MX2009012889A - Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos. - Google Patents
Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos.Info
- Publication number
- MX2009012889A MX2009012889A MX2009012889A MX2009012889A MX2009012889A MX 2009012889 A MX2009012889 A MX 2009012889A MX 2009012889 A MX2009012889 A MX 2009012889A MX 2009012889 A MX2009012889 A MX 2009012889A MX 2009012889 A MX2009012889 A MX 2009012889A
- Authority
- MX
- Mexico
- Prior art keywords
- medicaments
- water
- mixture
- carbohydrate derivative
- preparation
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229920002774 Maltodextrin Polymers 0.000 abstract 4
- 229920002245 Dextrose equivalent Polymers 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000005913 Maltodextrin Substances 0.000 abstract 2
- 238000001212 derivatisation Methods 0.000 abstract 2
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 2
- 229940035034 maltodextrin Drugs 0.000 abstract 2
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical class [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 abstract 1
- 206010022971 Iron Deficiencies Diseases 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un complejo de hierro y derivado de carbohidrato, soluble en agua, obtenible a partir de la solución acuosa de sal de hierro (III) y una solución acuosa del producto de oxidación y la derivatización subsiguiente de una o varias maltodextrinas con una solución acuosa de hipoclorito a un valor de pH alcalino, en donde, con el empleo de una maltodextrina cuyo equivalente de dextrosa se encuentra entre 5 y 20 y con el empleo de una mezcla de varias maltodextrinas, el equivalente de dextrosa de la mezcla se encuentra entre 5 y 20 y el equivalente de dextrosa de cada maltodextrina individual que forma parte de la mezcla se encuentra entre 2 y 40, y se lleva a cabo la derivatización subsiguiente con un reactivo adecuado, procedimiento para su producción y medicamentos para el tratamiento y la profilaxis de estados de deficiencia de hierro.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109081A EP1997833A1 (de) | 2007-05-29 | 2007-05-29 | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| PCT/EP2008/056276 WO2008145586A1 (de) | 2007-05-29 | 2008-05-21 | Wasserlösliche eisen-kohlenhydratderivat-komplexe, deren herstellung und diese enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009012889A true MX2009012889A (es) | 2009-12-10 |
Family
ID=38287550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009012889A MX2009012889A (es) | 2007-05-29 | 2008-05-21 | Complejos de hierro y derivados de carbohidrato, solubles en agua, su produccion y medicamentos que contienen los mismos. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8263577B2 (es) |
| EP (2) | EP1997833A1 (es) |
| JP (1) | JP5259700B2 (es) |
| KR (1) | KR101168085B1 (es) |
| CN (1) | CN101679530B (es) |
| AR (1) | AR065997A1 (es) |
| AU (1) | AU2008257683B2 (es) |
| BR (1) | BRPI0811985B8 (es) |
| CA (1) | CA2682587C (es) |
| CL (1) | CL2008001549A1 (es) |
| CO (1) | CO6241161A2 (es) |
| ES (1) | ES2547304T3 (es) |
| GT (1) | GT200900308A (es) |
| IL (1) | IL201294A (es) |
| MA (1) | MA31456B1 (es) |
| MX (1) | MX2009012889A (es) |
| MY (1) | MY158004A (es) |
| NZ (1) | NZ581487A (es) |
| PE (1) | PE20090317A1 (es) |
| PL (1) | PL2148890T3 (es) |
| PT (1) | PT2148890E (es) |
| RU (1) | RU2441881C2 (es) |
| TN (1) | TN2009000443A1 (es) |
| TW (1) | TWI372621B (es) |
| WO (1) | WO2008145586A1 (es) |
| ZA (1) | ZA200907672B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| AU2007205167B2 (en) | 2006-01-06 | 2013-06-13 | Vifor (International) Ag | Methods and compositions for administration of iron |
| ES3009818T3 (en) | 2009-03-25 | 2025-04-01 | Pharmacosmos Holding As | An oligosaccharide and a process for preparation thereof |
| WO2011055374A2 (en) * | 2009-11-04 | 2011-05-12 | Symed Labs Limited | Process for the preparation of iron (iii) carboxymaltose complex |
| ES2660202T3 (es) | 2010-03-23 | 2018-03-21 | Vifor (International) Ag | Compuestos del complejo Fe (iii) para el tratamiento y la profilaxis de los síntomas de deficiencia de hierro y las anemias ferropénicas |
| CN101891832B (zh) * | 2010-07-22 | 2012-01-04 | 山东农业大学 | 一种无碱均相生产氧化淀粉方法 |
| WO2012104204A1 (en) | 2011-01-31 | 2012-08-09 | Vifor (International) Ag | Iron-carbohydrate complex compounds for the intravenous therapy of malaria |
| JP6189309B2 (ja) * | 2011-10-13 | 2017-08-30 | ヴィダシム・インコーポレーテッド | 鉄−繊維組成物、その調製および使用 |
| CN105007759B (zh) | 2013-03-08 | 2018-11-20 | 上海礼邦医药科技有限公司 | 金属离子-功能性纤维组分络合物组合物、其制备及用途 |
| US9370202B2 (en) | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
| EP3274372A1 (en) * | 2015-03-23 | 2018-01-31 | Suven Life Sciences Limited | Preparation of water soluble trivalent iron carbohydrate complexes |
| CN105125577B (zh) * | 2015-07-29 | 2018-05-18 | 南京生命能科技开发有限公司 | 一种稳定的糖-铁复合物及其制备方法 |
| CN105520955B (zh) * | 2015-12-21 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种羧基麦芽糖铁药用组合物及其制备方法 |
| WO2019193608A1 (en) * | 2018-04-05 | 2019-10-10 | Msn Laboratories Private Limited, R&D Center | Improved process for the preparation of iron (iii) carboxymaltose |
| CN115368478B (zh) * | 2021-05-21 | 2023-07-04 | 武汉科福新药有限责任公司 | 一种羧基麦芽糖铁的制备方法 |
| CN115368477B (zh) * | 2021-05-21 | 2023-05-02 | 武汉科福新药有限责任公司 | 高得率、高含铁量的羧基麦芽糖铁的制备方法 |
| CN115322265A (zh) * | 2022-08-29 | 2022-11-11 | 滨州学院 | 一种羧基麦芽糖控制性氧化与纯化工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DE10249552A1 (de) * | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| ITMO20050056A1 (it) * | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
| EP1757299A1 (de) * | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
-
2007
- 2007-05-29 EP EP07109081A patent/EP1997833A1/de not_active Withdrawn
-
2008
- 2008-04-09 AR ARP080101467A patent/AR065997A1/es not_active Application Discontinuation
- 2008-04-30 TW TW097115868A patent/TWI372621B/zh not_active IP Right Cessation
- 2008-05-21 CA CA2682587A patent/CA2682587C/en not_active Expired - Fee Related
- 2008-05-21 MX MX2009012889A patent/MX2009012889A/es active IP Right Grant
- 2008-05-21 EP EP08759877.7A patent/EP2148890B1/de not_active Not-in-force
- 2008-05-21 RU RU2009149175/05A patent/RU2441881C2/ru active
- 2008-05-21 US US12/599,343 patent/US8263577B2/en active Active
- 2008-05-21 BR BRPI0811985A patent/BRPI0811985B8/pt not_active IP Right Cessation
- 2008-05-21 JP JP2010509794A patent/JP5259700B2/ja not_active Expired - Fee Related
- 2008-05-21 WO PCT/EP2008/056276 patent/WO2008145586A1/de not_active Ceased
- 2008-05-21 KR KR1020097023006A patent/KR101168085B1/ko not_active Expired - Fee Related
- 2008-05-21 PL PL08759877T patent/PL2148890T3/pl unknown
- 2008-05-21 CN CN2008800178628A patent/CN101679530B/zh not_active Expired - Fee Related
- 2008-05-21 MY MYPI20094711A patent/MY158004A/en unknown
- 2008-05-21 ES ES08759877.7T patent/ES2547304T3/es active Active
- 2008-05-21 NZ NZ581487A patent/NZ581487A/en not_active IP Right Cessation
- 2008-05-21 AU AU2008257683A patent/AU2008257683B2/en not_active Ceased
- 2008-05-21 PT PT87598777T patent/PT2148890E/pt unknown
- 2008-05-28 CL CL2008001549A patent/CL2008001549A1/es unknown
- 2008-05-28 PE PE2008000908A patent/PE20090317A1/es not_active Application Discontinuation
-
2009
- 2009-10-01 IL IL201294A patent/IL201294A/en not_active IP Right Cessation
- 2009-10-22 CO CO09118656A patent/CO6241161A2/es active IP Right Grant
- 2009-10-23 TN TNP2009000443A patent/TN2009000443A1/fr unknown
- 2009-11-02 ZA ZA200907672A patent/ZA200907672B/xx unknown
- 2009-11-27 GT GT200900308A patent/GT200900308A/es unknown
- 2009-12-21 MA MA32435A patent/MA31456B1/fr unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |