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PE20130147A1 - PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT - Google Patents

PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT

Info

Publication number
PE20130147A1
PE20130147A1 PE2012000649A PE2012000649A PE20130147A1 PE 20130147 A1 PE20130147 A1 PE 20130147A1 PE 2012000649 A PE2012000649 A PE 2012000649A PE 2012000649 A PE2012000649 A PE 2012000649A PE 20130147 A1 PE20130147 A1 PE 20130147A1
Authority
PE
Peru
Prior art keywords
theobromine
pharmaceutical combination
opioid
antitussive agent
combination
Prior art date
Application number
PE2012000649A
Other languages
Spanish (es)
Inventor
John Brew
Robin Mark Bannister
Original Assignee
Biocopea Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41509324&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20130147(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biocopea Ltd filed Critical Biocopea Ltd
Publication of PE20130147A1 publication Critical patent/PE20130147A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMBINACION FARMACEUTICA QUE COMPRENDE A) TEOBROMINA; Y B) UN ANTITUSIVO NO OPIATO TAL COMO DEXTROMETORFANO, ISOAMILO, MORCLOFONA, CLOFEDANOL, ENTRE OTROS, EN UNA CANTIDAD DE 0,1 A 30 MG/KG/DIA. DICHA COMBINACION PRESENTA UN EFECTO SINERGICO A COMPARACION DE LA ADMINISTRACION POR SEPARADO Y REDUCE LAS DOSIS INDIVIDUALES EN EL TRATAMIENTO DE LA TOSIT REFERS TO A PHARMACEUTICAL COMBINATION THAT INCLUDES A) THEOBROMINE; AND B) A NON-OPIATE ANTITUSSIVE SUCH AS DEXTROMETORPHANE, ISOAMYL, MORCHLOFONE, CLOFEDANOL, AMONG OTHERS, IN AN AMOUNT OF 0.1 TO 30 MG / KG / DAY. SUCH COMBINATION PRESENTS A SYNERGIC EFFECT IN COMPARISON OF SEPARATE ADMINISTRATION AND REDUCES INDIVIDUAL DOSES IN THE TREATMENT OF COUGH

PE2012000649A 2009-11-13 2010-11-12 PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT PE20130147A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0919889.6A GB0919889D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy

Publications (1)

Publication Number Publication Date
PE20130147A1 true PE20130147A1 (en) 2013-03-13

Family

ID=41509324

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000649A PE20130147A1 (en) 2009-11-13 2010-11-12 PHARMACEUTICAL COMBINATION OF THEOBROMINE AND A NON-OPIOID ANTITUSSIVE AGENT

Country Status (17)

Country Link
EP (1) EP2498777A2 (en)
JP (2) JP2013510841A (en)
CN (1) CN102753174A (en)
AU (1) AU2010317667B2 (en)
BR (1) BR112012011227A2 (en)
CA (1) CA2780703A1 (en)
CO (1) CO6551744A2 (en)
GB (1) GB0919889D0 (en)
IL (1) IL219768A0 (en)
MX (1) MX2012005532A (en)
NZ (1) NZ599949A (en)
PE (1) PE20130147A1 (en)
PH (1) PH12012501369A1 (en)
RU (1) RU2519086C2 (en)
UA (1) UA108993C2 (en)
WO (1) WO2011058373A2 (en)
ZA (1) ZA201204248B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
WO2017117347A1 (en) * 2015-12-30 2017-07-06 Markovitz M D Paul Method of treating schizophrenia

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834479A (en) * 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
ATE286885T1 (en) * 1996-11-25 2005-01-15 Procter & Gamble GUANIDYL HETEROCYCLIC COMPOUNDS AS ALPHA-2 ADRENOCEPTOR AGONISTS
HUP9700654A2 (en) * 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
US20030206942A1 (en) * 1998-09-25 2003-11-06 Neema Kulkarni Fast dissolving orally consumable films containing an antitussive and a mucosa coating agent
US6207674B1 (en) * 1999-12-22 2001-03-27 Richard A. Smith Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants
EP1646428B1 (en) * 2003-05-29 2008-04-09 Unilever Plc Hair treatment compositions
US20060153926A1 (en) * 2005-01-10 2006-07-13 Bascom Charles C Compositions, products and methods for controlling weight in a mammal
US20080003280A1 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs
US20080176955A1 (en) * 2007-01-16 2008-07-24 Victory Pharma, Inc. Combined administration of benzonatate and guaifenesin

Also Published As

Publication number Publication date
EP2498777A2 (en) 2012-09-19
CO6551744A2 (en) 2012-10-31
RU2519086C2 (en) 2014-06-10
IL219768A0 (en) 2012-07-31
WO2011058373A2 (en) 2011-05-19
JP2016128439A (en) 2016-07-14
AU2010317667B2 (en) 2014-05-29
UA108993C2 (en) 2015-07-10
ZA201204248B (en) 2013-02-27
NZ599949A (en) 2013-08-30
BR112012011227A2 (en) 2017-06-13
CA2780703A1 (en) 2011-05-19
MX2012005532A (en) 2012-09-28
GB0919889D0 (en) 2009-12-30
RU2012124038A (en) 2013-12-20
CN102753174A (en) 2012-10-24
JP6118919B2 (en) 2017-04-19
WO2011058373A3 (en) 2011-07-07
JP2013510841A (en) 2013-03-28
AU2010317667A1 (en) 2012-06-07
PH12012501369A1 (en) 2012-10-22

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