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PE20090317A1 - Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos - Google Patents

Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos

Info

Publication number
PE20090317A1
PE20090317A1 PE2008000908A PE2008000908A PE20090317A1 PE 20090317 A1 PE20090317 A1 PE 20090317A1 PE 2008000908 A PE2008000908 A PE 2008000908A PE 2008000908 A PE2008000908 A PE 2008000908A PE 20090317 A1 PE20090317 A1 PE 20090317A1
Authority
PE
Peru
Prior art keywords
soluble
iron
water
complex
production
Prior art date
Application number
PE2008000908A
Other languages
English (en)
Inventor
Stefan Reim
Erik Philipp
Felix Funk
Hans-Martin Muller
Peter Geisser
Original Assignee
Vifor Int Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38287550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20090317(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vifor Int Ag filed Critical Vifor Int Ag
Publication of PE20090317A1 publication Critical patent/PE20090317A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00Preparation of derivatives of starch
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00Preparation of derivatives of starch
    • C08B31/18Oxidised starch
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00Preparation of derivatives of starch
    • C08B31/18Oxidised starch
    • C08B31/185Derivatives of oxidised starch, e.g. crosslinked oxidised starch

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UN COMPLEJO DE HIERRO Y UN CARBOHIDRATO TAL COMO MALTODEXTRINAS QUE ES SOLUBLE EN AGUA, Y A UN PROCEDIMIENTO DE PREPARACION DE DICHO COMPLEJO QUE COMPRENDE: A) OXIDACION DE UNA O VARIAS MALTODEXTRINAS EN SOLUCION ACUOSA A UN PH ALCALINO CON UNA SOLUCION ACUOSA DE HIPOCLORITO; B) DERIVATIZACION DE LA MALTODEXTRINA OXIDADA EN PRESENCIA DE IONES BROMURO MEDIANTE ESTERIFICACION CON ACIDOS ORGANICOS E INORGANICOS, OXIDACION, CARBOXIALQUILACION, AMIDACION, ENTRE OTROS PROCEDIMIENTOS; Y C) MEZCLAR LA MALTODEXTRINA DERIVATIZADA OXIDADA CON UNA SAL DE HIERRO (III) TAL COMO CARBURO DE HIERRO (III). SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA QUE CONTIENE DICHO COMPLEJO SOLUBLE DE HIERRO Y EL DERIVADO DE CARBOHIDRATO UTIL EN EL TRATAMIENTO DE ESTADOS DE DEFICIENCIA DE HIERRO
PE2008000908A 2007-05-29 2008-05-28 Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos PE20090317A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07109081A EP1997833A1 (de) 2007-05-29 2007-05-29 Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PE20090317A1 true PE20090317A1 (es) 2009-04-24

Family

ID=38287550

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2008000908A PE20090317A1 (es) 2007-05-29 2008-05-28 Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos

Country Status (26)

Country Link
US (1) US8263577B2 (es)
EP (2) EP1997833A1 (es)
JP (1) JP5259700B2 (es)
KR (1) KR101168085B1 (es)
CN (1) CN101679530B (es)
AR (1) AR065997A1 (es)
AU (1) AU2008257683B2 (es)
BR (1) BRPI0811985B8 (es)
CA (1) CA2682587C (es)
CL (1) CL2008001549A1 (es)
CO (1) CO6241161A2 (es)
ES (1) ES2547304T3 (es)
GT (1) GT200900308A (es)
IL (1) IL201294A (es)
MA (1) MA31456B1 (es)
MX (1) MX2009012889A (es)
MY (1) MY158004A (es)
NZ (1) NZ581487A (es)
PE (1) PE20090317A1 (es)
PL (1) PL2148890T3 (es)
PT (1) PT2148890E (es)
RU (1) RU2441881C2 (es)
TN (1) TN2009000443A1 (es)
TW (1) TWI372621B (es)
WO (1) WO2008145586A1 (es)
ZA (1) ZA200907672B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10249552A1 (de) * 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
CA2953964A1 (en) 2006-01-06 2007-07-19 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
CN109700828A (zh) 2009-03-25 2019-05-03 法码科思莫斯控股有限公司 稳定的铁寡糖复合物
EP2496595A2 (en) * 2009-11-04 2012-09-12 Symed Labs Limited Process for the preparation of iron (iii) carboxymaltose complex
PH12012501814A1 (en) 2010-03-23 2012-12-10 Vifor Int Ag Fe(iii) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias
CN101891832B (zh) * 2010-07-22 2012-01-04 山东农业大学 一种无碱均相生产氧化淀粉方法
WO2012104204A1 (en) 2011-01-31 2012-08-09 Vifor (International) Ag Iron-carbohydrate complex compounds for the intravenous therapy of malaria
EP2766183A4 (en) 2011-10-13 2015-07-01 Vidasym Inc IRON FIBER COMPOSITION, PREPARATION THEREOF AND USES THEREOF
US9796792B2 (en) 2013-03-08 2017-10-24 Vidasym, Inc. Metal ion-functional fiber component complex compositions, preparation and uses thereof
US9370202B2 (en) * 2013-03-15 2016-06-21 LG Bionano, LLC Encapsulated metal ion nanoclusters
CN107438626A (zh) * 2015-03-23 2017-12-05 苏文生命科学有限公司 水溶性三价铁碳水化合物复合物的制备
CN105125577B (zh) * 2015-07-29 2018-05-18 南京生命能科技开发有限公司 一种稳定的糖-铁复合物及其制备方法
CN105520955B (zh) * 2015-12-21 2018-05-11 南京生命能科技开发有限公司 一种羧基麦芽糖铁药用组合物及其制备方法
WO2019193608A1 (en) * 2018-04-05 2019-10-10 Msn Laboratories Private Limited, R&D Center Improved process for the preparation of iron (iii) carboxymaltose
CN115368477B (zh) * 2021-05-21 2023-05-02 武汉科福新药有限责任公司 高得率、高含铁量的羧基麦芽糖铁的制备方法
CN115368478B (zh) * 2021-05-21 2023-07-04 武汉科福新药有限责任公司 一种羧基麦芽糖铁的制备方法
CN115322265A (zh) * 2022-08-29 2022-11-11 滨州学院 一种羧基麦芽糖控制性氧化与纯化工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172860B1 (da) * 1998-03-25 1999-08-16 Pharmacosmos Holding As Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
DE10249552A1 (de) * 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
US7964568B2 (en) * 2003-05-30 2011-06-21 Chromaceutical Advanced Technologies, Inc. Synthesis of high molecular weight iron-saccharidic complexes
ITMO20050056A1 (it) 2005-03-15 2006-09-16 Biofer Spa Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
EP1757299A1 (de) 2005-08-25 2007-02-28 Vifor (International) Ag Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung

Also Published As

Publication number Publication date
AU2008257683A1 (en) 2008-12-04
RU2009149175A (ru) 2011-07-10
ES2547304T3 (es) 2015-10-05
WO2008145586A1 (de) 2008-12-04
CA2682587C (en) 2013-05-14
IL201294A0 (en) 2010-05-31
MX2009012889A (es) 2009-12-10
HK1140219A1 (en) 2010-10-08
BRPI0811985B1 (pt) 2020-04-07
CO6241161A2 (es) 2011-01-20
MA31456B1 (fr) 2010-06-01
EP2148890B1 (de) 2015-08-19
US8263577B2 (en) 2012-09-11
BRPI0811985A2 (pt) 2014-11-18
ZA200907672B (en) 2010-07-28
AR065997A1 (es) 2009-07-15
MY158004A (en) 2016-08-30
RU2441881C2 (ru) 2012-02-10
BRPI0811985B8 (pt) 2021-05-25
TN2009000443A1 (en) 2011-03-31
CN101679530A (zh) 2010-03-24
IL201294A (en) 2013-06-27
KR101168085B1 (ko) 2012-07-24
TW200900055A (en) 2009-01-01
PL2148890T3 (pl) 2016-01-29
KR20100010502A (ko) 2010-02-01
CL2008001549A1 (es) 2009-09-25
AU2008257683B2 (en) 2012-06-21
GT200900308A (es) 2011-09-06
EP1997833A1 (de) 2008-12-03
TWI372621B (en) 2012-09-21
JP5259700B2 (ja) 2013-08-07
CN101679530B (zh) 2012-07-04
US20100305063A1 (en) 2010-12-02
CA2682587A1 (en) 2008-12-04
PT2148890E (pt) 2015-10-15
JP2010528166A (ja) 2010-08-19
NZ581487A (en) 2012-04-27
EP2148890A1 (de) 2010-02-03

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