A0 (es) |
| MA (1) | MA40437A (es) |
| MX (1) | MX2016017288A (es) |
| PE (1) | PE20170140A1 (es) |
| PH (1) | PH12017500070A1 (es) |
| SG (2) | SG10201811841UA (es) |
| WO (1) | WO2016011264A1 (es) |
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| AR093788A1 (es) * | 2012-12-04 | 2015-06-24 | Oncomed Pharm Inc | Inmunoterapia con agentes de enlace |
-
2015
- 2015-07-16 EP EP15822079.8A patent/EP3169363A4/en not_active Withdrawn
- 2015-07-16 MX MX2016017288A patent/MX2016017288A/es unknown
- 2015-07-16 MA MA040437A patent/MA40437A/fr unknown
- 2015-07-16 CA CA2953245A patent/CA2953245A1/en not_active Abandoned
- 2015-07-16 BR BR112017000703A patent/BR112017000703A2/pt not_active IP Right Cessation
- 2015-07-16 KR KR1020177001261A patent/KR20170023081A/ko not_active Withdrawn
- 2015-07-16 CN CN201580036081.3A patent/CN107073108A/zh active Pending
- 2015-07-16 PE PE2017000058A patent/PE20170140A1/es unknown
- 2015-07-16 SG SG10201811841UA patent/SG10201811841UA/en unknown
- 2015-07-16 CR CR20170014A patent/CR20170014A/es unknown
- 2015-07-16 EA EA201790195A patent/EA201790195A1/ru unknown
- 2015-07-16 SG SG11201700258VA patent/SG11201700258VA/en unknown
- 2015-07-16 JP JP2017502120A patent/JP2017522311A/ja not_active Withdrawn
- 2015-07-16 WO PCT/US2015/040770 patent/WO2016011264A1/en not_active Ceased
- 2015-07-16 AU AU2015289621A patent/AU2015289621A1/en not_active Abandoned
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2016
- 2016-12-20 IL IL249658A patent/IL249658A0/en unknown
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2017
- 2017-01-10 PH PH12017500070A patent/PH12017500070A1/en unknown
- 2017-01-10 US US15/402,662 patent/US20170143825A1/en not_active Abandoned
- 2017-01-12 CL CL2017000080A patent/CL2017000080A1/es unknown
- 2017-02-14 CO CONC2017/0001493A patent/CO2017001493A2/es unknown
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2018
- 2018-02-07 US US15/890,852 patent/US20180169239A1/en not_active Abandoned
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2020
- 2020-04-08 US US16/843,604 patent/US20200289647A1/en not_active Abandoned
- 2020-06-16 JP JP2020103978A patent/JP2020180127A/ja active Pending
- 2020-12-11 US US17/118,799 patent/US20210113693A1/en not_active Abandoned
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2021
- 2021-12-07 JP JP2021198263A patent/JP2022046494A/ja not_active Withdrawn
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2022
- 2022-06-01 US US17/830,065 patent/US20220331426A1/en not_active Abandoned
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2023
- 2023-01-13 US US18/154,581 patent/US20230226180A1/en not_active Abandoned
- 2023-10-13 US US18/486,230 patent/US20240082396A1/en not_active Abandoned
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2024
- 2024-02-26 JP JP2024026145A patent/JP2024075568A/ja active Pending
- 2024-06-05 US US18/734,042 patent/US20240307534A1/en not_active Abandoned
- 2024-12-12 US US18/978,156 patent/US20250108111A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA201790195A1 (ru) | 2017-09-29 |
| AU2015289621A1 (en) | 2017-01-12 |
| SG11201700258VA (en) | 2017-02-27 |
| CR20170014A (es) | 2017-10-17 |
| CO2017001493A2 (es) | 2017-07-11 |
| MA40437A (fr) | 2017-05-24 |
| US20200289647A1 (en) | 2020-09-17 |
| US20210113693A1 (en) | 2021-04-22 |
| SG10201811841UA (en) | 2019-02-27 |
| US20180169239A1 (en) | 2018-06-21 |
| JP2020180127A (ja) | 2020-11-05 |
| BR112017000703A2 (pt) | 2017-11-14 |
| CL2017000080A1 (es) | 2017-06-23 |
| US20240082396A1 (en) | 2024-03-14 |
| JP2024075568A (ja) | 2024-06-04 |
| US20250108111A1 (en) | 2025-04-03 |
| US20230226180A1 (en) | 2023-07-20 |
| JP2017522311A (ja) | 2017-08-10 |
| IL249658A0 (en) | 2017-02-28 |
| KR20170023081A (ko) | 2017-03-02 |
| US20220331426A1 (en) | 2022-10-20 |
| CA2953245A1 (en) | 2016-01-21 |
| CN107073108A (zh) | 2017-08-18 |
| US20240307534A1 (en) | 2024-09-19 |
| WO2016011264A1 (en) | 2016-01-21 |
| PH12017500070A1 (en) | 2017-05-15 |
| MX2016017288A (es) | 2017-06-27 |
| US20170143825A1 (en) | 2017-05-25 |
| EP3169363A4 (en) | 2018-02-21 |
| JP2022046494A (ja) | 2022-03-23 |
| EP3169363A1 (en) | 2017-05-24 |
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